Peripheral Neuropathy - Biotech, Pharma and Life Science Channel
PubMed Articles
Critical Roles of a Dendritic Cell Subset Expressing a Chemokine Receptor, XCR1.
Dendritic cells (DCs) consist of various subsets that play crucial roles in linking innate and adaptive immunity. In the murine spleen, CD8α(+) DCs exhibit a propensity to ingest dying/dead cells, pr...
CRYAB, a small heat shock protein, was previously shown to decrease neuroinflammation in experimental allergic encephalomyelitis (EAE). We investigated whether the expression of cell adhesion molecule...
Lymphoma is one of the most common forms of cancer in dogs as it is in humans but, unlike humans, the cure rates in canines are still very low. Despite the fact that high grade B-cell lymphomas are co...
Melatonin is known as an antistress and immunostimulator compound while glucocorticoids have immunosuppressive function. The mechanism of action of both the hormones on immune cells is still a questio...
Transcriptional regulation of the peripheral nervous system in Ciona intestinalis.
The formation of the sensory organs and cells that make up the peripheral nervous system (PNS) relies on the activity of transcription factors encoded by proneural genes (PNGs). Although PNGs have bee...
Spondyloarthritis and inflammatory bowel disease : Comorbidity and treatment implications.
Spondyloarthritides (SpA) and inflammatory bowel disease (IBD) are chronic, idiopathic inflammatory disorders of the axial and peripheral joints and the intestinal tract, respectively, affecting up to...
Steroidal and non-steroidal anti-inflammatory drugs are used for treatment of peripheral inflammation, but they are not effective in neurodegenerative disorders. Gold compounds are also used to treat...
Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox.
Diabetes mellitus (DM) is a chronic metabolic disease characterized by the presence of hyperglycemia, which can lead to many complications over time. These complications, such as nephropathy, retinopa...
Genetic analysis of auditory neuropathy spectrum disorder in the Korean population.
Auditory neuropathy spectrum disorder (ANSD) is caused by dys-synchronous auditory neural response as a result of impairment of the functions of the auditory nerve or inner hair cells, or synapses bet...
Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord.
Amorphous mesoporous silica nanoparticles ('protocells') that support surface lipid bilayers recently characterized in vitro as carrier constructs for small drug and DNA delivery are reported here as...
News Articles
Acute leg ischaemia may present without pain in some cases
The excellent account of acute leg ischaemia would not be complete without mentioning that acute leg ischaemia can have a pain-free presentation.1 2 3 4A report of 330 unselected cases of peripheral.....
Chiropractor in Stuart, FL Now Offering Revolutionary Treatment for Back and Neck Pain Relief
The premier chiropractor in Stuart, FL, Wiedner Family chiropractic, is now offering spinal decompression therapy. This treatment has been revolutionary for pain relief acute and chronic back and neck...
By Jacob Steinberg:Today, I am going to cover LeMaitre Vascular (LMAT) in my "can this stock double" series. LeMaitre Vascular develops, manufactures and markets vascular devices that can treat periph...
[News] Acetyl-L-carnitine ineffective in treatment of CIPN
Previous studies had indicated that Acetyl-L-carnitine (ALC), a natural agent that enhances neuronal protection, might be a useful treatment option for patients with chemotherapy-induced peripheral ne...
Targeted Medical Pharma Engages Marcum LLP as New Auditors
Targeted Medical Pharma, Inc. (OTCQB: TRGM), a biotechnology company that develops and distributes prescription medical foods to physicians and pharmacies, today announced...
Drug-Eluting Stents Show Promise in Peripheral Artery Disease
A new study demonstrates superior short-term results with drug eluting stents compared with bare metal stents in the treatment of...
Santa Monica Pain Clinic, Advanced Pain Management, Joins CA Pain Network and Accepting New Patients
The leading pain clinic in Santa Monica, Advanced Pain Management, has joined the CA Pain Network and is now accepting new patients. The clinic accepts both self pay pain management patients along wit...
Top Cape Coral Pain Clinic, Community Wellness, Now Offering Self Pay Pain Management Treatment
The leading pain management clinic serving Cape Coral Fl, Community Wellness, is now offering self pay pain management treatment. Community Wellness is offering initial visits for only $150, and new p...
Neuracelâs Ultimate Neuropathy Support System Aims to Alleviate Neuropathy Pain
Boise, Idaho (PRWEB) June 13, 2013 A disorder of the nerves, Neuropathy is amongst one of the biggest challenges currently faced by medical experts. The severity of the problem that neuropathy pres...
Cardiovascular Systems to Release Late-Breaking Coronary Data at C3 Conference
CSI Also Provided Educational Grant for Conference Lunch Symposium Cardiovascular Systems, Inc. (CSI) (NASDAQ: CSII), will present data from its ORBIT II study of coronary art...
Events
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Companies
NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...
Based in Medford, Mass., AngioLight is an interventional cardiology medical device company founded to address unmet clinical needs in coronary and peripheral stenting. The company...
NeuroMetrix is a science-based health care company transforming patient care through neurotechnology. To date, our focus has been primarily on the assessment of neuropathies. We a...
Based in Brisbane, California, XDx is a molecular diagnostics company focused on the discovery, development and commercialization of noninvasive gene expression-based tests for th...
Itamar Medical Ltd. is a publicly-traded medical technology company utilizing PAT⢠(Peripheral Arterial Tone) signal technology and applications. The PAT signal is a non-inva...
Flexible Stenting Solutions Inc.
Flexible Stenting Solutions Inc. (FSS) is a leading developer of third-generation flexible peripheral arterial and biliary stents. Its fully connected stent has coupled technology...
Itamar Medical Ltd. is a publicly-traded medical technology company (TASE: ITMR) utilizing PAT⢠(Peripheral Arterial Tone) signal technology and applications. The PAT signal...
Pamlab, L.L.C., founded in 1957, is a fully integrated pharmaceutical company specializing in medical foods indicated for specific disease states including diabetic neuropathy, de...
Pamlab, L.L.C., founded in 1957, is a fully integrated pharmaceutical company specializing in medical foods indicated for the nutritional support of specific disease states includ...
Founded in 2005 by cardiologists and researchers from the Stanford University School of Medicine , Aviir is focused on the discovery, development and commercialization of innovati...
Clinical Trials
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may...
Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis
This study will use positron emission tomography (PET) to measure a brain protein called peripheral benzodiazepine receptor (PBR) in patients with multiple sclerosis. PBR is created during...
The VISIBILITY Iliac study is a prospective, multi-center, non-randomized study confirming the safety and effectiveness of stenting using the Visi-Pro™ Balloon Expandable Stent System fo...
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with periphe...
This randomized phase II trial is studying how well giving tacrolimus and mycophenolate mofetil (MMF) together with or without sirolimus works in preventing acute graft-versus-host disease...
This study will evaluate the safety and effectiveness of treating patients with severe aplastic anemia (SAA) or myelopdysplastic syndrome (MDS) with both peripheral blood stem cells from a...
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and he...
Differentiation Induction in Acute Myelogenous Leukemia
Hypothesis: Differentiation induction therapy in acute myelogenous leukemia (AML) can be used to achieve disease control and stabilize peripheral blood counts in patients with acute myelog...
CASPAR : Clopidogrel and Acetyl Salicylic Acid in Bypass Surgery for Peripheral ARterial Disease
Primary objective: To evaluate whether clopidogrel 75 mg o.d. versus placebo (on a background of ASA 75-100 mg/d) will lead to an increased rate of primary patency, limb salvage and survi...
The Effects of Ramipril on Clinical Symptoms in Patients With Peripheral Arterial Disease
One important clinical challenge in older individuals is maintaining mobility in the absence of pain. Peripheral arterial disease affects up to 12% of adults over 50 and impairs quality of...
Videos
Peripheral Neuropathy
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Medical and Biotech [MESH] Definitions
Peripheral Blood Stem Cell Transplantation
Transplantation of stem cells collected from the peripheral blood. It is a less invasive alternative to direct marrow harvesting of hematopoietic stem cells. Enrichment of stem cells in peripheral blood can be achieved by inducing mobilization of stem cells from the BONE MARROW.
Nerve Fibers, Unmyelinated
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the unmyelinated nerve fibers are small. The axons to SCHWANN CELLS ratio is greater in the unmyelinated nerve fibers than that in the myelinated fiber (NERVE FIBERS, MYELINATED) which is 1:1. Usually several axons are surrounded by a single Schwann cell in the unmyelinated nerve fibers. Therefore, each unmyelinated fiber is not completely covered by the MYELIN SHEATH formed by the Schwann cell. Unmyelinated nerve fibers conduct impulses at low velocities. They represent the majority of peripheral sensory and autonomic fibers. They are also found in the spinal cord and brain.
Receptor, Muscarinic M1
A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING.
Receptor, Cannabinoid, Cb1
A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.
Receptor, Serotonin, 5-ht2a
A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.
