Pipelines - Biotech, Pharma and Life Science Channel
News Articles
FDA Helps Women Get Heart Smart
FDA's Office of Women's Health offers many resources to educate women about the safe use of FDA-approved drugs and devices for the treatment and prevention of heart disease. This includes information...
Isis Pharmaceuticals to Present at the Deutsche Bank 38th Annual dbAccess Health Care Conference
CARLSBAD, Calif., May 23, 2013 /PRNewswire/ -- Isis Pharmaceuticals, Inc. (NASDAQ: ISIS), the leader in antisense therapeutics, today announced that management will present a company overview at the D...
New funding for Cardiff researchers to develop new drugs to treat osteoarthritis
Medical research charity Arthritis Research UK has awarded a team of researchers at Cardiff University a grant of £200,000 to investigate new drugs to treat early onset osteoarthritis. The team...
FARMINGTON, Conn., May 22, 2013 /PRNewswire-iReach/ -- World markets are constantly changing and developing. To stay aligned with the latest trends and events, companies now need a global business int...
Fitch: Pace of Drug Approvals to Moderate for Global Pharmaceutical Companies
Link to Fitch Ratings' Report: Global Pharmaceutical R&D Pipelinehttp://www.fitchratings.com/creditdesk/reports/report_frame.cfm?rpt_id=708623 Global pharmaceutical novel dr...
Orion Corporation is preparing to issue a bond
ORION CORPORATION STOCK EXCHANGE RELEASE 20 MAY 2013 at 09.50 EEST Orion Corporation is preparing to issue a EUR 100-150 million senior, unsecured bond that w...
225,000 Orion A-shares converted into B-shares
ORION CORPORATION STOCK EXCHANGE RELEASE 20 MAY 2013 at 09.15 a.m. EEST In accordance with Section 3 of the Articles of Association of Orion Corporation, 225...
Home Secretary is Ignoring Advice Over Legal Highs Including her Experts
LONDON, May 16, 2013 /PRNewswire/ -- Founder of the drugs charity, Angelus, Maryon Stewart, described the Home Secretary as, "ignoring advice over Legal Highs including her own experts." The Chair of...
Combination of osteoporosis drugs 'better than either on its own'
A combination of the drugs teriparatide and denosumab appears to be better at increasing bone mineral density in postmenopausal women with the bone-thinning disease osteoporosis than either drug on it...
Nuvilex, Inc. Cell Encapsulation Could Mimic Combination Chemotherapy
NEW YORK, NY -- (Marketwired) -- 05/15/13 -- Nuvilex, Inc. (OTCQB: NVLX) has had its living cell encapsulation or "Cell-in-a-Box" technology tested again and again, and each time it has proven it can...
Companies
BioInvent International is a unique company dedicated to working with clients to ensure their success in the discovery, development and manufacture of antibody drugs. The discovery of new drug targets...
Perosphere is a specialty pharmaceutical company that identifies and develops new chemical entities and other therapeutics that can be used as ârescueâ drugs. For more i...
Aradigm Corporation and Grifols S.A.
Aradigm is an emerging specialty pharmaceutical company focused on the development and commercialization of drugs delivered by inhalation for the prevention and treatment of sever...
Monarch Medical Technologies is a privately held medical technology company founded by clinicians with a vision of dramatically improving hospital-based glucose management by repl...
R-Tech Ueno is a bio-venture company established in September 1989 for the purpose of marketing and R&D of drugs. Under leadership of the president, also a medical doctor, the company is developing ne...
Xenetic is a leading UK-based biopharmaceutical company providing leading-edge expertise in the development of a whole new generation of drugs and vaccines. Working with some of the largest pharma...
Verastem, Inc. is a private biopharmaceutical company focused on discovering and developing novel drugs that selectively target cancer stem cells. Cancer stem cells are an underly...
Etubics Corporation, based in Seattle, Wash., is a clinical stage bio-pharmaceutical company, which has developed a proprietary platform technology consisting of a next generation...
TPP is a UK-based, drug development company operating in the preclinical area of the drug discovery process. TPP in-licenses novel intellectual property (IP) from universities, re...
Ipsen is a global biopharmaceutical group, with sales exceeding 1 billion euros in 2009. The Group has total worldwide staff of more than 4,400 employees, of which nearly 900 cont...
Clinical Trials
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
RATIONALE: Androgens can cause the growth of prostate cancer cells. Drugs, such as goserelin, may stop the adrenal glands from making androgens. Drugs used in chemotherapy, such as docetax...
Pixantrone or Other Chemotherapy Drugs in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. It is not yet known whether...
RATIONALE: Drugs used in chemotherapy, such as eflornithine, work in different ways to stop tumor cells from dividing so they stop growing or die. Androgens can stimulate the growth of pro...
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as goserelin and leuprolide may fight prostate cancer by stopping the adrenal glands from producing andro...
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Drugs used in immunotherapy such as rituximab can locate cancer cel...
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as nilutamide, bicalutamide, flutamide, or cyproterone may stop the adrenal glands from producing androge...
Pyroxamide in Treating Patients With Advanced Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of pyroxamide in...
This is a 48-week study to collect additional information on the safety, tolerability, pharmacokinetics, and antiviral activity of an investigational regimen (course of therapy) including...
Ketoconazole and Docetaxel in Treating Patients With Metastatic Prostate Cancer
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as ketoconazole may stop the adrenal glands from producing androgens. Drugs used in chemotherapy use diff...
PubMed Articles
TL-118-anti-angiogenic treatment in pancreatic cancer: a case report.
Pancreatic cancer is one of the most aggressive malignant tumors. In recent years, little progress has been made in understanding and treatment of the disease. The two most commonly used chemotherapy...
Tuberculosis (TB) disease is treated in most cases with a regimen of several drugs taken for 6-9 months. Currently, 10 drugs are approved by the Food and Drug Administration (FDA) for treatment of TB....
Tetrahydrobiopterin Biosynthesis as an Off-Target of Sulfa Drugs.
The introduction of sulfa drugs for the chemotherapy of bacterial infections in 1935 revolutionized medicine. Although their mechanism of action is understood, the molecular bases for most of their si...
Supramolecular complexations of natural products.
Complexations of natural products with synthetic receptors as well as the use of natural products as host compounds are reviewed, with an emphasis on possible practical uses or on biomedical significa...
The HMG-CoA reductase inhibitors are a class of drugs also known as statins. These drugs are effective and widely prescribed for the treatment of hypercholesterolemia and prevention of cardiovascular...
Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients.
Ginkgo biloba is among the most favourite and best explored herbal drugs. Standardized extracts of Ginkgo biloba represent the only herbal alternative to synthetic antidementia drugs in the therapy of...
In Vitro Assessment of NSAIDs-Membrane Interactions: Significance for Pharmacological Actions.
PURPOSE: To study interactions between nonsteroidal anti-inflammatory drugs (NSAIDs) and membrane mimetic models. METHODS: The interactions of indomethacin and nimesulide with liposomes of dipalmitoyl...
Nitroimidazoles are a class of veterinary drugs used for the treatment and prevention of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle. Sinc...
Drawing on qualitative interview accounts with people who have injected drugs, we deploy ideas of biological and therapeutic citizenship to explore how the negotiation of access to hepatitis C treatme...
We report a study of re-equilibrium kinetics of an oppositely charged hydrogel-surfactant system (cationically modified hydroxyethyl cellulose (cat-HEC) and sodium dodecyl sulfate (SDS)) and an applic...
Videos
Palantir Pharma for R&D, Part I: modeling biological relationships to evaluate drug development risk
The Palantir Gotham data fusion platform helps pharmaceutical companies overcome significant R&D knowledge management challenges by integrating public and pr...
Medical and Biotech [MESH] Definitions
Cinnamomum Aromaticum
A plant species of the genus CINNAMOMUM that contains CINNAMATES and has been used in traditional Chinese medicine (DRUGS, CHINESE HERBAL).
Epimedium
A plant genus of the family BERBERIDACEAE which is used in DRUGS, CHINESE HERBAL. Members contain flavonol glycosides including epimedins, icariin and noricariin.
Cuscuta
A plant genus of the family Cuscutaceae. It is a threadlike climbing parasitic plant that is used in DRUGS, CHINESE HERBAL.
Histamine H1 Antagonists, Non-sedating
A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.
Herb-drug Interactions
The effect of herbs, other PLANTS, or PLANT EXTRACTS on the activity, metabolism, or toxicity of drugs.
