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Pituitary - Biotech, Pharma and Life Science Channel

05:23 EDT 20th June 2013 | BioPortfolio

PubMed Articles [ 1150 Associated PubMed Articles listed on BioPortfolio]

Macular pathology as a cause of visual impairment?

This article reports a case of a pituitary adenoma as the cause of unilateral visual impairment and concomitant unilateral macular pathology. Pituitary adenomas can be classified into hormone-secretin...

Characterization and seasonal changes in LHβ and FSHβ mRNA of Rhinella arenarum (Amphibia, Anura).

In anurans, two types of gonadotropins were described in several species of Ranidae and Pipidae families but only in one of the Bufonidae family. Rhinella arenarum is a bufonid that have the lowest co...

Effects of non-steroidal anti-inflammatory drugs on hormones and genes of the hypothalamic-pituitary-gonad axis, and reproduction of zebrafish.

This study was conducted in two experiments, to identify non-steroidal anti-inflammatory drugs (NSAIDs) with high endocrine disruption potentials, and to understand consequences of exposure to such NS...

Expression of kisspeptins and their Receptors, gnrh-1/gnrhr-II-1a and gonadotropin genes in the brain of adult male and female European sea bass during different gonadal stages.

Kisspeptins play a critical role in the control of hypothalamic-gonadotropic function and puberty onset in mammals. Studies in fish have all supported the hypothesis that they might play similar roles...

The effect of vasopressin 1b receptor (V1bR) blockade on HPA axis activity in rats exposed to acute heat stress.

Thermal stressors such as low and high ambient temperature elicit an abundance of neuroendocrine responses including activation of the hypothalamo-pituitary-adrenal (HPA) axis and arginine vasopressin...

Variation in sequences and mRNA expression levels of growth hormone (GH), insulin-like growth factor I (IGF-I) and II (IGF-II) genes between prolific Lezhi black goat and non-prolific Tibetan goat (Capra hircus).

Growth hormone (GH), insulin-like growth factor-I (IGF-I), and II (IGF-II) play a key role in the development of preantral to preovulatory follicles in some species. To better understand the role of t...

Granulosa cell tumor mutant FOXL2(C134W) suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cells.

A single somatic FOXL2 mutation (FOXL2(C134W)) was identified in almost all granulosa cell tumor (GCT) patients. In the pituitary, FOXL2 and Smad3 coordinately regulate activin stimulation of follista...

Signal transduction involved in GnRH2-stimulation of identified LH-producing gonadotropes from lhb-GFP transgenic medaka (Oryzias latipes).

We have characterized the response to gonadotropin-releasing hormone 2 (GnRH2) in luteinizing hormone producing cells from gfp-transgenic medaka. Teleosts have separate cells producing the two types o...

Male prolactinomas presenting with normal testosterone levels.

In men harboring prolactinoma the most common symptoms are related to hypogonadism, including decreased libido, erectile dysfunction, and gynecomastia. These men characteristically present with elevat...

Increased carotid intima media thickness is associated with prolactin levels in subjects with untreated prolactinoma: a pilot study.

Hyperprolactinemia is associated with endothelial dysfunction and atherogenic risk factors, but carotid intima media thickness (IMT) has not been studied in hyperprolactinemic patients. To determine w...

News Articles [ 107 Associated News Articles listed on BioPortfolio]

Nurse Practitioners in Frenzy Over "Youth Hormone"

NEW YORK, June 20, 2013 /PRNewswire/ -- While it may seem surprising, the topic of "Youth Hormone" therapy is stealing the show at yet another academic conference. Apparently, the professionals a...

"Miracle" Breast Cancer Drug and "Youth Hormone" Pill Steal Show at Prestigious Endocrine Society Conference

SAN FRANCISCO, June 19, 2013 /PRNewswire/ -- It may seem like an odd pairing: an oral growth hormone-boosting supplement and possible cure for breast cancer. But these were two of the most talked...

Patients Honor Dr. Todd Darmody, MD for Compassion

FORT LAUDERDALE, Fla., June 14, 2013 /PRNewswire-USNewswire/ -- Patients' Choice has announced that Dr. Todd Darmody, MD was one of a select few physicians honored with the prestigious 2012 Compassion...

Tübingen Hospital experience with intraoperative MRI improves patient outcomes

VISIUS® Surgical Theatre iMRI brings increased tumor resection and limits patient risks MINNEAPOLIS, MN, June 12, 2013 /PRNewswire/ - IMRIS Inc. (NASDAQ: IMRS; TSX: IM) ("IMRIS" or the "Comp...

"Youth Hormone" Formula SeroVital®-hgh Poised to Steal the Show at Renowned Pituitary Conference

SAN FRANCISCO, June 12, 2013 /PRNewswire/ -- It seems everyone's talking about human growth hormone (hGH) these days. CNN, Fox News, The Today Show, The Dr. Oz Show, Shape magazine… even Va...

Clinical Ascertainment of Health Outcomes Among Adults Treated for Childhood Cancer Outcomes Among Adult Survivors of Childhood Cancer

ImportanceAdult survivors of childhood cancer are known to be at risk for treatment-related adverse health outcomes. A large population of survivors has not been evaluated using a comprehensive system...

Pituitary function: Acute hypocortisolaemia after traumatic brain injury

Discovery Of Possible Key To Cause Of Cushing Disease

Cushing disease is a life-threatening disorder most commonly triggered by tumors, often benign, in the pituitary glands, resulting in excess production of adrenocorticotrophic hormone (ACTH). The cond...

Findings could potentially lead to new drug therapy for Cushing disease

Cushing disease is a life-threatening disorder most commonly triggered by tumors, often benign, in the pituitary glands, resulting in excess production of adrenocorticotrophic hormone.

UCLA-led team may have found key to cause of Cushing disease

(University of California - Los Angeles Health Sciences) UCLA researchers and their colleagues have found that testicular orphan nuclear receptor 4 (TR4) is overexpressed in pituitary tumors that spar...

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Companies [ 2 Associated Companies listed on BioPortfolio]

Vitro Diagnostics, Inc.

Vitro Diagnostics, Inc., dba Vitro Biopharma (OTCBB: VODG) (http://www.vitrobiopharma.com), owns U.S. patents for production of a fertility drug, immortalization of pituitary cell...

Diabetes & Glandular Disease Clinic of San Antonio

The Diabetes & Glandular Disease Clinic, P.A. (DGD) offers the best in treatment for hormonal and metabolic disorders such as type 1 and 2 diabetes, gestational diabetes, thyroid disease, osteoporosis...

Clinical Trials [ 106 Associated Clinical Trials listed on BioPortfolio]

Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion

This study will evaluate whether the drug mifepristone can improve the symptoms of Cushing's syndrome in people with ectopic adrenal corticotrophin hormone (ACTH) secretion. Cushing's synd...

Characterization of Receptors in Non-functioning Pituitary Macroadenomas

Characterization of receptors present in non-functioning pituitary macroadenomas by Reverse Transcriptase- Polymerase Chain Reaction (RT-PCR) would assist with targeted medical therapy bas...

Mediators of Abnormal Reproductive Function in Obesity (MARO)

The study is seeking to understand how being overweight and obese makes women less fertile. The studies the investigators have done so far indicate that there is a hormone or other substan...

Adrenal Function in Critical Illness

An appropriate hypothalamic-pituitary-adrenal (HPA) axis response is required to survive critical illness. Primary adrenal insufficiency, relative adrenal insufficiency, tissue resistance...

Consequence of Lifetime Isolated Growth Hormone Deficiency

Growth hormone (GH) deficiency (GHD) in adulthood has been associated with changes in body composition (e.g. increased abdominal obesity, and reduced muscle mass), in organ functions (e.g....

Growth Hormone Administration and Its Effects on Cardiovascular Risk Factors in Growth Hormone Deficient Women

The purpose of the study is to evaluate the effects of growth hormone replacement on women with growth hormone deficiency. Growth hormone deficiency means the body no longer produces growt...

Evaluation and Treatment of Neurosurgical Disorders

This study offers evaluation and treatment of patients with a variety of neurological disorders that may require surgery. The protocol is not designed to test new treatments; rather, pati...

Study of Thyrotropin-Releasing Hormone in Normal Volunteers and in Patients With Thyroid or Pituitary Abnormalities

This study will determine the safety and activity of a new formulation of thyrotropin-releasing hormone (TRH), a drug used for diagnosing and evaluating patients with certain thyroid gland...

Brain Receptor Function in Post-Traumatic Stress Disorder

The purpose of this study is to examine the function of cortisol receptors in post-traumatic stress disorder (PTSD). Patients with PTSD have neurobiological dysregulation of the hypothala...

Long Term Post Operative Follow-Up of Cushing Syndrome

Although most patients with hypercortisolism can be diagnosed and treated the long-term effects of hypercortisolism and its treatment are unknown. This study will attempt to answer the fo...

Medical and Biotech [MESH] Definitions

Follicle Stimulating Hormone, Human

A major gonadotropin secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and the LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. The alpha subunit is common in the three human pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.

Laron Syndrome

An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.

Pituitary Acth Hypersecretion

A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.

Growth Hormone-secreting Pituitary Adenoma

A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.

Acth-secreting Pituitary Adenoma

A pituitary adenoma which secretes ADRENOCORTICOTROPIN, leading to CUSHING DISEASE.

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