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Plasma Factors - Biotech, Pharma and Life Science Channel

21:33 EDT 20th May 2013 | BioPortfolio

PubMed Articles [ 9983 Associated PubMed Articles listed on BioPortfolio]

Factors influencing the willingness of US women to vaccinate their daughters against the human papillomavirus to prevent cervical cancer.

The human papillomavirus (HPV) vaccine helps to prevent cervical cancer. However, research indicates that public acceptance of the vaccine is suboptimal. Our aims were to evaluate the willingness of U...

Proof of concept studies to confirm the delivery of curcumin loaded solid lipid nanoparticles (C-SLNs) to brain.

Having achieved a significant bioavailability of curcumin by its incorporation into SLNs (C-SLNs) during pharmacokinetic (32-155 times) and pharmacodynamic (3-4 times) studies, our intent was to proof...

The effect of the extract of Crocus sativus on tracheal responsiveness and plasma levels of IL-4, IFN-γ, total NO and nitrite in ovalbumin sensitized Guinea-pigs.

ETHNOMEDICAL RELEVANCE: Anti-inflammatory, anti oxidant and effect of Crocus sativus (C. sativus) on Th1/Th2 balance were described previously.

Effects of Hominis placenta on LPS-induced cell toxicity in BV2 microglial cells.

ETHONOPHARMACOLOGICAL RELEVANCE: Hominis placenta (HP) dried placenta extracted from pregnant women after delivery has been widely used to treat chronic inflammatory diseases. HP has been reported to...

The association of unwanted drug effects and increased psychovegetative lability.

OBJECTIVE: Based on a history of unwanted drug effects, patients had to undergo a series of exposure tests to identify alternative non-invasive drugs. In our study we examined if psychosomatic factors...

Pathogenesis of spinal cord injuries and mechanisms of repair induced by olfactory ensheathing cells.

INTRODUCTION. Spinal cord injury is a catastrophic event with permanent consequences during the all life. Treatment research has been based in the development of therapies that reduce the discapacity,...

Healthcare management of an epilepsy clinic: factors involved in the demand for health care and clinical situation of patients.

INTRODUCTION. Epilepsy is a chronic illness that requires a long-term periodic follow-up of the patient and this means that as time goes by the number of patients attended increases, with the ensuing...

Pharmacokinetic and Pharmacodynamic Interaction of Nadolol With Itraconazole, Rifampicin and Grapefruit Juice in Healthy Volunteers.

To evaluate effects of itraconazole, rifampicin and grapefruit juice on pharmacokinetics and pharmacodynamics of a hydrophilic non-selective β-adrenoceptor blocker nadolol, we conducted an open-label...

Bioequivalence of Eslicarbazepine Acetate from Two Different Sources of its Active Product Ingredient in Healthy Subjects.

PURPOSE: To compare the bioavailability (BA) and pharmacokinetic (PK) properties and to demonstrate the bioequivalence (BE) between two active product ingredient (API) sources of eslicarbazepine aceta...

Clinical Pharmacology of Axitinib.

Axitinib is a potent and selective second-generation inhibitor of vascular endothelial growth factor receptors 1, 2, and 3 that is approved in the US and several other countries for treatment of patie...

News Articles [ 2980 Associated News Articles listed on BioPortfolio]

Sports Medicine New Frontiers: Platelet-Rich-Plasma (PRP) and Stem Cell Therapy

CLEARWATER, Fla., May 20, 2013 /PRNewswire/ -- Sports Medicine is always at the forefront of innovative medical technology.  Athletes are constantly striving to improve. Records are broken as hum...

Elcelyx Therapeutics Enrolling Phase 2b Trial of NewMet for Type 2 Diabetes

SAN DIEGO, May 20, 2013 /PRNewswire/ -- Enrollment of patients with Type 2 diabetes is underway in Elcelyx Therapeutics' Phase 2b dose-finding clinical trial of product candidate NewMet™, a dela...

Childhood ADHD Linked to Obesity in Adults for First Time

New research shows a link between ADHD in children and subsequent obesity in adulthood, suggesting key psychological factors may underlie both this disorder and abnormal eating patterns. Medscap...

South African Markets - Factors to watch on May 20

The following company announcements, scheduled economic indicators, debt and currency market moves and political events may affect South African markets on Monday.

German stocks - Factors to watch on May 20

FRANKFURT, May 20 (Reuters) - The following are some of the factors that may move German stocks on Monday:

More objective testing may reduce cost and risk of managing GERD, study suggests

There are significant cost and risk factors associated with two procedures commonly used to diagnose or treat gastrointestinal problems, according to research presented at Digestive Disease Week.

Singapore Stocks - Factors to watch on May 20

Following are some company-related and market news which could have an impact on the local market. --------------------MARKET SNAPSHOT @ 0002 GMT--------- INSTRUMENT LAST PCT CHG NET CHG S&P 500 1667....

Leading researchers report on the elusive search for biomarkers in Huntington's disease

(IOS Press) The success of HD research depends upon the identification of reliable and sensitive biomarkers to track disease and evaluate therapies, and these biomarkers may eventually be used as outc...

Genetic diversity within tumors predicts outcome in head and neck cancer

(Massachusetts General Hospital) A new measure of the heterogeneity -- the variety of genetic mutations -- of cells within a tumor appears to predict treatment outcomes of patients with the most commo...

New study suggests candy consumption frequency not linked to obesity or heart disease

(FoodMinds LLC) According to a recent data analysis published in the April 30th issue of Nutrition Journal, adults who consume candy at least every other day are no more likely to be overweight nor ha...

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Companies [ 50 Associated Companies listed on BioPortfolio]

Patient Access Solutions, Inc.

Certain statements in this news release may contain forward-looking information within the meaning of Rule 175 under the Securities Act of 1933 and Rule 3b-6 under the Securities...

Hycult Biotech Inc.

Hycult Biotech is a leader in the fields of immunology and cell biology, we develop, produce and market antibodies, antibody based products and more specifically immunoassays for...

Virdante Pharmaceuticals

Virdante Pharmaceuticals is developing safer and more effective drugs for autoimmune and inflammatory diseases. Our products incorporate a proprietary “Sialic Switch” te...

Inova Software Inc.

Inova Software, Inc. is the leading innovation software solutions provider. Our full range of products helps you source, enrich and manage innovative ideas through a software platform. Thus your com...

Ximedica

Ximedica provides integrated research, product development, regulatory and new product introduction services to the world’s leading medical device and consumer healthcare com...

Proteostasis Therapeutics and Elan Corporation

Proteostasis Therapeutics is developing “Proteostasis Regulators” (PRs), small molecule drugs that restore proper protein function or remove misfolded and aggregated pro...

Panasonic Solutions Company

Panasonic Solutions Company empowers people whose jobs depend on reliable technology. The company delivers collaboration, information-sharing and decision-support solutions for cu...

RF IDeas, Inc.

RF IDeas, founded in 1995, is the innovator of WaveID®, the new standard for badge-based authentication and identification solutions powered by RF IDeas readers. Under the Wave...

Gallup-Healthways Well-Being Index

Healthways (NASDAQ:HWAY) is the leading provider of specialized, comprehensive solutions to help millions of people maintain or improve their health and well-being and, as a resul...

Nordson MARCH

Nordson MARCH is the global leader in plasma processing technology for the semiconductor, printed circuit board (PCB), microelectronics, and medical & life science d...

Clinical Trials [ 1941 Associated Clinical Trials listed on BioPortfolio]

Immune Response to Hepatitis C Virus

This study will identify and characterize immune factors involved in hepatitis C infection and elimination of the virus. Individual responses to hepatitis C infection vary; some people ar...

Left Atrial Appendage Occlusion Study II

A pilot, multicentre randomized controlled study of surgical left atrial occlusion (LAA) in 50 patients with atrial fibrillation/flutter undergoing cardiac surgery requiring cardiopulmonar...

Factors Associated With in Suboptimal Prescribing for Older Patients With Epilepsy

Nearly 2% of veterans >65 are actively treated for epilepsy, and the incidence is projected to increase with the aging of our society. Since commonly used antiepileptic drugs are considere...

The Impact of Genotype on Plasma and Cerebral Spinal Fluid Pharmacokinetics of Celecoxib in Children

Background: Celecoxib is effective for reducing postoperative pain in adults. Children use celecoxib more rapidly than adults and require higher doses. Celecoxib is partially metabolized...

TMC435-TiDP16-C112 - Interaction Trial With Antidepressants

The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 150mg q.d. (once a day) on the steady-state pharmacokinetics of escitalopram 10 mg q.d., and...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010 AM1)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls

Scleroderma is an autoimmune disease of unknown origin. Recently, the role of environmental factors, and particularly toxic drug exposure, in the genesis of scleroderma has been suggested....

Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)

Helicobacter pylori (Hp) is a major cause of chronic-active gastritis and primary duodenal ulcers, and is strongly linked to gastric cancer. Most Hp infections worldwide are acquired in c...

Rhythm Disturbances After Ventricular Septal Defects

We would like to conduct a retrospective chart review examining the incidence of surgical heart block in children treated in the Cardiac Service Line at Children’s Healthcare of Atlanta....

The Survey About Resting Metabolic Rate and Its Related Factors in Terminal Patients

According to data from the Taiwanese government, cancer mortality has been the leading cause of death in Taiwan since 1982. The trend is increasing day by day. As the people are aging in T...

Medical and Biotech [MESH] Definitions

Immunity, Herd

The non-susceptibility to infection of a large group of individuals in a population. A variety of factors can be responsible for herd immunity and this gives rise to the different definitions used in the literature. Most commonly, herd immunity refers to the case when, if most of the population is immune, infection of a single individual will not cause an epidemic. Also, in such immunized populations, susceptible individuals are not likely to become infected. Herd immunity can also refer to the case when unprotected individuals fail to contract a disease because the infecting organism has been banished from the population.

Hyperuricemia

Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.

Ovulation Inhibition

Blocking the process leading to OVULATION. Various factors are known to inhibit ovulation, such as neuroendocrine, psychological, and pharmacological agents.

Integration Host Factors

Bacterial proteins that are used by BACTERIOPHAGES to incorporate their DNA into the DNA of the "host" bacteria. They are DNA-binding proteins that function in genetic recombination as well as in transcriptional and translational regulation.

Transcription Factors, General

Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be localized to distinct sequence and structural motifs within the DNA they are considered non-specific with regard to the specific gene being transcribed.

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