Pneumococcal Vaccines - Biotech, Pharma and Life Science Channel
PubMed Articles
Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium.
The transcytosis of antigens across the gut epithelium by microfold cells (M cells) is important for the induction of efficient immune responses to some mucosal antigens in Peyer's patches. Recently,...
During the first decade of the twentieth century, the German bacteriologist Fred Neufeld, later Director of the Robert Koch-Institute in Berlin, first described the differentiation of pneumococci into...
BACKGROUND: High rates of bacterial coinfection in autopsy data from the 2009 H1N1 influenza ("flu") pandemic suggest synergies between flu and pneumococcal disease (PD) during pandemic conditions, an...
Granulocyte-macrophage colony-stimulating factor (GM-CSF) secreting cellular tumor vaccines contribute to the induction of potent antitumor immune responses in murine models and patients suffering fro...
Invasive pneumococcal disease (IPD) has a high mortality. Although preventive strategies including vaccination have been established for children, less attention has been devoted to pregnant and postn...
Using a capillary isoelectric focusing-whole column imaging detection (CIEF-WCID) method the isoelectric points (pI) of complete intact polioviruses were determined. The polio viruses that were analyz...
Cancer immunotherapies, their safety and toxicity.
Introduction: Cancer immunotherapy encompasses a wide range of treatment modalities that harness the anti-tumor effects of the immune system. Some immunotherapies broadly activate the immune system wh...
Designing CAF-adjuvanted dry powder vaccines: Spray drying preserves the adjuvant activity of CAF01.
Dry powder vaccine formulations are highly attractive due to improved storage stability and the possibility for particle engineering, as compared to liquid formulations. However, a prerequisite for fo...
This report summarizes recommendations approved on February 21, 2013, by the Advisory Committee on Immunization Practices (ACIP) for the use of influenza vaccines. An expanded 2013 ACIP influenza vacc...
The 2009 swine-origin H1N1 influenza, though antigenically novel to the population at the time, was antigenically similar to the 1918 H1N1 pandemic influenza, and consequently was considered to be "ar...
News Articles
50 percent of Australians who oppose vaccination get their information from the Internet
To coincide with the broadcast of Jabbed: Love, Fear and Vaccines (SBS ONE, Sunday 26 May at 8.30pm) the first ever national survey on Australian attitudes to vaccination reveals surprising statistics...
Pfizer takes its shot at a vaccine for evasive superbug
CHICAGO (Reuters) - Kathrin Jansen is a microbiologist with at least two breakthrough vaccines to her name: she brought the cervical cancer vaccine Gardasil to market for Merck and helped develop the...
FEATURE-Pfizer takes its shot at a vaccine for evasive superbug
CHICAGO, May 23 (Reuters) - Kathrin Jansen is a microbiologist with at least two breakthrough vaccines to her name: she brought the cervical cancer vaccine Gardasil to market for Merck and helped deve...
Rick King, VP at IAVI, to Present on HIV Vaccine Design at GTC’s Vaccines Conf., July 8-10, Boston
Boston, MA, May 23, 2013 --(PR.com)-- Rick King, Vice President of Vaccine Design at the International Aids Vaccine Initiative, will present on “New Approaches to HIV Vaccine Design” at G...
William Florence, DTRA, to Present on Biodefense Vaccines at GTC’s Vaccines Conf., July 8-10, Boston
Boston, MA, May 23, 2013 --(PR.com)-- William Florence, Acting Branch Chief for Vaccines in the Translational Medical Division at the Defense Threat Reduction Agency, will present on “Current B...
Step Toward Universal Flu Vaccine Shows Promise In Animal Tests
A new approach for creating immunity against the flu virus that produces a stronger immune reaction and protects against more strains than the current vaccines, has shown promising results in animal...
Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies
Influenza viruses pose a significant threat to the public and are a burden on global health systems. Each year, influenza vaccines must be rapidly produced to match circulating viruses, a process cons...
Scientists make important step forward in the quest to develop universal influenza vaccine
A new approach for immunizing against influenza elicited a more potent immune response and broader protection than the currently licensed seasonal influenza vaccines when tested in mice and ferrets.
New microsphere-based methods for detecting HIV antibodies
(Mary Ann Liebert, Inc./Genetic Engineering News) Detection of HIV antibodies is used to diagnose HIV infection and monitor trials of experimental HIV/AIDS vaccines. New, more sensitive detection syst...
Pertussis Vaccines: Whole-Cell More Durable Than Acellular
The risk of contracting pertussis was 6 times higher in teenagers who received 4 acellular pertussis vaccines than teenagers who received 4 whole-cell pertussis vaccines. Medscape Medical News
Events
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Companies
Zoetis (zÅ-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on a 60-year history as the animal health business...
Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, a...
Xenetic is a leading UK-based biopharmaceutical company providing leading-edge expertise in the development of a whole new generation of drugs and vaccines. Working with some of the largest pharma...
VGTI Florida is the Florida-funded expansion of Oregon Health & Science University's highly successful Vaccine and Gene Therapy Institute. Research at the facility will focus on v...
Etubics Corporation, based in Seattle, Wash., is a clinical stage bio-pharmaceutical company, which has developed a proprietary platform technology consisting of a next generation...
Fraunhofer USA CMB, a division of Fraunhofer USA, Inc., is a not-for-profit research organization whose mission is to develop safe and effective vaccines targeting infectious dise...
Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...
Genocea Biosciences is a vaccine discovery and development company targeting major infectious diseases with high unmet medical needs, in which T cell response helps confer protect...
Advaxis is a biotechnology company developing proprietary, live but attenuated Listeria monocytogenes (Listeria) vaccines that deliver engineered tumor antigens, which stimulate...
Genocea Biosciences is a vaccine discovery and development company targeting major infectious diseases with high unmet medical needs, in which T cell responses help confer protect...
Clinical Trials
RATIONALE: Vaccines made from a person's white blood cells may help the body build an effective immune response. PURPOSE: This phase I trial is studying the side effects of vaccine therap...
Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy
Background: - Drugs given to treat cancer (chemotherapy) can weaken the human immune system. But it can also become weaker because of aging. Interleukin (IL)-7, a molecule produced natura...
We plan to study whether the 7-valent pneumococcal conjugate vaccine (Prevnar™) is safe and effective in protecting children who have had a solid organ transplantation and healthy childr...
GSK Biologicals is developing in partnership with the Malaria Vaccine Initiative at PATH a candidate malaria vaccine RTS,S/AS02 for the routine immunization of infants and children living...
A Study to Assess the Safety of Live Intranasal Sendai Virus Vaccine in Children and Toddlers
Croup is an illness of young children that is caused by a virus. With this illness, the child has fever, cough, and hoarseness. Although the illness usually gets better in 2 to 4 days, so...
Vitamin A Supplementation With Routine Childhood Vaccines and Mortality and Morbidity
Vitamin A supplementation (VAS) is important for the immune system and may interact with different childhood vaccinations. We have hypothesized that the improved survival after VAS may dep...
The purpose of this study is to learn whether or not giving a tetanus/diphtheria vaccination ("tetanus shot") before giving pneumococcal vaccine makes the pneumococcal vaccine more effecti...
Prevention of Respiratory Infections and MAnagement Among Children (PRIMAKid)
The PRIMAKid trial is a general practice based double-blind randomized placebo-controlled trial on the effectiveness and costs of combined influenza and pneumococcal vaccination in pre-sch...
MMR and Varicella Vaccine in Premature Infants
This research is designed to address the question, "Does the relative deficit in vaccine immunogenicity in extremely premature infants persist beyond the first 6 months of life?" We propos...
Study to Eliminate Hib Carriage in Rural Alaska Native Villages
Hib disease rates in rural Alaska before introduction of HIb conjugate vaccine were among the highest in the world. Since vaccine introduction, rates have fallen by 90% but the disease ha...
Videos
Pneumococcal Vaccines for Developing Countries
Having witnessed the enormous impact of a vaccine that essentially eradicated meningitis due to Haemophilus influenza type b (Hib) in the United States, Dr. ...
Medical and Biotech [MESH] Definitions
Tuberculosis Vaccines
Vaccines or candidate vaccines used to prevent or treat TUBERCULOSIS.
Ebola Vaccines
Vaccines or candidate vaccines used to prevent EBOLA HEMORRHAGIC FEVER.
Dengue Vaccines
Vaccines or candidate vaccines used to prevent infection with DENGUE VIRUS. These include live-attenuated, subunit, DNA, and inactivated vaccines.
West Nile Virus Vaccines
Vaccines or candidate vaccines used to prevent infection with WEST NILE VIRUS.
Electrochemotherapy
A treatment modality that uses pulsed electrical currents to permeabilize cell membranes (ELECTROPORATION) and thereby enhance the uptake of chemotherapeutic agents, vaccines, or genes into the body's cells.