Postoperative hepatitis - Biotech, Pharma and Life Science Channel

12:05 EDT 22nd May 2015 | BioPortfolio

PubMed Articles [3560 Associated PubMed Articles listed on BioPortfolio]

Drug Use, Hepatitis C, and Service Availability: Perspectives of Incarcerated Rural Women.

This study examined drug use, hepatitis C, and service availability and use among a high-risk sample of rural women serving time in jails. Data was collected from female offenders (N = 22) who parti...

Cancer of the Oral Cavity.

Cancer of the oral cavity is one of the most common malignancies worldwide. Although early diagnosis is relatively easy, presentation with advanced disease is not uncommon. The standard of care is pri...

Determining need for treatment in residual pituitary adenomas.

The optimal management of residual pituitary adenoma after resection is not clearly defined, with some authors proposing early radiosurgery or radiotherapy for patients with evidence of residual tumor...

Periodontal and peri-implant wound healing following laser therapy.

Laser irradiation has numerous favorable characteristics, such as ablation or vaporization, hemostasis, biostimulation (photobiomodulation) and microbial inhibition and destruction, which induce vario...

Pre-clinical in vivo models for the screening of bone biomaterials for oral/craniofacial indications: focus on small-animal models.

Preclinical in vivo experimental studies are performed for evaluating proof-of-principle concepts, safety and possible unwanted reactions of candidate bone biomaterials before proceeding to clinical t...

Tumor size is not a criterion for resection during the management of giant hemangioma of the liver.

Liver hemangiomas are the most common benign liver tumors. The management of giant (≥5 cm) hemangioma of the liver remains controversial. The aim of this study was to assess the influence of tumor...

Fulminant presentation of autoimmune hepatitis: clinical features and early predictors of corticosteroid treatment failure.

Classical features of autoimmune hepatitis (AIH) may be altered during the abrupt onset of the disease. Corticosteroid therapy can be life-saving, but its use in the fulminant presentation of AIH (F-A...

Nonsurgical Management and Postoperative Rehabilitation of Medial Instability of the Knee.

The medial ligaments of the knee are the most frequently injured structures of the knee joint. The decisions regarding the treatment of medial knee injuries must take into account the severity of inju...

Management of Chronic Combined PCL Medial Posteromedial Instability of the Knee.

Currently, there is no collective consensus on the most effective treatment method for medial collateral ligament injuries with or without associated structural deficiencies. An in-depth understanding...

Autoimmune Colitis and Subsequent CMV-induced Hepatitis After Treatment With Ipilimumab.

Ipilimumab, a humanized CTLA-4 antibody, improves overall survival in patients with metastatic melanoma. However, immune-related adverse effects occur in about 65% of ipilimumab-treated patients and h...

News Articles [1437 Associated News Articles listed on BioPortfolio]

Patient Risk Model Can Help Target Costly HCV Treatment to Those With Most Urgent Need

A team of researchers at the University of Michigan Health System has developed a risk prediction model that helps identify which hepatitis C patients have the most urgent need for new antiviral drugs...

Japan prices Sovaldi well below US

Japan has granted a reimbursement price to Gilead Sciences' hepatitis C drug Sovaldi (sofosbuvir) as the first all-oral therapy for the disease in the country, with each pill priced well below US lev...

Janssen, Achillion Pharmaceuticals Team Up to Fight Hepatitis C

Janssen Pharmaceuticals, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced that it has entered into an exclusive worldwide license and collaboration arrangement with Ach...

Omidria® Receives Positive Opinion from European Medicines Agency's Committee for Medicinal Products for Human Use

SEATTLE, May 22, 2015 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER), a biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeuti...

Japan Prices Sovaldi Well Below U.S.

Japan has granted a reimbursement price to Gilead's hepatitis C drug Sovaldi as the first all-oral therapy for the disease in the country, with each pill priced well below U.S. levels but still set to...

Ledipasvir plus sofosbuvir: Hint of added benefit in further patient group

(Institute for Quality and Efficiency in Health Care) The documents subsequently submitted by the manufacturer show an advantage in sustained virologic response also for hepatitis C infection of genot...

Celiac Disease Lowers Hepatitis B Vaccine Response

In children with celiac disease, immunologic response to the hepatitis B vaccine is impaired, even after a gluten-free diet or a booster, new research shows. Medscape Medical News

Achillion Shares Sink after Partnering with Johnson & Johnson

Investors started shedding Achillion shares early Wednesday, less than a day after the drugmaker announced a partnership with pharmaceutical giant Johnson & Johnson that snuffed out the prospect ...

US Senator dubs Sovaldi price ‘abuse of power’ and calls to defy patent

US Senator Bernie Sanders has called on the Secretary of Veteran Affairs to invoke a law which would break Gilead’s patent on Hepatitis C drug Sovaldi and allow cheaper generics.

Activists challenge Gilead to give up Hep C drug patent

Biospectrum I-AMK has challenged Gilead for seeking illegitimate patents for hepatitis C medicine sofosbuvir [Read more...

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Companies [27 Associated Companies listed on BioPortfolio]

Primrose Healthcare

Primrose Healthcare is dedicated to leading the healthcare industry in delivering the most advanced technology and evidence-based care protocols available for the optimized treatm...

Vaxart, Inc.

Vaxart is a privately owned company developing oral recombinant vaccines based on its proprietary delivery platform. The Vaxart platform is suitable to deliver any protein vaccine...

Advanced Biological Laboratories

Advanced Biological Laboratories (ABL), S.A., is a Medical Data Technology company founded in 2000 as a spin-off from CRP-Santé Luxembourg. ABL took control of TherapyEdge, Inc...

Ichor Medical Systems, Inc.

Ichor Medical Systems’ TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. I...

Transgene SA

Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...

AbbVie

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the exp...

Okairos

Okairos is a clinical-stage biopharmaceutical company, developing genetic vaccines for major infectious diseases - including malaria, hepatitis C, influenza, respiratory syncytial...

Profectus BioSciences, Inc.

Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...

Viropro

Viropro Inc. (“Viropro”) operates through Viropro International Inc., a Canadian company with its Head Office in Montreal. Viropro International Inc. is specialized in the technology transfer, fo...

Enanta Pharmaceuticals, Inc.

Enanta Phatmaceuticals ARE A RESEARCH AND DEVELOPMENT-FOCUSED BIOTECHNOLOGY COMPANY that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs in t...

Clinical Trials [2089 Associated Clinical Trials listed on BioPortfolio]

Transient Elastography in Autoimmune Hepatitis

Recent, research has focused on the evaluation of non-invasive methods for the assessment of liver fibrosis in patients with chronic liver disease. Among these methods, transient elastogra...

Effect of Morphine, Tramadol, and Ketorolac on Postoperative Stress and Immune Responses

Comparison between the effects of intravenous morphine, tramadol and ketorolac on stress and immune responses in patients undergoing modified radical mastectomy

Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants

In order to assess whether the bivalent killed oral cholera vaccine may be used safely among infants who are most at risk for cholera, the investigators need to determine the safety and im...

UNITY 3: A Japanese Phase 3 Study of a Daclatasvir/Asunaprevir/BMS-791325 in Subjects With Genotype 1 Chronic Hepatitis C

The purpose of this study is to demonstrate that the proportion of treatment-naive non-cirrhotic subjects with Genotype (GT)-1b treated with Daclatasvir (DCV)/Asunaprevir (ASV)/BMS-791325 ...

Combined Intrathecal Morphine and Dexmedetomidine Analgesia

The current study investigated the effect of adding dexmedetomidine to intrathecal morphine for postoperative analgesia in cancer patients undergoing major abdominal surgery.

A Randomized, Open-Label Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir Co-administered With Ribavirin (RBV) in Adults With Genotype 4 Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis (AGATE-1)

The purpose of this study in HCV genotype 4-infected subjects with compensated cirrhosis is to assess the safety and to compare the percentage of subjects achieving a 12-week sustained vir...

Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients

This Phase 1b trial will assess the dose-related safety and PK profile of different doses of NVR 3-778 in patients with chronic hepatitis B. Additionally,changes in patients' serum HBV DN...

Staged Phase I/II Hepatitis C Prophylactic Vaccine

Phase I/II, double-blinded, randomized, placebo-controlled study of HCV-uninfected male and female active IDU aged 18 to 45 years. In Stage I 68 (+/-4) evaluable subjects will be enrolled ...

A Study to Evaluate the Efficacy and Safety of Three Experimental Drugs Compared With Telaprevir (a Licensed Product) for Treatment of Chronic Hepatitis C Infection in Treatment-experienced Adults

This is a study to evaluate the efficacy and safety of three experimental drugs compared with Telaprevir (a licensed product) in people with hepatitis C virus infection who have been previ...

Intra-Peritoneal Local Anaesthesia After Cytoreductive Surgery

Can perioperative administration of intra-peritoneal local anaesthetics further reduce postoperative pain, inflammation and outcome in patients undergoing major abdominal surgery (cytoredu...

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Medical and Biotech [MESH] Definitions

INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).

A family of hepatotropic DNA viruses which contains double-stranded DNA genomes and causes hepatitis in humans and animals. There are two genera: AVIHEPADNAVIRUS and ORTHOHEPADNAVIRUS. Hepadnaviruses include HEPATITIS B VIRUS, duck hepatitis B virus (HEPATITIS B VIRUS, DUCK), heron hepatitis B virus, ground squirrel hepatitis virus, and woodchuck hepatitis B virus (HEPATITIS B VIRUS, WOODCHUCK).

A species in the genus HEPATOVIRUS containing one serotype and two strains: HUMAN HEPATITIS A VIRUS and Simian hepatitis A virus causing hepatitis in humans (HEPATITIS A) and primates, respectively.

INFLAMMATION of the LIVER in humans caused by HEPATITIS DELTA VIRUS, a defective RNA virus that can only infect HEPATITIS B patients. For its viral coating, hepatitis delta virus requires the HEPATITIS B SURFACE ANTIGENS produced by these patients. Hepatitis D can occur either concomitantly with (coinfection) or subsequent to (superinfection) hepatitis B infection. Similar to hepatitis B, it is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.

INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.

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