Postoperative hepatitis - Biotech, Pharma and Life Science Channel

00:12 EST 24th November 2014 | BioPortfolio

PubMed Articles [3761 Associated PubMed Articles listed on BioPortfolio]

Successful treatment of rectovaginal fistula complicating ulcerative colitis with infliximab: a case report and review of the literature.

Rectovaginal fistula is a rare complication of ulcerative colitis (UC) regardless of surgical history of rectum. Various surgical treatment modalities for the closure of rectovaginal fistula have been...

Spontaneous postpartum rupture of an intact uterus: a case report.

Rupture of uterus is an obstetrical complication characterized by a breach in the uterine wall and the overlying serosa. We report an unusual case of spontaneous rupture of an unscarred uterus in a 33...

Investigating the relationship between persistent reflux flow on the first postoperative day and recurrent varicocele in varicocelectomy patients.

The aim of this study was to investigate the presence of persistent reflux flow on the first postoperative day using color Doppler sonography (CDS) in patients who had undergone sub-inguinal varicocel...

Anesthetic considerations on adrenal gland surgery.

Adrenal gland surgery needs a multidisciplinary team including endocrinologist, radiologist, anesthesiologist, and surgeon. The indications for adrenal gland surgery include hormonal secreting and non...

The 2014 consensus guidelines for the management of postoperative nausea and vomiting: A leapfrog towards a postoperative nausea and vomiting-free hospital.

Relationship between HCV dynamics and sustained virological responses in chronic hepatitis C genotype 1b patients treated with telaprevir-based triple therapy.

This study investigated the relationship between hepatitis C virus (HCV) dynamics and sustained virological response (SVR), as well as the efficacy of an extended treatment with telaprevir-based tripl...

Acute Health Care Resource Utilization for Ileostomy Patients Is Higher Than Expected.

Patients requiring an ileostomy following colorectal surgery are at risk for increased health-care utilization after discharge. Prior studies evaluating postoperative ileostomy care may underestimate ...

Stimulation of the Efferent Limb Before Ileostomy Closure: A Randomized Clinical Trial.

Postoperative ileus is the most common complication after ileostomy closure with an increase in morbidity, hospital stay, and health care costs.

Incidence of virological failure and emergence of resistance with twice-daily vs every 8-h administration of telaprevir in the OPTIMIZE study.

The OPTIMIZE study demonstrated noninferior efficacy between telaprevir (TVR) twice daily (bid) vs every 8-h (q8h) administration. This analysis compared the selective pressure of both dosing regimens...

Combination therapy of interferon and nucleotide/nucleoside analogues for chronic hepatitis B.

Chronic hepatitis B is one of the leading causes of cirrhosis and hepatocellular carcinoma globally. At present, seven drugs, including two interferons and five oral nucleos(t)ide analogues (NAs), hav...

News Articles [1318 Associated News Articles listed on BioPortfolio]

Molecular detection of hepatitis E virus (HEV) in liver biopsies after liver transplantation

EMA unit backs new hep C drugs Exviera and Viekirax from AbbVie

The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended a marketing authorization for US pharma company AbbVie’s Exviera (dasabuvir) and Viekirax (omb...

EMA Panel Backs Exviera, Viekirax for Chronic Hepatitis C

Exviera and Viekirax were recommended by the European Medicines Agency's Committee for Medicinal Products for Human Use for the treatment of adults with chronic hepatitis C. International Approvals

Enanta Pharmaceuticals to Present at the Deutsche Bank 2014 BioFEST

Presentation to be Webcast on December 1 at 10:25 A.M. ET Enanta Pharmaceuticals, Inc., (NASDAQ:ENTA) a research and development-focused biotechnology company dedicated to cre...

Europe gives green light to AbbVie hepatitis C drugs, others

LONDON (Reuters) - European regulators recommended approval for two drugs made by AbbVie to treat hepatitis C, both of which belong to a new generation of medicines that have proved effective in treat...

UPDATE 1-Europe gives green light to AbbVie hepatitis C drugs, others

(Adds further recommendations, additional indication for Otezla)

Enanta Announces CHMP Grants Positive Opinions of AbbVie's VIEKIRAX (ombitasvir/paritaprevir(ABT-450)/ritonavir) + EXVIERA (dasabuvir) for the Treatment of Chronic Hepatitis C in Europe

Final decision from the European Commission expected in the first quarter of 2015 Enanta Pharmaceuticals, Inc., (NASDAQ: ENTA) a research and development-focused biotechnology company dedicated to...

Enanta Announces CHMP Grants Positive Opinions of AbbVie’s VIEKIRAX™ (ombitasvir/paritaprevir(ABT-450)/ritonavir) + EXVIERA™ (dasabuvir) for the Treatment of Chronic Hepatitis C in Europe

Final decision from the European Commission expected in the first quarter of 2015 Enanta Pharmaceuticals, Inc., (NASDAQ: ENTA) a research and developm...

CHMP Grants Positive Opinions of AbbVie's VIEKIRAX' (ombitasvir/paritaprevir/ritonavir) + EXVIERA' (dasabuvir) for the Treatment of Chronic Hepatitis C in Europe

- Major regulatory milestone achieved toward approval in the European Union - Final decision from the European Commission expected in the first quarter of 2015 NORTH CHICAGO, Illinois, Nov. 21, 20...

France negotiates lowest price in Europe for Gilead’s Sovaldi

The discount negotiated by the French government on hepatitis C drug Sovaldi (sofosbuvir), produced by US biotech major Gilead Sciences, makes it the ‘lowest price in Europe,’ according to the cou...

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Companies [27 Associated Companies listed on BioPortfolio]

Primrose Healthcare

Primrose Healthcare is dedicated to leading the healthcare industry in delivering the most advanced technology and evidence-based care protocols available for the optimized treatm...

Vaxart, Inc.

Vaxart is a privately owned company developing oral recombinant vaccines based on its proprietary delivery platform. The Vaxart platform is suitable to deliver any protein vaccine...

Advanced Biological Laboratories

Advanced Biological Laboratories (ABL), S.A., is a Medical Data Technology company founded in 2000 as a spin-off from CRP-Santé Luxembourg. ABL took control of TherapyEdge, Inc...

Ichor Medical Systems, Inc.

Ichor Medical Systems’ TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. I...

Transgene SA

Transgene (NYSE-Euronext: TNG), a member of the Institut Mérieux Group, is a biopharmaceutical company. It creates, develops and manufactures targeted immunotherapeutics for th...

AbbVie

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the exp...

Okairos

Okairos is a clinical-stage biopharmaceutical company, developing genetic vaccines for major infectious diseases - including malaria, hepatitis C, influenza, respiratory syncytial...

Profectus BioSciences, Inc.

Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...

Viropro

Viropro Inc. (“Viropro”) operates through Viropro International Inc., a Canadian company with its Head Office in Montreal. Viropro International Inc. is specialized in the technology transfer, fo...

Enanta Pharmaceuticals, Inc.

Enanta Phatmaceuticals ARE A RESEARCH AND DEVELOPMENT-FOCUSED BIOTECHNOLOGY COMPANY that uses its robust chemistry-driven approach and drug discovery capabilities to create small molecule drugs in t...

Clinical Trials [1880 Associated Clinical Trials listed on BioPortfolio]

HBsAg Decline After Pegylated-interferon-α in e Antigen Positive Chronic Hepatitis B With Nucleoside Maintenance

This study proposes to compare the effect of 48 weeks exposure to pegylated interferon alpha vs. nucleoside analogue (NA) on hepatitis B e antigen (HBeAg) seroconversion and HBsAg levels ...

Ondansetron's Opposite Effect on Postoperative Analgesia of Acetaminophen

The purpose of the study is to determine whether the effect of ondansetron on the analgesic effect of acetaminophen. Because 5HT3 blockers prevent the analgesic effects of acetaminophen an...

Comparison of the Effects of Neostigmine With Sugammadex on Postoperative Nausea and Vomiting.

Postoperative nausea and vomiting is one of most common complications after general anesthesia. Female sex, history of postoperative nausea and vomiting, motion sickness, non smoker status...

Study of PEG-Intron Plus REBETOL in Pediatric Subjects With Chronic Hepatitis C (Study P02538 Part 1)

The primary objective is to assess the safety, efficacy and tolerability of the combination of PEG-Intron plus REBETOL in pediatric subjects with chronic hepatitis C. The secondary objecti...

A Follow-Up Study of Patients With HBeAg Positive Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML22265

This multicenter, prospective, observational study will evaluate the one-year ou tcomes in HBeAg positive chronic hepatitis B patients who had received Pegasys ( peginterferon alfa-2a) in ...

Evaluating the Effectiveness of Boceprevir, Pegylated-Interferon Alfa 2b and Ribavirin in Treating Hepatitis C Virus (HCV) Infection in Adults With HIV and HCV Infection

Hepatitis C virus (HCV) infection is a leading cause of death and illness in people with HIV-1. Currently, the standard treatment for people with HIV-1 and HCV coinfection includes two dru...

An Observational Study of Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C

This prospective observational study will investigate predictive values of virol ogical response in peginterferon/ribavirin treatment-naive patients with chronic hepatitis C. Patients will...

Study of Efficacy and Safety of Grazoprevir (MK-5172)/Elbasvir (MK-8742) Combination Regimen for Treatment-Naïve Participants With Chronic Hepatitis C Virus Genotypes 1, 4, and 6 (MK-5172-060)

This is an efficacy and safety study of grazoprevir (MK-5172) in combination with elbasvir (MK-8742) in treatment-naive participants with chronic hepatitis C virus (HCV) genotype (GT) 1, 4...

The Effect of Fluid Management by SVV of FloTrac/ Vigileo™ Monitoring on Postoperative Recovery in Bowel Resection Laparotomy

During an enterectomy, especially in an open surgery, large amounts of fluid are administered in consideration of the patient's fasted state, maintaining blood pressure during surgery and ...

Grazoprevir (MK-5172) and Elbasvir (MK-8742) Combination for Chronic Hepatitis C Virus (HCV) Genotypes 1, 4, and 6 (MK-5172-065)

This is a randomized, multi-site, placebo-controlled trial of a fixed dose combination (FDC) of grazoprevir (MK-5172) 100 mg + elbasvir (MK-8742) 50 mg in participants with chronic Hepatit...

Medical and Biotech [MESH] Definitions

INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).

A family of hepatotropic DNA viruses which contains double-stranded DNA genomes and causes hepatitis in humans and animals. There are two genera: AVIHEPADNAVIRUS and ORTHOHEPADNAVIRUS. Hepadnaviruses include HEPATITIS B VIRUS, duck hepatitis B virus (HEPATITIS B VIRUS, DUCK), heron hepatitis B virus, ground squirrel hepatitis virus, and woodchuck hepatitis B virus (HEPATITIS B VIRUS, WOODCHUCK).

A species in the genus HEPATOVIRUS containing one serotype and two strains: HUMAN HEPATITIS A VIRUS and Simian hepatitis A virus causing hepatitis in humans (HEPATITIS A) and primates, respectively.

INFLAMMATION of the LIVER in humans caused by HEPATITIS DELTA VIRUS, a defective RNA virus that can only infect HEPATITIS B patients. For its viral coating, hepatitis delta virus requires the HEPATITIS B SURFACE ANTIGENS produced by these patients. Hepatitis D can occur either concomitantly with (coinfection) or subsequent to (superinfection) hepatitis B infection. Similar to hepatitis B, it is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.

INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.

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