Posttraumatic seizures - Biotech, Pharma and Life Science Channel
PubMed Articles
Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy.
Objective: Epigenetic mechanisms involved in transcriptional regulation of multiple molecular pathways are potentially attractive therapeutic interventions for epilepsy, since single target therapies...
The negative impact of single prolonged stress (SPS) on bone development in mice.
Abstract Posttraumatic stress disorder (PTSD) disrupts hypothalamic-pituitary-adrenal (HPA) axis function. Given the established role of HPA axis hormones in regulating bone metabolism, we tested the...
INTRODUCTION. Epilepsy is a chronic illness that requires a long-term periodic follow-up of the patient and this means that as time goes by the number of patients attended increases, with the ensuing...
Expanding the phenotype of IQSEC2 mutations: truncating mutations in severe intellectual disability.
Intellectual disability (ID) is frequent in the general population, with 1 in 50 individuals directly affected worldwide. The multiple etiologies include X-linked ID (XLID). Among syndromic XLID, few...
BACKGROUND: Acetabular fractures are rare in children and can be complicated by premature fusion of the triradiate cartilage resulting in secondary acetabular dysplasia. Early recognition and treatmen...
This study examined the neuropsychological performance of 125 outpatient Operation Enduring Freedom/Operation Iraqi Freedom combat veterans with posttraumatic stress disorder (PTSD) and nonacute mild...
Child Neurology: Zellweger syndrome.
Zellweger syndrome (ZS) is a severe manifestation of disease within the spectrum of peroxisome biogenesis disorders that includes neonatal adrenoleukodystrophy, infantile Refsum disease, and rhizomeli...
In the past, the cortex has for the most part been considered to be the site of seizure origin in the different forms of epilepsy. Findings from histopathologic, electrophysiologic, and brain imaging...
Endocannabinoids and their attending cannabinoid type 1 (CB1) receptor have been implicated in animal models of post-traumatic stress disorder (PTSD). However, their specific role has not been studied...
News Articles
Diazepam Addiction Treatment and Prescription Drug Rehab Center Announced
Diazepam Addiction Treatment and Drug Rehab Announced by Recovery Associates, Offering Treatment for Those Addicted to Diazepam. WEST PALM BEACH, Fla. (PRWEB) May 21, 2013 Recovery Associates, throug...
Epilepsy Foundation Elects New Board Of Directors And Chairman
LANDOVER, Md., May 20, 2013 /PRNewswire-USNewswire/ -- The Epilepsy Foundation, a national organization dedicated to serving all people with seizures, today announced the election of its first of...
Insero Health Reports Positive Data on Phase I Trial of Novel Therapy for Drug-resistant Epilepsy
MIAMI, May 17, 2013 /PRNewswire/ -- Insero Health, Inc., a company developing natural compounds to address unmet medical needs in epilepsy and related neurological disorders, is today repo...
MIAMI, May 17, 2013 /PRNewswire-USNewswire/ -- The Epilepsy Foundation today announced the 2013 winner of the Epilepsy Therapy Project Second Annual "Shark Tank" competition for the most i...
New Stem Cell Growth Strategy Could Yield Better Way to Treat Brain Lesions
In a study just published in STEM CELLS Translational Medicine, researchers have found a new way to increase the survival of stem cells injected into the brain. The discovery might one day prove usefu...
Posttraumatic stress disorder associated with type 2 diabetes
The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the Univers...
Link Between Epilepsy And Autism Found
Adults with epilepsy are more likely to have a greater number of characteristics of autism and Asperger syndrome, according to new research by the University of Bath, England. The finding was discover...
Research discovers link between epilepsy and autism
(Medical Xpress)—University of Bath researchers have found a previously undiscovered link between epileptic seizures and the signs of autism in adults.
People suffering from PTSD have risk of developing type 2 diabetes
The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the Univers...
Neuroscience: Cell transplants stem seizures
Stem-cell therapy can reduce seizures in epileptic mice.Some forms of epilepsy are thought to be caused by dysfunctional cells in the hippocampus region of the brain. The affected cells, called inhibi...
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Companies
Epilepsy Foundation of Georgia
The Epilepsy Foundation, a national nonprofit with affiliated organizations throughout the United States, has lead the fight since 1968 to stop seizures, find a cure and overcome...
Clinical Trials
To evaluate the efficacy and safety of Vanquix for the management of selected, refractory, patients with epilepsy who require intermittent medical intervention provided by caregivers who a...
This is a Non-interventional Prospective Study. Centres will enroll adult patients with partial-onset seizures with or without secondary generalisation for whom the clinician has decided t...
The purpose of this study is to determine if a drug called topiramate is safe and effective as an add-on therapy in the treatment of Obsessive-Compulsive Disorder (OCD). Topiramate is an...
Comparing Virtual Reality Therapy to Usual Treatment for PTSD
Combat related Posttraumatic Stress Disorder (PTSD) is the most common chronic psychiatric disorder in the veteran population. Unfortunately, outcome studies of VA PTSD programs have fa...
Patients with focal epileptic seizures with or without generalization who are at present treated with one or two antiepileptic drugs are eligible for this study, provided that they fulfill...
Open Label Safety and Efficacy Study of Levetiracetam in Patients With Epilepsy
Community based study assessing safety and efficacy of levetiracetam in partial onset seizures. The optimal dose in daily clinical practice will be used.
An open-label, follow-up study to evaluate the safety and efficacy of levetiracetam (LEV), in children (≥ 4 years old), adolescents and adults suffering from primary generalized seizure...
Cohorts and Collections: Clinical and Genetic Study of Parkinson's Disease and Epilepsies
The DNA and Cell Bank of Instituts Federatifs de Recherche (IFR) of Neurosciences has been running for the last 15 years at the Institut National de la Santé Et de la Recherche Médicale...
Male and female patients between 16 and 70 years of age who are diagnosed with epilepsy with partial seizures and are taking up to 3 medications for this medical condition will take part i...
Mantram Repetition to Manage PTSD in Veterans
With ongoing war in Iraq, the incidence of posttraumatic stress disorder (PTSD) in combat veterans is increasing. Creation, implementation, and testing of new and innovative interventions...
Videos
Seizures and Post-Traumatic Stress Disorder (complex, chronic, PTSD)
Eye sight problems that I had through the period of two years - just like in this video, only I had more than one of those and they would move around. http:/...
Medical and Biotech [MESH] Definitions
Persistent Hyperinsulinemia Hypoglycemia Of Infancy
A form of nontransient HYPOGLYCEMIA, unique to infancy, due to autosomal recessive mutations of the sulfonylurea receptor gene on CHROMOSOME 11. Defects in the sulfonylurea receptors (ATP-BINDING CASSETTE TRANSPORTERS) on the PANCREATIC BETA CELLS prevent negative feedback of GLUCOSE-regulated INSULIN release thus resulting in HYPERINSULINEMIA. Clinical phenotype includes SEIZURES; COMA; and often large BIRTH WEIGHT for GESTATIONAL AGE.
Hypertension, Pregnancy-induced
A condition in pregnant women with elevated systolic (>140 mm Hg) and diastolic (>90 mm Hg) blood pressure on at least two occasions 6 h apart. HYPERTENSION complicates 8-10% of all pregnancies, generally after 20 weeks of gestation. Gestational hypertension can be divided into several broad categories according to the complexity and associated symptoms, such as EDEMA; PROTEINURIA; SEIZURES; abnormalities in BLOOD COAGULATION and liver functions.
Tay-sachs Disease, Ab Variant
A progressive neurodegenerative disorder that begins with muscle weakness, then progresses to startle reaction, retardation and seizures. It is characterized by the accumulation of G(M2) GANGLIOSIDE in neurons that is caused by a lack of G(M2) ACTIVATOR PROTEIN function. The AB variant designation refers to the increase of both HEXOSAMINIDASE A and HEXOSAMINIDASE B in tissues that lack of G(M2) activator protein.
Transcranial Magnetic Stimulation
A technique that involves the use of electrical coils on the head to generate a brief magnetic field which reaches the CEREBRAL CORTEX. It is coupled with ELECTROMYOGRAPHY response detection to assess cortical excitability by the threshold required to induce MOTOR EVOKED POTENTIALS. This method is also used for BRAIN MAPPING, to study NEUROPHYSIOLOGY, and as a substitute for ELECTROCONVULSIVE THERAPY for treating DEPRESSION. Induction of SEIZURES limits its clinical usage.
Posterior Leukoencephalopathy Syndrome
A condition that is characterized by HEADACHE; SEIZURES; and visual loss with edema in the posterior aspects of the CEREBRAL HEMISPHERES, such as the BRAIN STEM. Generally, lesions involve the white matter (nerve fibers) but occasionally the grey matter (nerve cell bodies).
