Prenatal Genetic Counseling and Evaluation - Biotech, Pharma and Life Science Channel
PubMed Articles
The influence of genetic polymorphisms in MDR1 gene on breast cancer risk factors in Chinese.
Breast cancer (BC) is the most common cancer among women in the world. The human multidrug resistance 1 gene (MDR1) is potentially an important gene influencing the susceptibility to breast cancer. Th...
The association of genetic polymorphisms related to metabolism of homocysteine and folate with inflammatory bowel disease has been evidenced. Several studies have identified genetic variants of MTHFR...
Tagging SNPs in the ERCC4 gene are associated with gastric cancer risk.
ERCC4 plays an essential role in the nucleotide excision repair (NER) pathway, which is involved in the removal of a wide variety of DNA lesions. To determine whether the ERCC4 tagging SNPs (tSNPs) ar...
A novel mutation in the SLCO2A1 gene in a Chinese family with primary hypertrophic osteoarthropathy.
Primary hypertrophic osteoarthropathy (PHO) is a rare monogenetic disease that closely mimics hypertrophic osteoarthropathy secondary to pulmonary or other pathology. The study of PHO provides an oppo...
Genetic analysis of candidate SNPs for metabolic syndrome in obstructive sleep apnea (OSA).
Obstructive sleep apnea (OSA) is a common disorder characterized by the reduction or complete cessation in airflow resulting from an obstruction of the upper airway. Several studies have observed an i...
Hearing loss is one of the most common sensory disorders in humans and has a genetic cause in 50% of the cases. Our recent studies indicate that nonsyndromic hearing loss (NSHL) in the Saudi Arabian p...
Ischemic stroke is a multifactorial disease leading to severe long-term disability and it is the third leading cause of death in developed countries. Although many studies have been reported to elucid...
Congenital hyperinsulinism: Clinical and molecular analysis of a large Italian cohort.
Congenital hyperinsulinism (CHI) is a genetic disorder characterized by profound hypoglycemia related to an inappropriate insulin secretion. It is a heterogeneous disease classified into two major sub...
Assessment of GE food safety using '-omics' techniques and long-term animal feeding studies.
Despite the fact that a thorough, lengthy and costly evaluation of genetically engineered (GE) crop plants (including compositional analysis and toxicological tests) is imposed before marketing some E...
Health status of cardiac genetic disease patients and their at-risk relatives.
Health status is an important outcome measure that incorporates multiple dimensions of health, including symptoms, functional status, and psychosocial factors. While health status has been shown to be...
News Articles
Netherlands first to approve new fixed-dose combination treatment for men with lower urinary tract symptoms associated with BPH ASTELLAS PHARMA EUROPE B.V., the European subsidiary of Tokyo-based Aste...
The Genetic Basis Of Six Autoimmune Diseases Investigated By Researchers
Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases. The exact cause of these d...
Marketing to the big data inside us
A Minneapolis-based startup called Miinome plans to build what it calls the first “member-controlled human genetic marketplace.” The company, which has just three full-time employees and is stil...
Diabetes’ genetic underpinnings can vary based on ethinic background, studies say
Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine. (Medical...
Infantile myofibromatosis: First drug targets in childhood genetic tumor disorder
Two mutations central to the development of infantile myofibromatosis (IM) -- a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic target...
Genetically modified purple tomato 'tastier than normal varieties'
The UK Telly carries a tastefully good storyA genetically modified purple tomato that is tastier than normal varieties and can last for more than a month before going off has been invented by scientis...
Study Shows Eating Junk Food While Pregnant May Increase Likelihood of Childhood Obesity
Recent studies have shown that eating junk food during pregnancy can have lasting effects on your child. Liquid Health suggests a healthy diet and a high quality-prenatal vitamin to get all the essen...
Companies
Vitals (www.vitals.com), an innovative, online doctor evaluation and comparison service from MDX Medical Inc., is a comprehensive source for crucial information, peer evaluations and patient feedback...
With the advent of new technologies, in the last four years, DNA sequencing has gone through a technological revolution which has completely changed the market. While in 2007 it still cost over 10 m...
Interleukin Genetics, Inc. (OTCQB: ILIU) develops and markets a line of genetic tests under the Inherent Health® brand. The products empower individuals to prevent ce...
Founded in 2010 and based in Atlanta, curavita coordinates clinical care for critically injured workers. Through early intervention, a proprietary national network of catastrophic...
Lineagen (www.lineagen.com) is a provider of diagnostic and healthcare services focused on complex diseases for which individualsâ genetic profiles contribute strongly to...
NovaSom, Inc. is a privately held diagnostic-service provider for home testing and evaluation of sleep-disordered breathing, which includes the diagnosis of obstructive sleep apne...
Cascade Technologies Corp., through its wholly-owned subsidiary Spectral Molecular Imaging, Inc. (SMI), is a development-stage medical imaging device company, applying its proprie...
AseraCare Hospice is part of Golden Living, one of the nationâs premiere providers of health care services for the aging. AseraCare Hospice offers a full range of hospice and...
Cascade Technologies Corporation
Cascade Technologies Corp., through its wholly owned subsidiary Spectral Molecular Imaging, Inc., is a development-stage, medical imaging device company, applying its proprietary...
The Go Daddy Group, Inc. and Southwest Center for HIV/AIDS
Southwest Centerâs mission is to lead the fight against HIV/AIDS by preventing the disease, by improving the quality of life for those who are impacted, and by contributing t...
Clinical Trials
The goal of this study is to compare the effects of exercise with the effects of relaxation training on physical function (how well participants perform normal daily activities) and sympto...
Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection
The primary focus of the study is the evaluation of the safety of treatment with moxifloxacin in a pediatric population 3 months to
CBT for Social Anxiety Disorder Delivered by School Counselors
This 5-year study addresses the unmet needs of adolescents with social phobia through the testing of a 12-week cognitive-behavioral, school-based group intervention delivered by trained sc...
Marinobufagenin as a Target for DIGIBIND in Preeclampsia
Background: - Preeclampsia is a combination of high blood pressure and other potentially life-threatening symptoms. Preeclampsia occurs in up to 10% of pregnancies and is a...
Gene Expression in Cumulus Cells to Predict Pregnancy
The purpose of this study is to determine the performance of a genetic assay, GemART, in cumulus cells predictive of embryo viability, and pregnancy success in women undergoing in vitro fe...
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not rece...
New Media Obesity Treatment in Community Health Centers
This purpose of this trial is to determine whether a 12-month eHealth behavioral intervention that includes interactive self-monitoring and feedback, tailored skills training materials, te...
Family Preparation Study For Withdrawal of Mechanical Ventilation From Their Family Member
Using the self-regulation theory, an intervention to prepare families for that experience was developed. This study will assess the impact of the intervention on a family’s evaluation of...
Low cobalamin (vitamin B12) levels are frequent in the elderly. Most often they reflect a mild metabolic abnormality without clinical symptoms (subclinical cobalamin deficiency). It is unc...
A Pilot Study of the Neural Correlates of Treatment Effect on Nicotine Craving
The purpose of this study is to gather pilot data to determine feasibility of and guide the development of a larger clinical trial investigating the effects of topiramate as an adjunct to...
Videos
Prenatal Heart Diagnosis
At the Center for Prenatal Pediatrics, pregnancy involves caring for two patients mother and baby. In high-risk cases where the baby has a birth defect, the ...
Medical and Biotech [MESH] Definitions
Dna Shuffling
The use of DNA recombination (RECOMBINATION, GENETIC) to prepare a large gene library of novel, chimeric genes from a population of randomly fragmented DNA from related gene sequences.
Embryo Research
Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus during the prenatal stage of development that is characterized by rapid morphological changes and the differentiation of basic structures. In humans, this includes the period from the time of fertilization to the end of the eighth week after fertilization.
Heterogeneous-nuclear Ribonucleoprotein K
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Micrornas
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
Directive Counseling
Counseling during which a professional plays an active role in a client's or patient's decision making by offering advice, guidance, and/or recommendations.
