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Preoperative Evaluation - Biotech, Pharma and Life Science Channel

15:43 EDT 19th June 2013 | BioPortfolio

PubMed Articles [ 4691 Associated PubMed Articles listed on BioPortfolio]

The role of systemic inflammatory and nutritional blood-borne markers in predicting response to neoadjuvant chemotherapy and survival in oesophagogastric cancer.

The aim of this study was to interrogate whether blood-borne inflammatory and nutritional markers predict long-term survival and response to neoadjuvant chemotherapy in radically treated oesophagogast...

Prophylaxis and management of complications in penetrating keratoplasty.

Besides routine postoperative follow-up the prophylaxis of complications in penetrating keratoplasty (PKP) includes special preoperative and intraoperative aspects. Preoperative prophylaxis consists o...

Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1).

Using structure-based drug design, we identified and optimized a novel series of pyrimidodiazepinone PLK1 inhibitors resulting in the selection of the development candidate TAK-960. TAK-960 is current...

Evaluation of bioactivities of chlorokojic acid derivatives against dermatophytes couplet with cytotoxicity.

In an attempt to find novel antifungal agents with improved activity, a series of compounds bearing 6-chloromethyl-3-hydroxy-2-substituted 4H-pyran-4-one moiety were synthesized and examined for their...

Synthesis and preliminary evaluation steroidal antiestrogen-geldanamycin conjugates.

Three novel steroidal antiestrogen-geldanamycin conjugates were prepared using a convergent strategy. The antiestrogenic component utilized the 11β-(4-functionalized-oxyphenyl) estradiol scaffold, wh...

Agreement between medical record and parent report for evaluation of childhood febrile seizures.

The monitoring of vaccine safety is critical to maintaining the public acceptance of vaccines required to ensure their continued success. Methods used to assess adverse events following immunization (...

Karnofsky Performance Status predicts overall survival, cancer-specific survival, and progression-free survival following radical cystectomy for urothelial carcinoma.

OBJECTIVE: Radical cystectomy (RC) can provide a survival advantage in patients with urothelial carcinoma of the bladder, but not without significant morbidity rates. Whether the ability of preoperati...

Preoperative predictors for allogenic blood transfusion in hip and knee arthroplasty for rheumatoid arthritis.

INTRODUCTION: To identify the preoperative predictors of requirement for postoperative allogenic blood transfusion following hip and knee joint arthroplasty. MATERIALS AND METHODS: We analysed the ret...

Sleeve gastrectomy or gastric bypass as revisional bariatric procedures: retrospective evaluation of outcomes.

BACKGROUND: A considerable number of patients require revisional surgery after laparoscopic adjustable gastric banding (LAGB). Studies that compared the outcomes of revisional sleeve gastrectomy (r-SG...

A semi-automated tool for treatment plan-quality evaluation and clinical trial quality assurance.

The goal of this work is to develop a plan-quality evaluation program for clinical routine and multi-institutional clinical trials so that the overall evaluation efficiency is improved. In multi-insti...

News Articles [ 1132 Associated News Articles listed on BioPortfolio]

Renowned Regulatory Representatives From Mainland China and Taiwan to Discuss Need for Collaboration at DIA Meeting

Discussion between two centers first ever to take place in U.S. Horsham, PA (PRWEB) June 18, 2013 Senior drug regulatory officials from mainland China and Taiwan will be in Boston on June 25 to discu...

The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism

PETA International Science Consortium disappointed in denial of Dow appeal

(People for the Ethical Treatment of Animals) The PETA International Science Consortium is extremely disappointed that the European Chemicals Agency Board of Appeal has upheld a decision that requires...

IDEAL framework for surgical innovation 2: observational studies in the exploration and assessment stages

IntroductionThe evaluation of new innovations, from idea developed to accepted practice, has been less orderly in surgery and other interventional therapies than in clinical pharmacology. The IDEAL......

Japan’s MHLW To Set Up Rapid Evaluation System For Advanced Medical Technology And Pharmaceuticals

Japan’s MHLW plans to introduce a new system, tentatively named the “rapid assessment system for advanced medical care,” to speed up the evaluation of medical technology and pharmaceuticals prod...

Self-Management Of Rheumatoid Arthritis Aided By Nurse-Led Programs

Data first presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism demonstrate the benefits of a nurse-led programme on patient self-management and the management of rhe...

Hand Hygiene Monitoring Technology: Advice for Product Evaluation and Purchasing

Infection Control Today invited manufacturers of automated hand hygiene monitoring systems to provide information that will assist infection preventionists in evaluating and purchasing these technolog...

Political Cartoon: 'No-Go Pogo?'

Kaiser Health News provides a fresh take on health policy developments with "No-Go Pogo?" by Nick Anderson. Meanwhile, here is today's health policy haiku:   PERFORMANCE EVALUATION High-...

The role of OCT4 immunohistochemistry in evaluation of retroperitoneal lymph node dissections: a pilot study

FDA Review Article Provides New Insights into Cancer Immunotherapy Product Development; Beneficial to all Involved in Cancer Treatment

Published in the Journal for ImmunoTherapy of Cancer, review offers recommendations for manufacturing, pre-clinical studies, and clinical trial designs of cancer immunotherapies Milwaukee, WI (PRWEB)...

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Companies [ 41 Associated Companies listed on BioPortfolio]

Cupron Medical Inc.

A private company based in Richmond, Virginia and Herzylia, Israel, Cupron is the developer of proprietary technology that enhances a diverse range of products by incorporating th...

Vitals.com

Vitals (www.vitals.com), an innovative, online doctor evaluation and comparison service from MDX Medical Inc., is a comprehensive source for crucial information, peer evaluations and patient feedback...

curavita

Founded in 2010 and based in Atlanta, curavita coordinates clinical care for critically injured workers. Through early intervention, a proprietary national network of catastrophic...

Lineagen, Inc.

Lineagen (www.lineagen.com) is a provider of diagnostic and healthcare services focused on complex diseases for which individuals’ genetic profiles contribute strongly to...

NovaSom, Inc.

NovaSom, Inc. is a privately held diagnostic-service provider for home testing and evaluation of sleep-disordered breathing, which includes the diagnosis of obstructive sleep apne...

Cascade Technologies Corp.

Cascade Technologies Corp., through its wholly-owned subsidiary Spectral Molecular Imaging, Inc. (SMI), is a development-stage medical imaging device company, applying its proprie...

Cascade Technologies Corporation

Cascade Technologies Corp., through its wholly owned subsidiary Spectral Molecular Imaging, Inc., is a development-stage, medical imaging device company, applying its proprietary...

ABMS

For more than 75 years, the American Board of Medical Specialties (ABMS) has been the medical organization overseeing physician certification in the United States. It assists its...

Drug Safety Executive Council (DSEC)

CHA is the leading organizer of consortia in life sciences. CHA reduces the costs of R&D by bringing companies together to work cooperatively. The Technology Evaluation Consortium...

Theracrine, Inc.

Theracrine is a private biopharmaceutical company dedicated to the discovery and development of novel therapeutics in the emerging field of cancer spread. To drive these efforts,...

Clinical Trials [ 869 Associated Clinical Trials listed on BioPortfolio]

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

The primary focus of the study is the evaluation of the safety of treatment with moxifloxacin in a pediatric population 3 months to

Marinobufagenin as a Target for DIGIBIND in Preeclampsia

Background: - Preeclampsia is a combination of high blood pressure and other potentially life-threatening symptoms. Preeclampsia occurs in up to 10% of pregnancies and is a...

Family Preparation Study For Withdrawal of Mechanical Ventilation From Their Family Member

Using the self-regulation theory, an intervention to prepare families for that experience was developed. This study will assess the impact of the intervention on a family’s evaluation of...

Glutamine and Intestinal Protein Metabolism

Gut barrier plays a major role in defence of the organism. During catabolic states, like major surgery or inflammation, gut barrier could be altered. It has been reported that preoperative...

Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly

Low cobalamin (vitamin B12) levels are frequent in the elderly. Most often they reflect a mild metabolic abnormality without clinical symptoms (subclinical cobalamin deficiency). It is unc...

Pilot Study to Evaluate the Restore Orthobiologic Implant in Rotator Cuff Tear Repair

Primary Endpoints: Comparative evaluation of any differences between the two groups in change from baseline to the 3-month time point in terms of: - Functional recovery (patient...

Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women?

OBJECTIVE: To test the use of two adjunctive hormonal agents in a 28 day three-arm, double-blind, placebo-controlled study in the treatment of acute mania/hypomania. HYPOTHESIS:...

Evaluation of TEACH (Training Early Achievers for Careers in Health) Research

The conceptual framework underlying the TEACH Research Program is based on a specific theoretical approach designed to influence adolescent career choice, in this case towards a career in...

Preoperative or Postoperative Therapy of Patients With Stages IB, II, IIIA Non-Small Cell Lung Cancer

In this phase II study, we plan to evaluate several novel components of therapy. In patients with potentially resectable stages IIB (T3N0) and IIIA we will compare weekly paclitaxel and c...

Preoperative Therapy With Oxaliplatin/Docetaxel/Capecitabine and Radiation in Resectable Esophagus Cancer

In this phase I/II trial, we will evaluate a novel combination of chemotherapy, used concurrently with radiation therapy, in the preoperative therapy of locoregional carcinoma of the esoph...

Medical and Biotech [MESH] Definitions

Whole Body Imaging

The creation of a visual display of the inside of the entire body of a human or animal for the purposes of diagnostic evaluation. This is most commonly achieved by using MAGNETIC RESONANCE IMAGING; or POSITRON EMISSION TOMOGRAPHY.

Clinical Audit

A detailed review and evaluation of selected clinical records by qualified professional personnel to improve the quality of patient care and outcomes. The clinical audit was formally introduced in 1993 into the United Kingdom's National Health Service.

Clinical Alarms

Components of medical instrumentation used for physiological evaluation of patients, that signal when a threshold value is reached.

Diagnostic Test Approval

The process of gaining approval by a government regulatory agency for DIAGNOSTIC REAGENTS AND TEST KITS. This includes any required preclinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance.

Hospital Rapid Response Team

Multidisciplinary team most frequently consisting of INTENSIVE CARE UNIT trained personnel who are available 24 hours per day, 7 days per week for evaluation of patients who develop signs or symptoms of severe clinical deterioration.

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