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Primary osteoporosis - Biotech, Pharma and Life Science Channel

14:34 EDT 21st May 2013 | BioPortfolio

PubMed Articles [ 5878 Associated PubMed Articles listed on BioPortfolio]

Congress Report: 5th Central and Eastern Europe (CEE) Summit on Osteoporosis in Bratislava, 2-3 December 2011.

Major aims of the 5th Central and Eastern Europe (CEE) Summit on Osteoporosis held in Bratislava, Slovakia, on 2 and 3 December 2011, were to provide participants with state-of-the-art knowledge in th...

A health economic analysis of osteoporotic fractures: who carries the burden?

This is a cost-of-illness study of osteoporotic fractures in Denmark estimating the incremental societal cost associated with osteoporotic fractures, with both direct cost and productivity cost. This...

Clinical and economic characteristics of hip fracture patients with and without muscle atrophy/weakness in the United States.

This retrospective analysis of hip fracture patients with and without muscle atrophy/weakness (MAW) revealed that those with MAW had significantly higher healthcare utilization and costs compared with...

Effective treatment of a steroid-induced femoral neck fracture nonunion with a once-weekly administration of teriparatide in a rheumatoid patient: a case report.

INTRODUCTION: Nonunion of femoral neck fractures frequently occurs in elderly patients. In patients with rheumatoid arthritis, reoperation rates after internal fixation of a displaced femoral neck fra...

Intrapartum sacral stress fracture due to pregnancy-related osteoporosis: a case report.

Low back pain (LBP) and hip pain frequently occur during pregnancy and postpartum period. Although pelvic and mechanic lesions of the soft tissues are most responsible for the etiology, sacral fractur...

Incidence of hip fracture in Rohtak district, North India.

Hip fracture incidence is not known in India. This retrospective study was conducted to evaluate hip fracture incidence rates in Rohtak, a single district of North India. A total of 304 patients from...

Efficient synthesis of highly substituted pyrroles through a Pd(OCOCF3)2-catalyzed cascade reaction of 2-alkenal-1,3-dicarbonyl compounds with primary amines.

We describe an unprecedented Pd(OCOCF3)2-catalyzed cascade process for the synthesis of highly functionalized 1,2,3,5-tetrasubstituted pyrroles with high efficiency. Unlike documented methods relying...

Glucose deprivation reversibly down-regulates tissue plasminogen activator via proteasomal degradation in rat primary astrocytes.

Tissue plasminogen activator (tPA) is an essential neuromodulator whose involvement in multiple functions such as synaptic plasticity, cytokine-like immune function and regulation of cell survival man...

Radionuclide parathyroid imaging: a concise, updated review.

The hypercalcemia of hyperparathyroidism (HPT) can cause devastating effects to the patient and only surgical removal of the hyperfunctioning parathyroid tissue can definitely cure the disease. Radion...

Everolimus-eluting bioresorbable vascular scaffold (BVS) implantation in patients with ST-segment elevation myocardial infarction (STEMI).

Aims: Recent studies have demonstrated favourable clinical outcomes for the everolimus-eluting bioresorbable vascular scaffold (BVS) ABSORB™ in patients with stable coronary artery disease. There is...

News Articles [ 3608 Associated News Articles listed on BioPortfolio]

Phase III Trial Of L-BLP25 In Patients With Non-Small Cell Lung Cancer (START) - Primary Endpoint Of Significantly Improving Overall Survival Not Met

Confirmed: Primary endpoint of significantly improving overall survival not met Merck Serono, a division of Merck, Darmstadt, Germany, today announced detailed results from the randomized Phase III ST...

'Doctor shopping' by obese patients negatively affects health

(Johns Hopkins Medicine) Overweight and obese patients are significantly more likely than their normal-weight counterparts to repeatedly switch primary care doctors, a practice that disrupts continuit...

Imaging technique shows premature birth interrupts vital brain development processes leading to reduced cognitive abilities in i

This video shows the development of the frontal and temporal regions of the cerebral cortex in preterm infants during the last three months before the normal time of birth, turning from red to blue...

Biological and Therapeutic Effects of Ortho-Silicic Acid

Silicon in its bioavailable form of ortho-silicic acid may prove to have potential therapeutic effects for a wide variety of conditions, from Alzheimer's disease to osteoporosis. Nutrition and Metab...

KevinMD's Take, May 20, 2013

By Kevin, M.D. One of the more contentious issues in the health care debate is the scope of practice of non-physician providers such as nurse practitioners. According to a New England Journal of Med...

CardioDx unveils positive study results of Corus CAD gene expression test

CardioDx has unveiled the study results of a clinical utility study of the Corus CAD gene expression test in the real-world primary care setting for evaluating patients with signs and symptoms suggest...

Sanofi planning filings on top-line JAKARTA read-out

Top-line results for the Phase III JAKARTA trial of Sanofi's JAK 2 inhibitor SAR302503 have come in positive and on schedule in myelofibrosis. Sanofi says the study met the primary endpoint, which is...

Mechanism linking key inflammatory marker to cancer identified

Researchers have revealed how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor grow...

XenoPort's Arbaclofen placarbil fails to meet co-primary endpoints in Phase 3 clinical trial

XenoPort, Inc. announced today top-line results from its pivotal Phase 3 clinical trial of arbaclofen placarbil for the treatment of patients with spasticity due to multiple sclerosis.

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Companies [ 161 Associated Companies listed on BioPortfolio]

AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialization of prescription medicines. As a leader in gastrointestin...

IDS Ltd

From its establishment in 1977, simply as a Distributor of diagnostic products, IDS has become a globally-recognised innovator and marketeer in the IVD industry.The Company is particularly well-known...

Health Discovery Corporation

Health Discovery Corporation is a molecular diagnostics company that uses advanced mathematical techniques to analyze large amounts of data to uncover patterns that might otherwis...

Eli Lilly and Company

Eli Lilly and Company is a leading, innovation-driven corporation committed to developing a growing portfolio of best-in-class and first-in-class pharmaceutical products that help people live longer...

IPC The Hospitalist Company, Inc.

IPC The Hospitalist Company, Inc. (Nasdaq: IPCM) is a leading physician group practice company focused on the delivery of hospitalist medicine and related facility-based services. IPC's physicians and...

Vitera Healthcare Solutions

Vitera Healthcare Solutions, formerly Sage Healthcare, provides end-to-end clinical and financial technology solutions to more than 400,000 healthcare professionals including 80,0...

Heart Rhythm Society

The Heart Rhythm Society is the international leader in science, education and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorder...

TheAmerican Association of Clinical Endocrinologists (AACE)

The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...

Infant Swimming Resource, LLC

Founded in 1966, Infant Swimming Resource (ISR) is nationally recognized as the safest provider of Self-RescueTM swimming lessons for children 6 months to 6 years of age. With a p...

Capitol Scientific, Inc.

Since its inception in 1963, Capitol Scientific has built a formidable enterprise by leveraging a vast portfolio of name brand products concentrated in high-purity & reagent chemi...

Clinical Trials [ 1122 Associated Clinical Trials listed on BioPortfolio]

Evaluation of M118 in Percutaneous Coronary Intervention (EMINENCE)

The primary objective is to evaluate the safety and feasibility of using M118 as an anticoagulant in the target population of subjects with stable coronary artery disease (CAD) undergoing...

Treatment of Osteopenia With Melatonin

The aim of the study is to assess the effect of melatonin treatment in patients with osteopenia on BMD, muscle function, quality of life and calcium homeostasis.

Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)

This is a Phase III, multicenter, open-label study of RI-002 administered as an intravenous infusion of RI-002 (IGIV) every 21 or 28 days in approximately 60 subjects with Primary Immunode...

New Media Obesity Treatment in Community Health Centers

This purpose of this trial is to determine whether a 12-month eHealth behavioral intervention that includes interactive self-monitoring and feedback, tailored skills training materials, te...

Ticagrelor and Intracoronary Morphine in Patients Undergoing Primary Percutaneous Coronary Intervention

A 2 by 2 factorial, multicenter, prospective, randomized, open-label, blinded endpoint trial. Patients undergoing primary PCI for STEMI will be eligible. Enrolled patients will be randomly...

Risedronate to Prevent Skeletal Related Events in Patients With Metastatic Prostate Cancer Commencing Hormonal Therapy

Risedronate is an orally administered pyridinyl bisphosphonate that is 36 times more potent than pamidronate and 72 times more potent than clodronate. Four randomized, double-blind trials...

Can Screening People Registering With Primary Care Improve the Detection of Tuberculosis?

This randomised controlled trial tests whether screening people registering with general practices cost-effectively increases the detection of tuberculosis. The study objectives are to:...

Primary Care Management/Action Plans for Advanced Chronic Diseases

Patients living with advanced chronic diseases (ACD), such as congestive heart failure (CHF) and chronic obstructive lung disease (COPD) present substantial care and economic challenges fo...

2-Year Therapy With Teriparatide vs 1-yr Therapy Followed by 1-Year of Raloxifene or Calcium/Vit D in Severe Postmenopausal Osteoporosis

The primary purpose of the study is to compare 3 different osteoporosis therapies following one year of teriparatide.In the first year,all eligible patients received open-label teriparatid...

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Liver Transplantation.

To evaluate and to compare efficacy and safety of a dual regimen with oral modified release tacrolimus FK506E (MR4) / steroids versus a dual regimen with oral tacrolimus FK506 / steroids i...

Medical and Biotech [MESH] Definitions

Transcriptional Elongation Factors

Transcription factors whose primary function is to regulate the rate in which RNA is transcribed.

Pubmed

A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.

Mechanotransduction, Cellular

The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.

Leptospira Interrogans Serovar Autumnalis

A serovar of the bacterial species LEPTOSPIRA INTERROGANS, whose primary host is the MOUSE.

Leptospira Interrogans Serovar Icterohaemorrhagiae

A serovar of the bacterial species LEPTOSPIRA INTERROGANS, whose primary host is RATS.

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