Radiation - Biotech, Pharma and Life Science Channel
PubMed Articles
Accelerated hypofractionation (HF) using larger dose per fraction, delivered in fewer fractions over a shorter overall treatment time, is presently a consistent possibility for adjuvant whole breast r...
The accurate detection and dosimetry of neutrons in mixed and pulsed radiation fields is a demanding instrumental issue with great interest both for the industrial and medical communities. In recent s...
Alpha (α) particles and low-energy beta (β) particles present minimal risk for external exposure. While these particles can induce leukemia and bone cancer due to internal exposure, they can also be...
Dosimetry of biological irradiations using radiochromic films.
Delivering accurate radiation dose to blood specimens during biological irradiations is essential in quantifying damage of ionizing radiation. To estimate dose to blood samples as accurately as possib...
In girls and young women, irradiation of the ovaries can reduce the number of viable ovarian primordial follicles, which may lead to premature ovarian failure (POF) and subsequently to sterility. One...
Microdosimetry is a recommended method for characterizing radiation quality in situations when the biological effectiveness under test is not well known. In such situations, the radiation beams are de...
Sodium tungstate modulates ATM function upon DNA damage.
Both radiotherapy and most effective chemotherapeutic agents induce different types of DNA damage. Here we show that tungstate modulates cell response to DNA damaging agents. Cells treated with tungst...
CIZ1, a p21(Cip1/Waf1)-interacting protein, functions as a tumor suppressor in vivo.
CIZ1 is a nuclear protein involved in DNA replication and is also implicated in human diseases including cancers. To gain an insight into its function in vivo, we generated mice lacking Ciz1. Ciz1-def...
BACKGROUND: We investigated nimotuzumab (h-R3), a humanized monoclonal antibody against epidermal growth factor receptor, when combined with irradiation or chemoradiation for squamous cell carcinoma (...
Chronic exposure to solar radiation is the primary cause of photoaging and benign and malignant skin tumors. A conditioned serum-free medium (SFM) was prepared from umbilical cord mesenchymal stem cel...
News Articles
New Pong Technology Smartphone and Tablet Cases Marry Science and Art
Designed by IDEO, the New Cases Provide a Glimpse of the Embedded Pong Antenna That Reduces User Exposure to Wireless Energy and Optimizes Device Performance Pong Resea...
Children Who Have CT Scans May Face Higher Cancer Risk
WEDNESDAY, May 22 (HealthDay News) -- Children and teens exposed to radiation during CT scans are 24 percent more likely to develop cancer, according to a large, long-term study. The risks, however,...
Cleveland BioLabs to Present at Second Annual Marcum LLP Microcap Conference
BUFFALO, N.Y., May 22, 2013 /PRNewswire/ -- Cleveland BioLabs, Inc. (NASDAQ:CBLI) today announced that the Company is scheduled to present at the Second Annual Marcum LLP Microcap Conference, May...
Japan hospital tests powerful breast cancer therapy
A Japanese cancer specialist said Wednesday she has started the world's first clinical trial of a powerful, non-surgical, short-term radiation therapy for breast cancer.
Obesity directly tied to several cancers
"Obesity is a major risk factor for developing cancer, roughly the equivalent of tobacco use, and both are potentially reversible. Further, obese cancer patients do worse in surgery, with radiation or...
Research suggests that IMRT may not be more effective in patients who had prostatectomy
Intensity-modulated radiation therapy has become the most commonly used type of radiation in prostate cancer, but research from the University of North Carolina suggests that the therapy may not be mo...
CT radiation risks coming into clearer focus
Recent attention to the cancer risks of ionizing radiation has prompted vigorous debate about how to quantify the risks of diagnostic imaging, and whether or how these risks ought to be incorporated.....
Objective To assess the cancer risk in children and adolescents following exposure to low dose ionising radiation from diagnostic computed tomography (CT) scans.Design Population based, cohort, data.....
News From Annals Of Internal Medicine, May 21, 2013
1. Older, Sicker Men Unlikely to Benefit from Aggressive Therapy for Newly Diagnosed Prostate Cancer Older men with localized prostate cancer and other serious health conditions may not benefit from a...
Columbia University licenses 3D segmentation software to Varian
Columbia University has signed a licensing agreement with Varian Medical Systems for novel imaging software that facilitates 3D segmentation, the process by which anatomical structures in medical imag...
Events
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Companies
Algeta was founded in 1997 (as Anticancer Therapeutic Inventions) based upon a unique combination of radiation chemistry, nuclear medicine and clinical oncology expertise brought together by its two...
Loma Linda University Medical Center
Loma Linda University Medical Center (LLUMC), a Seventh-Day Adventist institution, is among the largest private medical educational centers in the United States and the only one in inland Southern...
Onconova, based in Newtown, PA and Lawrenceville, NJ, discovers and develops novel patent- protected small molecule therapeutic agents for cancer, radiation protection and hematol...
BSD Medical Corporation develops, manufactures, markets and services systems to treat cancer and benign diseases using heat therapy delivered using focused radio frequency (RF) an...
âWe encourage all citizens to write Congress about the widespread, unchecked, non-stop proliferation of radiofrequency radiation in our midst and the inaction of the FCC to r...
American Semiconductor, Inc. is a complete silicon fabrication source, providing a broad suite of services to enable product realization from concept to fabrication. As an on-shor...
OnCure Holdings, Inc. operates radiation oncology treatment centers for cancer patients. Oncure Medical Corp. (âOncureâ), a wholly-owned subsidiary of OnCure Holdings, I...
America Stem Cell is a privately held biotechnology company based in San Antonio, TX, with offices in San Diego, CA, and is dedicated to the development and commercialization of s...
Radimetrics provides radiation dose monitoring and management software to hospitals and imaging centers. Radimetricsâ flagship product, eXposure⢠is a single-system solu...
Riverain Technologies, formerly Riverain Medical, is a Dayton, Ohio-based medical technology innovator that develops practical solutions to save and improve the quality of people...
Clinical Trials
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Study of Markers of Cosmic Radiation Exposure and Effect Among Flight Crews
Ionizing radiation efficiently induces chromosomal aberrations (CA) and several studies of CA have now been conducted among small groups of flight crews. However, most of the studies only...
The purpose of this study is to determine whether Intensity-modulated radiation therapy (IMRT) combined inductive and concurrent chemotherapy with more intensive regimen (cisplatin and pac...
Our long-term working hypothesis is that if 3-D radiation is combined with the effect of capecitabine one hopes to see improved and durable tumor response and survival with acceptable toxi...
A Phase I Study of Oral Topotecan as a Radiosensitizing Agent in Patients With Rectal Carcinoma
This is an open-label, single center, phase I study designed to determine the MTD or oral topotecan as a radiosensitizing agent in the treatment of rectal cancer patients. Sequential cohor...
RATIONALE: Drugs used in chemotherapy, such as 5-fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing and a...
In this phase II study, we plan to evaluate several novel components of therapy. In patients with potentially resectable stages IIB (T3N0) and IIIA we will compare weekly paclitaxel and c...
In this phase I/II trial, we will evaluate a novel combination of chemotherapy, used concurrently with radiation therapy, in the preoperative therapy of locoregional carcinoma of the esoph...
Pemetrexed Plus Cisplatin Neoadjuvant Therapy Followed By Surgery and Radiation in Mesothelioma
Phase II trial of Neoadjuvant Chemotherapy with Pemetrexed plus Cisplatin followed by Surgery and Radiotherapy in patients with Malignant Pleural Mesothelioma stage I-III. The event-free...
Assessment of Treatment Response Using PET/CT Scanner - Non Hodgkin's Lymphoma
In this study the treatment process will be closely monitored using a novel imaging technology, a PET/CT scanner. PET stands for Positron Emission Tomography and in this case it will be c...
Videos
SimCity: Radiation Rebuild #1
My first commentary. Sorry, I have a terrible audio recorder. Radiation Rebuild series: I rebuild a city after a terrifying nuclear disaster.
Medical and Biotech [MESH] Definitions
Deinococcus
A genus of gram-positive aerobic cocci found in the soil, that is highly resistant to radiation, especially ionizing radiation (RADIATION, IONIZING). Deinococcus radiodurans is the type species.
Virus Inactivation
Inactivation of viruses by non-immune related techniques. They include extremes of pH, HEAT treatment, ultraviolet radiation, IONIZING RADIATION; DESICCATION; ANTISEPTICS; DISINFECTANTS; organic solvents, and DETERGENTS.
Nijmegen Breakage Syndrome
A chromosome instability syndrome resulting from a defective response to DNA double-strand breaks. In addition to characteristic FACIES and MICROCEPHALY, patients have a range of findings including RADIOSENSITIVITY, immunodeficiency, increased cancer risk, and growth retardation. Causative mutations occur in the NBS1 gene, located on human chromosome 8q21. NBS1 codes for nibrin, the key regulator protein of the R/M/N (RAD50/MRE11/NBS1) protein complex which senses and mediates cellular response to DNA DAMAGE caused by IONIZING RADIATION.
Mucositis
An INFLAMMATION of the MUCOSA with burning or tingling sensation. It is characterized by atrophy of the squamous EPITHELIUM, vascular damage, inflammatory infiltration, and ulceration. It usually occurs at the mucous lining of the MOUTH, the GASTROINTESTINAL TRACT or the airway due to chemical irritations, CHEMOTHERAPY, or radiation therapy (RADIOTHERAPY).
Fanconi Anemia Complementation Group D2 Protein
A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.
