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07:08 EDT 25th May 2013 | BioPortfolio

PubMed Articles [ 3648 Associated PubMed Articles listed on BioPortfolio]

A three-drug induction chemotherapy with gemcitabine, carboplatin, and paclitaxel for stage III non-small cell lung cancer.

The aim of the study is to evaluate the efficacy and safety of a three-drug chemotherapy regimen including gemcitabine, carboplatin, and paclitaxel as induction therapy in clinical stage III non-small...

Cardiac remodeling with rhythm versus rate control strategies for atrial fibrillation in patients with heart failure: Insights from the AF-CHF echocardiographic sub-study.

In patients with heart failure and atrial fibrillation, the AF-CHF (Atrial Fibrillation and Congestive Heart Failure) trial did not demonstrate the superiority of rhythm control (RhyC) over a rate con...

Crystallization kinetics of Ga metallic nano-droplets under As flux.

We present an experimental investigation of the crystallization dynamics of Ga nano-droplets under As flux. The transformation of the metallic Ga contained in the droplets into a GaAs nano-island proc...

A Three-day PGF2α Plus eCG-based Fixed-time AI Protocol Improves Fertility Compared with Spontaneous Estrus in Dairy Cows with Silent Ovulation.

This study was designed to test the treatment with prostaglandin F2α (PGF2α) plus equine chorionic gonadotrophin (eCG) and GnRH 48 h later (PEG protocol) followed by fixed-time AI (FTAI) in dairy...

In-Season Root-Zone N Management for Mitigating Greenhouse Gas Emission and Reactive N Losses in Intensive Wheat Production.

Although both the grain yields and environmental costs of nitrogen (N) fertilization are gaining more public and scientific debate, the complex linkages among crop productivity, N application rate, en...

Effect of hydrion evolution by polylactic-co-glycolic acid coating on degradation rate of pure iron.

For biodegradable iron coronary stents, the major problem is the low degradation rate in body environment. In this study, a new strategy was proposed to increase the degradation rate of iron in vitro....

Lack of Impact on Polyp Detection by Fellow Involvement During Colonoscopy: A Meta-Analysis.

BACKGROUND: Conflicting data regarding the impact of fellow involvement during colonoscopy on the adenoma detection rate (ADR) and polyp detection rate (PDR) have been reported in the literature. AIMS...

Five-year retrospective clinical study of indirect composite restorations luted with a light-cured composite in posterior teeth.

OBJECTIVES: The purpose of this study was to evaluate the clinical performance of indirect composite onlays-overlays bonded with a light-cured composite on vital molars. MATERIALS AND METHODS: Forty-o...

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells.

BACKGROUND: Aneuploidy is a feature of most cancer cells that is often accompanied by an elevated rate of chromosome mis-segregation termed chromosome instability (CIN). While CIN can act as a driver...

Theoretical Investigations on the Kinetics of H-Abstraction Reactions from CF3CH(OH)CF3 by OH Radicals.

The kinetic studies of the H-abstraction reaction of CF3CH(OH)CF3 with the OH radical, which is predicted to have two classes of possible reaction channels, were carried out. The minimum energy path a...

News Articles [ 2923 Associated News Articles listed on BioPortfolio]

Dennis R. Hill MD HDR Prostate Brachytherapy Specialist Compares Prostate Cancer Treatment Options: Not All Low Dose Rate Brachytherapy Isotopes Are the Same

Dennis R. HIll M.D. Radiation Oncologist at the Alta Bates Summit Medical Center in Oakland, CA continues his series of discussions on comparing the latest in prostate cancer treatment options. Oaklan...

Fewer young adults are smoking, but more people are obese, shows US survey

The prevalence of smoking among US adults is holding steady, at about 20%, while the obesity rate has risen despite the fact that more people say they are physically active, a new report has...

Calif. Unveils Tentative Price Tags For Health Plans On The Exchange

The monthly cost for policies sold on the state-run exchange came in lower than the 30 percent rate increases some had anticipated, though some consumers will still experience sharply higher premiums....

California Unveils Tentative Price Tags Of Insurance Plans On Health Exchange

The monthly cost for policies sold on the state-run exchange came in lower than the 30 percent rate increases some had anticipated, though some consumers will still experience sharply higher premiums....

CDC: Teen Births at Record Lows

(MedPage Today) -- The teen birth rate in the U.S. has fallen to a record low level, and recent declines have been steepest among Hispanic teenagers, the Centers for Disease Control said Thursday.

Concern over NHS bed occupancy rate

NHS bed occupancy rates soared above safe levels for the first three months of this year, official figures show.

Study: No higher cancer rate at Conn. Pratt plant

(AP)—Researchers examining the incidence of brain cancer at jet engine manufacturer Pratt & Whitney in Connecticut say they have found no statistically significant elevations in the rate of cancer a...

AAPS PharmSciTech: Agglomerated Oral Dosage Forms of Artemisinin/β-Cyclodextrin Spray-Dried Primary Microparticles Showing Increased Dissolution Rate and Bioavailability

Type: Original PaperArtemisinin, a poorly water-soluble antimalarial drug, presents a low and erratic bioavailability upon oral administration. The aim of this work was to study an agglomerated powder...

EWG Supports Nano-Engineered Mineral Sunscreens In 2013 Report

Sunscreens containing zinc oxide and titanium dioxide nanoparticles rate relatively highly in the Environmental Working Group’s annual Sunscreen Guide, though the advocacy group says greater transpa...

Study: No higher cancer rate at Conn. Pratt plants

EAST HARTFORD, Conn. (AP) — An 11-year study of the incidence of brain cancer at jet engine manufacturer Pratt & Whitney in the state ended Thursday with university researchers saying they found no...

Events [ 3 Associated Events listed on BioPortfolio]

CLINICAL TRIALS ASIA SUMMIT

Clinical Trials Asia Summit is a platform for key stake holders to engage and critically analyze the road map for further growth towards establishing sustainable leadership of India in global Clinical...

How to Write Sops - An Essential Course for Ensuring Compliance with Regulatory Requirements

How to Write Sops - An Essential Course for Ensuring Compliance with Regulatory Requirements

Improving Processes and Capa (Corrective and Preventative Action)

Improving Processes and Capa (Corrective and Preventative Action)

Companies [ 61 Associated Companies listed on BioPortfolio]

The Multiple Myeloma Research Foundation

Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 34 percent, one of the lowest of all cancers. In 2009, ap...

The Coca-Cola Company

The Coca-Cola Company (NYSE: KO) is the world’s largest beverage company, refreshing consumers with more than 500 sparkling and still brands. Together with Coca-Cola, recogni...

RemitDATA Inc. and SYNNEX Corporation

Founded in 2000, RemitDATA Inc. helps more than 75,000 healthcare providers improve revenue and cash collections by identifying and correcting performance issues in the post-adjud...

Planisware, Inc.

Planisware is the leading global provider of world-class project & portfolio management solutions. Planisware’s acclaimed configurability accommodates the company’s glob...

Achaogen, Inc.

Achaogen is a clinical-stage biopharmaceutical company focused on the discovery and development of antibiotics for the treatment of serious infections caused by multi-drug resista...

Guardian Pharmacy, LLC

Guardian Pharmacy, LLC, headquartered in Atlanta, Ga., is one of the nation’s largest institutional pharmacy companies and ranks among Georgia’s fastest growing privatel...

Multiple Myeloma Research Foundation (MMRF)

Multiple myeloma is an incurable blood cancer. The five-year relative survival rate for multiple myeloma is approximately 38 percent, one of the lowest of all cancers. In 2010, mo...

The Aetna Foundation, Inc.

The Aetna Foundation, Inc. is the independent charitable and philanthropic arm of Aetna Inc. Since 1980, Aetna and the Aetna Foundation have contributed $394 million in grants and...

Valencell, Inc.

Founded in 2006 and headquartered in Raleigh, North Carolina, Valencell develops physiological monitoring technology and licenses this technology to industry partners for integrat...

The Coca-Cola Company and Atlanta Ronald McDonald House Charities

The Coca-Cola Company (NYSE: KO) is the world's largest beverage company, refreshing consumers with more than 500 sparkling and still brands. Led by Coca-Cola, the world's most va...

Clinical Trials [ 812 Associated Clinical Trials listed on BioPortfolio]

Gene Expression in Cumulus Cells to Predict Pregnancy

The purpose of this study is to determine the performance of a genetic assay, GemART, in cumulus cells predictive of embryo viability, and pregnancy success in women undergoing in vitro fe...

An Interventional Study to Assess the Efficacy and Safety of Buprenorphine in Korean Patients With Spinal Disorders

The purpose of this study is to assess the pain reduction rate after 8 weeks treatment of NORSPAN® from baseline. And secondary purpose are: pain reduction rate after 4 weeks treatment f...

Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma of the Head & Neck

Recent progress in treatment of recurrent/metastatic SCCHN has been made with the introduction of the taxanes. Docetaxel as a single agent has a response rate of 22-42% and 17% in patients...

Phase III Randomized Trial of Thalidomide/Dexamethasone vs VAD.

This study compares the response rate, overall response rate and survival of patients with multiple myeloma when randomized to two regimens (thalidomide+Dexamethasone vs. Vincristine+Adria...

Trial of the Impact of Vitamin A on Maternal Mortality

Main objectives: To evaluate the impact of weekly vitamin A supplementation (VAS) to women of reproductive age (15-45 years) on maternal mortality in rural Ghana, and to compare this with...

Iodixanol in Multidetector-Row Computed Tomography-Coronary Angiography (MDCT-CA)

Image quality in coronary artery computed tomography is influenced by the heart rate variation during the examination. The purpose of this clinical trial is to investigate the change in he...

Perioperative Effect of Atenolol on Cytokine Profiles

Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery...

Study Comparing Short Infusion Vs. Fixed Dose of Cisplatin + Gemcitabine in Non Small Cell Lung Cancer.

The purposes of this study are to determine: How standard gemcitabine plus cisplatin compares to fixed dose rate of gemcitabine plus cisplatin in the treatment of non-small cell lung canc...

Strategies for Suspected Pulmonary Embolism in Emergency Departments

Aims: 1) To evaluate the effectiveness of two interventions aimed at improving the management of patients with suspected pulmonary embolism: Written guidelines and Computer-Assisted Decisi...

Response of Cardiac Resynchronization Therapy Optimization With Ventricle to Ventricle Timing in Heart Failure Patients

The purpose of the study is to evaluate the benefit of interventricular (V-V) delay optimization in reducing the non-responder rate in patients with cardiac resynchronization defibrillator...

Medical and Biotech [MESH] Definitions

Transcriptional Elongation Factors

Transcription factors whose primary function is to regulate the rate in which RNA is transcribed.

Iron Regulatory Protein 2

A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.

Glycemic Index

A numerical system of measuring the rate of BLOOD GLUCOSE generation by a particular food item as compared to a reference item, such as glucose = 100. Foods with higher glycemic index numbers create greater blood sugar swings. These numbers do not correspond to calories or amounts of food intake but rather, depend on the rates of digestion and absorption of these food items.

Poly(a)-binding Protein Ii

A poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. The protein requires a minimum of ten ADENOSINE nucleotides in order for binding to mRNA. Once bound it works in conjunction with CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR to stimulate the rate of poly A synthesis by POLY A POLYMERASE. Once poly-A tails reach around 250 nucleotides in length poly(A) binding protein II no longer stimulates POLYADENYLATION. Mutations within a GCG repeat region in the gene for poly(A) binding protein II have been shown to cause the disease MUSCULAR DYSTROPHY, OCULOPHARYNGEAL.

Eukaryotic Initiation Factors

Peptide initiation factors from eukaryotic organisms. Over twelve factors are involved in PEPTIDE CHAIN INITIATION, TRANSLATIONAL in eukaryotic cells. Many of these factors play a role in controlling the rate of MRNA TRANSLATION.

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