Rectum - Biotech, Pharma and Life Science Channel
PubMed Articles
PURPOSE: The sigmoidorectal junction (SRJ) has been defined as an anatomical sphincter with particular physiological behavior that regulates sigmoid and rectum evacuation. Its function in clinical con...
AIM: Locally advanced fixed T4 rectal cancer has a poor prognosis and no standard treatment strategy. The aim of this study was to investigate safety and efficacy of neoadjuvant chemoradiotherapy usin...
PURPOSE: To determine the diagnostic performance of MRI in assessing local tumour extent and evaluate associations between MRI features and survival in patients undergoing MRI before pelvic exenterati...
PURPOSE: It has been suggested that the cancer risk of migrants from low-income to high-income countries will converge toward the levels of their host country. However, comparisons with country of ori...
Rectal Microbicide Development.
The last few years have seen important progress in demonstrating the efficacy of oral pre-exposure prophylaxis, vaginal microbicides, and treatment as prevention as effective strategies for reducing t...
The majority of current models utilized for predicting toxicity in prostate cancer radiotherapy are based on dose-volume histograms. One of their main drawbacks is the lack of spatial accuracy, since...
Experience with wound complications after surgery for sacral tumors.
PURPOSE: The aim of this article is to summarize our experience in treating sacral wound complications after sacrectomy. We focus, in particular, on factors associated with wound complications, includ...
Objective-To compare the outcome of horses with nephrosplenic entrapment of the large colon (NSELC) that were treated nonsurgically by IV administration of phenylephrine and exercise with that of hors...
Endometriosis involving the mucosa of the intestinal tract: a clinicopathologic study of 15 cases.
Endometriosis involving the mucosa of the intestines is rare, but may lead to diagnostic pitfalls. We reviewed 15 cases (seven biopsies and eight resections) from 14 patients. The patients' mean age i...
Risk of colorectal cancer associated with active smoking among female teachers.
PURPOSE: The objective of this study was to examine the risk of colorectal cancer associated with active smoking among members of the California Teachers Study (CTS), a large cohort of female public s...
News Articles
Friday Weird Science: What's your fart volume?
Have you ever wondered just HOW much you fart per day ? Like...would it fill a soda can? A soda bottle? And would you be willing to stick a tight fitting tube up your rectum and wear it around all da...
Studies Show Improved IBD Diagnoses and Treatments
NEW YORK, NY--(Marketwired - May 17, 2013) - Four important findings from the Pediatric Resource Organization for Kids with Inflammatory Intestinal Digestive Diseases (PRO-KIIDS) will be presented th...
Dennis R. Hill MD HDR Prostate Brachytherapy Specialist Compares Prostate Cancer Treatment Options
Dennis R. HIll M.D. Radiation Oncologist at the Alta Bates Summit Medical Center in Oakland, CA continues his series of discussions on comparing the latest in prostate cancer treatment options. Oaklan...
Anal Cancer Rates Appear to Be On the Rise in the U.S.
The number of people in the United States with anal cancer has tripled since the 1970s, according to the results of a study published in the Journal of Clinical Oncology. Anal cancer is an uncommon ty...
Dr. Deborah Schrag is recognized among Castle Connolly's Top Doctors® for Boston, MA region in 2013
BOSTON, May 3, 2013 /PRNewswire-USNewswire/ -- Castle Connolly Medical Ltd., America's trusted source for identifying Top Doctors, has selected Boston's Medical Oncology specialist Dr. Deborah Sc...
Psoriatic arthritis linked to increased risk of Crohn's disease in women
Women with psoriasis and psoriatic arthritis appear to face an increased risk of Crohn's disease, a study has found.Psoriatic arthritis is a painful inflammatory joint disease that is often associ...
Patients Honor Dr. William Harb for Compassion
Dr. William Harb of Nashville, TN is ranked among the top physicians in the nation based on patient reviews. NASHVILLE, Tenn., April 15, 2013 /PRNewswire-USNewswire/ -- Patients' Choice has anno...
Type: Original PaperPurposeTo investigate the potential of thermosensitive and biadhesive nanomicelles in improving the bioavailability of docetaxel (DCT) and its chemotherapeutic effect.MethodDCT-loa...
Bowel cancer up 30% for men in 35 years
A rise in bowel cancer among men has been reported across the UK media. The news is based on figures released by Cancer Research UK, coinciding with the start of bowel cancer awareness month and the l...
Saint Luke's Suggests Colonoscopy for Colorectal Cancer Prevention
Cancer screening procedure most important for colorectal cancer prevention for people over 50 or those with high risk factors; Colonoscopy recommended once every 10 years KANSAS CITY, Mo., M...
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Clinical Trials
Phase 2A Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer
The purpose of the phase 2A component of this study is to determine if giving the immune molecule NPC-1C to individuals who have cancer of the pancreas or gastrointestinal tract (colon or...
Sacral Nerve Stimulation Therapy for the Treatment of Chronic Fecal Incontinence
Fecal incontinence (FI) is a difficulty in storing gas, liquid stool or solid stool (bowel movement) in order to expel it at a proper time and place. Patients who suffer from FI may exper...
Lactic Acid in the Rectum and Life-Threatening Infection
Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of lactic acid. The investigators hypothesize, that the...
Botox as a Treatment for Chronic Male Pelvic Pain Syndrome
Chronic pelvic pain syndrome (CPPS) is thought to affect approximately 8% of men aged 18 and older. Patients with this condition experience pain in the perineum, the genitalia, and the rec...
Celebrex With Preoperative Chemoradiation - Rectal Cancer
Colorectal carcinoma is the third most common cause of death from cancer. Approximately, 30% of colorectal carcinomas involve the rectum. Optimizing local control in the pelvis while reduc...
Julius Schachter, PhD, from the Department of Laboratory Medicine at UCSF, and Jeffrey Klausner, MD, from the Department of Public Health, are conducting a study to evaluate a type of test...
The purpose of this study is to evaluate the treatment of a cancerous disease of the peritoneum with complete cytoreductive surgery with intraperitoneal chemohyperthermia using oxaliplatin...
Prophylactic Antibiotic Treatment During Vaginal Repair
Prolapse of the uterus, bladder and rectum is a common condition in multiparous and/or elderly women. The number of operations for vaginal repair is increasing in Denmark, but there is no...
Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries
The principle objective of this research is to more precisely determine the degree of benefit that hyperbaric oxygen therapy affords in the treatment of late radiation tissue injury....
Neoadjuvant Colorectal Cancer With Unresectable Liver Metastases
The study was terminated early due to low enrollment with only 2 subjects enrolled and treated after being open for enrollment for over a year. Therefore, no meaningful efficacy analyses...
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Medical and Biotech [MESH] Definitions
Ultrasound, High-intensity Focused, Transrectal
Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).
Colonic Pouches
Sacs or reservoirs created to function in place of the COLON and/or RECTUM in patients who have undergone restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).
Digital Rectal Examination
A physical examination in which the qualified health care worker inserts a lubricated, gloved finger of one hand into the RECTUM and may use the other hand to press on the lower ABDOMEN or pelvic area to palpate for abnormalities in the lower rectum, and nearby organs or tissues. The method is commonly used to check the lower rectum, the PROSTATE gland in men, and the UTERUS and OVARIES in women.
Leukokeratosis, Hereditary Mucosal
An autosomal dominant disorder that is manifested by thickened spongiform ORAL MUCOSA with a white opalescent tint. Other MUCOSAL TISSUE may also be involved mucosa found in the VAGINA; RECTUM, and NASAL CAVITY may be similarly involved. This form of LEUKOKERATOSIS can be caused by a mutation in the gene for KERATIN 4 and is not considered a PRENEOPLASTIC CONDITION.
Adenomatous Polyposis Coli
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.
