Regulation of Calcium Metabolism - Biotech, Pharma and Life Science Channel
PubMed Articles
KCNN4 Channels participate in the EMT induced by PRL-3 in colorectal cancer.
Studies have shown that phosphatase of regenerating liver-3 (PRL-3) promotes the invasion, migration, and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition (EMT). Ho...
Disturbances in Ca(2+) homeostasis have been implicated in a variety of neuro-pathological conditions including Parkinson's disease (PD). In the present study, we investigated the potential protective...
New fluorescent oligo(phenylene ethynylene)-DNA hydrogels have been prepared and used for the controllable biocidal activity driven by DNase. This study opens a new way of controllable drug release an...
Effects of High Zinc Levels on the Lipid Synthesis in Rat Hepatocytes.
Zinc deficiency impairs the hepatic lipid metabolism. Previous studies were focused on the negative effects of zinc deficiency on the hepatic lipid metabolism. A few studies investigated the effects o...
Regulation of proinflammatory and anti-inflammatory Th17 cells.
The neuropsychiatry of inborn errors of metabolism.
A number of metabolic disorders that affect the central nervous system can present in childhood, adolescence or adulthood as a phenocopy of a major psychiatric syndrome such as psychosis, depression,...
Interleukins are proteins involved in the immune system and have been related to the endocrine regulation of the hypothalamic-pituitary-adrenal axis as well as to the secretion of ACTH, prolactin (PRL...
Kidney stone disease is associated with renal fibrosis by the unclear mechanisms. We hypothesized that calcium oxalate (CaOx), a major crystalline component of kidney stones, could induce secretion of...
Neurogenic differentiation factor (NeuroD) is a transcription factor involved in the differentiation of neurons and in the control of energy balance and metabolism. It plays a key role in type 1 and t...
Mechanisms of Acute Coronary Syndromes and Their Implications for Therapy.
The notion that heart attacks develop from coronary-artery stenosis is an oversimplification of a process involving lipid metabolism, inflammation, macrophage activation, collagen breakdown, and plaqu...
News Articles
Study Shows Eating Junk Food While Pregnant May Increase Likelihood of Childhood Obesity
Recent studies have shown that eating junk food during pregnancy can have lasting effects on your child. Liquid Health suggests a healthy diet and a high quality-prenatal vitamin to get all the essen...
Delphinol Clinically Proven in the Mainenance of Glucose Balance
Bradenton, FL, May 24, 2013 --(PR.com)-- Overeating and lack of physical exercise is turning into a global pandemia with metabolic syndrome as a hallmark and type II diabetes representing the fastest...
Register to Access Webinar Playback - The Impact of Financial Regulation on M&A in 2013
London, UK (PRWEB) May 24, 2013 Wednesday, 15th May 2013 | 10am BST | 5pm HKT Duration: 60mins Register to access webinar playback: http://bit.ly/10Rt0ZH Ongoing regulatory changes are...
Mass Spectrometers Offer Insight Into The Dazzling Impact Of Insulin In Cells
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes. The b...
Health2Go Announces Research That DHEA Helps Depression
DHEA, dehydroepiandrosterone, a natural base building block for hormones has been shown in many top research studies that higher levels of normally occurring DHEA staves off depression. It turns out...
SANTA MONICA, Calif., May 23, 2013 /PRNewswire-USNewswire/ -- Consumer Watchdog responded today to the news that the state's three largest health insurance companies would continue to dominate the hea...
EU to kick off talks on stronger trade mark system
Next week the European Parliament’s legal affairs committee (JURI) will examine a draft Regulation aimed at streamlining the procedures for obtaining a single trade mark valid throughout the EU...
Cardiovascular Systems Presents New Late-Breaking Coronary Results at EuroPCR Conference
ORBIT II trial met primary endpoints treating patient population in which 99.3% of subjects had severely calcified lesions 30-day freedom from...
OPKO Surpasses 50% Enrollment in First Phase 3 Trial of RayaldyTM (CTAP101 Capsules)
OPKO Health, Inc. (NYSE: OPK), has surpassed 50% enrollment in the first phase 3 trial of RayaldyTM to treat patients with secondary hyperparathyroidism (SHPT), stage 3 or 4 chron...
Can Calcium Supplements Lower Heart Attack Risk in Women?
A new study finds that women taking 1,000 milligrams of calcium a day have a 22 percent lower risk of dying, contradicting previous studied linking calcium to an increased risk of heart attacks. There...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
The Cosmetics Regulation (EC) No 1223/2009 of the European Parliament and of the Council of November 2009
Smithers Viscient has brought together an exciting new event for June 2013, Environmental Science Forum.
Companies
American Association of Clinical Endocrinologists
AACE is a professional medical organization with more than 6,000 members in the United States and 91 other countries. AACE members are physicians who specialize in endocrinology, diabetes, and metabol...
From its establishment in 1977, simply as a Distributor of diagnostic products, IDS has become a globally-recognised innovator and marketeer in the IVD industry.The Company is particularly well-known...
Source BioScience LifeSciences
Source BioScience LifeSciences are European leaders in DNA sequencing, genomic services, bioinformatic analyses and offers a comprehensive portfolio of genomic reagents and antibodies. Source Bio...
Plandaí Biotechnology, Inc. intends to transform the world of nutraceuticals by making available extracts from live plant material that deliver the highest levels of bioavailability curr...
Interleukin Genetics, Inc. (OTCQB: ILIU) develops and markets a line of genetic tests under the Inherent Health® brand. The products empower individuals to prevent ce...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the worldâs largest...
Pacific Biosciences of California, Inc.
Pacific Biosciencesâ mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercializati...
AllCells (www.AllCells.com) is a global biotechnology company founded in 1998 to provide researchers with a reliable supply of biologically relevant, consistent quality pri...
Digicom Electronics offers advanced electronics manufacturing with Made in the USA Quality that fits the needs of larger enterprises while at the same time providing the benefits...
Clinical Trials
Positron Emission Tomography (PET) to Study Brain Signaling
This study uses positron emission tomography (PET) to examine brain function and signaling involving phospholipids, and to see how signaling is related to blood flow. Much of the brain is...
Phase I study to evaluate the excretion of radioactivity, the metabolic profile, pharmacokinetics, safety and tolerability following a single oral administration of [14C] Prucalopride Succ...
Ventricular Arrhythmias in Uremic Cardiomyopathy
There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds...
Treatment of Osteopenia With Melatonin
The aim of the study is to assess the effect of melatonin treatment in patients with osteopenia on BMD, muscle function, quality of life and calcium homeostasis.
Glutamine Enriched Total Parenteral Feeding and Proline Metabolism in Severely Burned Patients
Proline is a non-essential amino acid that helps with collagen formation. Collagen is one of the main ingredients of skin, bone, tendons, and connective tissue. It is thought that proline...
Zoledronic Acid in the Management of Patients With Asymptomatic/Early Stage Multiple Myeloma
Evidence for the beneficial effects of bisphosphonates on bone resorption in multiple myeloma has been reported extensively, showing reductions in skeletal events and improvement of severa...
Family Preparation Study For Withdrawal of Mechanical Ventilation From Their Family Member
Using the self-regulation theory, an intervention to prepare families for that experience was developed. This study will assess the impact of the intervention on a family’s evaluation of...
Glutamine and Intestinal Protein Metabolism
Gut barrier plays a major role in defence of the organism. During catabolic states, like major surgery or inflammation, gut barrier could be altered. It has been reported that preoperative...
Janssen - Glucose Regulation/Risp/Olanz
Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions. A...
Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole
This proposal aims to use well-validated methodologies such as dual energy x-ray absorptiometry (DEXA), frequently sampled oral glucose tolerance tests (fsOGTTs), and hyperinsulinemic eugl...
Videos
Medical and Biotech [MESH] Definitions
Government Regulation
Exercise of governmental authority to control conduct.
Heterogeneous-nuclear Ribonucleoprotein K
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Integration Host Factors
Bacterial proteins that are used by BACTERIOPHAGES to incorporate their DNA into the DNA of the "host" bacteria. They are DNA-binding proteins that function in genetic recombination as well as in transcriptional and translational regulation.
Tata Box Binding Protein-like Proteins
A class of proteins related in structure and function to TATA-BOX BINDING PROTEIN that can take the place of TATA-BOX BINDING PROTEIN in the transcription initiation complex. They are found in most multicellular organisms and may be involved in tissue-specific promoter regulation. They bind to DNA and interact with TATA-BINDING PROTEIN ASSOCIATED FACTORS, however they may lack specificity for the TATA-BOX.
Iron Regulatory Protein 1
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.
