Renal Glucosuria - Biotech, Pharma and Life Science Channel
PubMed Articles
Recently, novel molecular targeted agents markedly changed the treatment of renal cell carcinoma (RCC), with promising results. However, there is little understanding of how these agents affect immune...
Temsirolimus controlled metastatic advanced renal cell carcinoma for over 4 years: a case study.
We present a case report of long-term response with temsirolimus in cytokine refractory metastatic renal cell carcinoma (RCC). A 74-year-old Japanese man was diagnosed with advanced RCC in November 20...
We retrospectively analyzed metastatic renal cell carcinoma (RCC) patients treated with 3 targeted agents. Patients started the sequence with a tyrosine kinase inhibitor (TKI), sunitinib or sorafenib,...
Rivaroxaban (Xarelto(®)), a direct factor Xa inhibitor, is approved for the prevention of stroke and systemic embolism in patients with atrial fibrillation (AF) in Canada or those with nonvalvular AF...
Clinical Pharmacology of Axitinib.
Axitinib is a potent and selective second-generation inhibitor of vascular endothelial growth factor receptors 1, 2, and 3 that is approved in the US and several other countries for treatment of patie...
The Sympathetic Nervous System in Obesity Hypertension.
Abundant evidence supports a role of the sympathetic nervous system in the pathogenesis of obesity-related hypertension. However, the nature and temporal progression of mechanisms underlying this symp...
Bee pollen and propolis are popular, traditional health foods. The objective of the current study was to investigate the anti-mutagenic, anti-histopathologic and antioxidant effects among water extrac...
BACKGROUND: The purpose of the present study was to determine the prevalence of diabetes and its effect on surgical outcomes in patients undergoing emergent, in-patient cholecystectomy for acute chole...
Secondary polycythemia with increased production of erythropoietin (EPO) is known to occur in kidney diseases such as hydronephrosis and cystic disease, but the mechanism remains unclear. We report an...
News Articles
[Rockwell Medical] nets $38mm through FOPO
[Rockwell Medical Inc.] (end-stage renal and chronic kidney disease treatments) has netted $38mm through the follow-on public offering of 13.2mm common shares (including the overallotment) at $3.05. T...
Revitalising renal care: Diaverum at ERA/EDTA 2013 in Istanbul
Renal care provider presents service portfolio at European event and results of ORAL-D study Diaverum, one of the world’s leading renal care service providers, is pre...
Diaverum to present results of latest research work at ERA/EDTA 2013
Diaverum, one of the world's leading renal care service providers, is presenting its service portfolio and the results of its latest research at the ERA/EDTA 2013.
Compounded Prescription Therapies By Pentec Health Inc.: Recall - Lack Of Sterility Assurance
Audience: Pharmacy, Patient, Health Professional [Posted 05/17/2013] ISSUE: Pentec Health, Inc. initiated a limited, voluntary recall of in-date nutritional prescriptions for renal patients du...
LDL Won't Help Spot MI in Renal Patients (CME/CE)
(MedPage Today) -- High LDL cholesterol levels were a weak predictor of myocardial infarction risk in patients with chronic kidney disease, a study found.
Mom’s Meals Insights: Ask Not What an ‘Older American’ Can Do for You
There are now more Americans age 65 and older than at any other time in U.S. Mom's Meals offers tips on how to serve those who have served so well. Des Moines, IA (PRWEB) May 16, 2013 There are n...
BOOTHWYN, Pa., May 16, 2013 /PRNewswire-USNewswire/ -- Pentec Health, Inc. has decided to initiate a limited, voluntary recall of in-date nutritional prescriptions for renal patients due to lack of st...
Lund, Sweden, May 16, 2013, Active Biotech (NASDAQ OMX NORDIC: ACTI) will present data from two of its oncology projects, the drug candidates tasquinimod for the treatment of prostate cancer and ANYA...
Rockwell Medical Announces the Exercise of Over-Allotment Option
WIXOM, MI -- (Marketwired) -- 05/16/13 -- Rockwell Medical, Inc. (NASDAQ: RMTI), a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD)...
Widespread But Neglected Disease Leptospirosis A Significant Health Threat In Africa
The newest public health threat in Africa, scientists have found, is coming from a previously unknown source: the banded mongoose. Leptospirosis, the disease is called. And the banded mongoose carries...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
Companies
Relypsa, Inc. is a, clinical-stage biopharmaceutical company leading the discovery and development of novel non-absorbed polymeric drugs for important applications in cardiovascul...
Kite Pharma, Inc. is a privately held development stage biotechnology company engaged in the design and development of cutting-edge immunotherapeutic products to treat different c...
American Renal Associates LLC (âARAâ) is the operating subsidiary of American Renal Holdings, Inc. and is a leading owner and provider of outpatient kidney dialysis cent...
Vivere Health is a leading network of Fertility Centers of Excellence. The company, recently founded in 2010, serves as the business backbone for leading reproductive endocrino...
Established in 1982, Spectra Laboratories, Inc. is the leading provider of renal-specific laboratory testing services in the United States. The companyâs state-of-the-art ana...
DaVita Inc., a Fortune 500® company, is a leading provider of kidney care in the United States, delivering dialysis services to patients with chronic kidney failure and end sta...
Renal Ventures Management, LLC
Renal Ventures Management, LLC is a leading provider of dialysis services. The company partners with top physicians to provide patients with knowledgeable, compassionate and quali...
Cibiem is a medical device company leveraging its proprietary, minimally invasive, catheter-based approach focused on Carotid Body Modulation⢠(CBM) for the treatment of symp...
Thrasos TherapeuticsTM is a private, clinical stage, biotherapeutics company focused on the discovery and development of targeted therapies for the prevention and treatment of kid...
DaVita HealthCare Partners, a Fortune 500® company, is the parent company of DaVita and HealthCare Partners. DaVita is a leading provider of kidney care in the United States, d...
Clinical Trials
Suspension of Mechanical Ventilation in Ureteroscopic Lithotripsy Under General Anesthesia
For some upper ureteral and renal stones,ureteroscopic lithotripsy needs to be performed under general anesthesia with interrupted suspension of mechanical ventilation, which could result...
An observational cohort study on safety and efficacy to generate additional data on the benefit/risk profile of the 150 mg dose of Pradaxa in patients with renal impairment
Tc-99m Renography and Cisplatin-Induced Nephrotoxicity
Cisplatin is a heavy-metal complex widely used in the treatment of a variety of malignancies, including small cell and non-small cell lung cancer, ovarian, bladder, head and neck, esophage...
Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Computed Tomography
It is well known that X-ray contrast media can affect kidney function in some patients, especially when administered intra-arterially, and patients who already suffer from reduced kidney f...
Effects of Anemia Correction on Vascular and Monocyte Function in Renal Transplant Recipients
Correction of anaemia in renal transplant recipients by parenteral application of recombinant erythropoietin and if necessary iron will improve large artery function (endothelial function...
Chronic transplant nephropathy and cardiovascular death are the main reasons for loss of transplanted organs after kidney transplantation. Vascular changes, induced by hypertension and/or...
The trial is planned as a multicentric, randomized, prospective, open study in accordance with a 1/1 plan, on parallel groups and 2 arms of treatment. A total of 200 patients with chronic...
Use of a Ureteral Access Sheath During Ureteroscopy and Its Effect on Stone Free Rate
Patients with upper ureteral or renal stones will be randomized to undergoing ureteroscopy with or without a ureteral access sheath. The sheath is designed to facilitate ureteroscope inser...
Pilot Study of Mycophenolate Mofetil in Congenital Uropathies
Congenital or hereditary structural anomalies of the genitourinary tract account for approximately half of all cases of end stage renal disease in the pediatric population. Despite optimal...
Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans
African Americans receiving a kidney transplant are considered at high risk for early rejection of their transplanted kidney and require more immunosuppression to maintain their kidney tra...
Videos
3 Reactivos Glucosuria
La glucosa es filtrada por el glomérulo en el riñón; es reabsorbida a nivel del túbulo contorneado proximal. Si la concentración de glucosa en sangre aumenta...
Medical and Biotech [MESH] Definitions
Hyperuricemia
Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.
Parathyroid Hormone-related Protein
A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.
Hyperparathyroidism, Primary
A condition of abnormally elevated output of PARATHYROID HORMONE due to parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. It is characterized by the combination of HYPERCALCEMIA, phosphaturia, elevated renal 1,25-DIHYDROXYVITAMIN D3 synthesis, and increased BONE RESORPTION.
Sodium-phosphate Cotransporter Proteins, Type Ii
A family of sodium-phosphate cotransporter proteins with eight transmembrane domains. They are present primarily in the KIDNEY and SMALL INTESTINE and are responsible for renal and small intestinal epithelial transport of phosphate.
Sodium-phosphate Cotransporter Proteins, Type Iia
An electrogenic sodium-dependent phosphate transporter. It is present primarily in BRUSH BORDER membranes of PROXIMAL RENAL TUBULES.