Resection of metastases - Biotech, Pharma and Life Science Channel
PubMed Articles
PR (PRDI-BF1 and RIZ) domain containing proteins (PRDM) have been indicated to play important roles in several human cancers. The objectives of this study were to determine the frequency and prognosti...
The aim of this study was to interrogate whether blood-borne inflammatory and nutritional markers predict long-term survival and response to neoadjuvant chemotherapy in radically treated oesophagogast...
Malignant meningitis presenting as pseudotumor cerebri.
Malignant leptomeningitis can present as the clinical syndrome of pseudotumor cerebri due to infiltration of arachnoid villi in the superior sagittal sinus. We show that malignant pachymeningitis can...
Metastatic tumor antigen 1 (MTA1) overexpression is closely associated with postoperative recurrence of hepatocellular carcinoma (HCC). It has been suggested that pegylated interferon (Peg-IFN) can pr...
Transoral endoscopic odontoidectomy to decompress the cervicomedullary junction.
STUDY DESIGN.: Clinical study. OBJECTIVE.: To investigate the feasibility of the transoral endoscopic odontoidectomy without occipitocervical fusion. SUMMARY OF BACKGROUND DATA.: Endoscopic transnasal...
The American Cancer Society estimated 1.5 million new cancer cases in the United States in 2012. Although the exact number is not known, it is estimated that brain metastases occur in 20-40% of cancer...
Cultivation-dependent plasticity of melanoma phenotype.
Malignant melanoma is a highly aggressive tumor with increasing incidence and high mortality. The importance of immunohistochemistry in diagnosis of the primary tumor and in early identification of me...
PURPOSE: The response of colorectal liver metastases to the cytotoxic agent irinotecan varies widely. Attempts to correlate tumour metabolism with response have been mixed. This study investigated the...
The ErbB receptor family has been implicated in brain metastases (BM) formation in various cancer types and specific targeted therapies are available. We investigated the overexpression of EGFR, HER2...
T1 bladder cancer : Role of documentation for bladder tumor findings and targeted second resection.
BACKGROUND: For control resection of T1 bladder tumors an exact relocalization of the previously infiltrating tumor spread can be complicated by postreactive alterations, multiple scar tissue or chang...
News Articles
Some Squamous Cell Skin Cancers Are Deadly
Cutaneous squamous cell carcinoma is usually easily treated with surgery; however, a subsection of patients with specific disease risk factors are more likely to develop metastases and die from the di...
Diabetes And Glucose Meters, Prostate Cancer Bone Metastases, Thyroid Autoimmunity And More
Researchers from the Icahn School of Medicine at Mount Sinai are presenting several new studies at ENDO 2013, The Endocrine Society's Annual Meeting & Expo (ENDO) from June 15-18 in San Francisco. Mou...
New drug proving effective in attacking advanced prostate cancer
INDIANAPOLIS, June 17, 2013 /PRNewswire-USNewswire/ -- Franciscan St. Francis Health Cancer Center today (June 17) is the first medical facility in Indiana to use a new drug to treat men with advanced...
Diabetics who use meters to monitor their glucose have better control over disease
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Mount Sinai researchers will demonstrate new data on diabetes self-management, as well as the role of prostastic acid phosphatase in Prostat...
FDA approves the use of denosumab for bone cancer
The U. S. Food and Drug Administration approved denosumab for the treatment of adults and skeletally mature adolescents with giant cell tumour of bone that is unresectable or where surgical resection...
FDA Approves Amgen's XGEVA® (denosumab) For The Treatment Of Giant Cell Tumor Of Bone
THOUSAND OAKS, Calif., June 13, 2013 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication for XGEVA® (denosumab) for...
Amgen’s Xgeva Gains FDA Nod For Use In Rare Bone Tumor
Approval of denosumab for giant cell tumor of the bone comes more than a year after Amgen’s failed bid to add a more commercially significant indication for prevention of bone metastases in patients...
Narrower Margin OK for Resection of Colorectal Liver Metastases
When resecting colorectal liver metastases, a 1-mm margin should be the standard of care, instead of a 1-cm margin, according to researchers at two major liver resection centers in the UK. Reuters H...
MR-Guided, Focused Ultrasound Targeted at Bone Metastases Helps Aleve Pain
A high-dose of ultrasound targeted to painful bone metastases appears to rapidly bring patients relief, and with largely bearable side...
Prostate Enzyme Enables Detection Of Metastases During Molecular Imaging
No matter where they have hidden, metastatic prostate cancer cells still express some of the same signaling as normal prostate cells; in some cases even more so, as with the PSMA enzyme. Harnessing th...
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OncoMed is a clinical development-stage biopharmaceutical company focused on discovering and developing first-in-class monoclonal antibody therapeutics targeting cancer stem cells, or CSCs. Our appr...
YES is a grassroots organization that provides cancer patients with support, resources, options, education and hope in their fight against liver tumors. It is made up of sur...
Clinical Trials
This study will test the investigational antibody, anti-OX40, in combination with stereotactic body radiation in breast cancer patients that have liver or lung metastases and have received...
Low Dose Vaccine Study for Surgically Resected Pancreatic Cancer
To assess the response for subjects with pancreatic cancer that have undergone surgical resection and treatment with a vaccine given with or without chemotherapy and chemoradiation.
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain. What we learn from this study may help us find new way...
Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancer
The purpose of this study is to evaluate a new blood test as a way to follow the effect of Zometa in treating bone metastases due to lung cancer.
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigator...
A Study Of Nasopharyngeal Carcinoma (NPC) Treated With Celecoxib And ZD1839
EGFR and COX-2 are involved in tumorigenesis, angiogenesis and metastases and are frequently over expressed in NPC.COX-2 and EGFR inhibitors are active in NPC.There is synergistic action b...
The overall goal of this study is to determine how FDG-PET can be incorporated into the assessment of the axilla in the staging and treatment of women with early stage breast cancer....
The purpose of this study is to determine whether the addition of bevacizumab, to hepatic arterial therapy with floxuridine (FUDR) and dexamethasone (Dex) (regional chemotherapy), and eith...
With a major liver or pancreas operation, there is a chance that one will require a transfusion of blood products (either red blood cells or plasma). This may be necessary during the oper...
Positron Emission Tomography (PET) Interest in the Follow Up of Colorectal Cancer Stage II and III
The follow up of colorectal cancer after curative surgery has to find loco-regional relapses or synchronous metastases, and to detect adenomas and new cancer on the rest of the colon. The...
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Medical and Biotech [MESH] Definitions
Neck Dissection
Dissection in the neck to remove all disease tissues including cervical LYMPH NODES and to leave an adequate margin of normal tissue. This type of surgery is usually used in tumors or cervical metastases in the head and neck. The prototype of neck dissection is the radical neck dissection described by Crile in 1906.
Multiple Pulmonary Nodules
A number of small lung lesions characterized by small round masses of 2- to 3-mm in diameter. They are usually detected by chest CT scans (COMPUTED TOMOGRAPHY, X-RAY). Such nodules can be associated with metastases of malignancies inside or outside the lung, benign granulomas, or other lesions.
Prostatectomy
Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).
Short Bowel Syndrome
A malabsorption syndrome resulting from extensive operative resection of the SMALL INTESTINE, the absorptive region of the GASTROINTESTINAL TRACT.
Thymoma
A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)
