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Respiratory syncytial virus RSV Vaccines - Biotech, Pharma and Life Science Channel

17:22 EDT 30th June 2016 | BioPortfolio

Respiratory syncytial virus (RSV) infection, which manifests primarily as bronchiolitis and/or viral pneumonia, is the leading cause of lower respiratory tract infection in infants and young children. In the US, RSV LRT infection develops annually in 4-5 million children, and more than 125,000 children are admitted per year for RSV-related illness. RSV disease is the no.1 cause of hospitalization in babies under a year of age in the US. While a monoclonal antibody is commercially available to help prevent RSV disease in infants and children at high risk for severe lung disease from RSV, a RSV vaccine still is not on the market. A number of RSV vaccine candidates have entered clinical development and further are to follow. Also, next generation antibodies against RSV with improved features are in the development pipeline as well as new therapies based on silencing RSV RNA or inhibiting key targets of the virus.

News Articles [928 Associated News Articles listed on BioPortfolio]

First-In-Human Study Of Immbio’s Novel Pneumococcal Vaccine Pnubiovax Shows Vaccine To Be Safe And Immunogenic

Data presented as invited oral presentation at 10th International Symposium on Pneumococci & Pneumococcal Diseases • Antibody responses to ubiquitous antigens across strains shown, indica...

Flublok® Influenza Vaccine is a great alternative for FluMist for adults 18 and older

MERIDEN, Conn., June 30, 2016 /PRNewswire/ -- On Wednesday, the CDC's Advisory Committee on Immunization Practices (ACIP) recommended against the use of live attenuated influenza vaccine (LAIV), ...

GeoVax Announces Filing of Investigational New Drug Application for HIV Human Clinical Trial

ATLANTA, GA -- (Marketwired) -- 06/30/16 -- GeoVax Labs, Inc. (OTCQB: GOVX), a biotechnology company developing human vaccines, announced today the filing of an Investigational New Drug (IND) applica...

Universal Cancer Vaccine Trial Highlights Hope for New Cancer Treatments

By August Patterson, Senior Staff Writer, Financial Press Media Group, Inc. BATON ROUGE, LA, June 29, 2016 /PRNewswire/ - Researchers at Johannes Gutenberg University of Mainz in Germany have ...

Pennsylvania Launches New Zika Virus Prevention and Awareness Campaign

HARRISBURG, Pa., June 29, 2016 /PRNewswire-USNewswire/ -- The Pennsylvania Department of Health today announced the launch of the commonwealth's new Zika Virus Prevention and Awareness Campaign. The c...

Epic Health Services CEO Chris Roussos Named EY Entrepreneur of the Year® 2016 Health Winner in the Southwest

DALLAS, June 29, 2016 /PRNewswire/ -- Epic Health Services Inc., a portfolio company of Webster Capital and Dallas-based provider of pediatric skilled nursing, therapy, developmental, enteral and...

UMN Pharma Joins Protein Sciences' International Zika Vaccine Consortium

MERIDEN, Conn. and PEARL RIVER, N.Y., June 29, 2016 /PRNewswire/ -- USA and Japan -- Protein Sciences Corporation, manufacturer of Flublok® influenza vaccine, and UMN Pharma Inc. (Akita, Aki...

Fourth microbiome R & D and Business collaboration forum USA

The fourth Microbiome R&D and Business Collaboration Forum: USA will be held on the 3rd and 4th of October in La Jolla, San Diego. An increasing focus on healthy living, coupled with signs th...

SpeeDx Receives CE-IVD Mark for PlexPCR(TM) HSV-1&2, VZV

SYDNEY, AUSTRALIA -- (Marketwired) -- 06/29/16 -- SpeeDx Pty., Ltd. announced today it has received CE-IVD marking for its PlexPCR™ HSV-1&2, VZV multiplex qPCR kit. The new multiplex molecular d...

GeoVax Awarded NIH Grant for HIV Vaccine Program

ATLANTA, GA -- (Marketwired) -- 06/29/16 -- GeoVax Labs, Inc. (OTCQB: GOVX), a biotechnology company specializing in the development of human vaccines, announced today it has received a Notice of Awa...

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Companies [252 Associated Companies listed on BioPortfolio]

Promise Healthcare Group, LLC

Headquartered in Boca Raton, Florida, Promise Healthcare Group, LLC operates two operating subsidiaries, Promise Healthcare, Inc. and Success Healthcare, LLC, one of the largest l...

MSD Animal Health

For 125 years, MSD has been a global health care leader working to help the world be well. MSD Animal Health, known as Merck Animal Health in the United States and Canada, is the ...

Apria Healthcare Group Inc.

Apria is a privately held company owned by a group of investment limited partnerships managed by affiliates of Blackstone (NYSE:BX). Through its Apria Healthcare LLC operating uni...

PromptCare

PromptCare® is a leading regional provider of specialty respiratory products and infusion therapy services. Established in 1985 and headquartered in Clark, New Jersey, PromptCa...

Zoetis, Inc.

Zoetis (zô-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 60 years of experience in animal heal...

MOLOGEN AG

MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...

IDT Biologika and CMC Biologics

IDT Biologika is an innovative life science company headquartered in Dessau, Germany with extensive expertise in research, development and manufacturing of vaccines, and in additi...

BioTime, Inc. and Asterias Biotherapeutics, Inc.

Asterias Biotherapeutics, Inc. is a leading biotechnology company in the emerging field of regenerative medicine. The company’s proprietary, industry leading platforms are ba...

Inogen, Inc.

Inogen is innovation in oxygen therapy. We are a medical technology company that develops, manufactures and markets innovative oxygen concentrators used to deliver supplemental lo...

electroCore LLC

electroCore LLC, the New Jersey based bioelectric pharma company, is focused on developing non-invasive vagus nerve stimulation therapies (the gammaCore device) for the treatment ...

Clinical Trials [3404 Associated Clinical Trials listed on BioPortfolio]

Corticosteroid Mediates Acute Respiratory Distress Syndrome

It is acknowledged that IL-18, as a product of the inflammasome, is involved in host defence against viral and bacterial stimuli by modulating the immune response. The aim of this study wa...

The Effect and Mechanism of Respiratory Stimulant Doxapram on Facilitating Emergence

The current study is designed to investigate the difference of plasma orexin A levels between doxapram group and controlled group at emergence time from sevoflurane-remifentanil anesthesia...

The Predictive Effect of the Inflammatory Response on the Evacuation of Mechanical Ventilation and the Mechanism

Infection and trauma take a important role in the acute respiratory failure.There are different causes and degrees of inflammatory reaction in the critically ill patient. The inflammatory ...

PREVAIL IV: Double-Blind, Randomized, Two-Phase, Placebo-Controlled, Phase II Trial of GS-5734 to Assess the Antiviral Activity, Longer-Term Clearance of Ebola Virus, and Safety in Male Ebola Survivors With Evidence of Ebola Virus Persistence

With the unprecedented size of the recent 2014-2016 West African Ebola outbreak, the scientific community is learning a great deal about the psychological and physical consequences of Ebol...

Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary Intervention

Combination antiretroviral therapy (ART, HIV medications) dramatically increases the expected lifespan of HIV (Human Immunodeficiency Virus)infected patients; yet, the risks for cardiovasc...

Cardiopulmonary Effects of Bronchoalveolar Wash on Patients With Acute Respiratory Distress Syndrome

The acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by an inflammatory pulmonary edema, severe hypoxia and endothelial and epithelial diffuse aggression. A ...

Comparison of Respiratory Variations of the Pulse Oximetry Plethysmographic Raw Signal and Pulse Pressure During Abdominal Surgery (PLETHYSMO)

The waveform plethysmographic signal can be used to establish an index for predicting fluid responsiveness (∆POP: respiratory variation of the plethysmographic waveform of pulse oximetry...

Ultra Protective Ventilation Without Extracorporeal Circulation in Severe ARDS Patients (VT4ARDS)

Despite the use of protective ventilation, neuromuscular blocking agent and prone position, ARDS mortality remains high (30%-50%) in observational studies, and pneumothorax rate in randomi...

Position and Esophageal Pressure

Esophageal pressure measurements are used in moderate/severe Accurate Respiratory Distress SyndromeARDS patients in order to set ventilator settings. There might be variations of the measu...

PROne POsition and Volumetric CAPnography

Beneficial effect of prone position in ARDS on mortality is not linked to increase in PF ratio. It is probably due to improvement in ventilation-perfusion ratio (V/Q). Volumetric capnograp...

PubMed Articles [7186 Associated PubMed Articles listed on BioPortfolio]

Time Course of MERS-CoV Infection and Immunity in Dromedary Camels.

Knowledge about immunity to Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels is essential for infection control and vaccination. A longitudinal study of 11 dam-calf pairs sh...

Hepatitis E Virus in 3 Types of Laboratory Animals, China, 2012-2015.

We found seroprevalences for hepatitis E virus (HEV) of 7.5%, 18.5%, and 83.3% in specific pathogen-free (SPF) laboratory rabbits, monkeys, and pigs, respectively, in China. HEV RNA was detected in 4....

Aspergillus-positive lower respiratory tract samples in patients with the acute respiratory distress syndrome: a 10-year retrospective study.

The detection of Aspergillus spp. in endotracheal aspirate cultures of mechanically ventilated patients may reflect either colonization or infection. However, little is known about the prevalence and ...

Biological evaluation of N-2-hydroxypropyl trimethyl ammonium chloride chitosan as a carrier for the delivery of live Newcastle disease vaccine.

Mucosal immune system plays a very important role in antiviral immune response. We prepared Newcastle disease viruses (NDV) encapsulated in N-2-hydroxypropyl trimethyl ammonium chloride chitosan (N-2-...

Mutation in West Nile Virus Structural Protein prM during Human Infection.

A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient'...

Specificity of Dengue NS1 Antigen in Differential Diagnosis of Dengue and Zika Virus Infection.

Time Lags between Exanthematous Illness Attributed to Zika Virus, Guillain-Barré Syndrome, and Microcephaly, Salvador, Brazil.

Zika virus infection emerged as a public health emergency after increasing evidence for its association with neurologic disorders and congenital malformations. In Salvador, Brazil, outbreaks of acute ...

In vitro responses of chicken macrophage-like monocytes following exposure to pathogenic and non-pathogenic E. coli ghosts loaded with a rational design of conserved genetic materials of influenza and Newcastle disease viruses.

Avian influenza virus (AIV) and Newcastle disease virus (NDV) are two important viral diseases in the poultry industry. Therefore, new disease-fighting strategies, especially effective genetic vaccina...

Genetic detection of hantaviruses in rodents, Albania.

In order to have a first insight into the epidemiology of hantaviruses in Albania, 263 small mammals (248 rodents, 15 insectivores) were captured in 352 locations in 29 districts and tested for hantav...

Interpreting diaphragmatic movement with bedside imaging, review article.

The diaphragm is the most important muscle of respiration. At equilibrium, the load imposed on the diaphragmatic muscles from transdiaphragmatic pressure balances the force generated by diaphragmatic ...

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Medical and Biotech [MESH] Definitions

Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES.

Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.

A species of PNEUMOVIRUS causing an important respiratory infection in cattle. Symptoms include fever, conjunctivitis, and respiratory distress.

An acute inflammatory disease of the upper RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

The type species of PNEUMOVIRUS and an important cause of lower respiratory disease in infants and young children. It frequently presents with bronchitis and bronchopneumonia and is further characterized by fever, cough, dyspnea, wheezing, and pallor.

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