Respiratory syncytial virus RSV Vaccines - Biotech, Pharma and Life Science Channel

09:10 EDT 27th August 2014 | BioPortfolio

Respiratory syncytial virus (RSV) infection, which manifests primarily as bronchiolitis and/or viral pneumonia, is the leading cause of lower respiratory tract infection in infants and young children. In the US, RSV LRT infection develops annually in 4-5 million children, and more than 125,000 children are admitted per year for RSV-related illness. RSV disease is the no.1 cause of hospitalization in babies under a year of age in the US. While a monoclonal antibody is commercially available to help prevent RSV disease in infants and children at high risk for severe lung disease from RSV, a RSV vaccine still is not on the market. A number of RSV vaccine candidates have entered clinical development and further are to follow. Also, next generation antibodies against RSV with improved features are in the development pipeline as well as new therapies based on silencing RSV RNA or inhibiting key targets of the virus.

News Articles [868 Associated News Articles listed on BioPortfolio]

European Commission Approves Bristol-Myers Squibb’s Daklinza (daclatasvir) Across Multiple Genotypes for the Treatment of Chronic Hepatitis C Infection

Daklinza, when used in combination with sofosbuvir, is an all-oral, once daily regimen that yields cure rates of up to 100% Daklinza + sofosbuvir offers potential cure fo...

Rwanda Aims to Eradicate Cervical Cancer, Giving Women Hope, Reports KT Press

KIGALI, Rwanda, Aug. 27, 2014 /PRNewswire-USNewswire/ -- Seraphine Mukandutiye, 50, is a Rwandan woman with a beautiful and glowing smile. But beneath her soft heart and warm smile, lies a deadly mons...

Sinovac Announces Results of 2014 Annual General Meeting of Shareholders

BEIJING, Aug. 27, 2014 /PRNewswire/ -- Sinovac Biotech Ltd. (NASDAQ:SVA), a leading provider of biopharmaceutical products in China, today announced the results of the Company's 2014 Annual Genera...

Registered Respiratory Therapist Rainard A. Janolino, RRT, Welcomed to the Elite of Respiratory Care Professionals in Worldwide Leaders in Healthcare

The International Association of HealthCare Professionals has elected with care and attention Rainard A. Janolino, RRT, to represent respiratory care specialists in their publication Worldwide Leaders...

Registered Respiratory Therapist Mike C. Chen, RRT, Hailed for His Dedication to Excellence in Patient Care in Worldwide Leaders in Healthcare

The International Association of HealthCare Professionals has carefully selected Mike C. Chen, RRT, to represent respiratory care specialists of California in their publication Worldwide Leaders in He...

Mers CoV Virus Gene Replikins Found Conserved and Shared in Current Strains Back to 2012

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Influenza H1N1 Virus Gene Replikins Found Conserved and Shared in Current Strains Back to 1918

LONDON, Aug. 26, 2014 /PRNewswire/ -- An analysis by Replikins, Ltd. of Pubmed data of the gene structures of all Influenza H1N1 virus strains has revealed extensive conservation and sharing of s...

Ebola Virus Gene Replikins Found Conserved and Shared in All Ebola Strains Back to 1976

LONDON, Aug. 26, 2014 /PRNewswire/ -- An analysis by Replikins, Ltd. of Pubmed data of the gene structures of all Ebola strains has revealed extensive conservation and sharing of specific Repliki...

Clongen Laboratories, LLC expands tick and arthropod-borne illness testing by offering new diagnostic assays for emerging pathogens

GAITHERSBURG, Md., Aug. 26, 2014 /PRNewswire -- Clongen Laboratories, celebrating its tenth anniversary, is a leading provider of diagnostic and contract research services.  The company announced...

Over Three-Fourths of Americans Believe Childhood Vaccinations Should be Mandatory

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Events [1 Associated Events listed on BioPortfolio]

Cancer Vaccines 2014

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Companies [209 Associated Companies listed on BioPortfolio]

Appian Medical

Appian Medical is leading the way in the innovation of mobile health technologies to solve the universal need for accessible, accurate and affordable consumer-directed diagnostics...

Redbiotec

Redbiotec is a privately held Swiss biopharmaceutical company founded in 2006 and based in Zurich-Schlieren. The company uses its proprietary rePAX® co-expression tec...

Carex Health Brands and Roscoe Medical

Roscoe Medical, headquartered in Strongsville, Ohio, is a major manufacturer and distributor of innovative healthcare products that promote independence and better living in the h...

Kala Pharmaceuticals Inc.

Kala Pharmaceuticals, Inc. is advancing innovative treatments for ocular diseases addressing significant needs in both front and back of the eye based on the company’s propri...

Agenus, Inc.

Agenus is an immuno-oncology company developing a portfolio of checkpoint modulators (CPMs), heat shock protein vaccines and adjuvants. Agenus’ checkpoint modulator programs...

Forest Laboratories, Inc. and Furiex Pharmaceuticals, Inc.

Forest Laboratories (NYSE: FRX) is a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market. Forest markets a portfolio of branded...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

Carex Health Brands & Roscoe Medical

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Allegro Diagnostics Corp.

Allegro Diagnostics’ molecular testing platform utilizes gene expression of normal epithelial cells in the respiratory tract to detect early signs of lung cancer and diseases...

PaxVax Inc.

PaxVax is a privately held specialty vaccine company founded in 2007. PaxVax is focused on traveler vaccines with an emerging pipeline in biodefense coupled with a social mission...

Clinical Trials [2346 Associated Clinical Trials listed on BioPortfolio]

Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults

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An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

Effect of Gastric Lavage in Preventing Feeding Problems in Babies Born With Meconium Stained Amniotic Fluid

The purpose of the study is to evaluate the role of gastric lavage in preventing feeding problems in babies born through meconium stained amniotic fluid. It is a routine practice in many h...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

Safety, Pharmacokinetics, and Pharmacodynamics of MK-8408 in Participants With Hepatitis C Infection (MK-8408-003)

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Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination and Sofosbuvir + Ribavirin for Subjects With Chronic Hepatitis C Virus (HCV) and Inherited Bleeding Disorders

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Pilot Study to Assess Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-dose Combination in Treatment Experienced Subjects With Hepatitis C Virus (HCV) Genotype 1 - HIV Co-infection

Aim of the study is to assess the efficacy and safety of 24 weeks of oral Sofosbuvir/Ledipasvir fixed-dose combination (FDC) in subjects with HCV genotype 1 infection and HIV co-infection,...

Study of Respiratory Physiology During High Flow Nasal Cannula Treatment in Preterm Neonates.

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Mesenchymal Stem Cell in Patients With Acute Severe Respiratory Failure

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iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma/VEGAS

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PubMed Articles [7419 Associated PubMed Articles listed on BioPortfolio]

Effect and mechanisms of curdlan sulfate on inhibiting HBV infection and acting as an HB vaccine adjuvant.

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A comparison of the thermal inactivation kinetics of human norovirus surrogates and hepatitis A virus in buffered cell culture medium.

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What Is Health Communication and How Does It Affect the HIV/AIDS Continuum of Care? A Brief Primer and Case Study From New York City.

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Network-based vaccination improves prospects for disease control in wild chimpanzees.

Many endangered wildlife populations are vulnerable to infectious diseases for which vaccines exist; yet, pragmatic considerations often preclude large-scale vaccination efforts. These barriers could...

Update on the Management of Neonatal Sepsis in Horses.

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MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants.

New alginic acid-atenolol microparticles for inhalatory drug targeting.

The inhalatory route allows drug delivery for local or systemic treatments in a noninvasively way. The current tendency of inhalable systems is oriented to dry powder inhalers due to their advantages...

Prevention of respiratory infections at day care centers: recommendations and systematic review of the evidence.

Introduction. Attending a day care center is a risk factor for respiratory infections. The objective of this study is to review which nonspecific prevention measures are recommended for day care cente...

Association between infection of hepatitis B virus and onset risk of B-cell non-Hodgkin's lymphoma: a systematic review and a meta-analysis.

Whether an association between hepatitis B virus (HBV) infection and B-cell non-Hodgkin's lymphoma (B-NHL) risk exists is an open question. In order to provide quantification of the issue, we carried...

Response to the letter 'On noting the achievements and future potential of data-driven gating for respiratory motion correction in PET imaging'

Medical and Biotech [MESH] Definitions

Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES.

Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.

A species of PNEUMOVIRUS causing an important respiratory infection in cattle. Symptoms include fever, conjunctivitis, and respiratory distress.

An acute inflammatory disease of the upper RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

The type species of PNEUMOVIRUS and an important cause of lower respiratory disease in infants and young children. It frequently presents with bronchitis and bronchopneumonia and is further characterized by fever, cough, dyspnea, wheezing, and pallor.

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Infectious diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi; the diseases can be spread, directly or indirectly, from one person to another. Zoonotic diseases are infectious diseases of animals that can caus...

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