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Respiratory syncytial virus RSV Vaccines - Biotech, Pharma and Life Science Channel

04:46 EDT 24th July 2016 | BioPortfolio

Respiratory syncytial virus (RSV) infection, which manifests primarily as bronchiolitis and/or viral pneumonia, is the leading cause of lower respiratory tract infection in infants and young children. In the US, RSV LRT infection develops annually in 4-5 million children, and more than 125,000 children are admitted per year for RSV-related illness. RSV disease is the no.1 cause of hospitalization in babies under a year of age in the US. While a monoclonal antibody is commercially available to help prevent RSV disease in infants and children at high risk for severe lung disease from RSV, a RSV vaccine still is not on the market. A number of RSV vaccine candidates have entered clinical development and further are to follow. Also, next generation antibodies against RSV with improved features are in the development pipeline as well as new therapies based on silencing RSV RNA or inhibiting key targets of the virus.

News Articles [905 Associated News Articles listed on BioPortfolio]

Media Briefing and Q&A with Leading Researchers on Zika Virus and Diagnostic Testing

WASHINGTON, July 22, 2016 /PRNewswire-USNewswire/ -- Leading researchers will discuss the global impact and role of diagnostic testing for the Zika virus as well as how the timing of infection affects...

Continuous Peripheral Nerve Block Catheters Market: Non-stimulating Catheter Systems Will Continue to Gain Traction

VALLEY COTTAGE, New York, July 22, 2016 /PRNewswire/ -- Continuous peripheral nerve block catheters are gaining traction in the healthcare sector as an effective analgesic for pain management. The gl...

Human medicines European public assessment report (EPAR): Imvanex, modified vaccinia Ankara virus, Revision: 8, Authorised

Philips SimplyGo Mini portable oxygen concentrator conforms to FAA standards, now available for on board aircraft use

AMSTERDAM, July 21, 2016 /PRNewswire/ -- Philips Respironics, a division of Royal Philips (NYSE: PHG, AEX: PHIA), announced today that their SimplyGo Mini portable oxygen concentrator (POC) confo...

Gillette expert changes travel plans amid Zika concerns, cautions Olympic travelers

ST. PAUL, Minn., July 21, 2016 /PRNewswire-USNewswire/ -- A Gillette Children's Specialty Healthcare physician is cautioning those who are traveling to the Olympics in Rio to take extra care and ...

Philips' Care Orchestrator to connect Trilogy ventilators to advance care for patients with COPD and other respiratory conditions

AMSTERDAM, July 21, 2016 /PRNewswire/ -- Philips Respironics, a business of Royal Philips (NYSE: PHG, AEX: PHIA), today announced that its Trilogy family of portable ventilators, the most widely ...

DNAtrix Announces Successful Intratumoral Delivery of DNX-2401 via Alcyone's MEMS Cannula for the Targeted Treatment of Recurrent Glioblastoma

HOUSTON and LOWELL, Mass., July 21, 2016 /PRNewswire/ -- DNAtrix, a clinical stage, biotechnology company developing virus-driven immunotherapies for cancer, announced the successful intratumoral admi...

Concern about Zika Virus Reaches its Highest Point Among US OB/GYNs, According to New Data from InCrowd

BOSTON, July 21, 2016 /PRNewswire/ -- US OB/GYNs concerns about the Zika virus continue to be on the rise, with more adoption of hospital protocols and automatic testing for at-risk women through...

US Animal Vaccines Industry Key Growth Factors, Trends, Size, Demand and Opportunities

PORTLAND, Oregon, July 21, 2016 /PRNewswire/ -- The US Animal Vaccines Industry 2015 Market Research Report is a professional and in-depth study on the current state of the Animal Vaccines industry. ...

GSK ships 2016-17 seasonal influenza vaccines for US market

PHILADELPHIA, July 20, 2016 /PRNewswire/ -- GSK [LSE/NYSE: GSK] announced today it has begun shipping quadrivalent vaccine doses to US healthcare providers, following licensing and lot-rele...

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Companies [252 Associated Companies listed on BioPortfolio]

Promise Healthcare Group, LLC

Headquartered in Boca Raton, Florida, Promise Healthcare Group, LLC operates two operating subsidiaries, Promise Healthcare, Inc. and Success Healthcare, LLC, one of the largest l...

MSD Animal Health

For 125 years, MSD has been a global health care leader working to help the world be well. MSD Animal Health, known as Merck Animal Health in the United States and Canada, is the ...

Apria Healthcare Group Inc.

Apria is a privately held company owned by a group of investment limited partnerships managed by affiliates of Blackstone (NYSE:BX). Through its Apria Healthcare LLC operating uni...

PromptCare

PromptCare® is a leading regional provider of specialty respiratory products and infusion therapy services. Established in 1985 and headquartered in Clark, New Jersey, PromptCa...

Zoetis, Inc.

Zoetis (zô-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 60 years of experience in animal heal...

MOLOGEN AG

MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...

IDT Biologika and CMC Biologics

IDT Biologika is an innovative life science company headquartered in Dessau, Germany with extensive expertise in research, development and manufacturing of vaccines, and in additi...

BioTime, Inc. and Asterias Biotherapeutics, Inc.

Asterias Biotherapeutics, Inc. is a leading biotechnology company in the emerging field of regenerative medicine. The company’s proprietary, industry leading platforms are ba...

Inogen, Inc.

Inogen is innovation in oxygen therapy. We are a medical technology company that develops, manufactures and markets innovative oxygen concentrators used to deliver supplemental lo...

electroCore LLC

electroCore LLC, the New Jersey based bioelectric pharma company, is focused on developing non-invasive vagus nerve stimulation therapies (the gammaCore device) for the treatment ...

Clinical Trials [3461 Associated Clinical Trials listed on BioPortfolio]

Investigation Into the Infectivity Levels of Human Papilloma Virus (HPV) in Tonsillar Tissue

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Non-rebreather at Flush Rate Compared to Bag Valve Mask With Assist

This crossover investigation enrolls healthy volunteers and compares the exhaled oxygen content (FeO2) between the non-rebreather mask at the flush rate and a bag-valve-mask device at the ...

NIPPV Versus Bi-level Nasal Continuous Positive Airway Pressure Following Extubation

Mechanical ventilation is important in the care of preterm infants with respiratory failure, but may be associated with lung injury. Efforts are needed to avoid or minimize the use of mech...

Calibration of a New Reflectance Oximeter.

This study is about the development of a new medical device for the monitoring of of sleep disordered breathing. This device is developed by the CEA-LETI-LE2S and will be composed of an ox...

Effects of Dexmedetomidine on Respiratory Function and Inflammatory Responses in Patient With Sepsis Undergoing Cleaning Focus of Infection

The purpose of this study is to assess the efficacy of dexmedetomidine on lung protection in patient with sepsis undergoing cleaning focus of infection.

Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA085-00-VP, in Healthy Adults

Background: The Zika virus is passed to humans by infected mosquitos. It usually causes fever, rash, joint pain, and red eyes. Recently, some cases of microcephaly (abnormally small head)...

A Study to Evaluate Safety, Immunogenicity, and Lot-to-Lot Consistency of H5N1 Subunit Influenza Virus Vaccine in Healthy Adult Subjects ≥18 Years of Age

This Phase 3 study evaluates the safety, immunogenicity and lot-to lot consistency of 3 lots of aH5N1c vaccine for pandemic avian influenza, in approximately 2394 healthy adults ≥18 year...

Acceptable Range of Inspiratory Effort During Mechanical Ventilation

Partially assisted mechanical ventilation is ideally titrated to maintain adequate inspiratory muscle activity (i.e. preventing disuse atrophy) while avoiding excessive (i.e. fatiguing) in...

Employing End Tidal Capnography in Continuous Flow Ventricular Assist Device Patients

The purpose of this study is to explore how the End Tidal Carbon Dioxide monitoring via nasal cannula (ETCO2-NC) device may allow for earlier detection of respiratory complications. This d...

VircapSeq Virus Detection in Sézary Syndrome

This study will be using this technique, called "VirCapSeq-VERT" to analyze the white blood cells of patients with Sézary syndrome. This could provide the foundation for future studies lo...

PubMed Articles [7157 Associated PubMed Articles listed on BioPortfolio]

Time Course of MERS-CoV Infection and Immunity in Dromedary Camels.

Knowledge about immunity to Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels is essential for infection control and vaccination. A longitudinal study of 11 dam-calf pairs sh...

Hepatitis E Virus in 3 Types of Laboratory Animals, China, 2012-2015.

We found seroprevalences for hepatitis E virus (HEV) of 7.5%, 18.5%, and 83.3% in specific pathogen-free (SPF) laboratory rabbits, monkeys, and pigs, respectively, in China. HEV RNA was detected in 4....

Aspergillus-positive lower respiratory tract samples in patients with the acute respiratory distress syndrome: a 10-year retrospective study.

The detection of Aspergillus spp. in endotracheal aspirate cultures of mechanically ventilated patients may reflect either colonization or infection. However, little is known about the prevalence and ...

Culex pipiens and Aedes triseriatus Mosquito Susceptibility to Zika Virus.

Biological evaluation of N-2-hydroxypropyl trimethyl ammonium chloride chitosan as a carrier for the delivery of live Newcastle disease vaccine.

Mucosal immune system plays a very important role in antiviral immune response. We prepared Newcastle disease viruses (NDV) encapsulated in N-2-hydroxypropyl trimethyl ammonium chloride chitosan (N-2-...

Mutation in West Nile Virus Structural Protein prM during Human Infection.

A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient'...

Specificity of Dengue NS1 Antigen in Differential Diagnosis of Dengue and Zika Virus Infection.

Inactivation and Environmental Stability of Zika Virus.

Frequency of West Nile Virus Infection in Iranian Blood Donors.

West Nile virus (WNV) can be transmitted by blood transfusions and organ transplants. This study was a retrospective study which was performed in Blood Transfusion Center to evaluate the WNV infection...

Transfusion Related Acute Lung Injury (TRALI): A Single Institution Experience of 15 Years.

Transfusion related acute Lung injury (TRALI) though a serious blood transfusion reaction with a fatality rate of 5-25 % presents with acute respiratory distress with hypoxaemia and noncardiac pulmon...

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Medical and Biotech [MESH] Definitions

Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES.

Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.

A species of PNEUMOVIRUS causing an important respiratory infection in cattle. Symptoms include fever, conjunctivitis, and respiratory distress.

An acute inflammatory disease of the upper RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

The type species of PNEUMOVIRUS and an important cause of lower respiratory disease in infants and young children. It frequently presents with bronchitis and bronchopneumonia and is further characterized by fever, cough, dyspnea, wheezing, and pallor.

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