Respiratory syncytial virus RSV Vaccines - Biotech, Pharma and Life Science Channel

00:04 EDT 28th May 2015 | BioPortfolio

Respiratory syncytial virus (RSV) infection, which manifests primarily as bronchiolitis and/or viral pneumonia, is the leading cause of lower respiratory tract infection in infants and young children. In the US, RSV LRT infection develops annually in 4-5 million children, and more than 125,000 children are admitted per year for RSV-related illness. RSV disease is the no.1 cause of hospitalization in babies under a year of age in the US. While a monoclonal antibody is commercially available to help prevent RSV disease in infants and children at high risk for severe lung disease from RSV, a RSV vaccine still is not on the market. A number of RSV vaccine candidates have entered clinical development and further are to follow. Also, next generation antibodies against RSV with improved features are in the development pipeline as well as new therapies based on silencing RSV RNA or inhibiting key targets of the virus.

News Articles [821 Associated News Articles listed on BioPortfolio]

Agenus Announces Closing of Public Offering and Exercise in Full of Underwriters’ Option to Purchase Additional Shares of Common Stock

Agenus Inc. (NASDAQ: AGEN), an immunology company developing innovative treatments for cancers and other diseases, today announced the closing of its public offering of 12,650,000...

Modified herpes virus 'could combat skin cancer'

"Patients with aggressive skin cancer have been treated successfully using a drug based on the herpes virus," The Guardian reports. A new study suggests a novel form of immunotherapy could b...

Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables

SINGAPORE, LONDON and NEW YORK, May 27, 2015 /PRNewswire/ -- -http://www.abmrg.com/Indonesia-Respiratory-Devices-and-Respiratory-Diagnostics-Market-through-2020---Detailed-analysis-of-Hospital-and-Re...

BPSA's 5th Annual Summit to Provide '2020 Vision' for Single-Use Technologies

WASHINGTON, May 27, 2015 /PRNewswire-USNewswire/ -- The Bio-Process Systems Alliance (BPSA) is pleased to announce the 5th Annual International Single-Use Summit (ISUS 2015) will be held July 13-15, 2...

Nurtur's Asthma Management Program Wins Award from Dorland Health

FARMINGTON, Conn., May 27, 2015 /PRNewswire/ -- Nurtur Health, Inc. (Nurtur), a wholly owned subsidiary of Centene Corporation (NYSE: CNC), was recently honored by Dorland Health's Case in Point ...

GeoVax to Present at the LD Micro Invitational Conference

ATLANTA, GA -- (Marketwired) -- 05/27/15 -- GeoVax Labs, Inc. (OTCQB: GOVX), a biotechnology company developing innovative human vaccines against Ebola virus and HIV using its novel platform technolo...

Study Identifies Ebola Virus's Achilles' Heel

BRONX, N.Y., May 26, 2015 /PRNewswire-USNewswire/ -- An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research I...

Hill-Rom to Participate in the Goldman Sachs 36th Annual Global Healthcare Conference

CHICAGO, May 26, 2015 /PRNewswire/ -- Hill-Rom Holdings, Inc., (NYSE: HRC) invites you to listen to a management presentation at the Goldman Sachs 36th Annual Global Healthcare Conference on June...

AlphaVax, Inc. - Product Pipeline Review - 2015

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Events [1 Associated Events listed on BioPortfolio]

Allergies

SMi presents the 2nd annual conference on… Allergies 8th & 9th July 2015 www.allergies-event.com/BioPortfolio

Companies [226 Associated Companies listed on BioPortfolio]

Center for Infectious Disease Research

Center for Infectious Disease Research is the largest independent, non-profit organization in the U.S. focused solely on infectious disease research. Our mission is to make transf...

ResMed

ResMed (NYSE: RMD and ASX: RMD.AX) is a leading developer, manufacturer and marketer of products for the screening, treatment and long-term management of sleep-disordered breathing (SDB) and other res...

Aduro BioTech, Inc.

Aduro BioTech is a clinical-stage immunotherapy company with a platform technology for therapeutic and prophylactic vaccines for cancer and infectious diseases. The platform of at...

Madison Vaccines Incorporated

Wisconsin-based MVI is developing two plasmid DNA vaccines to treat men with prostate cancer. MVI has licensed patented technologies that were developed in the laboratory of Dr. D...

Zambon S.p.A.

Zambon is a leading Italian pharmaceutical and fine-chemical multinational company that has earned a strong reputation over the years for high quality products and services. Zambo...

RxC International

RxC International is a life sciences management consulting firm specializing in corporate strategy, new product development, and commercialization. RxC International brings strate...

Synexus

Synexus® is the world’s largest multi-national company dedicated to the recruitment and running of clinical trials at its own research centres across the globe on behalf o...

Global Virus Network

The Global Virus Network (GVN) is an independent organization comprised of leading medical virologists from Argentina, Australia, Canada, China, Germany, India, Ireland, Israel, I...

Seattle Biomedical Research Institute

Seattle Biomedical Research Institute is the largest independent, non-profit organization in the United States focused solely on infectious disease research. The mission of SBRI's nearly 200 employee...

Sunovion Pharmaceuticals, Inc.

Sunovion is a leading pharmaceutical company dedicated to discovering, developing and commercializing therapeutic products that advance the science of medicine in the Psychiatry &...

Clinical Trials [2676 Associated Clinical Trials listed on BioPortfolio]

Dexmedetomidine in Mechanically Ventilated Neonates With Single-Organ Respiratory Failure.

Clinical experience with dexmedetomidine in the paediatric population is limited. Critical illness can affect drug pharmacokinetics and -dynamics; the investigators cannot simply extrapola...

Respiratory Muscle Function in Untreated X-Linked Myotubular Myopathy (XLMTM)

This study is a longitudinal study evaluating the severity and progression of respiratory muscle function in patients with X-Linked Myotubular Myopathy (XLMTM) aged 0-14.

Morphofunctional Lung Analysis by Positron Emission Tomography

Patients affected by acute lung injury-acute respiratory distress syndrome (ALI-ARDS) undergo a positron emission tomography (PET) scan in order to analyse lung function.

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination (FDC) for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic HCV Infection

This study will evaluate the safety, tolerability, and antiviral efficacy of ledipasvir/sofosbuvir (LDV/SOF) fixed-dose combination (FDC) for 12 or 24 weeks in adults with chronic genotype...

Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Regimen Versus Boosted Protease Inhibitor (bPI) Along With Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) Regimen in Virologically-Suppres

The purpose of this study is to demonstrate non-inferiority in efficacy while switching to a once-daily single-tablet regimen containing darunavir (DRV)/ cobicistat (COBI)/ emtricitabine (...

Point of Care Ultrasonography

This is a Prospective, Double-center, randomized clinical trial. The purpose of the trial is to evaluate the benefit of adding POC US to the management of inpatients admitted to the intern...

Four-Drug Combination Therapy With Zidovudine, Lamivudine, 1592U89 (Abacavir), and 141W94 (Amprenavir) in HIV-Infected Patients

The purpose of this study is to see if the multidrug combination of zidovudine (ZDV), lamivudine (3TC), 1592U89 (abacavir [ABC]), and 141W94 (amprenavir [APV]) is a safe and effective trea...

Smoking Cessation for HIV/AIDS Patients

The goal of this research study is to look at treatments that may help individuals who have HIV/AIDS to stop smoking.

Effects of Bortezomib-Based Therapy on Cellular Immunity and Response to DC/Myeloma Fusion Vaccines in Vitro

The purpose of this study is to better understand what effects Bortezomib, a drug used for multiple myeloma therapy, has on the immune system.

Genetically Engineered HSV-1 Phase 1 Study

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PubMed Articles [7577 Associated PubMed Articles listed on BioPortfolio]

The stability analysis of an SVEIR model with continuous age-structure in the exposed and infectious classes.

In this paper, an Susceptible-Vaccines-Exposed-Infectious-Recovered model with continuous age-structure in the exposed and infectious classes is investigated. These two ages are assumed to have arbitr...

Partial and total C-6 oxidation of gelling carrageenans. Modulation of the antiviral activity with the anionic character.

The optimal conditions for the full C-6 oxidation of κ- and ι-carrageenans using (2,2,6,6-tetramethylpiperidinyl)oxy (TEMPO) in the presence of sodium hypochlorite and sodium bromide were assessed. ...

Immunochromatographic assay for quantitative and sensitive detection of hepatitis B virus surface antigen using highly luminescent quantum dot-beads.

Hepatitis B virus infection is one of the major causes of hepatitis, liver cirrhosis and liver cancer. In this study, we used highly luminescent quantum dot-beads (QBs) as signal amplification probes ...

Global stability of an age-structured virus dynamics model with Beddington-DeAngelis infection function.

In this paper, we study an age-structured virus dynamics model with Beddington-DeAngelis infection function. An explicit formula for the basic reproductive number R0 of the model is obtained. We inves...

Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics.

The past century's description of oncolytic virotherapy as a cancer treatment involving specially-engineered viruses that exploit immune deficiencies to selectively lyse cancer cells is no longer adeq...

Nasopharyngeal Carcinoma.

Nasopharyngeal carcinoma is uncommon in the United States, with only 0.2 to 0.5 cases per 100,00 people; this is in contrast to southern China and Hong Kong, where the incidence is 25 to 50 per 100,00...

Cancer of the Oropharynx.

The oropharynx has a crucial role in swallowing because of the surrounding constrictor musculature, need for mobility and pliability, and proximity of the base of tongue to the larynx. Human papilloma...

Dextrans produced by lactic acid bacteria exhibit antiviral and immunomodulatory activity against salmonid viruses.

Viral infections in the aquaculture of salmonids can lead to high mortality and substantial economic losses. Thus, there is industrial interest in new molecules active against these viruses. Here we d...

Rapid baculovirus titration assay based on viable cell side scatter (SSC).

The baculovirus expression system is one of the most powerful tools for the production of recombinant proteins on both laboratory and industrial scales. Multiplicity of infection (MOI) is the crucial ...

Analytical methods for assessing metal bioaccessibility in airborne particulate matter: A scoping review.

In contrast to the existence of standardized methods to assess metal bioaccessibility via the gastrointestinal route, there are no widely-accepted, established in vitro testing protocols to measure el...

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Medical and Biotech [MESH] Definitions

Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES.

Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.

A species of PNEUMOVIRUS causing an important respiratory infection in cattle. Symptoms include fever, conjunctivitis, and respiratory distress.

An acute inflammatory disease of the upper RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

The type species of PNEUMOVIRUS and an important cause of lower respiratory disease in infants and young children. It frequently presents with bronchitis and bronchopneumonia and is further characterized by fever, cough, dyspnea, wheezing, and pallor.

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Respiratory
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Respiratory tract infections (RTIs) are any infection of the sinuses, throat, airways or lungs.  They're usually caused by viruses, but they can also be caused by bacteria. Respiratory tract infections are believed to be one of the main rea...

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