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Respiratory syncytial virus RSV Vaccines - Biotech, Pharma and Life Science Channel

03:14 EDT 16th April 2014 | BioPortfolio

Respiratory syncytial virus (RSV) infection, which manifests primarily as bronchiolitis and/or viral pneumonia, is the leading cause of lower respiratory tract infection in infants and young children. In the US, RSV LRT infection develops annually in 4-5 million children, and more than 125,000 children are admitted per year for RSV-related illness. RSV disease is the no.1 cause of hospitalization in babies under a year of age in the US. While a monoclonal antibody is commercially available to help prevent RSV disease in infants and children at high risk for severe lung disease from RSV, a RSV vaccine still is not on the market. A number of RSV vaccine candidates have entered clinical development and further are to follow. Also, next generation antibodies against RSV with improved features are in the development pipeline as well as new therapies based on silencing RSV RNA or inhibiting key targets of the virus.

News Articles [668 Associated News Articles listed on BioPortfolio]

Zogenix Announces Ruling Preventing the Implementation of Massachusetts Governor's Order that Prevented Access to Zohydro™ ER

SAN DIEGO, April 15, 2014 /PRNewswire/ -- Zogenix, Inc. (Nasdaq: ZGNX), a pharmaceutical company developing and commercializing products for the treatment of pain-related and central nervous syst...

DEP Awards 26 Counties Nearly $2.1 Million in West Nile Virus Grants

HARRISBURG, Pa., April 15, 2014 /PRNewswire-USNewswire/ -- The Department of Environmental Protection (DEP) today announced it is awarding nearly $2.1 million in West Nile Virus (WNV) Control Program...

Basketball Hall of Famer Nancy Lieberman Teams Up with New Nasacort® Allergy 24HR to Help Allergy Sufferers Put the Full 'Cort Press on Nasal Allergy Symptoms

CHATTANOOGA, Tenn., April 15, 2014 /PRNewswire/ -- Nancy Lieberman, basketball hall of famer, coach and mom, has teamed up with Sanofi's consumer healthcare division Chattem Inc. to introduce a n...

Banfield Pet Hospital's State of Pet Health™ 2014 Report Shows Increase in Infectious Diseases in Dogs and Cats

PORTLAND, Ore., April 15, 2014 /PRNewswire/ -- Banfield Pet Hospital®, the world's largest veterinary practice, released its State of Pet Health™ 2014 Report today, revealing a staggering 4...

Prosonix and Mylan Enter Into Global Licensing Agreement for Generic Versions of Inhaled Respiratory Products Flixotide® and Flovent®

OXFORD, England and PITTSBURGH, Pennsylvania, April 15, 2014 /PRNewswire/ -- Prosonix, an innovative speciality pharmaceutical company developing a portfolio of inhaled Respiratory Medicines by Desig...

Mucosis Announces a Strategic Partnership with Changchun Bcht Biotechnology of China and Raises ...

Groningen, the Netherlands, April 15, 2014 / B3C newswire / - Biotechnology company Mucosis B.V. today announced that it entered into a long-term collaboration and license agreement with China-based...

Professor Raymond Schinazi Joins Board of reViral as Non-executive Director

LONDON, April 15, 2014 /PRNewswire/ -- reViral, an antiviral drug discovery and development company, focused on diseases caused by the respiratory syncytial virus (RSV), today announced the appointme...

Dynavax Initiates Phase 3 Study of HEPLISAV-B(TM)

BERKELEY, CA -- (Marketwired) -- 04/15/14 -- Dynavax Technologies Corporation (NASDAQ: DVAX) today announced initiation of a new phase 3 clinical trial of HEPLISAV-B, its investigational adult hepati...

Cocrystal Pharma, Inc. Announces Stock Symbol Change from BZNE to COCP

BOTHELL, WA--(Marketwired - April 15, 2014) - Cocrystal Pharma, Inc. (the "Company") (OTCQB: COCP), announced today that, effective April 15, 2014, the Company's stock began trading u...

Quidel to Hold First Quarter 2014 Financial Results Conference Call on April 23, 2014

SAN DIEGO, CA -- (Marketwired) -- 04/15/14 -- Quidel Corporation (NASDAQ: QDEL), a provider of rapid diagnostic testing solutions, cellular-based virology assays and molecular diagnostic systems, wi...

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Companies [195 Associated Companies listed on BioPortfolio]

Dimension Therapeutics

Dimension Therapeutics is a gene therapy company focused on developing novel therapies to treat rare diseases. Launched by Fidelity Biosciences in 2013, the Dimension team compris...

SynteractHCR

SynteractHCR is a full-service contract research organization with a successful two-decade track record supporting biotechnology, medical device and pharmaceutical companies in al...

Promise Healthcare

Headquartered in Boca Raton, Florida, Promise Healthcare, Inc. (www.promisehealthcare.com) is one of the largest long-term acute care (LTAC) hospital organizations in the country....

Allegro Diagnostics Corp.

Allegro Diagnostics’ molecular testing platform utilizes gene expression of normal epithelial cells in the respiratory tract to detect early signs of lung cancer and diseases...

Carex Health Brands & Roscoe Medical

Roscoe Medical, headquartered in Strongsville, Ohio, is a major manufacturer and distributor of innovative healthcare products that promote independence and better living in the h...

Voyager Therapeutics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for fatal and debilitating diseases of the central nervous system (CNS). Voyager is committed to...

TKL Research, Inc.

TKL Research is a full-service, international CRO offering complete Phase 1-4 clinical trial services, often in enrollment-driven therapeutic areas. The company has a solid reputa...

Advanced BioScience Laboratories, Inc. (ABL)

Profectus is a clinical-stage biotechnology company developing novel vaccines to prevent and treat major chronic viral infectious diseases and associated cancers for which standar...

Promise Healthcare, Inc.

Based in Boca Raton, Florida, Promise Healthcare is one of the largest long-term acute care (LTAC) hospital organizations in the country. With more than 2,000 staff members and 13...

Barlow Respiratory Hospital

Barlow Respiratory Hospital is the only not-for-profit, long-term, acute care respiratory hospital in Southern California. We specialize in caring for critically ill, complex pati...

Clinical Trials [2340 Associated Clinical Trials listed on BioPortfolio]

An Open Label Pharmacokinetic, Safety And Efficacy Study Of Maraviroc In Combination With Background Therapy For The Treatment Of HIV-1 Infected, CCR5 -Tropic Children

The primary purpose of this study is to determine the pharmacokinetic properties (what the body does to maraviroc) and to determine a suitable dosing schedule of maraviroc in HIV-1 infecte...

Study to Evaluate the Safety and Immunogenicity of Poly ICLC (Hiltonol) in Healthy Volunteers

Vaccines induce protective immunity against numerous infectious diseases. However, current vaccines have limited efficacy against challenging infections like tuberculosis, malaria and HIV....

Genetic Study of Peginterferon Treatment in Hepatitis B Patients: The GIANT-B Study

Background and rationale Chronic hepatitis B is the most common cause of liver cirrhosis and hepatocellular carcinoma worldwide.(1) Antiviral therapy with oral nucleoside analogs and inter...

Study to Assess the Seroprevalence of Anti-Tat Antibodies in HIV-infected Patients

Tat is a key HIV regulatory protein produced very early after infection, prior to virus integration, and necessary for viral gene expression, cell-to-cell virus transmission and disease pr...

Observational Study of Nevirapine Extended Release in Human Immunodeficiency Virus (HIV) Patients in Daily Clinical Practice

This Post Marketing Surveillance study will be performed as an open-label, prospective, non-interventional, uncontrolled study in Human immunodeficit Virus-1 (HIV-1) infected patients. Dat...

A Multiple Dose Study of MK-5172 in Hepatitis C-Infected Participants (MK-5172-010)

This study will compare hepatic pharmacokinetics (PK) derived from liver tissue to plasma PK after administration of MK-5172 to participants with chronic hepatitis C virus (HCV) infection....

Study of the Safety and Immunogenicity of a Novel H5N1 Influenza Vaccine in Healthy Adults Age 18-49

The purpose of this study is to test an investigational vaccine known as "VAX161C." An "investigational" vaccine is one that is not licensed for commercial use in the by the United States...

Safety Study of GNbAC1 in Multiple Sclerosis Patients

The purpose of this study is to assess the safety and tolerability of single ascending doses, as well as of repeated administrations of GNbAC1 in MS patients. Scientific research has show...

Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy

Background: - Drugs given to treat cancer (chemotherapy) can weaken the human immune system. But it can also become weaker because of aging. Interleukin (IL)-7, a molecule produced natura...

Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure

The investigators in this study are concerned about the harmful effects of oxygen exposure in newborn infants, particularly at high concentrations. Inhaled nitric oxide (iNO) is an FDA ap...

PubMed Articles [4938 Associated PubMed Articles listed on BioPortfolio]

Aspirin Desensitization: Useful Treatment for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in Aspirin-Exacerbated Respiratory Disease (AERD)?

Aspirin intolerance syndrome is due to disturbances in the arachidonic acid metabolism implicating both the lipoxygenase and cyclooxygenase pathways. This results in imbalances of eicosanoid, leukotri...

Management of chronic rhinosinusitis in asthma patients: is there still a debate?

The united airway concept in which upper and lower respiratory conditions are present in one patient requires special consideration. There is some evidence linking chronic rhinosinusitis and asthma, b...

Good's Syndrome, CVID, and Selective Antibody Deficiency in Patients with Chronic Rhinosinusitis.

Good's syndrome and common variable immune deficiency (CVID) are associated with chronic rhinosinusitis. Good's syndrome is characterized by hypogammaglobulinemia, B-cell depletion, variable defects i...

Engaging adaptive immunity with biomaterials.

Adaptive immune responses, characterized by T cells and B cells engaging and responding to specific antigens, can be raised by biomaterials containing proteins, peptides, and other biomolecules. How d...

Depuration kinetics of hepatitis A virus in clams.

The efficacy and dynamic of depuration for the removal of hepatitis A virus (HAV) contamination were evaluated under experimental conditions using Manila clams previously subjected to bioaccumulation...

Adaptive Responses of Mitochondria to Mild Copper Deprivation Involve Changes in Morphology, OXPHOS Remodeling and Bioenergetics.

Copper is an essential cofactor of complex IV of the electron transfer chain, and it is directly involved in the generation of mitochondrial membrane potential. Its deficiency induces the formation of...

Current treatment and management of dystrophinopathies.

• Duchenne muscular dystrophy (DMD), the most common and severe type of dystrophinopathy, is a progressive disease affecting primordially skeletal and cardiac muscle. A coordinated multidisciplinary...

Reply to "CD8+ T Cells Are Essential for Controlling Acute Friend Virus Infection in C57BL/6 Mice".

Novel cell-based hepatitis C virus infection assay for quantitative high-throughput screening of anti-hepatitis C virus compounds.

Understanding HIV Compartments and Reservoirs.

The spectrum of HIV-1 cellular reservoirs is highly diversified, and their role varies according to the milieu of the anatomical sites in which the virus replicates. In this light, mechanisms underlyi...

Medical and Biotech [MESH] Definitions

Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES.

Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.

A species of PNEUMOVIRUS causing an important respiratory infection in cattle. Symptoms include fever, conjunctivitis, and respiratory distress.

An acute inflammatory disease of the upper RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

The type species of PNEUMOVIRUS and an important cause of lower respiratory disease in infants and young children. It frequently presents with bronchitis and bronchopneumonia and is further characterized by fever, cough, dyspnea, wheezing, and pallor.

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