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Respiratory syncytial virus RSV Vaccines - Biotech, Pharma and Life Science Channel

05:59 EDT 27th August 2016 | BioPortfolio

Respiratory syncytial virus (RSV) infection, which manifests primarily as bronchiolitis and/or viral pneumonia, is the leading cause of lower respiratory tract infection in infants and young children. In the US, RSV LRT infection develops annually in 4-5 million children, and more than 125,000 children are admitted per year for RSV-related illness. RSV disease is the no.1 cause of hospitalization in babies under a year of age in the US. While a monoclonal antibody is commercially available to help prevent RSV disease in infants and children at high risk for severe lung disease from RSV, a RSV vaccine still is not on the market. A number of RSV vaccine candidates have entered clinical development and further are to follow. Also, next generation antibodies against RSV with improved features are in the development pipeline as well as new therapies based on silencing RSV RNA or inhibiting key targets of the virus.

News Articles [864 Associated News Articles listed on BioPortfolio]

Seqirus presents analysis reinforcing the safety and immunogenicity profiles of its MF59®-adjuvanted seasonal trivalent influenza vaccine in adults 65 years and older

MAIDENHEAD, United Kingdom, Aug. 26, 2016 /PRNewswire/ -- Seqirus today announced results from three analyses of a total of 42 clinical trials that evaluated the safety and immunogenicity of...

FDA advises testing for Zika virus in all donated blood and blood components in the US

SILVER SPRING, Md., Aug. 26, 2016 /PRNewswire-USNewswire/ -- As a further safety measure against the emerging Zika virus outbreak, today the U.S. Food and Drug Administration issued a revised guidance...

Increasing R&D investments in Therapeutic Vaccines Market - Merck and GSK Have Interesting Pipelines

HYDERABAD, India, August 26, 2016 /PRNewswire/ -- Mordor Intelligence announces the publication of their research report on the sleep apnea devices market. The report titled, "Global Therapeutic Vacc...

Plastic Bags Cause Infections in Healthcare!

CHICO, Calif., Aug. 26, 2016 /PRNewswire/ -- Infection Prevention Products Inc. releases lab results and test studies that prove the common practice of storing a patient's used respiratory ...

Spotlight Innovation Enters into Sponsored Research Agreement with Florida State University to Support Prof. Hengli Tang in the Development of Treatments for Zika Virus Infection

WEST DES MOINES, Iowa, Aug. 26, 2016 /PRNewswire/ -- Spotlight Innovation Inc. (OTCQB: STLT) has entered into a Sponsored Research Agreement with Florida State University (FSU) to support research dir...

Global Animal Medication Industry

LONDON, Aug. 25, 2016 /PRNewswire/ -- This report analyzes the worldwide markets for Animal Medication in US$ Million by the following End-Use Segments: Companion Animals, and Farm Animals. The Global...

PharmAthene Withdraws Protest Against HHS Over Anthrax Vaccine Bidding Process

ANNAPOLIS, Md., Aug. 25, 2016 /PRNewswire/ -- PharmAthene, Inc. (NYSE MKT: PIP), a biodefense company developing medical countermeasures against anthrax, today announced that after discussions with th...

Pamela Zeitlin, MD, PhD, Named Chair of Pediatrics at National Jewish Health

DENVER, Aug. 25, 2016 /PRNewswire-USNewswire/ -- Nationally renowned Pediatric Pulmonologist Pamela Zeitlin, MD, PhD, has been named Chair of the Silverstein Family Department of Pediatrics at Nationa...

Pregnant Women Can Lower Their Risk Of Birth Defects With A Flu Shot, March Of Dimes Says

  WHITE PLAINS, N.Y., Aug. 25, 2016 /PRNewswire-USNewswire/ -- Getting sick with the flu early in pregnancy makes you twice as likely to have a baby with a serious birth defect of the brain, spin...

Quality Healthcare is a Continuum: PPAHS Interview of Peggy Lange, RT on Intermittent vs. Continuous Monitoring

CHICAGO, Aug. 25, 2016 /PRNewswire/ -- In a recent interview with Peggy Lange, RT (Director of the Respiratory Care Department, St. Cloud Hospital) conducted by the Physician-Patient Alliance for Heal...

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Companies [252 Associated Companies listed on BioPortfolio]

Promise Healthcare Group, LLC

Headquartered in Boca Raton, Florida, Promise Healthcare Group, LLC operates two operating subsidiaries, Promise Healthcare, Inc. and Success Healthcare, LLC, one of the largest l...

MSD Animal Health

For 125 years, MSD has been a global health care leader working to help the world be well. MSD Animal Health, known as Merck Animal Health in the United States and Canada, is the ...

Apria Healthcare Group Inc.

Apria is a privately held company owned by a group of investment limited partnerships managed by affiliates of Blackstone (NYSE:BX). Through its Apria Healthcare LLC operating uni...

PromptCare

PromptCare® is a leading regional provider of specialty respiratory products and infusion therapy services. Established in 1985 and headquartered in Clark, New Jersey, PromptCa...

Zoetis, Inc.

Zoetis (zô-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 60 years of experience in animal heal...

MOLOGEN AG

MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...

IDT Biologika and CMC Biologics

IDT Biologika is an innovative life science company headquartered in Dessau, Germany with extensive expertise in research, development and manufacturing of vaccines, and in additi...

BioTime, Inc. and Asterias Biotherapeutics, Inc.

Asterias Biotherapeutics, Inc. is a leading biotechnology company in the emerging field of regenerative medicine. The company’s proprietary, industry leading platforms are ba...

Inogen, Inc.

Inogen is innovation in oxygen therapy. We are a medical technology company that develops, manufactures and markets innovative oxygen concentrators used to deliver supplemental lo...

electroCore LLC

electroCore LLC, the New Jersey based bioelectric pharma company, is focused on developing non-invasive vagus nerve stimulation therapies (the gammaCore device) for the treatment ...

Clinical Trials [3528 Associated Clinical Trials listed on BioPortfolio]

Segmental Epidural Anesthesia (SEA) V/S General Anesthesia for PCNL

Management of nephrolithiasis has been revolutionized by the advent of shock-wave lithotripsy (ESWL) and percutaneous nephrolithotomy (PCNL). PCNL is a minimally invasive endoscopic techni...

Immuno-Genetic, Inflammation, Retro-Virus, Environnement

Immunology combined to neurobiology now offer prominent tools to yield biomarkers, so far missing in psychiatry, and to design innovative treatment approaches based on the discovery of new...

Interest of Routine Screening for Hepatitis B and C in Patients Receiving Chemotherapy for Solid Tumors

Immunosuppression induced by cancer treatment increases the risk of hepatitis B virus (HBV) and hepatitis C virus (HCV) reactivations. These viral reactivations may be asymptomatic but can...

Measurement of Respiratory Admittance for Pediatric Asthma Diagnosis

The purpose is to characterize the change of respiratory admittance induced by salbutamol inhalation in children and young adults. A variation threshold will be fixed to distinguish asthma...

Trial to Study Intubation Rates of Non-invasive Ventilation Using Pressure Support Ventilation (PSV) Versus Adaptive Support Ventilation (ASV) Mode in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

The clinical course of chronic obstructive pulmonary disease (COPD) is associated with recurrent episodes of exacerbation that results in respiratory failure. The treatment of respiratory ...

A Study to Compare Adaptive Support Ventilation vs. Volume Controlled Ventilation for Management of Respiratory Failure in Patients With Neuroparalytic Snake Envenomation

Neuroparalytic snake envenomation results in severe muscle weakness and respiratory failure. Treatment requires administration of anti-snake venom and supportive care in the form of invasi...

The Effect of Non-invasive Ventilation on the Oxygenation of Peripheral Muscle in Hypercapnic COPD Patients

In this study, 20 hypercapnic COPD patients will perform two constant workrate endurance cycle tests. One test will be while using non-invasive Ventilation (NIV) support, one without in a ...

Respiratory Muscle Function and Neural Respiratory Drive in Interstitial Lung Disease

The purpose of this study is to assess the Respiratory Muscle Function and Neural Respiratory Drive in Interstitial Lung Disease patients.

Sensorimotor Exercises in Virtual Reality Platform in Individuals With Human T-lymphotropic Virus

Testing the effectiveness of an exercise protocol engines sensory performed through a virtual reality platform in individuals infected with HTLV-1

Fucoidan Improves the Metabolic Profiles of Patients With Non-alcoholic Fatty Liver Disease (NAFLD)

Studies reveal special function of fucoidan so far include anti-virus, anti-tumor, immunomodulatory, anti-inflammatory, blood fat, anti-oxidation and liver and kidney dysfunction and impro...

PubMed Articles [6967 Associated PubMed Articles listed on BioPortfolio]

Time Course of MERS-CoV Infection and Immunity in Dromedary Camels.

Knowledge about immunity to Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels is essential for infection control and vaccination. A longitudinal study of 11 dam-calf pairs sh...

Hepatitis E Virus in 3 Types of Laboratory Animals, China, 2012-2015.

We found seroprevalences for hepatitis E virus (HEV) of 7.5%, 18.5%, and 83.3% in specific pathogen-free (SPF) laboratory rabbits, monkeys, and pigs, respectively, in China. HEV RNA was detected in 4....

Aspergillus-positive lower respiratory tract samples in patients with the acute respiratory distress syndrome: a 10-year retrospective study.

The detection of Aspergillus spp. in endotracheal aspirate cultures of mechanically ventilated patients may reflect either colonization or infection. However, little is known about the prevalence and ...

Predicting the optimal geometry of microneedles and their array for dermal vaccination using a computational model.

Microneedle arrays have been developed to deliver a range of biomolecules including vaccines into the skin. These microneedles have been designed with a wide range of geometries and arrangements withi...

Prevalence of Primary HPV in Djibouti: Feasibility of Screening for Early Diagnosis of Squamous Intraepithelial Lesions.

In many African Sub-Saharan countries, human papilloma virus (HPV) prevalence data are not available. The current study estimated the prevalence of HPV virus in the female population of Djibouti.

Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome Coronavirus Infection.

We evaluated the diagnostic and clinical usefulness of blood specimens to detect Middle East respiratory syndrome coronavirus infection in 21 patients from the 2015 outbreak in South Korea. Viral RNA ...

Culex pipiens and Aedes triseriatus Mosquito Susceptibility to Zika Virus.

Genotypes of rubella virus and the epidemiology of rubella infections in the Democratic Republic of the Congo, 2004-2013.

Rubella is a viral infection that may cause fetal death or congenital defects, known as congenital rubella syndrome (CRS), during early pregnancy. The World Health Organization (WHO) recommends that c...

Diagnosing and treating respiratory syncytial virus bronchiolitis.

Respiratory syncytial virus (RSV) is one of the major causes of respiratory tract illness in children and can lead to significant infection and death. This article discusses the incidence, clinical pr...

Biological evaluation of N-2-hydroxypropyl trimethyl ammonium chloride chitosan as a carrier for the delivery of live Newcastle disease vaccine.

Mucosal immune system plays a very important role in antiviral immune response. We prepared Newcastle disease viruses (NDV) encapsulated in N-2-hydroxypropyl trimethyl ammonium chloride chitosan (N-2-...

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Medical and Biotech [MESH] Definitions

Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES.

Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.

A species of PNEUMOVIRUS causing an important respiratory infection in cattle. Symptoms include fever, conjunctivitis, and respiratory distress.

An acute inflammatory disease of the upper RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

The type species of PNEUMOVIRUS and an important cause of lower respiratory disease in infants and young children. It frequently presents with bronchitis and bronchopneumonia and is further characterized by fever, cough, dyspnea, wheezing, and pallor.

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