Shock - Biotech, Pharma and Life Science Channel
PubMed Articles
TsDAF-21/Hsp90 is expressed in all examined stages of Trichinella spiralis.
Trichinella is an important parasitic nematode of animals worldwide. Heat shock proteins are ubiquitous in nature and allow organisms to quickly respond to environmental stress. A portion of the Tsdaf...
Aims: Recent studies have demonstrated favourable clinical outcomes for the everolimus-eluting bioresorbable vascular scaffold (BVS) ABSORB™ in patients with stable coronary artery disease. There is...
Early-life stress is a main contributory factor to the onset of depression. Treatments remain inadequate and as such, a large unmet medical need for novel therapeutics remains. Impeding advancement is...
Film review: Two amide-containing bisolefin monomers undergo solid-state polymerization (see example) through a [2+2] reaction in a single-crystal-to-single-crystal fashion. The transformation was fav...
We isolated and functionally characterized the alpha- and beta- subunits (ApCpnA and ApCpnB) of a chaperonin from Aeropyrum pernix K1. The constructed vectors pET3d- ApCpnA and pET21a-ApCpnB were tran...
Mycorrhizal inoculation of conifer roots is a key strategy to optimize establishment and performance of forest tree species under both natural and cultivated conditions and also to mitigate transplant...
Levosimendan for the treatment of subarachnoid hemorrhage-related cardiogenic shock.
PURPOSE: Pulmonary vascular dysfunction is common during acute respiratory distress syndrome (ARDS), but there is controversy concerning prevalence and prognosis of cor pulmonale during protective ven...
The role of heat shock proteins in bladder cancer.
Heat shock proteins (HSPs) and clusterin (another chaperone protein with HSP-like properties) are present in normal cells and are upregulated by cellular stressors such as hyperthermia, hypoxia, and c...
Honey bee promoter sequences for targeted gene expression.
The honey bee, Apis mellifera, displays a rich behavioural repertoire, social organization and caste differentiation, and has an interesting mode of sex determination, but we still know little about i...
News Articles
Hospital Mortality In Septic Shock Patients In The ICU Affected By Source Of Infection
In ICU patients who have septic shock, the anatomic source of infection has a strong effect on the chances of survival, according to a new study from researchers in Canada. "Understanding the local in...
How To Get A Girlfriend: Dating Expert Reveals Five Key Steps in Vital New Release
New report by Carlos Xuma offers men tips on how to put their best foot forward with the women who catch their eyes and more. San Mateo, CA (PRWEB) May 21, 2013 To many men, getting a girlfriend seem...
Democrats Push Back Against Claims Of Health Law 'Rate Shock'
House Energy and Commerce Committee Democrats countered GOP claims that the health law is driving up insurance premiums by analyzing initial rate filings in five states. The Hill: Dems: Early Data Sh...
Nobel laureate plays down flu pandemic scaremongering
A Nobel prize-winning scientist Tuesday played down "shock-horror scenarios" that a new virus strain will emerge with the potential to kill millions of people.
New Role For ECMO In Treating Patients With Cardiac Arrest And Profound Shock
Extracorporeal membrane oxygenation (ECMO), a procedure traditionally used during cardiac surgeries and in the ICU that functions as an artificial replacement for a patient's heart and lungs, has also...
Shock -- Administered Uninterrupted Chest Compressions
With the advent of gel adhesive pads, is it still dangerous for medical professionals to administer continuous chest compressions during defibrillation? American Academy of Emergency Medicine
Structural basis for alternating access of a eukaryotic calcium/proton exchanger
Eukaryotic Ca2+ regulation involves sequestration into intracellular organelles, and expeditious Ca2+ release into the cytosol is a hallmark of key signalling transduction pathways. Bulk removal of Ca...
Sensors For Heart Devices, Consumer Electronics, Vulnerable To Certain Security Risks
The type of sensors that pick up the rhythm of a beating heart in implanted cardiac defibrillators and pacemakers are vulnerable to tampering, according to a new study conducted in controlled laborato...
Source of infection affects hospital mortality in septic shock patients in the ICU
(American Thoracic Society) In ICU patients who have septic shock, the anatomic source of infection has a strong effect on the chances of survival, according to a new study from researchers in Canada.
Degenerative Changes Identified in Spinal Discs and Reversed With Drug Cocktail In Diabetic Mice
New York, NY (PRWEB) May 17, 2013 Degenerative changes to the area of the spinal disc that absorbs most of the shock felt with compression, known as the nucleus pulposus, has been demonstrated and...
Events
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Companies
X2IMPACT is a Seattle-based technology company developing impact monitoring systems designed to provide real time, high quality information about head impact events that cause spo...
SKYDEX, a privately held technology company with headquarters in Denver, is the industry leader in developing protective materials that mitigate shock, vibration and energy forces...
Vasomedical, Inc. is primarily engaged in designing, manufacturing, marketing and supporting EECP® external counterpulsation systems based on the Company's proprietary technolo...
A privately held corporation founded in 1995 specifically for the promotion, manufacture, and sale of customized Brain-Pad® dual-arch mouth-guards designed to reduce the risk o...
Medical Protection Technologies
Medical Protection Technologies, based in Friday Harbor, Wash., is the exclusive North American provider of medical device products made from the unique shock-absorbing material D...
Shock Doctor is the market and technology leader in mouthguards. The company transformed and elevated the mouthguard industry by introducing innovative, shock absorbing, superior fitting self-custom m...
Clinical Trials
Lactic Acid in the Rectum and Life-Threatening Infection
Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of lactic acid. The investigators hypothesize, that the...
Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome
Nitric oxide (NO) plays a pivotal role in maintenance of normal vascular tone. However, in sepsis the excessive production of NO results in myocardial depression, vasoplegia, and cytotoxic...
Change and Clinical Significance of Plantar Fascia Thickness After ESWT
The aim of the study is to investigate the effect of extracorporeal shock wave therapy (ESWT) on the thickness of plantar fascia measured by ultrasonographic examination among patients wit...
Psychological Support for Patients With an Implantable Cardioverter Defibrillator
About 30% of patients survive a cardiac arrest, and the majority of these receive an implantable cardioverter defibrillator (ICD) for prevention of sudden cardiac death (SCD). While ICD th...
AED Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute"
The aim of the trial is to evaluate a new AED algorithm that proposes a new timeline between the time devoted to administer a defibrillation shock, and the time devoted to chest compressio...
Dopexamine and Norepinephrine Compared With Epinephrine Alone in Septic Shock
In septic shock, when volume resuscitation fails to restore mean arterial pressure, catecholamines such as dopamine, dobutamine, epinephrine, or norepinephrine are used, either alone or in...
The purpose of this study is to learn how blood clotting substances respond in children with septic shock, low platelet counts, and multiple organ failure (MOF) treated at different instit...
A Safety and Effectiveness Study of Vaccine Therapy in Patients With Indolent Lymphoma
Primary Objectives: - To document the efficacy of treatment with autologous lymphoma-derived HSPPC-96 of selected patients with indolent lymphoma. The efficacy endpoints are:...
Timing of Voluntary Movement in Patients With Schizophrenia
This study will examine and compare how the brain controls the timing of movement in healthy volunteers and in people with schizophrenia. Previous experiments have shown that when people a...
This study will examine the role of the spinal cord in improving leg movements after physical training in healthy people. The results of this study may be helpful in developing new rehabil...
Videos
Medical and Biotech [MESH] Definitions
Gtp-binding Protein Alpha Subunits, G12-g13
A ubiquitously expressed family of heterotrimeric GTP-binding protein alpha subunits that signal through interactions with a variety of second messengers as GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; and HEAT SHOCK PROTEINS. The G12-G13 part of the name is also spelled G12/G13.
Hsc70 Heat-shock Proteins
A constitutively expressed subfamily of the HSP70 heat-shock proteins. They preferentially bind and release hydrophobic peptides by an ATP-dependent process and are involved in post-translational PROTEIN TRANSLOCATION.
Hsp72 Heat-shock Proteins
Stress-inducible members of the heat-shock proteins 70 family. HSP72 heat shock proteins function with other MOLECULAR CHAPERONES to mediate PROTEIN FOLDING and to stabilize pre-existent proteins against aggregation.
Hsp20 Heat-shock Proteins
A subfamily of small heat-shock proteins that are closely related to ALPHA B-CRYSTALLIN. Hsp20 heat-shock proteins can undergo PHOSPHORYLATION by CYCLIC GMP-DEPENDENT PROTEIN KINASES.
Heat-shock Proteins, Small
A family of low molecular weight heat-shock proteins that can serve as MOLECULAR CHAPERONES.
