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Sleep Disorders - Biotech, Pharma and Life Science Channel

06:05 EDT 23rd May 2013 | BioPortfolio

Sleep disorders disrupt sleep during the night, or cause sleepiness during the day, caused by physiological or psychological factors.

The common ones include snoring and sleep apnea, insomnia, parasomnias, sleep paralysis, restless legs syndrome, circadian rhythm disorders, narcolepsy, chronic fatigue syndrome, jet lag and seasonal affective disorder.

Sleep is important in allowing out bodies to recover, and grow. Disturbances in sleep can cause great unhappiness, and can have a profound affect on day-to-day activities.

Source; Adapted from About.com

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PubMed Articles [ 6598 Associated PubMed Articles listed on BioPortfolio]

Sleep-Disordered Breathing and Postoperative Outcomes After Bariatric Surgery: Analysis of the Nationwide Inpatient Sample.

BACKGROUND: Sleep-disordered breathing (SDB), also known as obstructive sleep apnea (OSA), has been increasingly recognized as a possible risk factor for adverse perioperative outcomes in non-bariatri...

Home sleep study characteristics in patients with mucopolysaccharidosis.

BACKGROUND: Mucopolysaccharidoses (MPS) are a group of inherited lysosomal storage disorders caused by the deficiency of hydrolases involved in the degradative pathway of glycosaminoglycans. In MPS, u...

Distribution of interstitial cells of Cajal in Meriones unguiculatus and alterations in the development of incomplete intestinal obstruction.

The interstitial cells of Cajal (ICCs) act as pacemaker cells that are involved in gastrointestinal (GI) motility disorders, although the pathogenesis of these disorders is still unclear. The GI tract...

Magnetic resonance imaging for simultaneous morphological and functional evaluation of esophageal motility disorders.

PURPOSES: The purpose of this study was to evaluate the feasibility and safety of esophageal functional magnetic resonance imaging (fMRI) for the diagnosis of achalasia. METHODS: Eleven patients with...

Leptin's Activity on the Hydroxyl Radical: A Possible Link to the Oxidative Stress-Related Endothelial Vasodilation in Patients with Obstructive Sleep Apnea.

PURPOSE: Obstructive sleep apnea (OSA) is associated with increased cardiovascular morbidity, whereas the underlying mechanism is still eluding, the thought participants are chronic intermittent hypox...

Revisiting Down syndrome from the ENT perspective: review of literature and recommendations.

Down syndrome is the most common chromosomal abnormality among live born infants reaching up to 1 in 700 births and is characterized by a variety of dysmorphic features and medical conditions. The pot...

High rate of disease-related copy number variations in childhood onset schizophrenia.

Copy number variants (CNVs) are risk factors in neurodevelopmental disorders, including autism, epilepsy, intellectual disability (ID) and schizophrenia. Childhood onset schizophrenia (COS), defined a...

An MRI atlas of the mouse basal ganglia.

The basal ganglia are a group of subpallial nuclei that play an important role in motor, emotional, and cognitive functions. Morphological changes and disrupted afferent/efferent connections in the b...

Sirtuin deacetylases in neurodegenerative diseases of aging.

Sirtuin enzymes are a family of highly conserved protein deacetylases that depend on nicotinamide adenine dinucleotide (NAD+) for their activity. There are seven sirtuins in mammals and these proteins...

Movement disorders: Novel MRI measure for diagnosis of progressive supranuclear palsy.

News Articles [ 5697 Associated News Articles listed on BioPortfolio]

University Services Announces Expansion of its pm-Assist® Sleep Scoring & Interpretation Service

University Services’ pm-Assist® service now offers additional opportunities to medical professionals and insurance companies including diagnostic pathway determination, shipping of home sleep t...

FDA panel backs Merck & Co sleep drug but at low doses

FDA panel backs Merck & Co sleep drug but at low doses

EEG Diagnostic Specialist MentisCura Joins Stockholm Brain Institute Consortium

MentisCura Diagnostics will contribute as a partner and board member of the Stockholm Brain Institute, a consortium for cognitive and computational neuroscience, led by the Karoli...

Study explains gender differences in the impact of OSA on cardiovascular disease, mortality

A new study from researchers in Japan indicates that obstructive sleep apnea is independently associated with visceral (abdominal) fat accumulation only in men, perhaps explaining gender differences i...

Study: Sleep disturbance may contribute to depression risk by impairing emotion regulation

A new study provides neurobiological evidence for dysfunction in the neural circuitry underlying emotion regulation in people with insomnia, which may have implications for the risk relationship betwe...

Disturbed sleep in adolescents associated with depressed mood, uncertainly about future success

A new study suggests that disturbed sleep in adolescents is associated with more symptoms of depression and greater uncertainly about future success. However, perceived support and acceptance from par...

Sleep Quality And School Performance Impaired By Asthma Symptoms

The negative effects of poorly controlled asthma symptoms on sleep quality and academic performance in urban schoolchildren has been confirmed in a new study...

Addressing Mental Health Issues In HIV Care

The integration of mental health interventions into HIV prevention and treatment platforms can reduce the opportunity costs of care and improve treatment outcomes, argues a new Policy Forum article pu...

Sleep Apnea Symptoms In Childhood Treated By Early Removal Of Adenoids And Tonsils

Adenotonsillectomy, or the removal of the adenoids and tonsils, is performed 500,000 times a year in the United States, often as a treatment for children with obstructive sleep apnea. However, the pro...

FDA panel says Merck's sleep drug safe, effective at lower dose

WASHINGTON (Reuters) - Merck & Co's experimental insomnia drug was safe and effective at the lower of two doses studied, a panel of medical experts said on Wednesday, increasing the chance it will be...

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Companies [ 232 Associated Companies listed on BioPortfolio]

Acorda Therapeutics

Acorda Therapeutics, Inc. was established in March 1995 to develop therapeutic products for spinal cord injury ("SCI") and other central nervous system disorders. Acorda is focusing its initial develo...

ALung Technologies, Inc.

ALung Technologies, Inc. is commercializing artificial lung devices for the treatment of acute and chronic respiratory disorders. The company's Hemolung System, designed to replace or supplement the u...

Targeted Medical Pharma, Inc.

Physician Therapeutics is a division of Targeted Medical Pharma, Inc., a specialty pharmaceutical company that develops and sells prescription medical foods to physi...

Reverse Medical Corporation

Reverse Medical Corporation is a privately-held medical device company focused on expanding the endovascular management of acute stroke and neurovascular disease. The technology p...

U.S. Physical Therapy, Inc.

Founded in 1990, U.S. Physical Therapy, Inc. (NASDAQ:USPH) operates 369 clinics in 43 states. The Company's clinics provide preventative and post-operative care for a variety of o...

Onconova Therapeutics, Inc.

Onconova, based in Newtown, PA and Lawrenceville, NJ, discovers and develops novel patent- protected small molecule therapeutic agents for cancer, radiation protection and hematol...

Heart Rhythm Society

The Heart Rhythm Society is the international leader in science, education and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorder...

TheAmerican Association of Clinical Endocrinologists (AACE)

The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...

Lineagen, Inc.

Lineagen (www.lineagen.com) is a provider of diagnostic and healthcare services focused on complex diseases for which individuals’ genetic profiles contribute strongly to...

Good Start Genetics, Inc.

Good Start Genetics provides the most clinically relevant genetic information to physicians. The Company’s affordable pre-pregnancy test, which was developed by the Co...

Clinical Trials [ 1963 Associated Clinical Trials listed on BioPortfolio]

Omega-3 Fatty Acids in Autism Spectrum Disorders

This is a 12-week open label trial to evaluate whether omega-3 fatty acids is effective in reducing the severity of autism and its comorbidities.

Continuous Positive Airway Pressure (CPAP) for Fatigue in Patients With Multiple Sclerosis (MS) and Obstructive Sleep Apnea (OSA)

Fatigue is a symptom present in 76 to 92% of people with multiple sclerosis (MS). Fatigue is usually described as an overwhelming sense of tiredness, lack of energy, and feeling of exhaust...

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of,...

Impact of Hot Flashes on Sleep and Mood Disturbance

We plan to enroll 60 healthy, non-pregnant premenopausal women age 18-45 who do not have hot flashes (in order to have 30 women complete all study procedures) in a trial investigating the...

Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)

This is a Phase III, multicenter, open-label study of RI-002 administered as an intravenous infusion of RI-002 (IGIV) every 21 or 28 days in approximately 60 subjects with Primary Immunode...

An Interventional Study to Assess the Efficacy and Safety of Buprenorphine in Korean Patients With Spinal Disorders

The purpose of this study is to assess the pain reduction rate after 8 weeks treatment of NORSPAN® from baseline. And secondary purpose are: pain reduction rate after 4 weeks treatment f...

Paroxetine-CR to Treat Post-Traumatic Stress Disorder (PTSD) Symptomatic After Initial Exposure Therapy

Both pharmacotherapeutic and psychosocial interventions have domenstrated efficacy for PTSD. However, although these interventions can be helpful, many patients remain symptomatic despite...

Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-Year Manometric Follow-Up

Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. In...

Proton Pump Inhibitor Therapy for Mild to Moderate Obstructive Sleep Apnea

Obstructive Sleep Apnea (OSA) is common in modern society, affecting up to 5% of working middle-aged adults in the United States. Obesity is the number one risk factor for the development...

Bipolar Disorder Research Study for Ages 12 and Older

The Bipolar Disorder Center for Pennsylvanians aims to reduce significant differences in treatment results among Pennsylvanians with bipolar disorder, especially among youth, the elderly,...

Medical and Biotech [MESH] Definitions

Tribulus

A plant genus of the family ZYGOPHYLLACEAE. Members contain steroidal saponins. Ingestion by grazing animals causes PHOTOSENSITIVITY DISORDERS called geeldikkop (yellow thick head) in South Africa.

Genetic Services

Organized services to provide diagnosis, treatment, and prevention of genetic disorders.

Gordonia Bacterium

A genus of gram-positive BACTERIA in the family Gordoniaceae, isolated from soil and from sputa of patients with chest disorders. It is also used for biotransformation of natural products.

Mastocytosis, Systemic

A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.

Genetic Research

Research into the cause, transmission, amelioration, elimination, or enhancement of inherited disorders and traits.

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