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Somatropin Hgh rDNA Pfizer - Biotech, Pharma and Life Science Channel

11:25 EDT 19th June 2013 | BioPortfolio

What is GENOTROPIN?

GENOTROPIN (somatropin [rDNA origin] for injection) is a growth hormone treatment. It is an exact copy of the natural growth hormone that our bodies make. The main difference is that GENOTROPIN is man-made.

With its established safety profile. GENOTROPIN is approved by the Food and Drug Administration (FDA) to treat growth failure in:

* Children with idiopathic short stature (ISS)
* Children born small for gestational age (SGA)
* Girls with Turner syndrome (TS)
* Children with growth hormone deficiency (GHD)
* Children with Prader-Willi syndrome (PWS)

GENOTROPIN is also approved by the FDA to treat:

* Adults with growth hormone deficiency (GHD)

Souorce: Genotropin

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Medical and Biotech [MESH] Definitions

Actinobacteria

Class of BACTERIA with diverse morphological properties. Strains of Actinobacteria show greater than 80% 16S rDNA/rRNA sequence similarity among each other and also the presence of certain signature nucleotides. (Stackebrandt E. et al, Int. J. Syst. Bacteriol. (1997) 47:479-491)

Mason-pfizer Monkey Virus

A species of BETARETROVIRUS isolated from mammary carcinoma in rhesus monkeys. It appears to have evolved from a recombination between a murine B oncovirus and a primate C oncovirus related to the baboon endogenous virus. Several serologically distinct strains exist. MPMV induces SIMIAN AIDS.

Simian Acquired Immunodeficiency Syndrome

Acquired defect of cellular immunity that occurs naturally in macaques infected with SRV serotypes, experimentally in monkeys inoculated with SRV or MASON-PFIZER MONKEY VIRUS; (MPMV), or in monkeys infected with SIMIAN IMMUNODEFICIENCY VIRUS.

Human Growth Hormone

A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.

Dna, Ribosomal Spacer

The intergenic DNA segments that are between the ribosomal RNA genes (internal transcribed spacers) and between the tandemly repeated units of rDNA (external transcribed spacers and nontranscribed spacers).

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