Spectrum of activity - Biotech, Pharma and Life Science Channel
PubMed Articles
Lactation is the most energy-demanding phase of mammalian reproduction, and lactation performance may be affected by events during pregnancy. For example, food intake may be limited in late pregnancy...
A series of new strobilurin-pyrimidine analogs were designed and synthesized based on the structures of our previously discovered antiproliferative compounds I and II. Biological evaluation with two h...
Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor.
Probestin is a potent aminopeptidase N (APN) inhibitor originally isolated from the bacterial culture broth. Here, we report probestin synthesis by solid phase peptide synthesis (SPPS) method and eval...
Novel pyrazole-benzimidazole derivatives have been designed and synthesized. The entire target compounds were determined against cancer cell lines U937, K562, A549, LoVo and HT29 and were screened for...
This study determined the prevalence of classical onconeural Ab in a series of 2063 consecutive patients that were investigated because of suspicion of PNS as well as evaluated individual onconeural A...
In vivo imaging of brain metabolism activity using a phosphorescent oxygen-sensitive probe.
Several approaches have been adopted for real-time imaging of neural activity in vivo. We tested a new cell-penetrating phosphorescent oxygen-sensitive probe, NanO2-IR, to monitor temporal and spatial...
We have firstly established a method of high-performance liquid chromatography-ultraviolet analysis coupled with electrospray ionization-ion trap-time-of-flight mass spectrometry and butyrylcholineste...
Molecular mechanisms of the antitumor activity of SB225002: A novel microtubule inhibitor.
SB225002 (SB) is an IL-8 receptor B (IL-8RB) antagonist that has previously been shown to inhibit IL-8-based cancer cell invasion, and to possess in vivo anti-inflammatory and anti-nociceptive effects...
Mendel: the Swiss army knife of genetic analysis programs.
Mendel is one of the few statistical genetics packages that provide a full spectrum of gene mapping methods, ranging from parametric linkage in large pedigrees to genome-wide association with rare var...
Increasing environmental pollution by carcinogens such as some of persistent organic pollutants (POPs) has prompted growing interest in searching for chemopreventive compounds which are readily obtain...
News Articles
Increasing physical activity requires increasing energy intake in elderly
Response to ‘Increasing physical activity requires increasing energy intake in elderly’
Helping Prevent Obesity Among Children Via Community-Based Programs
When it comes to confronting childhood obesity, researchers at the Johns Hopkins Bloomberg School of Public Health conclude that community-based approaches are important. A systematic review of childh...
Functions of cofilin in cell locomotion and invasion
Cofilin severing activity can generate free actin filament ends that are accessible for F-actin polymerization and depolymerization. The combination of structural data for filament severing with recen...
Ranbaxy Hit By EU Pay-For-Delay Fine Of $13.7 Million
Troubled Ranbaxy Laboratories has been hit by another charge, this one a $13.7 million fine imposed by the EU for antitrust violations involving pay-for-delay activity.
Researchers identify emotions based on brain activity
For the first time, scientists at Carnegie Mellon University have identified which emotion a person is experiencing based on brain activity.
Exercise And Eating Habits Of Mothers Can Affect Their Children
redOrbit Staff & Wire Reports - Your Universe Online Mothers who practice what they preach when it comes to being active and making healthy food choices are more likely to have children who exerc...
MMR booster does not result in worse JIA disease activity in children
Among children with juvenile idiopathic arthritis who had undergone primary immunization, the use of a measles-mumps-rubella booster compared with no booster did not result in worse JIA disease activi...
US Adults Are Lax on Meeting National Exercise Guidelines
Too many US adults are missing out on the health benefits of exercise, as only 20% meet federal recommendations for both aerobic and muscle-strengthening activity.
Summer is a fun time for kids and families, and everyone spends more time outdoors in warm weather. While it is important to encourage healthy physical activity such as bike riding and other exercise,...
Events
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Companies
BIOTECanada is the national association representing the broad spectrum of biotech constituents including emerging and established companies in the health, agricultural, and industrial sectors, as wel...
Reverse Medical Corporation is a privately-held medical device company focused on expanding the endovascular management of acute stroke and neurovascular disease. The technology p...
Aegerion Pharmaceuticals, Inc.
Aegerion Pharmaceuticals is a biopharmaceutical company dedicated to the development and commercialization of innovative, life-altering therapies for patients with debilitating often fatal, rare dis...
Edge Therapeutics, Inc. is a private, clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products that improve patient outcome...
Pepper Hamilton LLP is a multi-practice law firm with 400 lawyers in 10 offices. The firm provides corporate, litigation and regulatory legal services to leading businesses, governmental entities, non...
Serving the nonprofit and education sectors for 30 years, Blackbaud (NASDAQ: BLKB) combines technology and expertise to help organizations achieve their missions. Blackbaud works...
Based in Phoenix, Ariz., Eldorado, a division of MphasiS, an HP Company, specializes in health insurance application development, business process outsourcing services, informatio...
Anthem Blue Cross and Blue Shield Foundation
Through charitable grant making, the Anthem Blue Cross and Blue Shield Foundation LLC, an independent licensee of the Blue Cross and Blue Shield Association, promotes Anthemâ...
Based in Brisbane, California, XDx is a molecular diagnostics company focused on the discovery, development and commercialization of noninvasive gene expression-based tests for th...
Enamine is a diversified provider of discovery chemistry for pharmaceutical and agrochemical industry needs. The main line of the company activity is organic compound synthesis for screening. Besides...
Clinical Trials
A Safety Study in Patients With Chronic Lymphocytic Leukemia
This is an open-label, dose-escalation study to determine the tolerability, safety profile, and antitumor activity of SGN-40 in patients with CLL. All patients will receive dose escalation...
Efficacy of Pazopanib in Gastrointestinal Stromal Tumors (GIST)
The purpose of this study is to evaluate the antitumor activity of pazopanib in patients with metastatic and/or locally advanced unresectable Gastrointestinal Stromal Tumors (GIST) resista...
Milnacipran in Autism and the Functional Locus Coeruleus and Noradrenergic Model of Autism
Autism Spectrum Disorders (ASD) include Autistic disorder, Asperger's syndrome and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS). These are developmental disorders be...
Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.
Relative Bioavailability of Oral Suspension of Rivaroxaban Compared to Standard Tablet
Rivaroxaban is a substance developed for use in the treatment of blood coagulation disorders. Thrombosis (blood clots) can occur as a result of excessive coagulation activity in the blood...
Physical Activity and Cognitive Behavioural Therapy in Panic Disorder
Physical activity (treadmill) supports the effect of cognitive behavioural therapy in patients with panic disorder with/without agoraphobia
Cell Lines From High-Risk Breast Tissue
Background: - Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation...
Omega-3 Fatty Acids in Autism Spectrum Disorders
This is a 12-week open label trial to evaluate whether omega-3 fatty acids is effective in reducing the severity of autism and its comorbidities.
1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain
We will conduct a 12-week, randomized open label study, comparing usual care (UC) antipsychotic treatment (aripiprazole, quetiapine, risperidone) with ziprasidone (ZIP) in children and ado...
Low-level Laser Therapy on Temporomandibular Disorder
The purpose of this study is to assess the effect of low-level laser on pain, occlusal contacts, mandibular movements and electromyography activity in the masseter and temporal muscles in...
Videos
Electromagnetic Spectrum An Activity
Check out us at:http://physics.tutorvista.com/waves/electromagnetic-spectrum.html Define Electromagnetic Spectrum The electromagnetic radiation of all the po...
Medical and Biotech [MESH] Definitions
Lippia
A plant genus of the family VERBENACEAE. Lippsidoquinone; TRITERPENES; SESQUITERPENES; and THYMOL have been found in this genus. Plant extracts have cytotoxic activity. It is sometimes called Mexican oregano but that confuses it with real oregano (ORIGANUM).
Judicial Role
The kind of action or activity proper to the judiciary, particularly its responsibility for decision making.
Millettia
A plant genus of the family FABACEAE. Members contain ISOFLAVONES, some of which show molluscicidal and schistosomicidal activity. Some species of Pongamia have been reclassified to this genus and some to DERRIS.
Thrombopoiesis
The process of generating thrombocytes (BLOOD PLATELETS) from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via the MEGAKARYOCYTES. The humoral factor with thrombopoiesis-stimulating activity is designated THROMBOPOIETIN.
Montanoa
A plant genus of the family ASTERACEAE. Steroidal activity has been observed in animals. Members of this genus contain sesquiterpene lactones such as tomentosin, OXEPINS such as zoapatanol, and kaurene type DITERPENES.
