Streptokinase Astra - Biotech, Pharma and Life Science Channel
PubMed Articles
BACKGROUND: A delayed approach is recommended for reconstruction of the jaws with autogenous bone grafts and dental implants. Experimental studies have shown stronger bone tissue responses to surface...
Objective: To evaluate bone loss around implants placed in patients with a history of treated chronic periodontitis and who did or did not attend supportive periodontal therapy, after one year in func...
Aims: Surgery after drug-eluting stent (DES) implantation may be associated with increased risk for perioperative stent thrombosis (ST). Methods and results: We evaluated the outcomes of 67 patients w...
PURPOSE: The aim of the present study was to evaluate deviations between virtually planned and placed implants by the use of skeletally supported stereolithographic templates. MATERIALS AND METHODS: T...
AIM: The aim of this study was to evaluate soft and hard tissue alterations around implants placed in healed, sloped ridge sites. MATERIALS AND METHODS: In this prospective multi-center study, 65 pati...
Three studies were conducted to determine the potential of experimental feed additives (EFAs), clays or non-digestible yeast oligosaccharides, to reduce milk aflatoxin (AFM(1) ) concentrations in lact...
Little is known about the impact of thrombolytic agents on in-hospital outcomes in the Middle East. The objective of this study was to evaluate the impact of thrombolytic agents on in-hospital outcome...
Summary Titanium or zirconium computer-aided design/computer-aided manufacturing abutments are now widely used for aesthetic implant treatments; however, information regarding microscopic structura...
This study was undertaken to isolate a flavonol, kaempferol, from the fruits of Lagenaria siceraria (bottle gourd) as a sole compound and to explore the fibrinolytic potential of the methanolic extrac...
Enhanced implant integration with hierarchically structured implants: a pilot study in rabbits.
Aim: To investigate bone-to-implant bonding for some novel surface modifications with a hierarchic structure and to correlate the in vivo results with surface roughness parameters. Materials and metho...
News Articles
In final draft guidance published in recent weeks, NICE has recommended dapagliflozin (Forxiga, Bristol-Myers Squibb and Astra Zeneca) for some people with type 2 diabetes. The agency changed its posi...
In final draft guidance published in recent weeks, NICE has recommended dapagliflozin (Forxiga, Bristol-Myers Squibb and Astra Zeneca) for some people with type 2 diabetes. ��The agency ch...
Fortune 500 Healthcare Products Company Selects NextDocs to Manage Document Compliance
CONSHOHOCKEN, Pa., June 13, 2013 /PRNewswire/ -- NextDocs announced today that it has signed its largest and most comprehensive contract to date for its regulated content management and complianc...
Enttäuschende Resultate in Studien haben den Arzneimittelhersteller dazu veranlasst, die Entwicklung des Medikaments abzubrechen. Dabei ist das Repertoire an neuen Präparaten ohnehin schon unterbes....
Array's selumetinib meets in Phase II ocular melanoma
Researchers at Memorial Sloan-Kettering Cancer Center presented data at the American Society of Clinical Oncology meeting showing that oral selumetinib from Array BioPharma Inc. (NASDAQ:ARRY) met the...
NextDocs Expands Customer Roster by More Than 10 Percent
CONSHOHOCKEN, Pa. and TOKYO, June 3, 2013 /PRNewswire/ -- NextDocs, the global leader in compliance solutions for regulated industries, announced today that it has expanded its client roster by m...
AstraZeneca is a top pharmaceutical company based in London, United Kingdom. The company source its origins back to 1913, however the most recent incarnation is the result of numerous M&A deals ov...
AstraZeneca: M&A activity 2005-2013
AstraZeneca has also announced 7 M&A deals since 2005, with the lead deals being the acquisition of MedImmune, Ardea Biosciences and Astra Tech. Abstracted from: Partnering Deals and Alliances wit...
NICE recommends AZ, BMS diabetes drug
The National Institute of Health and Clinical Excellence (NICE) is recommending that doctors can prescribe a new diabetes drug made by AstraZeneca and Bristol-Myers Squibb on the NHS, after rejecting...
UK cost agency backs Astra, Bristol diabetes drug in some cases
LONDON, May 30 (Reuters) - Britain's healthcare cost watchdog NICE is recommending a new diabetes drug from Bristol-Myers Squibb and AstraZeneca in some circumstances, marking a change of tack followi...
Events
None
Companies
DENTSPLY Implants is the union of two successful and innovative dental implant businesses: DENTSPLY Friadent and Astra Tech Dental. DENTSPLY Implants offers a comprehensive line o...
Astra Tech AB, a company in the Astra Zeneca group, is a global leader in dental, surgical and urological products, services and support. An innovation-driven company since the st...
GTS Medical Translation Services
GTS provides certified medical translation services to leading pharmaceutical companies, medical device companies and CROs. Customers include Astra Zeneca, GSK, Teva Pharmaceuticals, Siemens, Boston...
The contents of this Web site are copyrighted. Astra Tech and its subsidiaries, members of the AstraZeneca group of companies (collectively, the "Company"), hereby authorize you to copy documents publ...
Clinical Trials
This is a study to evaluate immediate implants.
Intravenous Streptokinase in Acute Myocardial Infarction
To determine whether the administration of intravenous streptokinase (SK) early in the course of acute, transmural myocardial infarction would limit myocardial damage.
Thrombolysis in Myocardial Infarction (TIMI)
In TIMI I, to assess the relative thrombolytic activity and side effects of intravenous recombinant tissue-type plasminogen activator (rt-PA) versus intravenous streptokinase in patients w...
Randomized Clinical Trial of Non-Surgical Reperfusion of the Coronary Arteries
To assess the effect of non-surgical reperfusion on infarct size in patients with acute myocardial infarction.
Desflurane Versus Propofol Anesthesia for Off-Pump CABG
The purpose of this study is to prove if anesthesia maintained with the inhaled volatile anesthetic desflurane is superior to the intravenously applied propofol anesthesia in off-pump coro...
The investigators hypothesized that complementary intracoronary streptokinase administration to primary percutaneous intervention in patients with acute myocardial infarction may provide...
The optimal dosage and duration of administration of clot-dissolving medications for the treatment of patients with mechanical heart valves with clots is not known. We hypothesized that a...
Case Series Evaluation of a Short Dental Implant
Following the loss of teeth, the alveolar bone formed in response to the eruption of the teeth is gradually resorbed by the body. In conventional dental implant therapy, a wide safety marg...
The purpose of this study is primarily to evaluate implant survival rate of Astra Tech Fixture ST placed in the posterior maxilla. A one-stage surgical protocol will be used and the implan...
The purpose of the study is to evaluate Astra Tech Dental Implant System, Fixture Osseospeed™, in patients with tooth loss in the posterior mandible in an early loading protocol. Primary...
Videos
Medical and Biotech [MESH] Definitions
Streptodornase And Streptokinase
A mixture of the enzymes (streptokinase and streptodornase) produced by hemolytic streptococci. It is used topically on surface lesions and by instillation in closed body cavities to remove clotted blood or fibrinous or purulent accumulations. It is also used as a skin test antigen in evaluating generalized cell-mediated immunodeficiency. (Dorland, 27th ed) EC 3.-.
Streptokinase
Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.
Anistreplase
An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acyl group is slowly hydrolyzed, producing an activator that converts plasminogen to plasmin, thereby initiating fibrinolysis. Its half-life is about 90 minutes compared to 5 minutes for TPA; (TISSUE PLASMINOGEN ACTIVATOR); 16 minutes for UROKINASE-TYPE PLASMINOGEN ACTIVATOR and 23 minutes for STREPTOKINASE. If treatment is initiated within 3 hours of onset of symptoms for acute myocardial infarction, the drug preserves myocardial tissue and left ventricular function and increases coronary artery patency. Bleeding complications are similar to other thrombolytic agents.
