Stroke CVA - Biotech, Pharma and Life Science Channel
A stroke is a cerebrovascular accident that results in inadequate blood flow to part of the brain, starving it of oxygen and causing immediate and irreversible changes to the neurones. If affects 150,000 people a year in the UK; one every 5 minutes.
Symptoms include becoming numb, weak or paralysed on one side of the body, with possible slurred speech, blurred vision and unsteadiness. It is a medical emergency. Depending on the area of the brain affected, the resulting irreversible changes can detrimentally affect bodily functions, thought processes, and ability to learn and communicate. Recovering from a stroke takes time, and some functions may slowly be regained, but often not the their original level.
There are 2 types of stroke; Ischaemic strokes (the artery becomes blocked from an embolus or clot) and haemorrhagic strokes (a vessel bursts, and bleeds into the brain). If the symptoms are temporary, then the event may not be a full stroke but a transient ischaemic attack (TIA).
Risk factors for having a stroke include having a previous TIA, hyperlipidemia, hypertension, age, African-Caribbean ethnicity, and atherosclerosis. The research into strokes is focused on being able to regenerate the lost neurones, and to encourage patients to seek early medical treatment. There is much development into drugs to control to risk factors, which are common in western populations and risk factors for other serious diseases.
Source; Adapted from The Stroke Association
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PubMed Articles
Update carotid artery stenosis.
Stenosis of the extracranial carotid artery is a treatable cause of ischemic stroke and can reliably be detected and graded by vascular ultrasound. The differentiation between symptomatic and asymptom...
INTRODUCTION. From 15 to 30% of all ischemic strokes are cardioembolic. Transthoracic echocardiography plays a key role in the evaluation, diagnosis and management of the embolic source. The absence o...
The direct factor Xa inhibitor apixaban (Eliquis(®)) has predictable pharmacodynamics and pharmacokinetics and does not require routine anticoagulation monitoring. This article reviews the efficacy a...
Rivaroxaban (Xarelto(®)), a direct factor Xa inhibitor, is approved for the prevention of stroke and systemic embolism in patients with atrial fibrillation (AF) in Canada or those with nonvalvular AF...
OBJECTIVE: This study examined clinical, functional, and occupational factors associated with return to work within 18 months after stroke, specifically focusing on the impact of higher cortical dysf...
Transient ischemic attack-like episodes without stroke-like lesions in MELAS.
A stroke-like episode is a core symptom in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Proton magnetic resonance spectroscopy ((1)H-MRS) is useful in the...
The Aphasia Rapid Test: an NIHSS-like aphasia test.
The Aphasia Rapid Test (ART) is a 26-point scale developed as a bedside assessment to rate aphasia severity in acute stroke patients in
The Immune System in Stroke: Clinical Challenges and Their Translation to Experimental Research.
Stroke represents an unresolved challenge for both developed and developing countries and has a huge socio-economic impact. Although considerable effort has been made to limit stroke incidence and imp...
Atherosclerosis is a major pathological process related with several important adverse vascular events including coronary artery disease, stroke, and peripheral arterial disease. Endothelial lipase is...
Child Neurology: Zellweger syndrome.
Zellweger syndrome (ZS) is a severe manifestation of disease within the spectrum of peroxisome biogenesis disorders that includes neonatal adrenoleukodystrophy, infantile Refsum disease, and rhizomeli...
News Articles
Research findings could lead to new therapies for stroke and other brain diseases
Scientists investigating the interaction of a group of proteins in the brain responsible for protecting nerve cells from damage have identified a new target that could increase cell survival.
Age not matter for stroke victims who receive after-stroke intervention strategies
Age has little to do with how patients should be treated after suffering a stroke, according to new research from the University of Georgia.
Patients with moderate to severe periodontal disease now have a new gum disease treatment option available to them. By eliminating periodontitis, laser gum surgery can decrease the risk of other assoc...
Depression Doubles Risk Of Stroke In Middle-Aged Women
Depression doubles the risk of having a stroke in middle-aged women, according to a new study in Stroke: Journal of the American Heart Association. The research, a 12-year examination of 10,547 Austra...
Plasmin Delivered Through A Bubble Is More Effective Than TPA In Busting Clots
A new study from the University of Cincinnati (UC) College of Medicine has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots th...
Study Explores Links Between Depression, Stroke And Age In Women
Brett Smith for redOrbit.com - Your Universe Online In yet another recent study highlighting the connection between mental and physical health, two researchers from the University of Queensland in Au...
New Emergency Stroke Treatments Can Save and Restore Lives if Patients Act Quickly and Call 911
May is National Stroke Awareness Month. Learn the symptoms and act quickly at first signs of stroke. Trenton, NJ (PRWEB) May 17, 2013 Seeking prompt emergency care at the first sign of stroke is more...
Stroke patients respond similarly to after-stroke care, despite age difference
Age has little to do with how patients should be treated after suffering a stroke, according to new research from the University of Georgia.
ACT Collaborates with Southeastern Medical Center on Telestroke Network
Atlanta, GA, May 17, 2013 --(PR.com)-- AcuteCare Telemedicine (ACT), the Southeast region’s largest practice based telemedicine provider, participated at Southeastern Alabama Medical CenterR...
Get With The Guidelines--Stroke program improves patient recovery
People with strokes caused by blood clots fared better in hospitals participating in the Get With The Guidelines--Stroke program according to a study presented at the American Heart Association's Qual...
Events
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Companies
Reverse Medical Corporation is a privately-held medical device company focused on expanding the endovascular management of acute stroke and neurovascular disease. The technology p...
REACH Call is a full-service telemedicine services provider dedicated to eliminating the geographical challenge associated with access to specialized care, bringing time-critical...
Zynex, Inc. (founded in 1996) engineers, manufactures, markets and sells its own design of electrotherapy medical devices in two distinct markets: standard digital electrotherapy...
DecImmune Therapeutics was founded by Michael Carroll PhD (The Immune Disease Institute, Harvard Medical School), and Francis Moore Jr. MD (Brigham and Womenâs Hospital, Harv...
Founded in 1993, SensAble Technologies is the leading developer of 3D touch-enabled (force feedback) solutions and technology that allow users to not only see and hear an on-scree...
Penumbra, Inc. (www.penumbrainc.com) is an independent medical device company committed to delivering clinically beneficial products that help patients suffering from stroke...
Founded in 1993, Sensable remains the leading developer of touch-enabled solutions and technology that allow users to not only see and hear an on-screen computer application, but...
Aetna and The Sunrise Health Hospitals
Sunrise Health is the most technologically advanced hospital network in the central Southwest. Committed to providing the finest healthcare, Sunrise Health includes Sunrise Hospit...
LHP Hospital Group, Inc. and Saint Mary’s Health System
Saint Maryâs Health System is a leading regional healthcare provider anchored by Saint Maryâs Hospital, an acute care community teaching hospital that has served Greater...
America Stem Cell is a privately held biotechnology company based in San Antonio, TX, with offices in San Diego, CA, and is dedicated to the development and commercialization of s...
Clinical Trials
Left Atrial Appendage Occlusion Study II
A pilot, multicentre randomized controlled study of surgical left atrial occlusion (LAA) in 50 patients with atrial fibrillation/flutter undergoing cardiac surgery requiring cardiopulmonar...
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the upper limb are effective in treating spasticity in patients after stroke.
Headache is a common symptom, and patients often seek medical attention at emergency departments due to headaches. The aim of the CoHead Study is to find out if it is possible by measurin...
MAIN AIMS: to analyze the efficacy of nasal CPAP treatment in patients with ischemic first-ever stroke and Sleep Apnea Syndrome (SAS) in terms of: early neurological outcome, functional re...
Efficacy and Safety Study of Cilostazol to Prevent Reoccurrence of Stroke
The study design is subject to relevant SFDA regulations about clinical trials. This indication was approved in Japan in 2003. From the end of May 2004 to the end of Dec. 2004, 720 patien...
Psychosocial/Behavioral Intervention in Post-Stroke Depression
The primary aim of this study is to determine the effect of a nurse-delivered psychosocial/behavioral intervention on reduction of depression in community dwelling post-stroke patients. We...
The study investigates whether endurance training breathing 100% oxygen gives a additional improvement in performance measured as maximal oxygen uptake, compared to training without extra...
CASPAR : Clopidogrel and Acetyl Salicylic Acid in Bypass Surgery for Peripheral ARterial Disease
Primary objective: To evaluate whether clopidogrel 75 mg o.d. versus placebo (on a background of ASA 75-100 mg/d) will lead to an increased rate of primary patency, limb salvage and survi...
Control Strategies of the Locomotor System During Obstacle-Crossing in Stroke Patients
Tripping over obstacles is one of the common movements in daily life and is the most frequently mentioned cause of falls in the elderly. Indeed, crossing obstacles is a more complex motor...
The etiology and pathogenesis of osteoporosis has been extensively discussed. The relationship between bone blood circulation and the formation of bony trabeculae has been less understood...
Videos
Stroke
If you like this animation, LIKE us on Facebook: http://www.nucleusinc.com/facebook http://www.nucleusinc.com/medical-animation This 3D medical animation giv...
Medical and Biotech [MESH] Definitions
Cadasil
A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
National Institute Of Neurological Disorders And Stroke
Component of the NATIONAL INSTITUTES OF HEALTH. It supports and conducts research, both basic and clinical, on the normal and diseases nervous system. It was established in 1950.
Alien Hand Syndrome
An apraxia characterized by the affected limb having involuntary, autonomous, and purposeful behaviors that are perceived as being controlled by an external force. Often the affected limb interferes with the actions of the normal limb. Symptoms develop from lesions in the CORPUS CALLOSUM or medial frontal cortex, stroke, infarction, and neurodegenerative diseases (e.g., CREUTZFELDT-JAKOB SYNDROME, corticobasal degeneration).
Rats, Inbred Shr
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
Reflex, Abdominal
Contractions of the abdominal muscles upon stimulation of the skin (superficial abdominal reflex) or tapping neighboring bony structures (deep abdominal reflex). The superficial reflex may be weak or absent, for example, after a stroke, a sign of upper (suprasegmental) motor neuron lesions. (Stedman, 25th ed & Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p1073)
