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Subacute Sclerosing Panencephalitis SSPE - Biotech, Pharma and Life Science Channel

20:32 EDT 28th July 2014 | BioPortfolio

PubMed Articles [261 Associated PubMed Articles listed on BioPortfolio]

Observations on the Paper "Sclerosing Sertoli Cell Tumor of the Testis: A Clinicopathologic Study of 20 Cases" by Kao et al.

Thecoma of the Ovary: A Report of 70 Cases Emphasizing Aspects of Its Histopathology Different From Those Often Portrayed and Its Differential Diagnosis.

Seventy thecomas of the ovary were evaluated to ascertain their histopathologic spectrum. The tumors occurred over a wide age range (average 49.6 y). Presentation in the form of pelvic or abdominal pa...

Development, characterization and toxicological evaluations of phospholipids complexes of curcumin for effective drug delivery in cancer chemotherapy.

Abstract The purpose of this study was to prepare and characterize the complexes between curcumin (CU) phosphatidylcholine (PC) and hydrogenated soya phosphatidylcholine (HSPC) and to evaluate their a...

Delayed Onset of the Jarisch-Herxheimer Reaction in Doxycycline-Treated Disease: A Case Report and Review of its Histopathology and Implications for Pathogenesis.

: The Jarisch-Herxheimer reaction (JHR) is a transient inflammatory syndrome triggered hours after the start of antibiotic treatment of spirochete infections, namely syphilis. Clinically, JHR manifest...

Age-related degeneration of articular cartilage in the pathogenesis of osteoarthritis: molecular markers of senescent chondrocytes.

Background: Our previous studies demonstrated the expression of procollagen11A1 in fibroblasts of pancreatic cancer desmoplasia and the lack of expression in fibroblasts of pancreatitis by means of th...

Benchmark dose and the three Rs. Part II. Consequences for study design and animal use.

OECD test guidelines for standard toxicity studies prescribe (minimal) numbers of animals, but these are not substantiated by a quantitative analysis of the relationship between number of animals and...

Locomotion Improvement using a Hybrid Assistive Limb in Recovery Phase Stroke Patients.-A Randomized Controlled Pilot Study-

To compare the efficacy of gait training using a single-leg version of the hybrid assistive limb (HAL) on the paretic side to conventional gait training in individuals with subacute stroke.

Monitoring of liver function in the critically ill.

Liver failure and hepatic dysfunction represent diagnostic and therapeutic challenges for the intensivist. Besides acute liver failure, hypoxic hepatitis, sepsis and (secondary) sclerosing cholangitis...

Subretinal Thelazia-Induced Diffuse Unilateral Subacute Neuroretinitis.

Creutzfeldt-Jakob-Like Syndrome due to Hypercalcemic Encephalopathy.

Hypercalcemia can cause a subacute syndrome of progressive dementia and marked changes in the electroencephalogram (EEG). We report a case of iatrogenic hypercalcemia with a close correlation between...

News Articles [29 Associated News Articles listed on BioPortfolio]

Clinical study with Biotie's BTT1023 in primary sclerosing cholangitis awarded external grant funding

Biotie Therapies Corp.          Stock Exchange Release    24 July 2014 at 3.15 p.m. Clinical study with Biotie's BTT1023 in primary sclerosing cholangitis awarded extern...

BRIEF-Biotie Therapies clinical study with BTT1023 awarded external grant funding

July 24 (Reuters) - Biotie Therapies Oyj : * Says clinical study with Biotie's BTT1023 in primary sclerosing cholangitis

Biotie: Selincro enters the market in Spain

BIOTIE THERAPIES CORP.              STOCK EXCHANGE RELEASE     22 July 2014      at 9.00 a.m. Biotie: Selincro enters the market in Spain Biotie today announced tha...

Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

Neurelis Regains Rights to Intranasal Diazepam Program

SAN DIEGO, July 11, 2014 /PRNewswire/ -- Neurelis, Inc. ("Neurelis") today announced an agreement with Biotie Therapies Corp. ("Biotie") to end the option held by Biotie to purchase Neurelis, clearing...

Biotie decides not to exercise option to acquire Neurelis, Inc. but retains economic interest in future success of NRL-1

BIOTIE THERAPIES CORP.     STOCK EXCHANGE RELEASE     11 July 2014 at 9.00 a.m. Biotie decides not to exercise option to acquire Neurelis, Inc. but retains economic interest in futu...

Biotie: Selincro receives positive draft guidance from UK's NICE

BIOTIE THERAPIES CORP.     STOCK EXCHANGE RELEASE                  10 July, 2014 at 1.00 p.m. Biotie: Selincro receives positive draft guidance from UK's NICE B...

Drinking coffee, smoking may protect against cholangitis

(HealthDay)—Coffee consumption and smoking might protect against the development of primary sclerosing cholangitis (PSC), according to a study published in the June issue of Clinical Gastroenterolog...

Use of Whole-Exome Sequencing to Determine the Genetic Basis of Multiple Mitochondrial Respiratory Chain Complex Deficiencies

ImportanceMitochondrial disorders have emerged as a common cause of inherited disease, but their diagnosis remains challenging. Multiple respiratory chain complex defects are particularly difficult to...

Hospital and Healthsystem Association of PA (HAP) endorses VisiQuate analytics solutions for key decision makers at all levels of the enterprise

Traditionally, business analytics have been point solutions for specialized decision makers. But now, Pennsylvania hospitals and healthcare organizations will have access to analy...

Events [0 Results]

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Companies [1 Associated Companies listed on BioPortfolio]

Albert Einstein Healthcare Network

Albert Einstein Healthcare Network is a 1,200 bed integrated delivery network with nearly 7,400 employees serving the communities of North Philadelphia and Montgomery County, PA....

Clinical Trials [77 Associated Clinical Trials listed on BioPortfolio]

Evaluation of Treated and Untreated Stroke

This project will investigate the evolution of treated and untreated stroke in patients recruited from the collaborative brain stroke program between NINDS, CC, and Suburban Hospital. The...

Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis

OBJECTIVES: I. Assess the safety and effectiveness of budesonide in patients with primary sclerosing cholangitis or primary biliary cirrhosis experiencing a suboptimal response to ursode...

Evaluation of Subacute Rehabilitative Care

Prior rehabilitation outcome studies had many weaknesses. They had: a) evaluated rehabilitation effects only in isolated subgroups, b) focused on functional ability rather than on quality...

Effects of Strength Training on Upper-Limb Function in Post-Stroke Hemiparesis

Our overall goal is to develop therapeutic interventions to improve upper-limb motor function in hemiparetic persons based on an improved understanding of the mechanisms responsible for it...

Trial of High-dose Urso in Primary Sclerosing Cholangitis

This is a multicenter, randomized, controlled trial of high dose ursodiol versus placebo for patients with primary sclerosing cholangitis (PSC). The average duration of follow-up will be...

Trial of Drainage With or Without Bleomycin Instillation for Malignant Pericardial Effusion

The purpose of this study is to evaluate the efficacy of pericardial instillation of bleomycin as a sclerosing agent after pericardial drainage for lung cancer-associated malignant pericar...

Below Study - Balloonangioplasty or Stents With ReoPro for Prevention of Subacute Reocclusion in Arteries Below the Knee

The Below-Study is a randomized, prospective mono-centre trial on the efficacy and safety the adjunctive use of a GP IIb/IIIa antagonist for prevention of early reocclusion in arterial bel...

Nasal Potential Difference (NPD) Testing: Evaluation of CFTR Function in Children With Primary Sclerosing Cholangitis (PSC)

The investigators hypothesize that PSC in children is associated with mutations and functional changes of the cystic fibrosis (CF) gene.

Anticipatory Muscle Control and Effect of Stabilizing Exercises in Patients With Subacute and Chronic Low Back Pain

Muscular stability is essential to the spinal column to avoid harmful strain and injury to its structures. Sudden postural disturbances impose reactive internal forces through the spine. I...

Tc-99m Renography and Cisplatin-Induced Nephrotoxicity

Cisplatin is a heavy-metal complex widely used in the treatment of a variety of malignancies, including small cell and non-small cell lung cancer, ovarian, bladder, head and neck, esophage...

Medical and Biotech [MESH] Definitions

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

The sodium salts of the fatty acids in cod liver oil; an irritant and sclerosing agent used to treat varicose veins and arthritic joints.

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