Subacute Sclerosing Panencephalitis SSPE - Biotech, Pharma and Life Science Channel

07:52 EDT 28th April 2015 | BioPortfolio

PubMed Articles [219 Associated PubMed Articles listed on BioPortfolio]

Glutamate and GABA Imbalance Following Traumatic Brain Injury.

Traumatic brain injury (TBI) leads to multiple short- and long-term changes in neuronal circuits that ultimately conclude with an imbalance of cortical excitation and inhibition. Changes in neurotrans...

Cystic Fibrosis below the Diaphragm: Abdominal Findings in Adult Patients.

Cystic fibrosis (CF) is the most common lethal autosomal recessive disease in the white population. Mutation of the CF transmembrane conductance regulator gene on chromosome 7 results in production of...

Endoscopic hematoma evacuation for acute and subacute subdural hematoma in elderly patients.

OBJECT Endoscopic surgery was performed for acute or subacute subdural hematoma (SDH), and its effectiveness and safety in elderly patients were evaluated. METHODS Between September 2007 and November ...

Successful treatment of IgG-4 related sclerosing disease with rituximab: a novel case report.

IgG4-related sclerosing disease (IgG4-RSD) is a rare inflammatory disease that can affect multi organs. We describe a paediatric patient with ocular, nerve, and renal involvement successfully treated ...

Ki-67 expression in sclerosing adenosis and adjacent normal breast terminal ductal lobular units: a nested case-control study from the Mayo Benign Breast Disease Cohort.

Sclerosing adenosis (SA) increases risk for invasive breast cancer (BC) 2.1 times relative to that in the general population. Here, we sought to evaluate whether the proliferation marker Ki-67 stratif...

Trunk Motor Control Deficits in Acute and Subacute Low Back Pain are Not Associated with Pain or Fear of Movement.

A subgroup of patients with acute/sub-acute low back pain (LBP) presenting with trunk movement control deficits, pain provocation with segmental testing, and segmental hypermobility have been clinical...

Mania as a presenting clinical feature of subacute sclerosing panencephalitis.

Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice.

There is much evidence to suggest that brain-derived neurotrophic factor (BDNF) is a prominent candidate in promoting neuroprotection, axonal regeneration, and synaptic plasticity following spinal cor...

Peritoneal Decortication: An Innovative Technique for Treatment of Obstructive Sclerosing Encapsulating Peritonitis.

Periadnexal Mucin as an Additional Histopathologic Feature of Chronic Eczematous Dermatitis.

Cutaneous mucinoses are a heterogeneous group of disorders characterized by an abnormal amount of mucin in the skin. However, the pathomechanism of an excessive mucin deposition in the skin is still u...

News Articles [34 Associated News Articles listed on BioPortfolio]

Biotie provides update on tozadenant Phase 3 program

BIOTIE THERAPIES CORP.     STOCK EXCHANGE RELEASE                 23 April 2015 at 10.15 a.m. Biotie provides update on tozadenant Phase 3 program Biotie has furthe...

Fatigue in persons with subacute spinal cord injury who are dependent on a manual wheelchair

The Challenges Surrounding Primary Sclerosing Cholangitis

In navigating issues such as differential diagnoses and a confounding lack of clear treatment options, clinicians are best suited by following the most recent guidelines in this area. Medscape Gastr...

Priority Review erases Shire's losses on trial miss

Shire plc (LSE:SHP; NASDAQ:SHPG) turned early losses on clinical data into gains on Thursday, picking up $7.24 to $254.32 on NASDAQ after FDA accepted for filing and granted Priority Review to an NDA ...

Astellas Teams Up with The Chris Klug Foundation on the Bounce Back Award to Recognize Extraordinary Transplant Recipients

NORTHBROOK, Ill. and ASPEN, Colo., April 1, 2015 /PRNewswire/ -- Astellas Pharma US, Inc., in partnership with the Chris Klug Foundation (CKF), is pleased to sponsor the second annual Bounce...

Biotie announces start of patient enrolment into Phase 2a clinical study with BTT1023 in primary sclerosing cholangitis

Biotie Therapies Corp.          Stock Exchange Release    31 March 2015 at 9.00 am Biotie announces start of patient enrolment into Phase 2a clinical study with BTT1023 in pr...

BRIEF-Biotie announces start of patient enrolment into Phase 2a clinical study with BTT1023

* Announces start of patient enrolment into Phase 2a clinical study with BTT1023 in primary sclerosing cholangitis

Biotie Therapies Oyj: Biotie announces start of patient enrolment into Phase 2a clinical study with BTT1023 in primary sclerosing cholangitis

Biotie Therapies Corp. Stock Exchange Release 31 March 2015 at 9.00 am Biotie announces start of patient enrolment into Phase 2a clinical study with BTT1023 in primary sclerosing cholangitis Bioti...

Change in Biotie Therapies' Annual General Meeting 2015

BIOTIE THERAPIES CORP.                  Stock Exchange Release            20 March 2015 at 9.00 am Change in Biotie Therapies' Annual General Meeting 201...

Correction: Biotie's Financial Statement Report and Corporate Governance Statement 2014 published

BIOTIE THERAPIES CORP.    STOCK EXCHANGE RELEASE                  9 March 2015 at 5:45 p.m. Correction: Biotie's Financial Statement Report and Corporate Governance Stat...

Events [0 Results]

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Companies [1 Associated Companies listed on BioPortfolio]

Albert Einstein Healthcare Network

Albert Einstein Healthcare Network is a 1,200 bed integrated delivery network with nearly 7,400 employees serving the communities of North Philadelphia and Montgomery County, PA. ...

Clinical Trials [85 Associated Clinical Trials listed on BioPortfolio]

To Determine the Therapeutic Effect of the Music Glove and Conventional Hand Exercises to Subacute Stroke Patients

The investigators are trying to determine the therapeutic effect of the music glove and conventional hand exercise program to the subacute stroke patients. All participants will be random...

Managing Non-acute Low Back Symptoms in Occupational Health: Two Trials

The purpose of this study is: - Epidemiological part: characteristics of low back pain patients from a forestry company in Finland. Data is collected from occupational health data...

Development of a Patient-Reported Outcome Measure to Assess Symptoms in Patients With Primary Sclerosing Cholangitis (PSC)

The objectives of this qualitative study are to elicit concepts about symptoms that are important to patients with primary sclerosing cholangitis (PSC), as well as the key impacts of sympt...

Prevention of Retained-Blood Outcomes With Active Clearance Technology

Postoperative bleeding is a common consequence after heart surgery which can significantly impact outcomes and costs [Wynne R, Christensen MC, Dixon B]. When bleeding occurs, reliable post...

Fractional Concentration of Exhaled NO(FENO) to Direct Montelukast Treatment of Sub-acute Cough

Cough is a common symptom of respiratory medicine clinic patients, which has complex etiology and wide-ranging. Cough is usually divided into three categories by time: acute cough, subacut...

Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease

Patients (male or female) with either documented genetically confirmed diagnosis of inherited mitochondrial diseases, who are ≥ 2 years old and < 18 years, and meet other specified inclu...

Robotic-assisted Gait Training Combined With Transcranial Direct Current Stimulation to Maximize Gait Recovery After Stroke

1. Study objective To evaluate the effect of robotic-assisted gait training combined with transcranial direct current stimulation (tDCS) as compared to that of robotic-assisted g...

A Pilot Study of Xifaxan to Treat Patients With PSC

In the current protocol, we propose the assessment of potential beneficial effects of the antibiotic Xifaxan on liver biochemistries, liver related symptoms and Mayo risk score in 15 adult...

Effects and Mechanisms of Treatment Intensity of Mirror Therapy in Patients With Subacute Stroke

The purpose of this study will evaluate the long-term benefits, optimal dose and mechanisms of mirror therapy and its effects on physiological markers.

PEG-Glucocerebrosidase for the Treatment of Gaucher Disease

Gaucher disease is a lysosomal storage disease resulting from glucocerebroside accumulation in macrophages due to a genetic deficiency of the enzyme glucocerebrosidase. It may occur in pa...

Medical and Biotech [MESH] Definitions

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

The sodium salts of the fatty acids in cod liver oil; an irritant and sclerosing agent used to treat varicose veins and arthritic joints.

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