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Subacute Sclerosing Panencephalitis SSPE - Biotech, Pharma and Life Science Channel

14:54 EDT 23rd June 2017 | BioPortfolio

PubMed Articles [200 Associated PubMed Articles listed on BioPortfolio]

From dizziness to severe ataxia and dysarthria: New cases of anti-Ca/ARHGAP26 autoantibody-associated cerebellar ataxia suggest a broad clinical spectrum.

In 2010, a novel anti-neuronal autoantibody, termed anti-Ca, was described in a patient with subacute cerebellar ataxia, and Rho GTPase-activating protein 26 (ARHGAP26) was identified as the target an...

Sexual dimorphism in the inflammatory response to traumatic brain injury.

The activation of resident microglial cells, alongside the infiltration of peripheral macrophages, are key neuroinflammatory responses to traumatic brain injury (TBI) that are directly associated with...

Imaging of Acute Capsuloligamentous Sports Injuries in the Ankle and Foot: Sports Imaging Series.

The ankle and foot are commonly injured during sporting activities. Clinical diagnosis can at times be challenging, due to the complex anatomy and multiple sites of potential injury. In the athlete, t...

Lack of efficacy of infliximab in the treatment of primary sclerosing cholangitis in inflammatory bowel diseases in childhood.

Sclerosing Aortic and Coronary Arteritis Due to IgG4-Related Disease.

We present the case of a 55-year-old woman admitted for a coronary artery bypass operation because of three-vessel coronary artery disease based on angiographic findings and clinical symptoms. Unexpec...

vWF correlates with visceral and pericardial adipose tissue in patients with a recent stroke of suspected cardiogenic etiology.

A chronically elevated level of von Willebrand factor (vWF) is a common finding in patients with cardiovascular diseases. Obesity is a well-recognized risk factor for thrombotic cardiovascular complic...

Hemodynamic Findings of Severe Subacute Aortic Regurgitation.

The hemodynamic features of subacute aortic regurgitation include equalization of the left ventricular pressure and the aortic pressure during diastole, a mildly increased pulse pressure, and systemic...

Loss of Hepatic Lrpprc Alters Mitochondrial Bioenergetics, Regulation of Permeability Transition and Trans-Membrane Ros Diffusion.

The French-Canadian variant of Leigh Syndrome (LSFC) is an autosomal recessive oxidative phosphorylation (OXPHOS) disorder caused by a mutation in LRPPRC, coding for a protein involved in the stabilit...

Comparative Clinical Characteristics and Natural History of Three Variants of Sclerosing Cholangitis: IgG4-Related SC, PSC/AIH and PSC alone.

There is increased interest and recognition of the clinical variants of Sclerosing Cholangitis (SC) namely IgG4-SC, PSC/AIH overlap and PSC. For most Centers, the characteristic of IgG4-SC has not bee...

Autoantibodies to nodal isoforms of neurofascin in chronic inflammatory demyelinating polyneuropathy.

Chronic inflammatory demyelination polyneuropathy is a heterogeneous and treatable immune-mediated disorder that lacks biomarkers to support diagnosis. Recent evidence indicates that paranodal protein...

News Articles [32 Associated News Articles listed on BioPortfolio]

Caspase 6 Apoptotic Protease Mch 2 or CASP6 or EC 3.4.22.59 Pipeline Review, H1 2017 [Updated: 20062017] Prices from USD $3500

Caspase 6 Apoptotic Protease Mch 2 or CASP6 or EC 3.4.22.59 Pipeline Review, H1 2017SummaryAccording to the recently published report 'Caspase 6 Pipeline Review, H1 2017'; Caspase 6 Apoptotic Protea...

AbilityLinks Launches Newly Renovated Website to Promote Hiring of People with Disabilities

WHEATON, Ill., June 15, 2017 /PRNewswire-USNewswire/ -- Celebrating its 16th anniversary this year, AbilityLinks.org, the award-winning job-opportunity network, is completely renovating its websi...

Primary sclerosing cholangitis: Ursodeoxycholic acid derivative: safe and effective

Ulcerative Colitis Forecast in 8 Major Markets 20162026 [Updated: 01022016] Prices from USD $6100

Black Swan Analysis Epiomic Epidemiology Series Forecast Report on Ulcerative Colitis in 8 Major MarketsUlcerative Colitis UC is an inflammatory bowel disease IBD causing chronic inflammation in the c...

AIVITA Comments on Positive Findings from Asterias' SCiStar Trial for Spinal Cord Injury

IRVINE, Calif., June 13, 2017 /PRNewswire/ -- AIVITA Biomedical offered its congratulations today following the announcement of positive 9-month efficacy and safety data from Asterias Biotherapeu...

Initial successes in treating a hitherto incurable liver disorder

Primary sclerosing cholangitis is a currently incurable liver disorder, primarily affecting younger adults aged between 30 and 40. A European multi-centre Phase II study led by MedUni Vienna in close ...

'We’ve said for a long time that this was going to happen': a Q&A with Patsy Stinchfield on Minnesota's measles epidemic

Susan Perry Minnesota’s measles epidemic is not yet over.“We had reached a lull in the outbreak, with no new exposures being recorded for m...

“IMatter” Campaign Launches in Celebration of National Nursing Home Week

Music Video Produced by Staff at The Grove at Valhalla Rehabilitation and Nursing Center (CareRite Centers) to Support Skilled Nursing Care and Nursing Home Colleagues ...

Primary sclerosing cholangitis

Genesis HealthCare Corp GEN Pharmaceuticals Healthcare Deals and Alliances Profile [Updated: 25042017] Prices from USD $250

SummaryGenesis HealthCare Corp Genesis HealthCare is a healthcare company that provides nursing and rehabilitation therapy. The company offers services such as rehabilitation therapy, ventilator care,...

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Companies [2 Associated Companies listed on BioPortfolio]

CareRite Centers, LLC

With locations in New York, New Jersey, Pennsylvania, Ohio and Florida, CareRite Centers is committed to excellence and superior quality of care, offering stellar subacute rehabil...

Albert Einstein Healthcare Network

Albert Einstein Healthcare Network is a 1,200 bed integrated delivery network with nearly 7,400 employees serving the communities of North Philadelphia and Montgomery County, PA. ...

Clinical Trials [160 Associated Clinical Trials listed on BioPortfolio]

Use Lay Language. CAA-ri : a Series of 28 Patients

INTRODUCTION: Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a very rare manifestation of cerebral amyloid angiopathy, characterized by acute/subacute neurological deteriorat...

Endovascular Revascularization of Symptomatic Chronically Occluded Internal Carotid Artery

Ischemic stroke is the fourth leading cause of disability and mortality in the United States. The overall risk of emboli detachment from a chronically occluded internal carotid artery (COI...

Task-specificity for Locomotor Recovery Following SCI

The primary goal of the proposed study is to identify the contributions of the amount of task-specific practice on locomotor (i.e., walking) recovery in patients with chronic (> 1 yr) moto...

Phase II Study to Evaluate the Efficacy and Safety of ZL-3101 in Subjects With Subacute Eczema

This is a double-blind, randomized, placebo-controlled multi-center phase IIA study to evaluate the clinical efficacy and safety of Fugan ointment versus placebo applied to involved skin o...

Sensory-driven Motor Recovery in Poorly Recovered Subacute Stroke Patients

This research project addresses a scientifically important question that cannot be answered by other means. The use of peripheral nerve stimulation has the potential to enhance recovery in...

The Treatment Effectiveness of Combined tDCs and Neurofeedback (NF) for Patients With Cognitive Deficits After Stroke

This is a double blinded, randomized control trial with a pretest-posttest control and interventional groups design. Both the assessor and participants are blinded to all assessments and e...

Antibiotics to Decrease Post ERCP Cholangitis

Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic procedure used to treat bile duct stones, obstructive jaundice, biliary leaks, and a variety of other conditions. ...

Immersive Virtual Reality Based Training for Rehabilitation of Subacute Stroke

The investigators will conduct a single-blind, randomized controlled trial of 60 patients with subacute stroke. Patients will be randomly assigned into a control group and an intervention ...

Intraarterial Stem Cells in Subacute Ischemic Stroke

Stroke is a leading cause of morbidity and mortality.Acute ischemia causes irreversible damage to neurons and glial cells, leading to functional deficits and chronic sequelae with variable...

"Overlap Syndrome and PSC: Evaluating Role of Gut Microflora and Its Identification With Antibiotics in Children"

Based upon the possible implication of microbiota and abnormal microbial metabolites such as altered bile acids, in the pathogenesis of PSC, emerging data suggests that oral antibiotics, s...

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Medical and Biotech [MESH] Definitions

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

The sodium salts of the fatty acids in cod liver oil; an irritant and sclerosing agent used to treat varicose veins and arthritic joints.

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