Subacute Sclerosing Panencephalitis SSPE - Biotech, Pharma and Life Science Channel

17:43 EST 1st February 2015 | BioPortfolio

PubMed Articles [244 Associated PubMed Articles listed on BioPortfolio]

IgG4-related sclerosing cholangitis in the absence of autoimmune pancreatitis mimicking extrahepatic cholangiocarcinoma.

Abstract Aims. IgG4-related sclerosing cholangitis in extrahepatic bile ducts in the absence of autoimmune pancreatitis (AIP) is rare and is poorly studied. Herein, we present the clinicopathological ...

Colorectal cancer and cholangiocarcinoma in patients with primary sclerosing cholangitis and inflammatory bowel disease.

Abstract Objective. Inflammatory bowel disease (IBD) patients with concomitant primary sclerosing cholangitis (PSC) carry an increased risk of colorectal cancer (CRC) and cholangiocarcinoma (CCA). We ...

Isolated intrapancreatic IgG4-related sclerosing cholangitis.

Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is frequently associated with type 1 autoimmune pancreatitis (AIP). Association with AIP can be utilized in the diagnosis of IgG4-SC. However...

Q Wave in the Inferior Leads: There Is More Than Scar.

Q waves can regularly be observed in the 12-lead electrocardiogram either due to heart axis underlying pathology such as subacute myocardial infarction, myocardial scar, or accessory pathways. Rarely,...

Advocating Nonsurgical Management of Patients With Small, Incidental Radial Scars at the Time of Needle Core Biopsy: A Study of 77 Cases.

Context .- Radial scars are benign sclerosing lesions that are routinely excised when diagnosed in a needle core biopsy. Optimal management for patients with incidental and small (≤5 mm) radial scar...

Subacute myocardial infarction due to long-term paint thinner and ecstasy abuse.

Comparison of intraductal ultrasonography findings between primary sclerosing cholangitis and IgG4-related sclerosing cholangitis.

Comparisons of intraductal ultrasonography (IDUS) findings between primary sclerosing cholangitis (PSC) and IgG4-related sclerosing cholangitis (IgG4-SC) have not been elucidated. We aimed to clarify ...

The role of TRPV1 channels in carrageenan-induced mechanical hyperalgesia in mice.

Peripheral inflammation leads to ipsilateral and contralateral mechanical hyperalgesia. The transient receptor potential channel vanilloid type 1 (TRPV1), a nonselective cation channel expressed in ma...

Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature.

Patients diagnosed with juvenile-onset systemic lupus erythematosus (JSLE) often have skin and oral lesions as part of their presentation. These mucocutaneous lesions, as defined by the American Colle...

Meta-analysis of Duct to duct versus Roux en Y biliary reconstruction following Liver Transplantation for Primary Sclerosing Cholangitis (PSC).

This meta-analysis aimed to compare outcomes following bile duct reconstruction in patients with primary sclerosing cholangitis (PSC) undergoing liver transplantation depending on whether duct-to du...

News Articles [37 Associated News Articles listed on BioPortfolio]

Intercept provides OCA clinical update

Intercept Pharmaceuticals Inc. (NASDAQ:ICPT) gained $6.78 to $152.70 on Tuesday after updating investors on its clinical development plans for OCA obeticholic acid to treat liver diseases.In December,...

Unexpected complication in a rat stroke model: exacerbation of secondary pathology in the thalamus by subacute intraarterial administration of human bone marrow-derived mesenchymal stem cells

First Sancilio Lipidology Symposium

First Sancilio & Company Lipidology Symposium To Be Held in South Florida Jupiter, FL (PRWEB) January 07, 2015 Top experts in lipidology and lipidomics from around the nation and world will gathe...

BMS extends fibrosis research with Calibr collaboration

Bristol-Myers Squibb has unveiled a new research collaboration in the area of anti-fibrotic therapies, an area tipped for huge market growth.The US pharma company is to work with the California Instit...

BIOTIE ANNOUNCES START OF SYN120 PHASE 2A TRIAL IN PARKINSON'S DISEASE DEMENTIA AND PROVIDES OUTLOOK UPDATE FOR NEAR TERM PIPELINE EVENTS

BIOTIE THERAPIES CORP.     STOCK EXCHANGE RELEASE                  23 December, 2014 at 9.30 a.m. BIOTIE ANNOUNCES START OF SYN120 PHASE 2A TRIAL IN PARKINSON'S...

Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke

Vein Techniques Presentation Given at Annual American Society of Dermatologic Surgery Meeting

Expert dermatologist Dr. Mitchel Goldman of Cosmetic Laser Dermatology headed a live demonstration about advanced sclerotherapy and vein techniques San Diego, CA (PRWEB) December 11, 2014 At the annu...

Anticoagulation seen in about half of sub-segmental PE cases

(HealthDay)—Sub-segmental pulmonary embolism (SSPE) represents a substantial burden of total pulmonary embolisms (PEs), according to research published online Dec. 1 in the Journal of Thrombosis and...

Biotie Therapies Corp. (BTH1V) - Pharmaceuticals & Healthcare - Deals and Alliances Profile

Recently added to the BioPortfolio report store, Biotie Therapies Corp. (BTH1V) - Pharmaceuticals & Healthcare - Deals and Alliances Profile is a new report from GlobalData published on 2014-11-1...

Colon Neoplasia More Common in UC-PSC Than Crohn's-PSC

Patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC) may have a more severe disease course and a greater risk of colon neoplasia and colectomy, than patients with PSC and Cro...

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Companies [1 Associated Companies listed on BioPortfolio]

Albert Einstein Healthcare Network

Albert Einstein Healthcare Network is a 1,200 bed integrated delivery network with nearly 7,400 employees serving the communities of North Philadelphia and Montgomery County, PA. ...

Clinical Trials [83 Associated Clinical Trials listed on BioPortfolio]

Development of a Patient-Reported Outcome Measure to Assess Symptoms in Patients With Primary Sclerosing Cholangitis (PSC)

The objectives of this qualitative study are to elicit concepts about symptoms that are important to patients with primary sclerosing cholangitis (PSC), as well as the key impacts of sympt...

Fractional Concentration of Exhaled NO(FENO) to Direct Montelukast Treatment of Sub-acute Cough

Cough is a common symptom of respiratory medicine clinic patients, which has complex etiology and wide-ranging. Cough is usually divided into three categories by time: acute cough, subacut...

Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease

Patients (male or female) with either documented genetically confirmed diagnosis of inherited mitochondrial diseases, who are ≥ 2 years old and < 18 years, and meet other specified inclu...

Robotic-assisted Gait Training Combined With Transcranial Direct Current Stimulation to Maximize Gait Recovery After Stroke

1. Study objective To evaluate the effect of robotic-assisted gait training combined with transcranial direct current stimulation (tDCS) as compared to that of robotic-assisted g...

A Pilot Study of Xifaxan to Treat Patients With PSC

In the current protocol, we propose the assessment of potential beneficial effects of the antibiotic Xifaxan on liver biochemistries, liver related symptoms and Mayo risk score in 15 adult...

Effects and Mechanisms of Treatment Intensity of Mirror Therapy in Patients With Subacute Stroke

The purpose of this study will evaluate the long-term benefits, optimal dose and mechanisms of mirror therapy and its effects on physiological markers.

PEG-Glucocerebrosidase for the Treatment of Gaucher Disease

Gaucher disease is a lysosomal storage disease resulting from glucocerebroside accumulation in macrophages due to a genetic deficiency of the enzyme glucocerebrosidase. It may occur in pa...

Evaluation of Treated and Untreated Stroke

This project will investigate the evolution of treated and untreated stroke in patients recruited from the collaborative brain stroke program between NINDS, CC, and Suburban Hospital. The...

Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis

OBJECTIVES: I. Assess the safety and effectiveness of budesonide in patients with primary sclerosing cholangitis or primary biliary cirrhosis experiencing a suboptimal response to ursode...

Evaluation of Subacute Rehabilitative Care

Prior rehabilitation outcome studies had many weaknesses. They had: a) evaluated rehabilitation effects only in isolated subgroups, b) focused on functional ability rather than on quality ...

Medical and Biotech [MESH] Definitions

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

The sodium salts of the fatty acids in cod liver oil; an irritant and sclerosing agent used to treat varicose veins and arthritic joints.

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