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Subacute Sclerosing Panencephalitis SSPE - Biotech, Pharma and Life Science Channel

10:40 EST 3rd December 2016 | BioPortfolio

PubMed Articles [179 Associated PubMed Articles listed on BioPortfolio]

Do subjects with acute/subacute temporomandibular disorder have associated cervical impairments: A cross-sectional study.

There is preliminary evidence of cervical musculoskeletal impairment in some temporomandibular disorder (TMD) pain states.

Neurochemical changes following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury: A microdialysis study.

Energy metabolic dysfunction is a key determinant of cellular damage following traumatic brain injury and may be worsened by additional insults. This study evaluated the acute/subacute effects of comb...

The WHO 2016 Classification of Testicular Non-Germ Cell Tumours: A Review and Update from the International Society of Urological Pathology Testis Consultation Panel.

The World Health Organization (WHO) released a new tumour classification for the genitourinary system in early 2016 after consensus by pathologists with expertise in these organs. It utilized the fram...

WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats.

With-no-lysine kinase (WNK) and Na(+)-K(+)-2Cl(-) cotransporter 1 (NKCC1) are involved in the pathogenesis of hypertension. In this study, we investigated the WNK-NKCC1 signaling pathway in spontaneou...

Characterization of the antibody response after cervical spinal cord injury.

The immune system plays a critical and complex role in the pathobiology of spinal cord injury (SCI), exerting both beneficial and detrimental effects. Increasing evidence suggests that there are injur...

Overground gait training using a motorized assistive device in patients with severe disabilities after stroke.

Regaining of the patient's ability to walk after stroke is an important goal of rehabilitation programmes. The ultimate goal of gait rehabilitation is to empower patients for overground walking. We ha...

Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis.

Routine childhood vaccination against measles, mumps and rubella has virtually abolished virus-related morbidity and mortality. Notwithstanding this, we describe here devastating neurological complica...

Heparin-binding epidermal growth factor-like growth factor and hepatocyte growth factor inhibit cholestatic liver injury in mice through different mechanisms.

In contrast to hepatocyte growth factor (HGF), the therapeutic potential and pathophysiologic roles of heparin-binding epidermal growth factor-like growth factor (HB-EGF) in liver diseases remain re...

Subacute cardiac rubidium-82 positron emission tomography ((82)Rb-PET) to assess myocardial area at risk, final infarct size, and myocardial salvage after STEMI.

Determining infarct size and myocardial salvage in patients with ST-segment elevation myocardial infarction (STEMI) is important when assessing the efficacy of new reperfusion strategies. We investiga...

Depression and anxiety symptoms are associated to disruption of default mode network in subacute ischemic stroke.

Depression and anxiety symptoms are common after stroke and associated to reduction in quality of life and poor physical and social outcomes. The Default Mode Network (DMN) plays an important role in ...

News Articles [53 Associated News Articles listed on BioPortfolio]

Thyroid sclerosing mucoepidermoid carcinoma with eosinophilia: a clinicopathologic and molecular analysis of a distinct entity

Acute and SubAcute Bursitis Global Clinical Trials Review, H2, 2015 Prices from USD $2500

Acute and SubAcute Bursitis Global Clinical Trials Review, H2, 2015SummaryGlobalData's clinical trial report, Acute and SubAcute Bursitis Global Clinical Trials Review, H2, 2015" provides an overview ...

China Health Food Manufacturing Industry Overview, 20112020 Prices from USD $1800

DescriptionHealth food refers to the food claimed to have certain health care functions or supplement vitamin and minerals. That is to say, the food is suitable for certain people to regulate the body...

Curable initiates the international PSC Genome project

Biospectrum The Regeneron Genetics Center aims to sequence 5,000 or more primary sclerosing cholangitis (PSC) patients ...

Curable initiates the International PSC Genome project in partnership with the Mayo Clinic

The Regeneron Genetics Center aims to sequence 5000 or more primary sclerosing cholangitis (PSC) patients, Mayo Clinic is contributing DNA samples from more than 1000 PSC patients

Intercept Pharmaceuticals, Inc. ICPT Pharmaceuticals Healthcare Deals and Alliances Profile Prices from USD $250

SummaryIntercept Pharmaceuticals, Inc. Intercept is a biopharmaceutical company that researches, develops and commercializes treatments for chronic liver and intestinal diseases. It develops products ...

Primary Sclerosing Cholangitis Global Clinical Trials Review, H2, 2015 Prices from USD $2500

Primary Sclerosing Cholangitis Global Clinical Trials Review, H2, 2015SummaryGlobalData's clinical trial report, Primary Sclerosing Cholangitis Global Clinical Trials Review, H2, 2015" provides an ove...

Genesis HealthCare Corporation GEN Pharmaceuticals Healthcare Deals and Alliances Profile Prices from USD $250

SummaryGenesis HealthCare Corporation Genesis HealthCare is a pharmaceutical company that provides nursing and rehabilitation therapy. The company offers services such as rehabilitation therapy, venti...

Subacute Sclerosing Panencephalitis

Subacute sclerosing panencephalitis is a lethal complication of measles that is not as rare as previously believed.

Mayo Clinic, Regeneron Genetics Center Join Accelerator in Sequencing Project for PSC

Aiming to conduct the largest sequencing project for primary sclerosing cholangitis (PSC) to date, the nonprofit research accelerator Curable has partnered with the Regeneron Genetics Center (RGC) and...

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Companies [1 Associated Companies listed on BioPortfolio]

Albert Einstein Healthcare Network

Albert Einstein Healthcare Network is a 1,200 bed integrated delivery network with nearly 7,400 employees serving the communities of North Philadelphia and Montgomery County, PA. ...

Clinical Trials [141 Associated Clinical Trials listed on BioPortfolio]

A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis

The purpose of this study is to determine whether curcumin, a drug and naturally-occurring plant compound, is safe and effective in the treatment of primary sclerosing cholangitis (PSC).

ADMSCs for the Treatment of Systemic Sclerosis

Systemic sclerosis (SSc) is a rare autoimmune disease, mainly characterized by cutaneous and visceral fibrosis. Digital ulcer and sclerosing skin are commonly affected on hands, but the tr...

"Remind-to-move" for Promoting Upper Extremity Recovery in Patients With Stroke After Subacute Discharge

This is a multi-centered randomized controlled trial to investigate the effects of "Remind-to-Move" (RTM) using wearable devices at home for promoting upper extremity recovery in stroke pa...

Safety, Tolerability, and Efficacy of GS-9674 in Adults With Primary Sclerosing Cholangitis Without Cirrhosis

The primary objective of this study is to evaluate the safety and tolerability of GS-9674 in adults with primary sclerosing cholangitis (PSC).

Evaluation of Systemic Microvascular Endothelial Dysfunction in Patients Presenting With Infective Endocarditis

Infective endocarditis (IE) is a severe clinical condition with a high in-hospital and 5-year mortality. It has a growing incidence, both related to healthcare and possibly to changes in p...

Effect of Phenytoin on the Ganglion Cell Inner Plexiform Layer and Visual Field in Patients With an Acute Optic Neuritis

Optic neuritis typically occurs in young (mean age, 32 years), female (77%) patients, and it presents as subacute monocular visual loss that develops over several days. As yet, treatment ...

Powered Exoskeleton for the Treatment of Elbow Spasticity

This is a phase-II clinical study to assess whether intense passive mobilization of the elbow during the early stage is effective in preventing spasticity from occurring at a later stage. ...

Combined tDCS and Vision Restoration Training in Subacute Stroke Rehabilitation: A Pilot Study

The purpose of this Study is to determine whether non-invasive transcranial direct current stimulation (tDCS) is effective in increasing rehabilitation effects after stroke in visual Corte...

Cerebral Haemodynamics in Stroke Thrombolysis Study (CHIST)

Cerebral autoregulation is an important mechanism whereby cerebral perfusion is normally maintained at a constant level, over a relatively wide blood pressure range. It can be assessed non...

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of GSK2646264 in Cutaneous Lupus Erythematosus Patients

This study is designed to examine safety, tolerability, pharmacokinetics, pharmacodynamics and clinical effect of repeat dosing of GSK2646264 in patients with subacute and chronic cutaneou...

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Medical and Biotech [MESH] Definitions

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

The sodium salts of the fatty acids in cod liver oil; an irritant and sclerosing agent used to treat varicose veins and arthritic joints.

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