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Subacute Sclerosing Panencephalitis SSPE - Biotech, Pharma and Life Science Channel

13:04 EST 18th January 2017 | BioPortfolio

PubMed Articles [191 Associated PubMed Articles listed on BioPortfolio]

18F-FDG PET/CT Features of Chronic Sclerosing Sialadenitis Presenting as Localized IgG4-Related Disease.

Chronic sclerosing sialadenitis is a benign inflammatory condition that most commonly affects the submandibular gland in elderly individuals. It is currently known to belong to the spectrum of IgG4-re...

Content of conventional therapy for the severely affected arm during subacute rehabilitation after stroke: An analysis of physiotherapy and occupational therapy practice.

Physiotherapy (PT) and occupational therapy (OT) are key professions providing treatment for the arm after stroke; however, knowledge about the content of these treatments is scant. Detailed data are ...

Comprehensive RNA-Seq Profiling to Evaluate the Sheep Mammary Gland Transcriptome in Response to Experimental Mycoplasma agalactiae Infection.

Mycoplasma agalactiae is a worldwide serious pathogen of small ruminants that usually spreads through the mammary route causing acute to subacute mastitis progressing to chronic persistent disease tha...

CCBE1 Mutation causing Sclerosing Cholangitis - Expanding the Spectrum of Lymphedema-Cholestasis Syndrome.

Refractory subacute steatohepatitis after biliopancreatic diversion.

Steatohepatitis development after the biliopancreatic diversion (BPD) procedure for morbid obesity has rarely been reported. We present a case of fatal recurrent steatohepatitis post-PBD despite repea...

Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon.

Animal models are needed to better understand the pathogenic mechanisms of Zika virus (ZIKV) and to evaluate candidate medical countermeasures. Adult mice infected with ZIKV develop a transient viremi...

Stem Cell Recipes of Bone Marrow and Fish: Just What the Stroke Doctors Ordered.

Stem cell therapy for stroke has advanced from the laboratory to the clinic, but remains as an experimental treatment. Two lines of transplant regimens have emerged, namely the "early bird" peripheral...

Subacute Subclinical Brain Infarctions after Transcatheter Aortic Valve Implantation Negatively Impact Cognitive Function in Long-Term Follow-Up.

To date every post-procedural cerebrovascular embolic event (CVE) is dreaded for its potential to accelerate cognitive decline after transcatheter aortic valve implantation (TAVI). This study differen...

Knockout of the Primary Sclerosing Cholangitis-Risk Gene Fut2 Causes Liver Disease in Mice.

The etiopathogenesis of primary sclerosing cholangitis (PSC) is unknown. Genetic variants of fucosyltransferase 2 (FUT2) have been identified in genome-wide association studies as risk factor for PSC....

Management of cholestatic disease in 2017.

Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are the most frequent chronic cholestatic liver diseases and serve as model diseases to discuss the management of cholestasis...

News Articles [50 Associated News Articles listed on BioPortfolio]

MCG Health and MedInsight Formally Launch New Analytics Tool to Increase Healthcare Efficiency

MedInsight® Guideline Analytics offers a granular view into cost measurement of care strategies. Seattle, WA (PRWEB) January 11, 2017 The teams from MCG Health and Milliman MedInsight have colla...

Genesis HealthCare Corp GEN Pharmaceuticals Healthcare Deals and Alliances Profile Prices from USD $250

SummaryGenesis HealthCare Corp Genesis HealthCare is a healthcare company that provides nursing and rehabilitation therapy. The company offers services such as rehabilitation therapy, ventilator care,...

Biotie Therapies AG Pharmaceuticals Healthcare Deals and Alliances Profile Prices from USD $250

SummaryBiotie Therapies AG Biotie is a specialized drug development company. It focuses on the development of products for neurodegenerative and psychiatric disorders such as Parkinson's disease, prim...

Gaucher Disease Type III Pipeline Review, H2 2016 Prices from USD $2000

Gaucher Disease Type III Pipeline Review, H2 2016SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Gaucher Disease Type III Pipeline Review, H2 2016, provide...

Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice

Phenex Wins $100M Milestone from Gilead for Clinical Progress with FXR Agonist

Germany’s Phenex Pharmaceuticals confirmed receipt of a $100M milestone payment from Gilead Sciences, relating to continued clinical development of the synthetic, non-steroidal farnesoid X receptor ...

NAMI Announces Legislative Priorities for 2017

ARLINGTON, Va., Jan. 3, 2017 /PRNewswire-USNewswire/ -- The National Alliance on Mental Illness (NAMI) is pleased to announce its legislative priorities for 2017 as part of our ongoing efforts to ensu...

Researchers Find New Risk Markers for Sclerosing Cholangitis

An international group of researchers have established four new primary sclerosing cholangitis (PSC) markers, one of which points to a possible therapeutic intervention in this currently untreatable l...

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Konstantinos Lazaridis, Carl Anderson and colleagues report results of a genome-wide association study of primary sclerosing cholangitis (PSC). They identify four new susceptibility loci for PSC and q...

Subacute posttraumatic ascending myelopathy: a literature review

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Companies [1 Associated Companies listed on BioPortfolio]

Albert Einstein Healthcare Network

Albert Einstein Healthcare Network is a 1,200 bed integrated delivery network with nearly 7,400 employees serving the communities of North Philadelphia and Montgomery County, PA. ...

Clinical Trials [147 Associated Clinical Trials listed on BioPortfolio]

Natural History of Pain After Shoulder Arthroplasty Conducted With Multimodal Analgesia

This study aims to identify the timeline of pain following total shoulder replacement with the goal of developing data for a subsequent randomized trial. The investigators believe that wit...

The Multitasking Rehabilitation She Enhanced Walking Speed Compared to the Simple Post Stroke Rehabilitation Task (AVC)?

Stroke is the leading cause of severe disability in adults. The first cause of alterations in the quality of life and autonomy in these patients are disorders of walking and the balance. T...

A Single-arm,Phase IIa,Safety and Efficacy Trial of Selected MSCs in the Treatment of Patients With PSC & AiH

MERLIN is an adaptive, single arm, multi-centre, phase IIa multi-disease clinical trial. It is designed to: i) Determine dose safety of ORBCEL-C (selected Mesenchymal stromal cells derive...

Energy Consumption and Cardiorespiratory Load During Robot-Assisted Gait Training in Non-Ambulatory Stroke Patients

The aim of this study will be to investigate the energy consumption, cardiorespiratory load and perceived exertion in non-ambulatory subacute stroke patients during a robot-assisted gait t...

Frailty In Cardiac Surgery Copenhagen Study

Background: Over the past decades we have seen an increase in life expectancy in Denmark. One of the consequences is that the patients who need heart surgery have a higher average age and...

Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury

The investigators will longitudinally measure cerebrovascular reactivity (CVR) by functional near-infrared spectroscopy (fNIRS) in acute (≤3 days from injury), subacute, and chronic phas...

A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis

The purpose of this study is to determine whether curcumin, a drug and naturally-occurring plant compound, is safe and effective in the treatment of primary sclerosing cholangitis (PSC).

ADMSCs for the Treatment of Systemic Sclerosis

Systemic sclerosis (SSc) is a rare autoimmune disease, mainly characterized by cutaneous and visceral fibrosis. Digital ulcer and sclerosing skin are commonly affected on hands, but the tr...

"Remind-to-move" for Promoting Upper Extremity Recovery in Patients With Stroke After Subacute Discharge

This is a multi-centered randomized controlled trial to investigate the effects of "Remind-to-Move" (RTM) using wearable devices at home for promoting upper extremity recovery in stroke pa...

Safety, Tolerability, and Efficacy of GS-9674 in Adults With Primary Sclerosing Cholangitis Without Cirrhosis

The primary objective of this study is to evaluate the safety and tolerability of GS-9674 in adults with primary sclerosing cholangitis (PSC).

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Medical and Biotech [MESH] Definitions

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

The sodium salts of the fatty acids in cod liver oil; an irritant and sclerosing agent used to treat varicose veins and arthritic joints.

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