Subacute Sclerosing Panencephalitis SSPE - Biotech, Pharma and Life Science Channel

02:38 EDT 3rd August 2015 | BioPortfolio

PubMed Articles [200 Associated PubMed Articles listed on BioPortfolio]

182 Acute Putrescine Supplementation With Schwann Cell Transplantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injury.

Schwann cell (SC) transplantation demonstrates significant potential for spinal cord injury (SCI) repair and its use as a therapeutic modality has now progressed to clinical trials for subacute and ch...

Sclerosing Thymoma.

Sclerosing thymoma is an extremely rare entity described mostly in the recent past and, to our knowledge, described in only 14 cases, including one we recently diagnosed at our institution. The pathog...

Acute exacerbation of idiopathic pulmonary fibrosis: shifting the paradigm.

The goal of this review is to summarise the clinical features, management, and prognosis of acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF). AE-IPF has previously been defined based on c...

The emerging pharmacology and function of GPR35 in the nervous system.

G protein-coupled receptor 35 (GPR35) is an orphan G protein-coupled receptor (GPCR) that can be activated by kynurenic acid at high micromolar concentrations. A previously unappreciated mechanism of ...

Invited review: Inflammation during the transition to lactation: New adventures with an old flame.

For dairy cattle, the first several weeks of lactation represent the highest-risk period in their lives after their own neonatal period. Although more than 50% of cows during this period are estimated...

Cognitive-behavioural treatment for subacute and chronic neck pain: A Cochrane Review.

Study Design. Systematic review of randomised controlled trials (RCT).

Evolution of EEG Motor Rhythms after Spinal Cord Injury: A Longitudinal Study.

Spinal cord injury (SCI) does not only produce a lack of sensory and motor function caudal to the level of injury, but it also leads to a progressive brain reorganization. Chronic SCI patients attempt...

Prospective study of bezafibrate for the treatment of primary sclerosing cholangitis.

Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease. Medical treatments must be devised to avoid or postpone liver transplantation in PSC patients. No clinical trial has prospectivel...

Pharmacological inhibition of ASBT changes bile composition and blocks progression of sclerosing cholangitis in mdr2 knockout mice.

Deficiency for mdr2, a canalicular phospholipid floppase, leads to excretion of low phospholipid "toxic" bile causing progressive cholestasis. We hypothesize that pharmacological inhibition of the ile...

Management of benign biliary strictures: current status and perspective.

Benign biliary strictures are common and occur either from hepato-biliary surgery or from diseases including chronic pancreatitis and primary sclerosing cholangitis, among others. The treatment of man...

News Articles [33 Associated News Articles listed on BioPortfolio]

Biotie announces start of tozadenant Phase 3 Study in Parkinson's disease

BIOTIE THERAPIES CORP.     STOCK EXCHANGE RELEASE                 21July 2015 at 09.00 a.m. Biotie announces start of tozadenant Phase 3 Study in Parkinson's disease Bio...

Aceso® Wins the Interactive Customer Experience Industry Excellence Award for Second Straight Year

Aceso wins 2015 ICX Award for Healthcare Industry Aceso, the healthcare industry's premier interactive patient care and digital media solutions provider, announce that for the...

Dr. Jack Kavanaugh Named Chairman of Ireland's Orbsen Therapeutics

LOS ANGELES, June 24, 2015 /PRNewswire/ -- Dr. Jack Kavanaugh, an internationally recognized surgeon and businessman who has spearheaded the commercialization of cellular therapies and emerging b...

Abzena lifted as Gilead speeds up antibody development

Gilead Sciences has said it will push an antibody developed by Abzena straight from phase I into a phase III trial in gastric cancer, providing a boost for the UK company.Gilead said on its first-quar...

Subacute T1-low intensity area reflects neurological prognosis for patients with cervical spinal cord injury without major bone injury

Biotie raises €33.1mm in convertible debt financing

Biotie Therapies Corp. (treatments for alcohol dependence, Parkinson's, cognitive impairment, and primary sclerosing cholangitis) raised €33.1mm ($36.1mm) by selling 220mm convertible promissory not...

Biotie Therapies Corp. (BTH1V) - Financial and Strategic SWOT Analysis Review

Recently added to the BioPortfolio report store, Biotie Therapies Corp. (BTH1V) - Financial and Strategic SWOT Analysis Review is a new report from GlobalData published on 2015-04-05. This 25-page re...

Asterias Biotherapeutics Promotes Edward Wirth, M.D., Ph.D. to Chief Medical Officer

MENLO PARK, Calif., May 7, 2015 /PRNewswire/ -- Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a leading biotechnology company in the emerging field of regenerative medicine, today announced the prom...

El Camino Hospital Performs First In-Human Use of RenovoCath™ Catheter

LOS ALTOS, Calif., May 7, 2015 /PRNewswire/ -- RenovoRx, today, announced the first in-human use of the RenovoCath™ catheter. RenovoRx is a leading developer of innovative solutions fo...

Biotie interim report 1 January - 31 March 2015

BIOTIE THERAPIES CORP.                       Interim Report    6 May, 2015 at 9.00 a.m. Biotie interim report 1 January - 31 March 2015 This is a summary of ...

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Companies [1 Associated Companies listed on BioPortfolio]

Albert Einstein Healthcare Network

Albert Einstein Healthcare Network is a 1,200 bed integrated delivery network with nearly 7,400 employees serving the communities of North Philadelphia and Montgomery County, PA. ...

Clinical Trials [94 Associated Clinical Trials listed on BioPortfolio]

18F-AV-1451 PET Imaging in TBI

This study will evaluate imaging characteristics of 18F-AV-1451 in subjects with subacute traumatic brain injury.

The Effectiveness of Early Botulinum Toxin A Injection for Lower Limbs Spasticity in Subacute Stroke Adults

Botulinum toxin A (BoNT-A) injections are widely used to treat spasticity after stroke. Although this treatment is effective on muscle tone improvement, its effect on gait and ability of d...

Once Versus Twice Daily Electrolyte Monitoring in CHF

Twice daily basic metabolic panel's or labs are common practice at Vanderbilt University Medical Center. However, it is unclear how often the second BMP each day is acted on. the investig...

Low Frequency rTMS With Structured PT Training on Restoring Upper Extremity Function

Stroke is the leading cause of function disability or impairment. Non-promising functional return from upper limb rehabilitation has been reported. With the technology advances, transcran...

Self-regulated Constraint-induced Movement Therapy in Subacute Stroke Patients

Emerging research suggests the use of self-regulation (SR) strategies at improving functional regain in patients with brain injury. SR is proposed to produce an added effect to the effecti...

A Long-Term Extension Study of RP103-MITO-001 to Assess RP103 in Children With Inherited Mitochondrial Disease

Patients (male or female) with either documented genetically confirmed diagnosis of inherited mitochondrial diseases, who are ≥ 2 years old and < 18 years, and meet other specified inclu...

Neuromuscular Electroestimulation and Respiratory Muscle Training in Subacute Stroke

This study, part of a larger research project (The Retornus Study), is aimed to evaluate new strategies to optimize rehabilitation outcomes in dysphagic stroke patients. Main objective is ...

Optical Frequency Domain Imaging (OFDI) for Biliary Stricture Imaging

The goal of this study is to evaluate the potential of comprehensive biliary Optical Frequency Domain Imaging (OFDI) for assessing common bile duct or common hepatic duct strictures, deter...

Primary Sclerosing Cholangitis With Oral Vancomycin by the Study of Its Antimicrobial and Immunomodulating Effects

Determine the benefit of oral vancomycin therapy for Primary Sclerosing Cholangitis.

To Determine the Therapeutic Effect of the Music Glove and Conventional Hand Exercises to Subacute Stroke Patients

The investigators are trying to determine the therapeutic effect of the music glove and conventional hand exercise program to the subacute stroke patients. All participants will be random...

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Medical and Biotech [MESH] Definitions

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

The sodium salts of the fatty acids in cod liver oil; an irritant and sclerosing agent used to treat varicose veins and arthritic joints.


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