Synthesis and Release of Thyroid Hormones - Biotech, Pharma and Life Science Channel
PubMed Articles
Prognostic value of TMPRSS4 expression in patients with breast cancer.
Transmembrane protease, serine 4 (TMPRSS4), is a novel type II transmembrane serine protease that is highly expressed on the cell surface in pancreatic, thyroid, lung, and other cancer tissues, althou...
Differentiated thyroid carcinoma is rare in patients younger than 21 years, especially in children, but it is associated with a greater risk of metastases and recurrence. The aim of our study was to...
MicroRNA (miRNA) expression is deregulated in many types of human cancers, including thyroid cancer. The purpose of this study was to investigate miRNA deregulation in papillary thyroid carcinoma (PTC...
To investigate the effects of a low bisphenol A (BPA) concentration on male reproduction, adult rats were administered a concentration of BPA that was less than the no observable adverse effect level...
The activity of the steroidogenic acute regulatory (StAR) protein is indispensable and rate limiting for high output synthesis of steroid hormones in the adrenal cortex and the gonads, known as the 'c...
Of marsupials and men: "Backdoor" dihydrotestosterone synthesis in male sexual differentiation.
Following development of the fetal bipotential gonad into a testis, male genital differentiation requires testicular androgens. Fetal Leydig cells produce testosterone that is converted to dihydrotest...
The mitochondria are critical for steroidogenesis since the ability of cholesterol to move into mitochondria to be available for cytochrome P450, CYP11A1, determines the efficacy of steroid production...
Mass spectrometry theory and application to adrenal diseases.
The diagnosis and management of adrenal diseases hinge upon accurate determination of hormone concentrations in blood and other body fluids. The advent of immunoassays for various steroid hormones has...
Organelle plasticity and interactions in cholesterol transport and steroid biosynthesis.
Steroid biosynthesis is a multi-step process controlled by pituitary hormones, which, via cAMP-dependent signaling pathways, drive tissue-specific steroid formation. Steroidogenesis begins with the tr...
The production of glucocorticoids and aldosterone in the adrenal cortex is regulated at multiple levels. Biosynthesis of these hormones is initiated when cholesterol, the substrate, enters the inner m...
News Articles
Iodine Deficiency In Pregnant Women May Harm Babies' IQs
Iodine deficiency during pregnancy may have a negative effect on babies' mental development, according to new research published in The Lancet. Iodine is ingested mainly through dairy products and sea...
Targeted Medical Pharma to Present at Marcum MicroCap Conference
Targeted Medical Pharma, Inc. (OTCBB: TRGM), a biotechnology company that develops and distributes prescription medical foods to physicians and pharmacies, today announced...
Dr. Terry Davies is recognized among Castle Connolly's Top Doctors® for New York, NY region in 2013
A New York, NY Board Certified physician specializing in Endocrinology, Diabetes & Metabolism, Dr. Terry Davies, is a Castle Connolly Top Doctor for 2013. NEW YORK, May 22, 2013 /PRNewswire-...
BOSTON, May 22, 2013 /PRNewswire-USNewswire/ -- Castle Connolly Medical Ltd., America's trusted source for identifying Top Doctors, has selected Boston's Pediatric Endocrinology special...
Xtalks presents an interactive live webinar on Thursday May 30, 2013 at 1:00pm EDT on ribosome profiling. Toronto, Canada (PRWEB) May 22, 2013 The ability to sequence genomes has far outstripped appr...
Babak Larian, MD, FACS, and Director of the CENTER for Advanced Head & Neck Surgery in Los Angeles comments on a recent article surrounding Page’s disorder and describes top treatments for the c...
Could a mother's lack of iodine harm her child's IQ?
“Mothers’ diets may harm IQs of two babies in three,” warns The Independent. The newspaper reports on its front page that iodine deficiency is widespread among pregnant women. Iodine is recogni...
DGAP-AFR: Sanochemia Pharmazeutika AG: Release of a Financial report
Sanochemia Pharmazeutika AG / Release of Financial Reports 22.05.2013 09:22 Announcement according to Article 87 Section. 1 BörseG, transmitted by DGAP - a company of EquityStory AG. The issuer is .....
[Comment] Iodine and pregnancy: a call to action
Iodine, a crucial micronutrient, is essential for thyroid hormone production and for normal in-utero neuro-development. During pregnancy, iodine intake must be increased by 50% because of physiologica...
Photo Release -- ECOtality Unveils the Blink(R) HQ Family of Home EV Chargers
SAN FRANCISCO, May 22, 2013 (GLOBE NEWSWIRE) -- ECOtality, Inc. (Nasdaq:ECTY), a leader in clean electric transportation, today introduced Blink HQ, a new family of electric vehicle (EV) charging pro...
Events
An exhibition for producers and suppliers of raw materials and active pharmaceutical ingredients
Companies
GL Rapha have been developing various ranges of pharmaceutical technologies specially focusing on Bio-pharmaceuticals such as recombinant proteins, synthetic peptides, and DDS bio similar based on t...
LifePoint Hospitals, Inc. is a leading hospital company focused on providing quality healthcare services close to home. Through its subsidiaries, LifePoint operates 48 hospital ca...
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Patient Access Solutions, Inc.
Certain statements in this news release may contain forward-looking information within the meaning of Rule 175 under the Securities Act of 1933 and Rule 3b-6 under the Securities...
Zalicus focuses its internal drug development efforts on pain and immuno-inflammatory diseases. Our pipeline for pain includes Exalgo⢠(hydromorphone HCl) extended-release ta...
Doctor Evidence is the leader in the development of digital software technologies and services that find/store/translate and deliver the evidence, from clinical studies, to...
Pacific Biosciences of California, Inc.
Pacific Biosciencesâ mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercializati...
Chisholm Trail Longhorn Beef is a rancher-owned and -operated cooperative that raises longhorns locally on family ranches around Texas. Chisholm Trail longhorns graze in pastures...
Firefly BioWorks, Inc. (Cambridge, MA) is introducing an open platform allowing industrial, academic and clinical scientists to develop and use multiplexed biological assays on st...
Hotze Pharmacy, a part of Hotze Enterprises, is leading a wellness revolution in bioidentical hormone replacement therapy by compounding the finest quality of biologically identic...
Clinical Trials
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standa...
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not rece...
We would like to see if aspirin could block niacin-induced flushing by analyzing blood and urine after taking aspirin. Phase I: 5 days of 81 mg aspirin/placebo followed by 600 mg Niacin,...
This Post Marketing Surveillance study will be performed as an open-label, prospective, non-interventional, uncontrolled study in Human immunodeficit Virus-1 (HIV-1) infected patients. Dat...
Background: The interactive effects of resistance training and dietary protein on hormonal responses in overweight or obese adults are not clear and remain controversial. Investigators tes...
RFA (Radiofrequency Ablation) Versus EA (Ethanol Ablation) for Predominantly Cystic Thyroid Nodules
Ultrasound-guided ethanol ablation is an effective treatment modality for patients with cystic thyroid nodules (cystic portion > 90%); however it is less effective in predominantly cystic...
Mediators of Abnormal Reproductive Function in Obesity (MARO)
The study is seeking to understand how being overweight and obese makes women less fertile. The studies the investigators have done so far indicate that there is a hormone or other substan...
The purpose of this study is to determine that the efficacy of the sustained release (SR) formulation of quetiapine (Seroquel) is not inferior to the immediate release (IR) formulation....
The purpose of this 6-week study is to determine whether treatment with Seroquel® Sustained Release (SR) is more effective than placebo in the treatment of acute schizophrenia. PLEASE NO...
Naltrexone Implants vs. MMT Among Inmates in the Norwegian Correctional Services
The purpose of this clinical trial is to study the efficacy and safety of naltrexone implants as a relapse prevention for opiate addicted inmates about to be released from prison. The expe...
Videos
Thyroid Hormone Production
http://www.handwrittentutorials.com - This tutorial takes a look at the production of thyroid hormones in the Thyroid Gland. This includes the transport of i...
Medical and Biotech [MESH] Definitions
Biomimetics
An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS.
Hypoalbuminemia
A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).
Intercellular Signaling Peptides And Proteins
Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
Peptide Hormones
Hormones synthesized from amino acids. They are distinguished from INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS in that their actions are systemic.
Adp-ribosyl Cyclase
A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.
