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Testicular Torsion - Biotech, Pharma and Life Science Channel

13:49 EDT 18th May 2013 | BioPortfolio

PubMed Articles [ 942 Associated PubMed Articles listed on BioPortfolio]

Assessment of anti-mutagenic, anti-histopathologic and antioxidant capacities of Egyptian bee pollen and propolis extracts.

Bee pollen and propolis are popular, traditional health foods. The objective of the current study was to investigate the anti-mutagenic, anti-histopathologic and antioxidant effects among water extrac...

Development of Cre-loxP technology in zebrafish to study the regulation of fish reproduction.

One cannot seek permission to market transgenic fish mainly because there is no field test or any basic research on technological developments for evaluating their biosafety. Infertility is a necessar...

Comparative Study of Phosphine and N-Heterocyclic Carbene Stabilized Group 13 Adducts L(EH3 ) and L2 (E2 Hn ).

Quantum chemical calculations using density functional theory at the BP86/TZ2P level have been carried out to determine the geometries and stabilities of Group 13 adducts [(PMe3 )(EH3 )] and [(PMe3...

Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model.

Fibroblast growth factor 21 (FGF21) is a novel member identified and was reported to express predominantly in pancreas, liver and adipose tissue, and relatively less in other organs, such as the testi...

Ferulic acid in the treatment of post-diabetes testicular damage: relevance to the down regulation of apoptosis correlates with antioxidant status via modulation of TGF-β1, IL-1β and Akt signalling.

The aim of this study was to investigate the protective effect of ferulic acid at different doses (50 mg kg(-1) alternative day and 50 mg kg(-1) daily) on the streptozotocin (STZ)-induced post...

Silymarin protects from varicocele-induced damages in testis and improves sperm quality: evidence for E2f1 involvement.

This study was designed to evaluate the protective effect of silymarin (SMN) on varicocele-induced damage in testis and its effects on sperm parameters and on antioxidant status. Wistar rats were divi...

Grape juice concentrate protects reproductive parameters of male rats against cadmium-induced damage: a chronic assay.

The aim of the present study was to investigate the effects of long-term grape juice concentrate (GJC) consumption, in two dosages, on the reproductive parameters of cadmium-exposed male rats. The eff...

The cloning of the cdk2 transcript and the localization of its expression during gametogenesis in the freshwater giant prawn, Macrobrachium rosenbergii.

Cyclin-dependent kinases (cdks) are key regulators of the cell cycle. In mammals, cdk2 plays an essential role in the meiosis of spermatocytes and oocytes. To investigate the role of cdk2 kinase durin...

Analysis of the molecular interactions governing the polymorphism of benzamide - a guide to syntheses?

Dispersion-corrected density functional calculations are used to rationalize the subtle differences in the molecular interactions in benzamide crystals. The potential energy of the different polymorph...

Modified fixation free plug technique using a new 3D multilamellar implant for inguinal hernia repair : A retrospective study of a single operator case series.

AIM: Implant fixation, mesh shrinkage and poor quality of tissue ingrowth are unresolved issues in modern hernia repair. Many complications reported in the literature such as bleeding, nerve entrapmen...

News Articles [ 146 Associated News Articles listed on BioPortfolio]

Surveillance Best Follow-Up Strategy Among Men With Stage I Seminoma

A long-term study of men with stage I seminoma, a common form of testicular cancer, suggests that surveillance for cancer recurrence, rather than additional chemotherapy or radiation therapy, is suffi...

Early Stage Testicular Cancer - Surveillance Is Best Follow-Up Strategy

A long-term study of men with stage I seminoma, a common form of testicular cancer, suggests that surveillance for cancer recurrence, rather than additional chemotherapy or radiation therapy, is suffi...

New Research Exploits Women and Commodifies Human Life

SAN RAMON, Calif., May 15, 2013 /PRNewswire-USNewswire/ -- The Center for Bioethics and Culture strongly decries the practice of deriving human embryonic stem cells through cloning because it exploits...

4 New Genetic Risk Factors Identified For Testicular Cancer

A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men to...

Scientists Discover More Genetic Clues to Testicular Cancer

SUNDAY, May 12 (HealthDay News) -- Twelve new genetic regions associated with an increased risk of testicular cancer have been identified by researchers in two studies. One study identified four regi...

New study identifies four genetic variants associated with increased risk of testicular cancer

A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men to...

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

Clare Turnbull and colleagues identify nine new susceptibility loci for testicular germ-cell tumor. The newly identified risk regions include variants near DAZL and PRDM14, genes known to be important...

Meta-analysis identifies four new loci associated with testicular germ cell tumor

Katherine Nathanson and colleagues report four new susceptibility loci for testicular germ cell tumor identified through a meta-analysis of genome-wide association studies with follow-up replication....

Penn Medicine researchers identify four new genetic risk factors for testicular cancer

A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men to...

Twelve new genetic risk variants for testicular cancer

Testicular germ cell tumours (TGCTs) are the most common form of cancer in young adult men, with a peak incidence among those between 25 and 34 years of age. by ecancer reporter Clare Sansom This is...

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Companies [ 1 Associated Companies listed on BioPortfolio]

Ansaris

Ansaris is a division of Locus Pharmaceuticals, a privately held biopharmaceutical company focused on solving today’s small molecule drug discovery challenges, has been the l...

Clinical Trials [ 34 Associated Clinical Trials listed on BioPortfolio]

Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone

The purpose of this study is to test the how the body absorbs and processes new forms of oral testosterone. Information gained during the study may help develop better forms of testosteron...

Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum

This study is being offered to all participants of the ACY-5 study as an optional addition to the male contraceptive study in which they participated. Participation is voluntary. The pur...

Odense Androgen Study: Study of Androgens, Body Composition, and Muscle Function in Danish Men

Objective: - To define a reference-population of healthy young men (20-29 years old). - To establish reference-intervals for: 1. Total, bioavailable and free serum an...

Positron Emission Tomography in Detecting Testicle Cancer

RATIONALE: Imaging procedures such as positron emission tomography may improve the ability to detect the extent of cancer and allow doctors to plan more effective treatment for patients wh...

Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer

RATIONALE: Imatinib mesylate may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. PURPOSE: Phase II trial to study the effectiveness of imatinib mes...

Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell Lung, Breast, Testicular, or Kidney Cancer That is Metastatic or That Cannot Be Treated With Surgery

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may...

Diagnostic Study of Patients With Stage I Testicular Cancer

RATIONALE: Diagnostic procedures may improve a doctor's ability to predict the recurrence of testicular cancer. PURPOSE: Diagnostic trial to detect the risk of recurrent disease in patien...

CT Scans in Treating Patients With Stage I Testicular Cancer After Undergoing Orchiectomy

RATIONALE: Imaging procedures such as CT scans help the doctor in detecting cancer or the recurrence of cancer. Increasing the number of times a CT scan is given may improve the ability to...

Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular Cancer

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It...

Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Ph...

Medical and Biotech [MESH] Definitions

Follicle Stimulating Hormone, Human

A major gonadotropin secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and the LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. The alpha subunit is common in the three human pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.

Hermaphroditism, True

A rare condition of sexual ambiguity in which the individual possesses gonadal tissues of both SEXES, tissues from the OVARY and the TESTIS. There can be a testis on one side and an ovary on the other (lateral), or there may be combined ovarian and testicular tissue (ovotestes) on each side (bilateral). Most common karyotype is 46,XX. Others include 46,XY and 45,X/XY.

Cyclin-dependent Kinase Inhibitor P19

An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN REPEATS. Aberrant expression of this protein has been associated with TESTICULAR CANCER.

Wandering Spleen

A congenital or acquired condition in which the SPLEEN is not in its normal anatomical position but moves about in the ABDOMEN. This is due to laxity or absence of suspensory ligaments which normally provide peritoneal attachments to keep the SPLEEN in a fixed position. Clinical symptoms include ABDOMINAL PAIN, splenic torsion and ISCHEMIA.

Torsion, Mechanical

A twisting deformation of a solid body about an axis. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

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