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Testing - Biotech, Pharma and Life Science Channel

11:38 EDT 19th June 2013 | BioPortfolio

PubMed Articles [ 2733 Associated PubMed Articles listed on BioPortfolio]

Modulation of muscimol state-dependent memory by α2-adrenoceptors of the dorsal hippocampal area.

In the present study, the effects of bilateral intra-dorsal hippocampal (intra-CA1) injections of α2-adrenoceptor agonist and antagonist, on muscimol state-dependent memory were examined in mice. A s...

A powerful and efficient set test for genetic markers that handles confounders.

Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important. In particular, set tests allow for aggreg...

An In Vitro Model of Degenerative Lumbar Spondylolisthesis.

STUDY DESIGN.: A biomechanical human cadaveric study. OBJECTIVE.: To create a biomechanical model of low-grade degenerative lumbar spondylolisthesis (DLS), defined by anterior listhesis, for future te...

What's the Harm? Genetic Counselor Perceptions of Adverse Effects of Genetics Service Provision by Non-Genetics Professionals.

Anecdotal accounts suggest some patients have experienced negative outcomes as a result of receiving genetics services from non-genetics providers, but empirical evidence of these incidents and their...

Utricular function : Correlation of three investigations carried out in routine practice.

BACKGROUND: For vestibular disorders competence in otorhinolaryngology (ENT) is required to diagnose disorders in the complete vestibular system. It seems difficult, however, to evaluate otolithic fun...

An aptasensor for electrochemical detection of tumor necrosis factor in human blood.

Electrochemical aptasensors can detect disease markers such as cytokines to provide point-of-care diagnosis that is low-cost, rapid, specific and sensitive. Herein, we describe the development of an a...

A novel melt stable and high tensile strength biopolymer (polyhydroxyalkanoates) from Bacillus megaterium (MTCC10086) and its characterization.

In the present investigation, we have defined a novel biopolymer from Bacillus megaterium strain with novel melt stability, high tensile strength, and elongation to break properties higher to polyprop...

First-trimester contingent screening for trisomy 21 by biomarkers and maternal blood cell-free DNA testing.

OBJECTIVE: To define risk cut-offs with corresponding detection rates (DR) and false-positive rates (FPR) in screening for trisomy 21 using maternal age and combinations of first-trimester biomarkers...

Implementation of maternal blood cell-free DNA testing in early screening for aneuploidies.

OBJECTIVE: To explore the feasibility of routine maternal blood cell-free (cf) DNA testing in screening for trisomies 21, 18 and 13 at 10 weeks' gestation. METHOD: In this prospective study, women a...

ICD implantation without intraoperative testing does not increase the rate of system modifications and does not impair defibrillation efficacy tested in follow-up.

AIM: The need for implantable cardioverter-defibrillator (ICD) defibrillation testing (DT) and subsequent intraoperative system modifications is discussed controversially. The study's goal was to prov...

News Articles [ 3547 Associated News Articles listed on BioPortfolio]

Ethigen Launches Next Generation (NGS) BRCA Testing With Expanded Hereditary Cancer Panel

Nineteen gene panel provides the most comprehensive hereditary cancer analysis clinically available. Salt Lake City, UT (PRWEB) June 19, 2013 Ethigen announced today the US launch of their expanded B...

Impact Analytical Opens New State-of-the-Art Laboratory Facility

Impact Analytical, a full-service, contract analytical testing laboratory that serves the pharmaceutical, plastics, consumer products, medical device, packaging, automotive...

Perfectus Biomed seals £100k growth funding

A fledging medical testing company has secured £100,000 investment to expand its research team and make other strategic investments.Perfectus Biomed, based at Sci-Tech Daresbury, Cheshire, rec...

Gold Standard Diagnostics’ Next-Generation Lyme Disease Testing Becoming Widely Accepted Amongst Clinical Laboratories

Achieve Accurate, Reproducible Results with FDA Cleared Borrelia burgdorferi B31 Confirmation Blots Gold Standard Diagnostics, Corp. (GSD, www.gsdx.us), a lea...

Aftermath Inc. Biohazard Removal Services Now Using ATP Testing Technology

Detectors will be used to measure biological cleanliness at crime scenes, trauma clean-up. Aurora, IL (PRWEB) June 19, 2013 Aftermath Inc., the country’s leading biohazard remediation company, anno...

RKNet Studios Announced Cognitions Bridge Intelligence Games for Fun, Cognitive Skills Testing and Development for Success in Life

Middletown, NJ (PRWEB) June 19, 2013 Anant Goel, CEO at RKNet Studios stated: "The world is changing and changing rapidly. The first industrial revolution began in Britain in the late 18th c...

Invivoscribe FLT3 Testing Patents Strengthened by Supreme Court Ruling

SAN DIEGO, CA -- (Marketwired) -- 06/19/13 -- In Association of Molecular Pathology v. Myriad, the U.S. Supreme Court struck down BRCA1 and BRCA2 gene patent claims. It is important for the diagnosti...

Self-Testing for HPV

Teaching Kenyan women to collect their own genital specimens to be used in testing for human papillomavirus (HPV)—the primary risk factor for cervical cancer—shows promise in the detection of this...

CML HealthCare Inc. Declares Regular Quarterly Dividend

MISSISSAUGA, ONTARIO -- (Marketwired) -- 06/19/13 -- CML HealthCare Inc. (TSX: CLC) (the "Company" or "CML") today announced the Board of Directors of the Company has declared a regular quarterly ca...

A comparison of the detection of BRCA mutation carriers through the provision of Jewish population-based genetic testing compared with clinic-based genetic testing

Companies [ 166 Associated Companies listed on BioPortfolio]

Pathway Genomics Corporation

Located in San Diego, California, Pathway Genomics owns and operates an onsite federally CLIA (Clinical Laboratory Improvement Amendments) certified and California state-licensed...

PGXL Laboratories, LLC

A privately-owned business located in Louisville, Kentucky, PGXL Laboratories was the first lab in the country CLIA-certified specifically to conduct pharmacogenetic tests. It offers pharmacogenetic t...

NanoLogix, Inc.

NanoLogix is a biotechnology company focused primarily on medical diagnostics. Its products offer accelerated detection and identification of microorganisms present in infectious and non-infectious hu...

NeuroMetrix

NeuroMetrix, Inc. was founded in June 1996 as a spin-off from the Harvard-M.I.T. Division of Health Sciences and Technology. The Company’s mission is to: Create value for our customers by developi...

Aegerion Pharmaceuticals, Inc.

Aegerion Pharmaceuticals is a biopharmaceutical company dedicated to the development and commercialization of innovative, life-altering therapies for patients with debilitating often fatal, rare dis...

DiaTech Oncology

DiaTech Oncology is a privately held clinical pathology laboratory that offers patient-specific chemotherapy testing to help oncologists determine the best cancer treatment plans...

XDx, Inc.

Based in Brisbane, California, XDx is a molecular diagnostics company focused on the discovery, development and commercialization of noninvasive gene expression-based tests for th...

RTI Biologics, Inc.

RTI Biologics Inc. is a leading provider of sterile biologic implants for surgeries around the world with a commitment to advancing science, safety and innovation. RTI prep...

Q'Straint

For over 25 years, Q'Straint has remained focused on one mission: To develop the most innovative solutions that advance the safety and effectiveness of wheelchair passenger travel...

RTI Biologics Inc.

RTI Biologics Inc. was formed when Regeneration Technologies Inc. and Tutogen Medical Inc. merged on Feb. 27, 2008. The company is now a leading provider of sterile biologi...

Clinical Trials [ 829 Associated Clinical Trials listed on BioPortfolio]

Neuropsychological and Behavioral Testing in Young Patients With Cancer

This clinical trial is studying neuropsychological and behavioral testing in young patients with cancer. Collecting information over time from a series of tests may help doctors develop ef...

Comparison of the HyperQ Versus Conventional Electrocardiogram (ECG) to Detect Ischemia

The purpose of the investigation is to verify the efficiency of the HyperQ™ system in detecting exercise induced ischemia, with higher specificity and sensitivity than conventional ECG S...

Marinobufagenin as a Target for DIGIBIND in Preeclampsia

Background: - Preeclampsia is a combination of high blood pressure and other potentially life-threatening symptoms. Preeclampsia occurs in up to 10% of pregnancies and is a...

Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1

This study will evaluate the safety and effectiveness of insulin-like growth factor-1 (IGF-1) to treat patients with X-linked severe combined immunodeficiency (XSCID). Those who have XSCID...

CBT for Social Anxiety Disorder Delivered by School Counselors

This 5-year study addresses the unmet needs of adolescents with social phobia through the testing of a 12-week cognitive-behavioral, school-based group intervention delivered by trained sc...

Exercise and Metformin in Colorectal and Breast Cancer Survivors

Metformin is a medication that is commonly used in the treatment of diabetes. Recently small studies in cancer patients without diabetes suggest that metformin may benefit in lowering ins...

Testing the Helpfulness of 2 Decision Aids for Prostate Cancer

The purpose of this study is to test different methods for communicating information about prostate cancer treatment to men. The investigators are studying how best to present information...

Phase III Randomized Trial of Thalidomide/Dexamethasone vs VAD.

This study compares the response rate, overall response rate and survival of patients with multiple myeloma when randomized to two regimens (thalidomide+Dexamethasone vs. Vincristine+Adria...

The Impact of Cytogam® on Time to Viral Load Reduction in Kidney or Kidney/Pancreas Transplant Recipients With Clinical CMV Disease

This pilot study is to assess whether using CytoGam® in combination with ganciclovir is more effective in reducing the CMV viral load over time, as compared to standard treatment with IV...

Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly

Low cobalamin (vitamin B12) levels are frequent in the elderly. Most often they reflect a mild metabolic abnormality without clinical symptoms (subclinical cobalamin deficiency). It is unc...

Medical and Biotech [MESH] Definitions

Incidental Findings

Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.

Anonymous Testing

Testing in which the source of the specimen or the person being tested is not individually identified.

Leprosy, Paucibacillary

A form of LEPROSY classified by the World Health Organization for the purpose of treatment, based on clinical manifestations and skin smear results. Patients with paucibacillary leprosy have fewer than six skin lesions with no causative agent MYCOBACTERIUM LEPRAE on any slit-skin smear testing. Paucibacillary leprosy encompasses indeterminate, borderline tuberculoid, and tuberculoid leprosy.

Diagnostic Test Approval

The process of gaining approval by a government regulatory agency for DIAGNOSTIC REAGENTS AND TEST KITS. This includes any required preclinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance.

Biological Oxygen Demand Analysis

Testing for the amount of biodegradable organic material in a water sample by measuring the quantity of oxygen consumed by biodegradation of those materials over a specific time period.

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