Thyroid stimulating hormone rDNA - Biotech, Pharma and Life Science Channel
PubMed Articles
INTRODUCTION. MCT8 is a specific transporter for the T4 and T3 thyroid hormones that allows their entry in the brain and other organs. Mutations in MCT8 (Allan-Herndon-Dudley syndrome) lead to a sever...
Macular pathology as a cause of visual impairment?
This article reports a case of a pituitary adenoma as the cause of unilateral visual impairment and concomitant unilateral macular pathology. Pituitary adenomas can be classified into hormone-secretin...
Importance of the nicotinic acetylcholine receptor system in the prefrontal cortex.
The prefrontal cortex (PFC) is responsible for integrating cortical and subcortical inputs to execute essential cognitive functions such as attention, working memory planning and decision-making. The...
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) and triphenyl phosphate (TPP) belong to the group of triester organophosphate flame retardants (OPFRs), which have been used in a wide range of consumer p...
Thermal stressors such as low and high ambient temperature elicit an abundance of neuroendocrine responses including activation of the hypothalamo-pituitary-adrenal (HPA) axis and arginine vasopressin...
Growth hormone (GH), insulin-like growth factor-I (IGF-I), and II (IGF-II) play a key role in the development of preantral to preovulatory follicles in some species. To better understand the role of t...
The copepod Calanus finmarchicus is the most abundant zooplankton species in the North Atlantic. While the life history of this crustacean is well studied, little is known about its peptidergic signal...
Viral infections of the ovary can cause pathological conditions. However, innate antiviral responses in the ovary are poorly understood. In this study, we demonstrate that Toll-like receptor 3 (TLR3),...
We have characterized the response to gonadotropin-releasing hormone 2 (GnRH2) in luteinizing hormone producing cells from gfp-transgenic medaka. Teleosts have separate cells producing the two types o...
The role of ghrelin in energy balance regulation in fish.
Knowledge about the endocrine regulation of energy balance in fish is of interest for basic as well as aquaculture research. Ghrelin is a peptide hormone that was first identified in fish 10years ago...
News Articles
Nurse Practitioners in Frenzy Over "Youth Hormone"
NEW YORK, June 20, 2013 /PRNewswire/ -- While it may seem surprising, the topic of "Youth Hormone" therapy is stealing the show at yet another academic conference. Apparently, the professionals a...
The Firm is investigating Byetta lawsuits on behalf of individuals who developed pancreatitis, pancreatic cancer, or thyroid cancer while using this medication. New York, New York (PRWEB) June 19, 201...
Dr. Bob’s, “The Drugless Doctor,” bestseller "Dr. Bob’s Drugless Guide to Balancing Female Hormones" has been updated with the latest research and indexed for optimized guidance. The...
SAN FRANCISCO , June 19, 2013 /- It may seem like an odd pairing: an oral growth hormone-boosting supplement and possible cure for breast cancer. But these were two of the most talked about topi...
Testosterone Raises Insulin Sensitivity (CME/CE)
SAN FRANCISCO (MedPage Today) -- Giving testosterone to men with type 2 diabetes who are deficient in the hormone improved their insulin sensitivity, researchers reported here.
Breakthrough research of essential molecule reveals important targets in diabetes and obesity
Insulin is the most potent physiological anabolic agent for tissue-building and energy storage, promoting the storage and synthesis of lipids, protein and carbohydrates, and inhibiting their breakdown...
Arem Wellness Announces a Recipe Contest
AremWellness.com is hosting its first ever recipe contest! There will be two lucky winners - each of which will receive an Apple iPad mini. Houston, TX (PRWEB) June 19, 2013 Arem Wellness was develop...
Thyroid Hormone Level May Signal Mortality Risk (CME/CE)
SAN FRANCISCO (MedPage Today) -- Levels of free thyroxine at the higher end of the normal range are associated with all-cause mortality in older men who do not have thyroid disease, researchers found.
L-thyroxine Dampens Renal Function Decline in CKD With SCH
Thyroid hormone replacement therapy might dampen the rate of decline in renal function in patients with stage 2 to 4 chronic kidney disease and subclinical hypothyroidism, researchers report. Me...
Stress hormone could trigger mechanism for the onset of Alzheimer's
A chemical hormone released in the body as a reaction to stress could be a key trigger of the mechanism for the late onset of Alzheimer’s disease.
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Companies
TheAmerican Association of Clinical Endocrinologists (AACE)
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
Dendreon Corporation is a biotechnology company whose mission is to target cancer and transform lives through the discovery, development, commercialization and manufacturing of no...
Cardiac Regeneration Technologies
CRT is a privately held medical device company based out of Woodstock, Georgia. CRT focuses its efforts on the use of pressure pulse technology and therapy on cardiovascular...
Hotze Pharmacy, a part of Hotze Enterprises, is leading a wellness revolution in bioidentical hormone replacement therapy by compounding the finest quality of biologically identic...
The American Association of Clinical Endocrinologists
The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinic...
SANUWAVE Health, Inc. (www.sanuwave.com) is an emerging regenerative medicine company focused on the development and commercialization of non-invasive, biological response activat...
Quidel Corporation serves to enhance the health and well being of people around the globe through the development of rapid diagnostic solutions that can lead to improved patient o...
EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, is a leader in the US biopharmaceutical arena, integrating cutting-edge science with unparalleled patient support...
Progenics Pharmaceuticals, Inc.
Progenics Pharmaceuticals, Inc., of Tarrytown, NY, is a biopharmaceutical company focusing on the development and commercialization of innovative therapeutic products to treat the...
EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, is a leader in the US biopharmaceutical arena, integrating cutting-edge science with unparalleled patient support...
Clinical Trials
S0230 Goserelin in Preventing Ovarian Failure in Women Receiving Chemotherapy for Breast Cancer
RATIONALE: Goserelin blocks hormone production in the ovaries. It is not yet known whether ovarian suppression using goserelin will prevent ovarian failure (early menopause) in women recei...
This randomized phase III trial is studying giving tamoxifen citrate or letrozole together with bevacizumab to see how well it works compared with tamoxifen citrate or letrozole alone in t...
Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children
This is a phase II, open label, active-controlled, randomized safety and dose finding study of different MOD-4023 dose levels compared to daily r-hGH therapy in pre-pubertal growth hormone...
RATIONALE: Aromatase inhibitors, such as letrozole, prevent the formation of estradiol, a female hormone. Giving letrozole together with goserelin, leuprolide, or surgery may be an effecti...
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not rece...
Pamidronate to Treat Osteogenesis Imperfecta in Children
This study will evaluate the effect of pamidronate-a drug that decreases bone resorption (breakdown)-on osteogenesis imperfecta. This is a genetic disorder of collagen, the major protein...
This study will evaluate the safety and effectiveness of insulin-like growth factor-1 (IGF-1) to treat patients with X-linked severe combined immunodeficiency (XSCID). Those who have XSCID...
This study will evaluate whether the drug mifepristone can improve the symptoms of Cushing's syndrome in people with ectopic adrenal corticotrophin hormone (ACTH) secretion. Cushing's synd...
First Human Dose Trial of NNC0195-0092 in Healthy Subjects
This trial is conducted in Europe. The aim of this trial is to assess safety, tolerability, pharmacokinetics (the exposure of the trial drug in the body) and pharmacodynamics (the effect o...
Anabolic and Inflammatory Responses to Short-Term Testosterone Administration in Older Men
Skeletal muscle loss is a common consequence of aging and in some individuals reaches a level that compromises health and quality of life. Age-associated increases in cytokine and inflamm...
Videos
Recombinant DNA ©2004 Demonstratives, Inc.
A 3D animation illustrating the process by which a protein is mass-produced using spliced DNA and bacterial replication. For more animation samples, please v...
Medical and Biotech [MESH] Definitions
Thrombopoiesis
The process of generating thrombocytes (BLOOD PLATELETS) from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via the MEGAKARYOCYTES. The humoral factor with thrombopoiesis-stimulating activity is designated THROMBOPOIETIN.
Luteinization
Formation of CORPUS LUTEUM. This process includes capillary invasion of the ruptured OVARIAN FOLLICLE, hypertrophy of the GRANULOSA CELLS and the THECA CELLS, and the production of PROGESTERONE. Luteinization is regulated by LUTEINIZING HORMONE.
Thyroid Hormone Receptors Alpha
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.
Thyroid Hormone Receptors Beta
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
Luteinizing Hormone, Beta Subunit
The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.
