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Tinnitus - Biotech, Pharma and Life Science Channel

02:51 EDT 19th May 2013 | BioPortfolio

Tinnitus causes people to hear constant sounds in one ear, both ears or in their head. Tinnitus is the medical name for the perception of noise in one ear, both ears or in the head. The noise comes from inside the body rather than an outside source.

People with tinnitus can experience different types of sounds. Most people describe it as a ringing sound, but other sounds may include:

* buzzing
* humming
* whistling
* music

Sometimes, the noise associated with tinnitus beats in time with a person’s pulse. This is known as pulsatile tinnitus.

Tinnitus is often worse at quiet times, such as when you are trying to get to sleep. This is because there is less background noise to distract you from the sounds of tinnitus. The symptom may also be more noticeable when you are tired. Tinnitus is a symptom rather than a condition in itself. The sounds are usually only heard by the person who has tinnitus, although in a few, rare cases they can also be heard by other people. Temporary tinnitus can be caused by a cold, a blow to the head, or prolonged exposure to a loud noise, such as a music concert.
 

Tinnitus is a common condition. A 2007 study carried out by The Royal National Institute for Deaf People (RNID) found that one in seven people in the UK have experienced tinnitus. Long-term tinnitus is much less common, affecting about one in 100 people. Tinnitus can occur at any age but is more common in older people and can sometimes affect young children. Many people learn to live with tinnitus but it can have a significant impact on a person’s everyday life. For example, it can affect concentration and cause sleeping problems and depression.

There is currently no cure for long-term tinnitus. Therefore, the aim of treatments, such as sound therapy, relaxation therapy and cognitive behavioural therapy (CBT), is to help people effectively manage their symptoms.

Source; NHS

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PubMed Articles [ 165 Associated PubMed Articles listed on BioPortfolio]

Establishment of auditory discrimination and detection of tinnitus induced by salicylic acid and intense tone exposure in the rat.

Rats were trained in a two lever food reinforced operant procedure to discriminate a 8000Hz pure tone stimulus from its absence. Responding on one lever was reinforced in the presence of the tone and...

Would an endosteal CI-electrode make sense? Comparison of the auditory nerve excitability from different stimulation sites using ESRT measurements and mathematical models.

Regarding potential endosteal cochlear implant electrodes, the primary goal of this paper is to compare different intra- and extra-cochlear stimulation sites in terms of current strengths needed for s...

Response to the comment on Schecklmann et al.: a call to consider both "negative" and "positive" results in brain research on tinnitus.

Effect of total disc replacement on atypical symptoms associated with cervical spondylosis.

PURPOSE: To determine the efficacy of total disc replacement (TDR) for the treatment of cervical spondylosis associated with atypical symptoms. METHODS: In this retrospective study, patients with myel...

Is tinnitus accompanied by hemifacial spasm in normal-hearing patients also a type of hyperactive neurovascular compression syndrome? a magnetoencephalography study.

BACKGROUND: Traditionally, tinnitus accompanied by hemifacial spasm has been considered a type of hyperactive neurovascular compression syndrome that is similar to hemifacial spasm alone because of th...

Classic and reversal steps stapedotomy performed with CO2 laser: a comparative analysis.

The objective of this paper is to evaluate and compare hearing outcomes, intraoperative and postoperative complications and tinnitus characteristics, with particular regard to the effects of stapes su...

Hyperacusis-associated pathological resting-state brain oscillations in the tinnitus brain: a hyperresponsiveness network with paradoxically inactive auditory cortex.

Although hyperacusis, a hyperresponsiveness to non-noxious auditory stimuli, is a sound-evoked symptom, possible resting-state pathologic oscillations in hyperacusis brain have never been explored. By...

Medically unexplained symptoms and somatisation in ENT.

Background: Somatisation has been described as the perception of a physiological event influenced by emotion. Method: A review of the medical literature was carried out using the following Medical Sub...

Clinical Investigation on the Beneficial Effects of the Chinese Medicinal Herb Gushen Pian on Sensorineural Deafness and Tinnitus.

The objective is to study the therapeutic effects of Gushen Pian on sensorineural deafness according to the Phase II clinical trial protocol, as approved for novel traditional Chinese medicines by Min...

Incidence of Adverse Events Among Healthcare Workers Following H1N1 Mass Immunization in Ghana : A Prospective Study.

BACKGROUND: Cases of the A(H1N1) 2009 influenza were first recorded in Ghana in July 2009. In June 2010 when prioritized vaccination against the novel A(H1N1) 2009 influenza virus started in the count...

News Articles [ 103 Associated News Articles listed on BioPortfolio]

Sound Relief Hearing Center Announces Expanded Tinnitus Treatment Offerings in Sync with National Tinnitus Awareness Week

Highlands Ranch, CO, May 17, 2013 --(PR.com)-- In sync with National Tinnitus Awareness Week May 19 – 25, the Sound Relief Hearing Center today announced the expansion of its tinnitus treatment...

Imaginears, Inc. Launches Weekly Blog Covering Hearing Loss and Hearing Aids in Medford OR

A new weekly blog on the website of Imaginears, Inc. in Medford OR will provide a way for the audiologists to share advice, research and innovations related to hearing aids and hearing loss. Medford,...

SoundCure Supports Tinnitus Awareness Week, Marks One-Year Anniversary

SAN JOSE, CA -- (Marketwired) -- 05/16/13 -- As Tinnitus Awareness Week commences, (May 19-25), SoundCure®, along with the American Tinnitus Association and tinnitus sufferers will draw attention to...

Miami Hearing Aid Leader Launches Weekly Blog to Educate Consumers about Hearing Loss and Hearing Aids

Progressive Hearing in Miami has added a weekly blog to their website where the audiologists will share hearing healthcare advice and tips. Miami,FL (PRWEB) May 15, 2013 Progressive Hearing recently...

The Key of Life

Hearing aid designed for hearing loss and tinnitus gives a music aficionado his life back.

[Auris Medical] advances tinnitus drug therapy development with funds from CHF47.1mm Series C round

[Auris Medical AG] (developing drug therapies for inner ear disorders) raised CHF47.1mm ($50.3mm) through its Series C round. Sofinnova Ventures and Sofinnova Partners participated, and both gain repr...

[Auris Medical] brings in CHF11mm through Series B round

[Auris Medical AG] (developing therapeutics for tinnitus and hearing loss) raised CHF11mm ($9.95mm) through its Series B round. AGF Private Equity participated, along with ZKB Pharma Vision Fund and L...

Sound Relief Hearing Center Announces Grand Opening of New Office in Centennial

Centennial, CO, May 02, 2013 --(PR.com)-- Sound Relief Hearing Center today announced the grand opening of a second office in Centennial, Colo. complementing its other south Metro Denver practice loc...

Auris selects Medidata Clinical Cloud for tinnitus research

Swiss pharmaceutical firm Auris Medical has chosen Medidata Solutions' cloud platform for the development of technologies related to inner ear disorders, to support the company's pivotal clinical tria...

Pioneering Swiss Pharma Auris Medical Selects Medidata Clinical Cloud to Support Novel Tinnitus Research

Medidata Solutions’ (NASDAQ: MDSO) cloud platform has been selected by Auris Medical, a Swiss pharmaceutical firm focused on developing novel therapies for inner ear diso...

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Companies [ 3 Associated Companies listed on BioPortfolio]

Starkey Hearing Technologies

The Xino™ Tinnitus device, sold under the Starkey brand, uses advanced technology to create a customizable and comforting sound stimulus that can be fine-tuned and personaliz...

MicroTransponder, Inc.

MicroTransponder (www.microtransponder.com) is developing a wireless neurostimulation system for the treatment of chronic pain and several other neurological indications. The mini...

SoundCure

SoundCure is focused on developing and commercializing a novel acoustic therapy for the treatment of tinnitus (ringing in the ear). The company will partner with audiologists, MDÃ...

Clinical Trials [ 42 Associated Clinical Trials listed on BioPortfolio]

Early Diagnosis of Steroid-Responsive & No-Responsive Hearing Loss

Tinnitus is a prevalent issue for veterans who are proportionally more hearing-impaired than the civilian population. This study will be conducted as three concurrent projects designed to...

Safety and Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus

Tinnitus, i.e., the perception of sounds or noise in the absence of auditory stimuli, is a frequent and often severely disabling symptom of different disorders of the auditory system. Ther...

Psychophysiological Treatment of Chronic Tinnitus

The study aims to develop and to evaluate a psychophysiological intervention for distressing chronic tinnitus. Therefore 100 people suffering from chronic tinnitus are randomly assigned to...

Brain Imaging of Tinnitus

This study will use magnetic resonance imaging (MRI) to compare brain function in three groups of people: hearing-impaired people with tinnitus; hearing-impaired people without tinnitus; a...

Using PET-CT to Target and Validate Low-Frequency TMS as Treatment for Tinnitus

One out of every five people experience tinnitus (a buzzing, ringing, or roaring sound in the ear) ranging from mild to severe impairment. To date there is no effective therapy that seems...

The Effect of Tinnitus Retraining Therapy on Subjective and Objective Measures of Chronic Tinnitus

The objective of this study is to examine the efficacy of tinnitus retraining therapy (TRT) as a treatment of chronic tinnitus in people with limited hearing loss. The study design is pro...

Cost-effectiveness of Multidisciplinary Management of Tinnitus

Background: Tinnitus is a common chronic health condition that affects 10% to 20% of the general population. Among severe sufferers it causes disability in various areas. As a result of th...

Customized Acoustic Stimulation for Long Term Medical Benefit for the Relief of Tinnitus and Hyperacusis

Neuromonics TInnitus Treatment CALM study is a multi site study of 100 adult subjects with clinically significant disturbing tinnitus to evaluate outcome measures using the FDA cleared Neu...

Cognitive Behavioral Therapy (CBT) for Tinnitus

This study examines how useful it is to teach veterans coping skills for dealing with tinnitus, also called ringing in the ears. A psychological intervention, cognitive-behavioral therapy...

Vardenafil in Tinnitus

There is incidental evidence (casuistic findings) that the treatment with vardenafil of male patients suffering from erectile dysfunction and comorbid tinnitus experienced an improvement...

Medical and Biotech [MESH] Definitions

Glomus Tympanicum Tumor

A rare PARAGANGLIOMA involving the GLOMUS TYMPANICUM, a collection of chemoreceptor tissue adjacent to the TYMPANIC CAVITY. It can cause TINNITUS and conductive hearing loss (HEARING LOSS, CONDUCTIVE).

Pseudotumor Cerebri

A condition marked by raised intracranial pressure and characterized clinically by HEADACHES; NAUSEA; PAPILLEDEMA, peripheral constriction of the visual fields, transient visual obscurations, and pulsatile TINNITUS. OBESITY is frequently associated with this condition, which primarily affects women between 20 and 44 years of age. Chronic PAPILLEDEMA may lead to optic nerve injury (see OPTIC NERVE DISEASES) and visual loss (see BLINDNESS).

Tinnitus

A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.

Herpes Zoster Oticus

A syndrome characterized by facial palsy in association with a herpetic eruption of the external auditory meatus. This may occasionally be associated with tinnitus, vertigo, deafness, severe otalgia, and inflammation of the pinna. The condition is caused by reactivation of a latent HERPESVIRUS 3, HUMAN infection which causes inflammation of the facial and vestibular nerves, and may occasionally involve additional cranial nerves. (From Adams et al., Principles of Neurology, 6th ed, p757)

Endolymphatic Hydrops

An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.

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