The Top 100 Drugs - Biotech, Pharma and Life Science Channel
The pharmaceutical industry is massive, both in range of products and in financial values.
These are the top 200 drugs (ranked in descending order according to total sales in 20010, $), and the companies that make them. To find out more about the Companies, visit the Corporate pages of BioPortfolio.
Rank Drug Current Manufacturer Total Sales ($000) % change 2009
1 Nexium AstraZeneca Pharmaceuticals 5,276,153 4.90%
2 Lipitor Pfizer Inc 5,272,576 -2.30%
3 Plavix Bristol-Myers Squibb Company 4,675,483 10.20%
4 Advair Diskus GlaxoSmithKline 3,655,206 -1.00%
5 OxyContin Purdue Pharma LP 3,554,751 13.10%
6 Abilify Bristol-Myers Squibb Company 3,514,265 12.70%
7 Singulair Merck & Co., Inc. 3,324,909 8.90%
8 Seroquel AstraZeneca Pharmaceuticals 3,222,055 2.40%
9 Crestor AstraZeneca Pharmaceuticals 2,922,687 27.00%
10 Cymbalta Eli Lilly and Company 2,638,536 7.60%
11 Actos Takeda Pharmaceuticals North America, Inc 2,631,930 4.20%
12 Lexapro Forest Pharmaceuticals, Inc 2,483,391 4.60%
13 Zyprexa Eli Lilly and Company 2,036,092 7.70%
14 Spiriva Boehringer Ingelheim Pharmaceuticals, Inc 1,593,593 19.30%
15 Lantus Sanofi-Aventis 1,525,697 0.30%
16 Aricept Eisai Corporation 1,522,517 13.30%
17 Lyrica Pfizer Inc 1,478,158 -0.10%
18 Diovan Novartis Corporation 1,443,539 7.00%
19 Effexor XR Wyeth 1,431,042 -40.10%
20 Concerta Ortho-McNeil-Janssen Pharmaceuticals, Inc. 1,407,962 16.90%
21 Levaquin Janssen Pharmaceuticals, Inc 1,355,350 -0.60%
22 Celebrex Pfizer Inc 1,349,833 -6.90%
23 Diovan HCT Novartis Corporation 1,314,507 3.70%
24 Januvia Merck & Co., Inc. 1,294,408 13.00%
25 Suboxone Reckitt Benckiser Pharmaceuticals Inc. 1,164,872 26.60%
26 NovoLog Novo Nordisk Inc. 1,101,447 20.60%
27 Viagra Pfizer Inc 1,028,769 5.50%
28 Atripla Gilead Sciences, Inc. 1,028,753 -6.50%
29 Tricor Abbott Laboratories 1,015,682 -17.20%
30 Provigil Cephalon, Inc. 999,975 6.70%
31 Zetia Schering-Plough 985,823 -4.30%
32 Geodon oral Pfizer Inc 959,057 8.70%
33 Vytorin Merck & Co., Inc. 953,625 -16.30%
34 Ambien CR Sanofi-Aventis 951,108 -2.50%
35 Lunesta Sepracor Inc. (renamed Sunovion Pharmaceuticals Inc) 948,621 17.60%
36 Lidoderm Endo Pharmaceuticals 934,418 -1.10%
37 Lantus SoloSTAR Sanofi-Aventis 933,589 50.50%
38 Vyvanse Shire US Inc 931,421 40.90%
39 Aciphex Eisai Corporation 915,796 -8.80%
40 Nasonex Schering-Plough 886,446 -1.90%
41 Lovenox Sanofi-Aventis 867,240 -20.40%
42 Adderall XR Shire US Inc 837,448 -27.00%
43 ProAir HFA Teva Pharmaceuticals 818,903 -12.60%
44 Truvada Gilead Sciences, Inc. 813,944 -8.50%
45 Niaspan Abbott Laboratories 793,882 11.00%
46 Humalog Eli Lilly and Company 783,294 3.20%
47 Cialis Eli Lilly and Company 756,576 15.90%
48 Namenda Forest Pharmaceuticals, Inc 744,296 10.90%
49 Symbicort AstraZeneca Pharmaceuticals 707,468 47.40%
50 Flovent HFA GlaxoSmithKline 704,631 13.20%
51 Seroquel XR AstraZeneca Pharmaceuticals 695,560 92.10%
52 Combivent Boehringer Ingelheim Pharmaceuticals, Inc 693,068 14.30%
53 Lovaza GlaxoSmithKline 682,384 15.50%
54 Solodyn Medicis Pharmaceutical Corporation 673,427 40.70%
55 Detrol LA Pfizer Inc 620,231 -13.60%
56 AndroGel Abbott Laboratories 593,780 10.10%
57 Benicar Daiichi Sankyo 567,636 10.00%
58 Levemir Novo Nordisk Inc. 567,341 41.10%
59 Enbrel Amgen Inc. 546,814 -15.80%
60 Valtrex GlaxoSmithKline 533,961 -69.90%
61 Benicar HCT Daiichi Sankyo 526,177 -3.10%
62 Gleevec Novartis Corporation 517,967 -3.70%
63 Humira Pen Abbott Laboratories 514,735 10.10%
64 Synthroid Abbott Laboratories 506,859 2.50%
65 Xalatan Pfizer Inc 502,227 9.10%
66 Premarin tabs Wyeth 497,757 -6.50%
67 Strattera Eli Lilly and Company 496,960 -3.90%
68 Ventolin HFA GlaxoSmithKline 496,659 65.40%
69 Flomax Boehringer Ingelheim Pharmaceuticals, Inc 486,106 -68.90%
70 Loestrin 24 Fe Warner Chilcott 483,754 82.30%
71 Protonix Wyeth 481,429 3.50%
72 Boniva Genentech, Inc 480,470 -5.30%
73 Restasis Allergan, Inc 480,414 19.00%
74 Femara Novartis Corporation 477,256 12.70%
75 Enbrel Sureclick Amgen Inc. 474,602 2.60%
76 NovoLog Mix 70/30 Novo Nordisk Inc. 470,786 16.80%
77 Evista Eli Lilly and Company 469,013 0.30%
78 Byetta Amylin Pharmaceuticals, Inc. 459,454 -17.80%
79 Janumet Merck & Co., Inc. 459,068 22.70%
80 Asacol Procter & Gamble 450,645 -8.30%
81 Avodart GlaxoSmithKline 441,486 5.50%
82 Vesicare Astellas Pharma US 440,862 15.30%
83 Trilipix Abbott Laboratories 428,978 104.50%
84 Copaxone Sanofi-Aventis 421,758 1.30%
85 Focalin XR Novartis Corporation 416,245 18.60%
86 Reyataz Bristol-Myers Squibb Company 412,293 -20.90%
87 Pristiq Wyeth 411,715 58.40%
88 Arimidex AstraZeneca Pharmaceuticals 403,891 -37.50%
89 Chantix Pfizer Inc 394,944 -14.30%
90 Sensipar Amgen Inc. 382,232 -0.50%
91 Avapro Bristol-Myers Squibb Company 369,596 -6.20%
92 Opana ER Endo Pharmaceuticals 366,417 52.50%
93 Yaz Bayer Healthcare Pharmaceuticals 361,958 -49.10%
94 Doryx Pfizer Inc 361,662 35.70%
95 Actoplus Met Takeda Pharmaceuticals North America, Inc 359,790 4.70%
96 Humira Abbott Laboratories 358,012 -12.50%
97 Avelox Bayer Healthcare Pharmaceuticals 353,130 -8.40%
98 NuvaRing Merck & Co., Inc. 349,014 11.00%
99 Renvela Genzyme Corporation 333,987 111.50%
100 Ortho Tri-Cyclen Lo Ortho-McNeil-Janssen Pharmaceuticals, Inc. 331,730 33.90%
101 Lamictal GlaxoSmithKline 326,331 -35.20%
102 Avalide Bristol-Myers Squibb Company 324,571 -6.40%
103 Xopenex Sepracor Inc. (renamed Sunovion Pharmaceuticals Inc) 316,162 -13.00%
104 Actonel Procter & Gamble 313,904 -29.00%
105 Dexilant/Kapidex 313,386 254.80%
106 Lotrel Novartis Corporation 306,010 -6.80%
107 Invega Janssen Pharmaceuticals, Inc 304,182 5.10%
108 Welchol Daiichi Sankyo 303,392 19.70%
109 Avonex Biogen Idec 303,147 0.20%
110 Topamax Janssen Pharmaceuticals, Inc 287,186 -70.50%
111 Norvir Abbott Laboratories 287,102 -10.00%
112 Entocort EC AstraZeneca Pharmaceuticals 282,547 38.60%
113 Aggrenox Boehringer Ingelheim Pharmaceuticals, Inc 277,144 6.50%
114 Travatan Z Alcon Laboratories, Inc. 273,598 44.10%
115 Isentress Merck & Co., Inc. 272,132 -9.80%
116 Avandia GlaxoSmithKline 269,213 -33.80%
117 Prevacid SoluTab Takeda Pharmaceuticals North America, Inc 268,284 -1.40%
118 Exforge Novartis Corporation 267,771 16.60%
119 Cozaar Merck & Co., Inc. 267,081 -62.40%
120 Lumigan Allergan, Inc 267,047 7.00%
121 Caduet Pfizer Inc 266,967 -18.60%
122 Actonel 150 Procter & Gamble 264,858 26.20%
123 Risperdal Consta Janssen Pharmaceuticals, Inc 262,054 -8.20%
124 Prograf Astellas Pharma US 260,885 -56.20%
125 Ciprodex otic Alcon Laboratories, Inc. 254,888 13.80%
126 Vigamox Alcon Laboratories, Inc. 252,864 11.30%
127 Kadian Actavis 251,858 -0.80%
128 Coreg CR GlaxoSmithKline 251,440 -1.60%
129 Levitra Bayer Healthcare Pharmaceuticals 242,446 -5.90%
130 Maxalt Merck & Co., Inc. 242,237 0.50%
131 Keppra UCB Inc. 241,737 -33.00%
132 Prevacid Takeda Pharmaceuticals North America, Inc 241,374 -90.60%
133 Micardis Boehringer Ingelheim Pharmaceuticals, Inc 238,335 23.90%
134 Bystolic Forest Pharmaceuticals, Inc 231,449 72.20%
135 Prezista Centocor Ortho Biotech, Inc 230,406 13.80%
136 Exelon Patch Novartis Corporation 229,601 38.20%
137 Nuvigil Cephalon, Inc. 223,885 239.60%
138 Zyvox Pfizer Inc 222,554 -7.50%
139 Lialda Shire US Inc 222,201 29.30%
140 Epzicom GlaxoSmithKline 221,406 -17.00%
141 Enablex Warner Chilcott 220,478 11.00%
142 Forteo Eli Lilly and Company 219,387 -25.10%
143 Viread Gilead Sciences, Inc. 216,264 -6.20%
144 Kaletra Abbott Laboratories 212,723 -32.90%
145 Micardis HCT Abbott Laboratories 211,575 10.40%
146 Maxalt MLT Merck & Co., Inc. 211,230 -1.10%
147 Humalog Mix 75/25 Pen Eli Lilly and Company 211,021 -6.90%
148 Xeloda Roche Pharmaceuticals 209,499 -11.70%
149 Asmanex Schering-Plough 208,839 3.80%
150 Hyzaar Merck & Co., Inc. 207,471 -62.30%
151 Fentora Cephalon, Inc. 207,376 11.20%
152 Pulmicort Respules AstraZeneca Pharmaceuticals 205,218 -68.00%
153 Ranexa Gilead Sciences, Inc. 200,622 41.50%
154 RenaGel Genzyme Corporation 199,275 -48.20%
155 Prempro Wyeth 198,132 22.20%
156 Relpax Pfizer Inc 197,341 -3.40%
157 Patanol Alcon Laboratories, Inc. 196,500 2.60%
158 Amitiza Takeda Pharmaceuticals North America, Inc 195,132 1.40%
159 Duragesic 194,599 -14.50%
160 Vancocin HCl Eli Lilly and Company 192,066 23.40%
161 Nasacort AQ Sanofi-Aventis 192,035 -19.00%
162 Proventil HFA Schering-Plough 191,839 -26.50%
163 Advair HFA GlaxoSmithKline 191,245 26.40%
164 Valcyte Roche Pharmaceuticals 191,160 -0.90%
165 Wellbutrin XL Valeant Pharmaceuticals International 189,026 -21.20%
166 Oracea Galderma Laboratories 187,182 67.90%
167 Vivelle-DOT Novartis Corporation 185,860 12.40%
168 Uroxatral Sanofi-Aventis 185,624 6.20%
169 Zovirax topical GlaxoSmithKline 184,377 2.60%
170 Epipen 182,785 20.80%
171 Creon Solvay Pharmaceuticals, Inc. 181,303 358.60%
172 Azor 179,647 33.00%
173 Pentasa Sanofi-Aventis 178,068 4.50%
174 Procrit Centocor Ortho Biotech, Inc 174,622 -25.90%
175 Pataday Alcon Laboratories, Inc. 173,553 25.50%
176 Differin Galderma Laboratories 171,454 -24.80%
177 Premarin vaginal Wyeth 170,860 3.50%
178 Zyprexa Zydis Eli Lilly and Company 169,714 6.70%
179 Tussionex Sanofi-Aventis 169,611 -29.80%
180 Victoza Novo Nordisk Inc. 168,943 0.00%
181 Humalog KwikPen Eli Lilly and Company 168,270 79.60%
182 Arixtra GlaxoSmithKline 165,530 19.90%
183 Qvar Janssen Pharmaceuticals, Inc 163,697 41.10%
184 Combivir GlaxoSmithKline 163,406 -27.80%
185 Testim 163,015 12.20%
186 Tarceva Genentech, Inc 160,591 -38.20%
187 Xyzal Sanofi-Aventis 160,237 -15.60%
188 Elmiron Ortho-McNeil-Janssen Pharmaceuticals, Inc. 158,274 4.30%
189 Propecia Merck & Co., Inc. 157,892 -5.70%
190 CellCept Roche Pharmaceuticals 157,743 -68.30%
191 Skelaxin Elan Corporation 156,372 -67.70%
192 Betaseron Bayer Healthcare Pharmaceuticals 155,952 -6.80%
193 Temodar Schering-Plough 154,466 -14.90%
194 Flector Actavis 153,814 0.20%
195 Pegasys Genentech, Inc 153,101 -8.40%
196 Prandin Novo Nordisk Inc. 151,678 -5.90%
197 Veramyst GlaxoSmithKline 150,582 -7.80%
198 Intuniv Shire US Inc 150,346 NA
199 Clobex Galderma Laboratories 150,230 20.60%
200 Humulin N Eli Lilly and Company 149,945 4.40%
Source: Verispan, VONA
Source; http://www.drugs.com/top200.html
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Medical and Biotech [MESH] Definitions
Cinnamomum Aromaticum
A plant species of the genus CINNAMOMUM that contains CINNAMATES and has been used in traditional Chinese medicine (DRUGS, CHINESE HERBAL).
Epimedium
A plant genus of the family BERBERIDACEAE which is used in DRUGS, CHINESE HERBAL. Members contain flavonol glycosides including epimedins, icariin and noricariin.
Cuscuta
A plant genus of the family Cuscutaceae. It is a threadlike climbing parasitic plant that is used in DRUGS, CHINESE HERBAL.
Histamine H1 Antagonists, Non-sedating
A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.
Herb-drug Interactions
The effect of herbs, other PLANTS, or PLANT EXTRACTS on the activity, metabolism, or toxicity of drugs.
