Transdermal and Intravaginal Steroid Contraceptives - Biotech, Pharma and Life Science Channel
PubMed Articles
INTRODUCTION: Nonunion of femoral neck fractures frequently occurs in elderly patients. In patients with rheumatoid arthritis, reoperation rates after internal fixation of a displaced femoral neck fra...
PURPOSE: The purpose of this survey was to quantify oral contraceptive pill (OCP) use and to analyze attitudes and knowledge about the pill in a sample of female medical students. METHODS: A cross-sec...
To determine whether immediate post-operative brachytherapy can be safely applied to newly diagnosed glioblastomas to retard tumor progression prior to initiation of external beam radiation therapy (E...
Within the combined DFG research project "Sulfated Steroids in Reproduction" an analytical method was needed for determining sulfated and unconjugated steroids with highest specificity out of differen...
Incidence of anabolic steroid counterfeiting in Brazil.
This retrospective study reports data obtained from the National Institute of Criminalistics of the Brazilian Federal Police Department (DPF) on 3676 anabolic products seized between 2006 and 2011. An...
Co-encapsulation of drugs directed at commonly associated diseases provides a convenient means for administration, especially if transdermally delivered. In this work, a comprehensive study for the co...
Polycystic ovary syndrome (PCOS) is a heterogeneous disease with a strong genetic origin, but the specific determinants are still unknown. The aim of this study was to investigate the association betw...
PURPOSE: To elucidate the effectiveness of steroid administration and transcorneal electrical stimulation (TES) on anatomic changes and visual function in a rodent model of nonarteritic ischemic optic...
Mounting magnetic resonance imaging (MRI) research is characterising the neurobiological trajectories of healthy human brain development. In parallel, studies increasingly acknowledge the relevance of...
Circulating endothelial progenitor cells (EPCs) are bone marrow-derived cells required for endothelial repair. A low EPC number can be considered as an independent predictor of endothelial dysfunction...
News Articles
Neupro reduces PLMS and total NSBP elevations in patients with RLS, study finds
UCB today announced data from a double-blind, placebo-controlled study that found that Neupro (Rotigotine Transdermal System) reduced total nocturnal systolic blood pressure elevations associated with...
New study shows UCB's Neupro reduces NSBP in RLS patient
Leading Belgian drugmaker UCB (Euronext Brussels: UCB) today (May 17) announced data from a double-blind, placebo-controlled study that found that Neupro (rotigotine transdermal system) reduced total...
Evestra Pharmaceuticals Inc. aims to leverage its managers’ and advisors’ understanding of steroid drugs, then amplify that with expertise in medicinal chemistry, polymer science, and drug deliver...
Liberty University's Challenge To The Health Law Has A Day In Appellate Court
Mathew Staver, the university's lawyer, told the 4th U.S. Circuit Court of Appeals panel that Liberty would face millions of dollars in penalties if it refuses to provide employee health insurance tha...
Echo Therapeutics to Unveil Symphony® CGM System in Webcast
PHILADELPHIA, May 16, 2013 /PRNewswire/ -- Echo Therapeutics, Inc. (Nasdaq: ECTE), a company developing its needle-free Symphony® CGM System as a non-invasive, wireless, transdermal continuous gl...
J&J/Janssen win FDA nod for Simponi in ulcerative colitis
Johnson & Johnson unit Janssen Biotech gained the US FDA's approval to market Simponi (golimumab) as a treatment for with moderate to severe ulcerative colitis (UC) resistant to prior treatment or...
Bayer to pay $24 million to settle Yasmin/Yaz Lawsuits: Now, AttorneyOne Can Provide Advice
As Thomson Reuters published on March 20, 2013 Bayer agreed to settle lawsuits alleging gallbladder injuries from Yasmin and Yaz contraceptives. In light of this news, AttorneyOne, a recognized author...
Contraceptives and the Law A View From a Catholic Medical Institution Contraceptives and the Law
Zosano Pharma, Inc. Appoints Nandan Oza as Chief Operations Officer
FREMONT, Calif., May 14, 2013 /PRNewswire/ -- Zosano Pharma, Inc., a privately held pharmaceutical company developing products based on its novel transdermal delivery technology, announced today...
TAIPEI, Taiwan, May 14, 2013 /PRNewswire/ -- TWi Pharmaceuticals, Inc. (Taiwan OTC: 4180) today announced that it has received tentative approval for its Abbreviated New Drug Application (ANDA) for Gu...
Events
None
Companies
Neurowave Medical Technologies
Neurowave Medical TechnologiesTM (NMT) is a rapidly growing, privately held Chicago-based medical device company that develops and manufactures transdermal neuromodulation devices...
Alliqua, Inc. (âAlliquaâ), formerly HepaLife Technologies, Inc., (OTCBB: HPLF) (FWB: HL1), is an advanced biomedical products company focused on the development and manu...
BioChemics is a pharmaceutical company that has developed a portfolio of novel topical and transdermal drug delivery systems that allow a substantial amount of drugs that were pre...
BioSante Pharmaceuticals, Inc. and ANI Pharmaceuticals, Inc.
BioSanteâs corporate strategy is to develop high value medically-needed pharmaceutical products and to implement strategic alternatives with respect to its products and its c...
BioSante Pharmaceuticals, Inc.
BioSante is a specialty pharmaceutical company focused on developing products for female sexual health and oncology. BioSanteâs lead products include LibiGel® (transdermal...
The Taylor Hooton Foundation was founded in 2004 after Don Hootonâs son Taylor, an aspiring baseball player, took his own life because of steroid use. The Foundation seeks to...
Antares Pharma, Inc. and Population Council
Antares Pharma focuses on self-injection delivery technologies and topical gel-based pharmaceutical products. The Companyâs subcutaneous injection technology platforms includ...
Galdermaâs ambition is to be recognized as the most competent and successful innovation-based company focused exclusively on meeting the needs of dermatology patients and phy...
Established in 2000, TransPharma Medical Ltd. is a specialty pharmaceutical company focused on the development and commercialization of drug products utilizing its proprietary act...
Founded in 1990, Labtec has quickly become one of the leading drug delivery development companies in the transdermal and topical patch arena, later also leading the market with fa...
Clinical Trials
The investigators hypothesize that a calcineurin inhibitor-free, steroid-free, co-stimulatory blockade-based immunosuppressive regimen, in combination with a GLP-1 agonist, will reduce the...
Mesenchymal Stromal Cells (MSCs) for the Treatment of Graft Versus Host Disease (GVHD)
This is a bicentric, prospective, non randomized study. Pediatric and adult patients will be treated. Rationale: MSC have shown promising effects by reversal of severe therapy-resistant a...
Islet Transplantation in Type 1 Diabetic Patients
Our hypothesis is that a successful clinical islet transplant program can be established at the University of Wisconsin using a steroid -free, sirolimus- and low dose tacrolimus - based im...
Oral Contraceptives in the Metabolic Syndrome
Oral contraceptives (OCs) are the most widely used method of reversible birth control. However, the long-term cardiovascular safety of the widely used low-dose OCs (ethinyl-estradiol < 50...
Prospective, Randomized, Multi-center Clinical Study of Plasma Disc Decompression
The goal of this post-marketing surveillance study is to compare two procedures which are used to treat patients who require a disc decompression procedure. These procedures are: 1) plasma...
Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans
African Americans receiving a kidney transplant are considered at high risk for early rejection of their transplanted kidney and require more immunosuppression to maintain their kidney tra...
Use of Campath for Induction and Maintenance Therapy in Pancreas After Kidney Transplantation
This is a single center, prospective, open-label, randomized trial at the University of Minnesota Medical Center,Fairview. Primary objectives are to determine if rejection episodes and lo...
The Role of Insulin Resistance in PCOS
Polycystic ovary syndrome (PCOS) phenotype can be structured into three components: anovulation, hyperandrogenism and the metabolic syndrome (of which hyperinsulinemia, secondary to insuli...
Neoadjuvant Estradiol or Androgen Deprivation in Clinically Localized Prostate Cancer
Prostate cancer is the most commonly diagnosed cancer among males in the U.S. More than 220,000 men will be diagnosed with prostate cancer in the USA this year and more that 31,000 will...
This is an open label, single-center, randomized phase IV pilot study of steroid and calcineurin inhibitor avoidance in renal transplant recipients. All patients will receive two doses of...
Videos
Medical and Biotech [MESH] Definitions
Steroid 16-alpha-hydroxylase
A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.
Gonadal Hormones
Hormones produced by the GONADS, including both steroid and peptide hormones. The major steroid hormones include ESTRADIOL and PROGESTERONE from the OVARY, and TESTOSTERONE from the TESTIS. The major peptide hormones include ACTIVINS and INHIBINS.
Steroid Metabolism, Inborn Errors
Errors in metabolic processing of STEROIDS resulting from inborn genetic mutations that are inherited or acquired in utero.
5-alpha-dihydroprogesterone
A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREGNANOLONE), a neuroactive steroid that binds with GABA(A) RECEPTOR.
Contraception, Postcoital
Means of postcoital intervention to avoid pregnancy, such as the administration of POSTCOITAL CONTRACEPTIVES to prevent FERTILIZATION of an egg or implantation of a fertilized egg (OVUM IMPLANTATION).
