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Treatment of Pain - Biotech, Pharma and Life Science Channel

03:38 EDT 23rd September 2017 | BioPortfolio

PubMed Articles [21795 Associated PubMed Articles listed on BioPortfolio]

Epigenetic Treatment Options in Urothelial Carcinoma.

Mutations, dysregulation, and dysbalance of epigenetic regulators are especially frequent in urothelial carcinoma (UC) compared to other malignancies. Accordingly, targeting epigenetic regulators may ...

Applicability of the direct injection liquid chromatographic tandem mass spectrometric analytical approach to the sub-ngL(-1) determination of perfluoro-alkyl acids in waste, surface, ground and drinking water samples.

The applicability of a direct injection UHPLC-MS/MS method for the analysis of several perfluoroalkyl acids (PFAAs) in a wide range of water matrices was investigated. The method is based on the direc...

Effects and mechanisms of actions of phytochemicals on Alzheimer's disease neuropathology.

Alzheimer's disease affects millions of people, yet, there are only a limited number approaches for it pharmacological treatment. Thus, identifying factors that decrease the risk of developing Alzheim...

Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid dependence.

The interaction of neurotransmitters and genes that control the release of dopamine is the Brain Reward Cascade (BRC). Variations within the BRC, whether genetic or epigenetic, may predispose individu...

LINE-1 as a therapeutic target for castration-resistant prostate cancer.

Prostate cancer is the third leading cause of death by cancer in men. Surgery or hormone deprivation usually contains the progression of the local forms of the disease. In metastatic situations, chemo...

Dissection of prodromal Alzheimer's disease.

Pathophysiological changes of Alzheimer's Disease (AD) begin decades before clinical symptoms become apparent, providing an important window for early diagnosis and intervention. Prodromal stage of AD...

Precision medicine of frontotemporal dementia: from genotype to phenotype.

Frontotemporal dementia (FTD) is the second most common neurodegenerative  cause of early-onset dementia. FTD has an important genetic component contributing to its pathogenic mechanisms. Currently, ...

Leishmaniasis treatment: update of possibilities for drug repurposing.

The leishmaniases represent a public health problem in under-developed countries and are considered a neglected disease by the World Health Organization (WHO). They are cuased by Leishmania  parasite...

Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases.

The trypanosomatid-induced diseases are considered as neglected, because the countries where they kill people are not important markets for western big pharmaceutical companies. However, recently some...

Ibuprofen as a template molecule for drug design against Ebola virus.

The Ebola virus outbreak in West Africa 2015 and Congo 2017, point out an urgent need for development of drugs against this important pathogen. Previously, by repurposing virtual screening of 6438 dru...

News Articles [12993 Associated News Articles listed on BioPortfolio]

Herpes Zoster Shingles Pipeline Review, H2 2017 [Report Updated: 19092017] Prices from USD $2000

Herpes Zoster Shingles Pipeline Review, H2 2017SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Herpes Zoster Shingles Pipeline Review, H2 2017, provides an...

Transdermal Drug Delivery Technologies, Markets, and Companies [Report Updated: 08092017] Prices from USD $3500

Benefits of this reportUptodate onestop information on transdermal drug deliveryDescription of 110 companies involved and 110 collaborations in this areaMarket analysis 20152025/Market values in major...

UPDATING and ADDING: Questcor Pharmaceuticals to Present at Upcoming Investor Conferences in September

ANAHEIM, Calif., Sept. 1, 2011 /PRNewswire/ -- Please replace the release dated August 24, 2011 with the following updated version.  First graph, second and third sentences added and should read:...

Lifetime VIP Member Denise Campbell Has Been Named 2017 Top Female Leader in America

Las Cruces, NM, September 23, 2017 --(PR.com)-- About Denise Campbell, PT, ATC, OCS, Dip. MDT, FAAOMPT Strathmore’s Who’s Who Lifetime VIP Denise Campbell is a member of the Orthopedic, ...

[Articles] Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial

Although combination treatment showed a significant decrease in viral shedding at day 3 relative to monotherapy, this difference was not associated with improved clinical benefit. More work is needed ...

[Comment] Finding the right combination antiviral therapy for influenza

Influenza results in annual epidemics and global pandemics of acute respiratory illness that increases morbidity, mortality, and hospital admissions. Fortunately, there are currently two classes of an...

Bristol-Myers Squibb’s Opdivo® (nivolumab) Receives FDA Approval for the Treatment of Hepatocellular Carcinoma Patients Previously Treated with Sorafenib

Opdivo is the first and only Immuno-Oncology agent to receive this FDA approval; this accelerated approval is based on tumor response rate and durability of response ...

CORRECTING and REPLACING Agilent Technologies Receives Expanded FDA Approval for the Use of Dako PD-L1 IHC 22C3 pharmDx Companion Diagnostic in Gastric or Gastroesophageal Junction (GEJ) Cancer

Patients with gastric or GEJ adenocarcinoma whose tumors express PD-L1 can now be identified for potential treatment with KEYTRUDA® (pembrolizumab) using PD-L1 IHC 22C3 pharmDx ...

Global Health: World Health Officials Describe Progress Against Tetanus, H.I.V. and Malaria

Tetanus in babies has been eliminated from the Americas, experts said. Malaria treatment will be expanded in Africa; new HIV drugs will be available there, too.

Agilent Technologies Receives Expanded FDA Approval for the Use of Dako PD-L1 IHC 22C3 pharmDx Companion Diagnostic in Gastric or Gastroesophageal Junction (GEJ) Cancer

Patients with gastric or GEJ adenocarcinoma whose tumors express PD-L1 can now be identified for potential treatment with KEYTRUDA® (pembrolizumab) using PD-L1 IHC 22C3 pharmDx ...

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Companies [550 Associated Companies listed on BioPortfolio]

BioSensics

BioSensics is a research and product development company specializing in wearable sensors for healthcare, offering innovative monitoring solutions for telehealth, aging-in-place, ...

Cycle Pharmaceuticals

Cycle Pharmaceuticals is committed to changing the way that HT-1 is treated and managed around the world. Cycle Pharmaceuticals has worked for more than four years closely with ph...

Notable Labs

Notable Labs’ mission is to change the way cancer is treated, which starts with putting patients first. The company is developing a personalized treatment service for people ...

Can-Fite BioPharma Ltd.

Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (TASE: CFBI) is an advanced clinical stage drug development Company with a platform technology that is designed to address multi-billion d...

EUSA Pharma

EUSA Pharma is a rapidly growing transatlantic specialty pharmaceutical company focused on in-licensing, developing and marketing late-stage oncology, pain control and critical care products. The ...

OmniGuide, Inc.

OmniGuide, Inc., is the worldwide leader in precision optical scalpels for minimally invasive surgery. OmniGuide CO2 laser fiber products are clinically targeted disposable optical scalpels optimized ...

Post Acute Recovery

Post Acute Recovery (PAR) was founded to become the premier provider of high-quality, cost-effective, outcome-based outpatient addiction and behavioral health treatment in the Uni...

Happify Health

Happify Health (www.HappifyHealth.com) offers evidence-based emotional health behavioral change technology solutions for employers, health plans and enterprise organizations. ...

Cavion, Inc.

Cavion, Inc. is a privately held clinical stage biotechnology company creating therapies modulating the T-type calcium channel (Cav3) for the treatment of neurological diseases. C...

BetterBack

Launched in 2015, BetterBack allows you to effortlessly sit in perfect posture, easing back pain—and preventing it. Lightweight and portable, you can pull it out of a handbag...

Clinical Trials [5379 Associated Clinical Trials listed on BioPortfolio]

Randomized Controlled Trial for Exparel Hip Fracture

This is a prospective, randomized study looking at the effect that a long-acting local anesthetic has on pain control in patients having surgery for hip fractures. The investigators are co...

The Effect of EXPAREL® on Postsurgical Pain, and the Use of Narcotics

Patients undergoing shoulder rotator cuff surgery in an outpatient setting are the focus of this study. The purpose of this study is to determine if the product EXPAREL® can be used as a ...

Hypnosis as a Therapeutic Tool in Patients With Reccurent Cystitis

Half of the women present an episode of cystitis once in their lives. A recurrence occurs in about 20% to 30% of the patients, and half of these patients will make more than 4 episodes per...

Tramadol Versus Placebo in the Management of Postoperative Pain Following Bunionectomy

The study evaluates the effectiveness and safety of IV tramadol compared to placebo managing postoperative pain following a bunionectomy

Membrane Lipid Replacement in Fibromyalgia

The purpose of this study is to determine the clinical effectiveness of an all-natural, patented, Food and Drug Administration (FDA)-approved oral lipid nutritional supplement (NTFactor Li...

Improving Quality of Life in Heart Failure

This research study has been designed to test the efficacy of telephone-delivered Problem-Solving Treatment (PST) for improving the quality of life (QoL) in outpatients with stable heart f...

APRIL CAR T Cells (AUTO2) Targeting BCMA and TACI for the Treatment of Multiple Myeloma

The purpose of this study is to test the safety and efficacy of AUTO2, a CAR T Cell Treatment Targeting BCMA and TACI, in Patients with Relapsed or Refractory Multiple Myeloma.

A Trial of an Online Chronic Pain Treatment for Military, Police and Veterans

The purpose of this study is to evaluate the efficacy of an online acceptance-based behavioural treatment for chronic pain designed for military, police, and veteran populations. Participa...

Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents

Millions of children and adolescents are prescribed opioid pain relievers each year, placing them at risk for serious adverse events and misuse in the home setting. Parents who manage thes...

Effect of Conventional Therapy and Low Level Laser Therapy on Pain and Function in Patients With Temporomandibular Joint Dysfunction

This study to determine the effect of conventional therapy and low level laser therapy on pain and function in patients with temporomandibular joint dysfunction. sixty patients with myofas...

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Medical and Biotech [MESH] Definitions

Persistent pain that is refractory to some or all forms of treatment.

A type of pain that is perceived in an area away from the site where the pain arises, such as facial pain caused by lesion of the VAGUS NERVE, or throat problem generating referred pain in the ear.

A syndrome characterized by retropatellar or peripatellar PAIN resulting from physical and biochemical changes in the patellofemoral joint. The pain is most prominent when ascending or descending stairs, squatting, or sitting with flexed knees. There is a lack of consensus on the etiology and treatment. The syndrome is often confused with (or accompanied by) CHONDROMALACIA PATELLAE, the latter describing a pathological condition of the CARTILAGE and not a syndrome.

An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)

A nonsteroidal anti-inflammatory agent with potent analgesic and antiarthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ankylosing SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).

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