Triggers - Biotech, Pharma and Life Science Channel

15:11 EDT 3rd August 2015 | BioPortfolio

PubMed Articles [555 Associated PubMed Articles listed on BioPortfolio]

Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis.

Hepatocyte cell death, inflammation and oxidative stress constitute key pathogenic mechanisms underlying non-alcoholic fatty liver disease (NAFLD). We aimed to investigate the role of necroptosis in h...

Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs.

NSAIDs are the main triggers of hypersensitivity reactions to drugs. However, the full genetic and molecular basis of these reactions has yet to be uncovered. In this article, we have summarized resea...

A Contingency-Oriented Approach to Understanding Borderline Personality Disorder: Situational Triggers and Symptoms.

This article tested a contingency-oriented perspective to examine the dynamic relationships between in-the-moment borderline personality disorder (BPD) symptom events and in-the-moment triggers. An ex...

Migraine and tension-type headache triggers in a Greek population.

Migraine and tension type headache are the two most common primary headaches. The purpose of this study was to detect differences in clinical characteristics and headache triggers and in a Greek cohor...

Nanoelectroablation of Murine Tumors Triggers a CD8-Dependent Inhibition of Secondary Tumor Growth.

We have used both a rat orthotopic hepatocellular carcinoma model and a mouse allograft tumor model to study liver tumor ablation with nanosecond pulsed electric fields (nsPEF). We confirm that nsPEF ...

Desired and Undesired Effects of Energy Labels-An Eye-Tracking Study.

Saving energy is an important pillar for the mitigation of climate change. Electric devices (e.g., freezer and television) are an important player in the residential sector in the final demand for ene...

Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes.

LPS-induced TLR4 activation alters cellular bioenergetics and triggers proteolytic cleavage of AMPKα and HIF-1α expression in leukocytes. In human leukocytes, and more specifically neutrophils, AMPK...

Sorption and dissolution of bare and coated silver nanoparticles in soil suspensions-Influence of soil and particle characteristics.

The increasing use of silver nanoparticles (AgNPs) in consumer products triggers the need for investigations that improve the understanding of their chemical transformations upon environmental entry. ...

Infant VEPs reveal neural correlates of implicit naming: Lateralized differences between lexicalized versus name-unknown pictures.

Recent behavioural studies with toddlers have demonstrated that simply viewing a picture in silence triggers a cascade of linguistic processing which activates a representation of the picture's name (...

Fast endocytic recycling determines TRPC1-STIM1 clustering in ER-PM junctions and plasma membrane function of channel.

Stromal interaction molecule 1 (STIM1) senses depletion of ER-Ca(2+) store and clusters in ER-PM junctions where it associates with and gates Ca(2+) influx channels, Orai1 and TRPC1. Clustering of TRP...

News Articles [225 Associated News Articles listed on BioPortfolio]

Opexa Therapeutics Announces News Release and Conference Call Schedule to Discuss Second Quarter 2015 Financial Results

Opexa Therapeutics, Inc. (NASDAQ: OPXA), a company developing personalized immunotherapies for autoimmune disorders, including multiple sclerosis (MS) and neuromyelitis optica (NM...

A smarter way to track your asthma symptoms

A new, free-to-download app from non-profit Allergy & Asthma Network could help people better monitor and understand how asthma affects them or their children and provide potentially valuable insi...

Neurobiology: A critical period for brain health

Disrupting a signalling molecule in week-old mice prevents their neurons from altering connections with other neurons in adulthood.Cognitive problems can result from an inability to strengthen or weak...

Health Tip: Triggers of Swimmer's Ear

-- Swimmer's ear occurs when water becomes trapped inside. This can cause pain, inflammation and infection. The American Academy of Otolaryngology -- Head and Neck Surgery says potential triggers incl...

Regenerative medicine: Inhibiting prostaglandin breakdown triggers tissue regeneration

NeuroMetrix Showcases Quell™ Wearable Pain Relief Technology at the American Podiatric Medical Association Annual Scientific Meeting

The Only FDA Cleared Wearable for 24/7 Chronic Pain Relief NeuroMetrix, Inc. (NASDAQ:NURO) today announced that Quell Wearable Pain Relief Technology will be featured at the A...

QIDP for Motif's iclaprim triggers L22M placing

FDA granted Qualified Infectious Disease Product (QIDP) designation to iclaprim from Motif Bio plc (LSE:MTFB) to treat hospital-acquired bacterial pneumonia (HABP), triggering a L22 million ($34.1 mil...

Undercover Video Targets Planned Parenthood; Triggers Calls From GOP Candidates, Officials For Investigations

The video recorded a lunch between two antiabortion activists posing as biotech firm employees and Dr. Deborah Nucatola, Planned Parenthood’s senior director of medical services, in which Nucatola t...

Health Tip: Why Muscles Cramp

-- You've just finished working out, and one of your muscles is cramping and causing lots of pain. The American Academy of Orthopedic Surgeons says possible triggers for muscle cramps include: Forget...

Addictions are Serious! Get Informed Quickly, Urges Psychologist Dr. James Strawbridge in his New Book "Unraveling The Psychological Mystery Of Addictions."

Easy to understand language makes "Unraveling The Psychological Mystery Of Addictions" by Doctor James M. Strawbridge a guide for the addicted and their families. Personal interviews with th...

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Companies [3 Associated Companies listed on BioPortfolio]

BiondVax Pharmaceuticals Ltd

BiondVax is a publicly traded (TASE: BNDX), advanced clinical stage biotech company dedicated to improving protection against influenza, with its lead product a universal influenza (flu) vaccine cal...

MaxPoint Interactive

Using its unique Digital Zip technology, MaxPoint Interactive analyzes billions of data points consumed by neighborhoods across the U.S. such as: offline point of sale data...

Adaptimmune Limited

Adaptimmune Limited is focused on the use of T cell therapy to treat HIV and cancer. It aims to utilize the body’s own machinery – the T lymphocyte cell – to target and destroy can...

Clinical Trials [57 Associated Clinical Trials listed on BioPortfolio]

Comparison Between Clinical and MRI Multiple Sclerosis Activity and Expression of Human Endogenous Retrovirus Type W and Herpesvirus

Multiple sclerosis is the most common autoimmune inflammatory disease of the central nervous system. It is known that your etiology has genetic and environmental causes. Several viruses ha...

Supporting Family Caregivers With Technology for Dementia Home Care

This clinical trial will test the FamTechCare intervention that uses multidisciplinary professional guidance based on in-home video monitoring to support family caregivers in managing chal...

Study Assessing Utility of a Clinical Questionnaire to Identify Subjects With Features of Both Asthma and Chronic Obstructive Pulmonary Disease (COPD)

The primary objective of the study is to identify demographic and non-spirometric clinical features predictive of the asthma-COPD overlap population. The study aims to explore and identify...

Rheolytic Thrombectomy For Adult Intraventricular Haemorrhage

Intraventricular haemorrhage (IVH) - bleeding into the normal fluid spaces (ventricles) within the brain - is associated with a high risk of death or significant long-term disability. IVH ...

Stem Cell Mobilization and VEGF Gene Transfer for Heart Failure

The purpose of this study is to evaluate the safety and bioactivity of intramyocardial gene transfer using VEGF (vascular endothelial growth factor) in patients with ischemic heart failure...

Aerosol IL-2 for Pulmonary Metastases

The goal of this clinical research study is find the highest tolerable dose of interleukin-2 (IL-2) that can be given as an inhaled mist to patients with lung metastases. The safety of thi...

Partners and Alerts: A Study of Social Forces in Medication Adherence

The overall objectives of this study are to improve medication adherence of patients and subsequent health outcomes. This study is designed to examine the existence of strong associations...

Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock

The relationship between shock, ischemia and reperfusion (I/R) injury, hemodynamic instability, systemic inflammatory response syndrome and multiorgan failure has been extensively investig...

FAST Mapping During Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with a prevalence of 8% in the elderly. AF is responsible for frequent hospitalizations, stroke, heart failure and ...

Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit

The primary aim of the study is to evaluate consequences of frailty in critically ill patients. We hypothesize that a higher frailty index (based on published questionnaires) predicts a lo...

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Medical and Biotech [MESH] Definitions

A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.

A constellation of responses that occur when an organism is exposed to excessive cold. In humans, a fall in skin temperature triggers gasping, hypertension, and hyperventilation.

A process fundamental to muscle physiology whereby an electrical stimulus or action potential triggers a myocyte to depolarize and contract. This mechanical muscle contraction response is regulated by entry of calcium ions into the cell.

An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.

A technique that induces the processing of disturbing memories and experiences, by stimulating neural mechanisms that are similar to those activated during REM sleep. The technique consists of eye movements following side-to-side movements of the index and middle fingers, or the alternate tapping of the hands on the knees. This procedure triggers the processing of information, thus facilitating the connection of neural networks.


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