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Triggers - Biotech, Pharma and Life Science Channel

09:07 EDT 30th April 2016 | BioPortfolio

PubMed Articles [563 Associated PubMed Articles listed on BioPortfolio]

Assessment of Hemophilic Arthropathy by Ultrasound: Where Do We Stand?

Joint hemorrhages represent the most common type of bleeding episode in persons with hemophilia, and recurrent hemarthrosis triggers chronic arthropathy, which is the most frequent chronic complicatio...

Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity.

Glioblastoma is the most frequent and malignant brain tumor. Treatment includes chemotherapy with temozolomide concomitant with surgical resection and/or irradiation. However, a number of cases are re...

Chlamydia pneumoniae, and mycoplasma pneumoniae: Are they related to severe asthma in childhood?

Mycoplasma pneumoniae and Chlamydia pneumoniae are frequent agents of acute respiratory diseases and they have been recognized as infectious triggers of asthma.

Rational design of potent and selective inhibitors of an epoxide hydrolase virulence factor from Pseudomonas aeruginosa.

The virulence factor cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory factor (Cif) is secreted by Pseudomonas aeruginosa and is the founding member of a distinct class of epoxide ...

Ventricular fibrillation: triggers, mechanisms and therapies.

Ventricular fibrillation (VF) is a common, life-threatening arrhythmia responsible for significant morbidity and mortality. Due to challenges in safely mapping VF, a comprehensive understanding of its...

The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells.

The endoplasmic reticulum (ER) plays important roles in eukaryotic protein folding and lipid biosynthesis. Several exogenous and endogenous cellular sources of stress can perturb ER homeostasis leadin...

5-Hydroxy-7-Methoxyflavone Triggers Mitochondrial-Associated Cell Death via Reactive Oxygen Species Signaling in Human Colon Carcinoma Cells.

Plant-derived compounds are an important source of clinically useful anti-cancer agents. Chrysin, a biologically active flavone found in many plants, has limited usage for cancer chemotherapeutics due...

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs.

Innate lymphoid cells (ILCs) are critical mediators of mucosal immunity, and group 1 ILCs (ILC1 cells) and group 3 ILCs (ILC3 cells) have been shown to be functionally plastic. Here we found that grou...

Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene.

Humans carry two nearly identical copies of Survival Motor Neuron gene: SMN1 and SMN2. Loss of SMN1 leads to spinal muscular atrophy (SMA), the most frequent genetic cause of infant mortality. While S...

INFECTIOUS DISEASES. Yellow fever outbreak triggers vaccine alarm.

News Articles [213 Associated News Articles listed on BioPortfolio]

HealthLabs.com Offering Half-Off Food Allergy Tests For Month of May

HOUSTON, April 28, 2016 /PRNewswire/ -- HealthLabs.com, an online lab testing company, is featuring a month-long promotion throughout May in honor of Food Allergy Action Month. The self-pay testing bu...

Stress management: Know your triggers

Stress is your body's response to the demands of the world. Identifying your personal triggers is the key to effectively managing your stress.

GOQii Brings First Integrated Wearable and One-on-One Coaching Platform to the U.S.

One of India's Most Popular Health and Wellness Brands Delivers Personalized Lifestyle Coaching With Built-In Accountability and Motivation Triggers MENLO PARK, CA--(Marketwired - Apr 27, Read mor...

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

Group 1 and 3 innate lymphoid cells can be functionally plastic. Humbles and colleagues find that group 2 innate lymphoid cells in the lungs also exhibit phenotypic plasticity after exposure to infect...

Carbohydrate-binding protein triggers inflammation in people with osteoarthritis, says study

In a new study published in the Journal of Immunology, MedUni Vienna researchers managed to identify the function of a carbohydrate-binding protein, known as galectin-1 in patients with osteoarthriti...

Give the Gift of Sleep for Mother's Day

BOULDER, Colo., April 25, 2016 /PRNewswire/ -- Boulder, Colo.-based Sleep Easily (sleepeasily.com) is offering a new gift idea for Mother's Day. It's the Gift of sleep! Sleep Easily is an easy...

CD2 molecule triggers cancer recognition in natural killer cells

A study coordinated by the Malmberg Laboratory at Oslo University Hospital/University of Oslo and the Karolinska Institute, published in Cell Reports, reveals a molecule that trigger cancer recognitio...

New Model Developed to Study ALS

Scientists at University of Florida Health say they have developed a unique mouse model that will allow researchers around the world to better study the genetic origins and potential treatments for ...

Brain's immune system triggers frontotemporal dementia

Frontotemporal dementia (FTD), the second most common cause of dementia in people under 65, may be triggered by a defect in immune cells called microglia that causes them to consume the brain's synapt...

CD2 molecule trigger cancer recognition in natural killer cells

A study reveals a molecule that triggers cancer recognition in natural killer (NK) cells. The study defines an important role for CD2 in stimulating NK cell responses to therapeutic antibodies. The fi...

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Companies [3 Associated Companies listed on BioPortfolio]

BiondVax Pharmaceuticals Ltd

BiondVax is a publicly traded (TASE: BNDX), advanced clinical stage biotech company dedicated to improving protection against influenza, with its lead product a universal influenza (flu) vaccine cal...

MaxPoint Interactive

Using its unique Digital Zip technology, MaxPoint Interactive analyzes billions of data points consumed by neighborhoods across the U.S. such as: offline point of sale data...

Adaptimmune Limited

Adaptimmune Limited is focused on the use of T cell therapy to treat HIV and cancer. It aims to utilize the body’s own machinery – the T lymphocyte cell – to target and destroy can...

Clinical Trials [78 Associated Clinical Trials listed on BioPortfolio]

Mindfulness Meditation for the Treatment of Women With Comorbid PTSD and SUD

The current study will modify an already existing therapy for individuals with substance use disorders to address Post Traumatic Stress Disorder (PTSD) in women enrolled in substance use d...

Protective HA Factors

This is a naturalistic study of 100 migraineurs and 75 post concussive headache patients who will be asked to record their headaches, medications, sleep and other behaviors in a smartphone...

Preventing Risky Drinking in Veterans Treated With Prescription Opioids

Veterans who are taking prescription opioids for chronic pain and are engaging in risky drinking are at heightened risk for drug interactions, including overdose and other negative effects...

Response to Social Rejection in Suicidal Behavior

Suicide is a major health problem that causes annually a million death worldwild. In the stress-vulnerability model, suicidal behavior (SB) results from the interaction between an individu...

Asthma and Pest Control Study: Demonstrating Return-on-Investment for In-Home Pest Control for Children With Persistent Asthma

The New York City Department of Health and Mental Hygiene and Montefiore Medical Center, with the Fund for Public Health of New York (FPHNY), DOHMH's fiscal agent, are partnering on a stud...

Audiovisual Stimulus During Urodynamics

Many women have the need to run to the restroom frequently during the night and day, a condition called "overactive bladder". Embarrassing urinary leakage is also commonly associated with ...

Internet Surveys and Their Impact on Adherence to Brimonidine Topical Gel and QOL in Patients With Rosacea

An investigator-blinded, prospective, 6 month study of subjects with persistent erythema associated with active rosacea will be conducted in 20 subjects aged 18 years and older. All subjec...

A Phase 2 Trial of Neurokinin-1 Receptor Antagonist for the Treatment of Itch in Epidermolysis Bullosa Patients

Itch, or pruritus, is the most common complain reported by patients with epidermolysis bullosa (EB) of all subtypes, and there is no current effective treatment. Itch often triggers scratc...

E-Cigarette Aerosol, Conventional Cigarette Smoke, and Myocardial Perfusion

E-cigarettes deliver nicotine by creating an aerosol of ultrafine particles. Many questions remain about the size and composition and especially about the potential toxicity of these parti...

Endocrine Cardiomyopathy in Cushing Syndrome: Response to Cyclic GMP PDE5 inhibitOrs

Pathophysiology of Cushing's Syndrome (CS) cardiomyopathy is yet unclear and a specific treatment have not been indicated. It was already demonstrated the positive impact of phosphodiester...

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Medical and Biotech [MESH] Definitions

A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.

A constellation of responses that occur when an organism is exposed to excessive cold. In humans, a fall in skin temperature triggers gasping, hypertension, and hyperventilation.

A process fundamental to muscle physiology whereby an electrical stimulus or action potential triggers a myocyte to depolarize and contract. This mechanical muscle contraction response is regulated by entry of calcium ions into the cell.

An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.

A technique that induces the processing of disturbing memories and experiences, by stimulating neural mechanisms that are similar to those activated during REM sleep. The technique consists of eye movements following side-to-side movements of the index and middle fingers, or the alternate tapping of the hands on the knees. This procedure triggers the processing of information, thus facilitating the connection of neural networks.

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