Triggers - Biotech, Pharma and Life Science Channel

02:31 EDT 8th July 2015 | BioPortfolio

PubMed Articles [563 Associated PubMed Articles listed on BioPortfolio]

Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs.

NSAIDs are the main triggers of hypersensitivity reactions to drugs. However, the full genetic and molecular basis of these reactions has yet to be uncovered. In this article, we have summarized resea...

Sorption and dissolution of bare and coated silver nanoparticles in soil suspensions-Influence of soil and particle characteristics.

The increasing use of silver nanoparticles (AgNPs) in consumer products triggers the need for investigations that improve the understanding of their chemical transformations upon environmental entry. ...

Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma.

In polytrauma patients a thoracic trauma is one of the most critical injuries and an important trigger of post-traumatic inflammation. About 50% of patients with thoracic trauma are additionally affec...

The Cytotoxicity of Elderberry Ribosome-Inactivating Proteins Is Not Solely Determined by Their Protein Translation Inhibition Activity.

Although the protein translation inhibition activity of ribosome inactivating proteins (RIPs) is well documented, little is known about the contribution of the lectin chain to the biological activity ...

Controlling the Microstructure of Reverse Micelles and their Templating Effect on Shaping Nanostructures.

Reverse micelles as nonreactors have been most successful in designing nanostructures of different size and shape. Nevertheless, important questions regarding the explicit roles of intrinsic parameter...

Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier.

The bidirectional replication of a circular chromosome by many bacteria necessitates proper termination to avoid the head-on collision of the opposing replisomes. In Escherichia coli, replisome progre...

Novel and recently evolved miRNA clusters regulate expansive F-box gene networks through phasiRNAs in wild diploid strawberry.

The wild strawberry Fragaria vesca has recently emerged as an excellent model for cultivated strawberry as well as other Rosaceae fruit crops due to its short seed-to-fruit cycle, diploidy, and sequen...

A long-term evaluation of cryoballoon ablation in 205 atrial fibrillation patients: a single center experience.

Atrial fibrillation is the most prevalent cardiac arrhythmia with significant healthcare impact with regards to treatment costs, morbidity, and mortality. Many of the focal electrical activities that ...

Tobacco, Nicotine, and Headache.

Migraineurs variably attribute the cause of their headache to tobacco exposure, whereas tobacco is often stated to cause headache-related disability worldwide. Given tobacco's physiological and emotio...

Economic aspects of infertility care: a challenge for researchers and clinicians.

Infertility care has improved remarkably over the last few decades and has received growing attention from health care providers. Several treatments, including expensive options such as Assisted Repro...

News Articles [227 Associated News Articles listed on BioPortfolio]

DOD anthrax debacle triggers broader probe of lab oversight

A search for answers about how a Utah military facility shipped live anthrax to numerous labs has sparked a broader investigation into the oversight of the US Federal Select Agent Program (FSAP), whic...

Disruption of cellular homeostasis induces organelle stress and triggers apoptosis like cell-death pathways in malaria parasite

Sex reversal triggers the rapid transition from genetic to temperature-dependent sex

Sex determination in animals is amazingly plastic. Vertebrates display contrasting strategies ranging from complete genetic control of sex (genotypic sex determination) to environmentally determined s...

A call to fund people not proposals triggers strong reactions online

Researchers debate the merits of funding people on the basis of past performance.

Atmospheric science: Air pollution triggers floods

A catastrophic 2013 flood in China was probably caused, in part, by air pollution.In July 2013, heavy rainfall resulted in a devastating flood in the mountains northwest of the Sichuan Basin in China ...

Water to understand the brain

To observe the brain in action, scientists and physicians use imaging techniques, among which functional magnetic resonance imaging (fMRI) is the best known. These techniques are not based on direct o...

Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells

The second messenger NAADP triggers Ca2+ release from endo-lysosomes. Although two-pore channels (TPCs) have been proposed to be regulated by NAADP, recent studies have challenged this. By generating ...

Narda Safety Test Solutions Interference and Direction Analyzer IDA 2

Narda Safety Test Solutions has expanded the features of its Interference and Direction Analyzer. Spectrograms with a time resolution as fine as 1 μs now allow insights into signal structures that we...

LEAD Recovery Center Celebrates Second Anniversary, Expands Services

Tailored program helps young men develop autonomy and life skills for lasting recovery COSTA MESA, Calif. (PRWEB) July 01, 2015 LEAD Recovery Center, formerly known as Hired Power Breakaway, has anno...

Tissue-type plasminogen activator triggers the synaptic vesicle cycle in cerebral cortical neurons

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Companies [3 Associated Companies listed on BioPortfolio]

BiondVax Pharmaceuticals Ltd

BiondVax is a publicly traded (TASE: BNDX), advanced clinical stage biotech company dedicated to improving protection against influenza, with its lead product a universal influenza (flu) vaccine cal...

MaxPoint Interactive

Using its unique Digital Zip technology, MaxPoint Interactive analyzes billions of data points consumed by neighborhoods across the U.S. such as: offline point of sale data...

Adaptimmune Limited

Adaptimmune Limited is focused on the use of T cell therapy to treat HIV and cancer. It aims to utilize the body’s own machinery – the T lymphocyte cell – to target and destroy can...

Clinical Trials [57 Associated Clinical Trials listed on BioPortfolio]

Comparison Between Clinical and MRI Multiple Sclerosis Activity and Expression of Human Endogenous Retrovirus Type W and Herpesvirus

Multiple sclerosis is the most common autoimmune inflammatory disease of the central nervous system. It is known that your etiology has genetic and environmental causes. Several viruses ha...

Supporting Family Caregivers With Technology for Dementia Home Care

This clinical trial will test the FamTechCare intervention that uses multidisciplinary professional guidance based on in-home video monitoring to support family caregivers in managing chal...

Study Assessing Utility of a Clinical Questionnaire to Identify Subjects With Features of Both Asthma and Chronic Obstructive Pulmonary Disease (COPD)

The primary objective of the study is to identify demographic and non-spirometric clinical features predictive of the asthma-COPD overlap population. The study aims to explore and identify...

Rheolytic Thrombectomy For Adult Intraventricular Haemorrhage

Intraventricular haemorrhage (IVH) - bleeding into the normal fluid spaces (ventricles) within the brain - is associated with a high risk of death or significant long-term disability. IVH ...

Stem Cell Mobilization and VEGF Gene Transfer for Heart Failure

The purpose of this study is to evaluate the safety and bioactivity of intramyocardial gene transfer using VEGF (vascular endothelial growth factor) in patients with ischemic heart failure...

Aerosol IL-2 for Pulmonary Metastases

The goal of this clinical research study is find the highest tolerable dose of interleukin-2 (IL-2) that can be given as an inhaled mist to patients with lung metastases. The safety of thi...

Partners and Alerts: A Study of Social Forces in Medication Adherence

The overall objectives of this study are to improve medication adherence of patients and subsequent health outcomes. This study is designed to examine the existence of strong associations...

Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock

The relationship between shock, ischemia and reperfusion (I/R) injury, hemodynamic instability, systemic inflammatory response syndrome and multiorgan failure has been extensively investig...

FAST Mapping During Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with a prevalence of 8% in the elderly. AF is responsible for frequent hospitalizations, stroke, heart failure and ...

Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit

The primary aim of the study is to evaluate consequences of frailty in critically ill patients. We hypothesize that a higher frailty index (based on published questionnaires) predicts a lo...

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Medical and Biotech [MESH] Definitions

A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.

A constellation of responses that occur when an organism is exposed to excessive cold. In humans, a fall in skin temperature triggers gasping, hypertension, and hyperventilation.

A process fundamental to muscle physiology whereby an electrical stimulus or action potential triggers a myocyte to depolarize and contract. This mechanical muscle contraction response is regulated by entry of calcium ions into the cell.

An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.

A technique that induces the processing of disturbing memories and experiences, by stimulating neural mechanisms that are similar to those activated during REM sleep. The technique consists of eye movements following side-to-side movements of the index and middle fingers, or the alternate tapping of the hands on the knees. This procedure triggers the processing of information, thus facilitating the connection of neural networks.


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