Triggers - Biotech, Pharma and Life Science Channel

07:34 EDT 22nd May 2015 | BioPortfolio

PubMed Articles [565 Associated PubMed Articles listed on BioPortfolio]

An enhanced chemiluminescence resonance energy transfer system based on target recycling G-guadruplexes/hemin DNAzyme catalysis and its application in ultrasensitive detection of DNA.

An enhanced chemiluminescence resonance energy transfer (CRET) system based on target recycling G-guadruplexes/hemin DNAzyme catalysis was developed for ultrasensitive detection of DNA. CRET system co...

Self-contained Photoacid Generator Triggered by Photocy-clization of Triangle Terarylene Backbone.

We herein propose a new type of efficient neutral photoacid genera-tor. A photoinduced 6-electrocyclization reaction of photochromic triangle terarylenes triggers subsequent release of a Brønsted ...

Innate immunity against HIV-1 infection.

During acute HIV-1 infection, viral pathogen-associated molecular patterns are recognized by pathogen-recognition receptors (PRRs) of infected cells, which triggers a signaling cascade that initiates ...

Calcium binding promotes conformational flexibility of the neuronal ca(2+) sensor synaptotagmin.

Synaptotagmin 1 (Syt1) is a synaptic vesicle protein that serves as a calcium sensor of neuronal secretion. It is established that calcium binding to Syt1 triggers vesicle fusion and release of neuron...

Carbamidomethylation side-reactions may lead to glycan misassignments in glycopeptide analysis.

Iodoacetamide is perhaps the most widely used reagent for the alkylation of free sulfhydryls in proteomic experiments. Here we report that both incomplete derivatization of Cys side-chains and overalk...

Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse.

Genetic predisposition and environmental factors influence the development of human autoimmune disease. Occupational exposure to crystalline silica (cSiO2) has been etiologically linked to increased i...

Tetramethoxybenzene is a Good Building Block for Molecular Wires: Insights from Photoinduced Electron Transfer.

Two donor bridge-acceptor molecules with terminal triarylamine and Ru(bpy)3(2+) (bpy = 2,2'-bipyridine) redox partners were synthesized and investigated by cyclic voltammetry, optical absorption, lumi...

Thiosemicarbazone-Pt(II) Complex Causes a Growth Inhibitory Effect on Human Mesenchymal Stem Cells.

We showed the di[3,5-diacetyl-1,2,4-triazolbis(4-cyclohexylthiosemicarbazonato) platinum(II)] complex, (W8), endowed with important antitumor properties. Here, we analysed whether W8 can affect human ...

Walking direction triggers visuo-spatial orienting in 6-month-old infants and adults: An eye tracking study.

The present study investigates whether the walking direction of a biological motion point-light display can trigger visuo-spatial attention in 6-month-old infants. A cueing paradigm and the recording ...

A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis.

Small heat shock proteins (sHSPs) are essential 'holdase' chaperones that form large assemblies and respond dynamically to pH and temperature stresses to protect client proteins from aggregation. Whil...

News Articles [217 Associated News Articles listed on BioPortfolio]

Opexa Therapeutics to Present at the 2015 Marcum Microcap Conference

Opexa Therapeutics, Inc. (NASDAQ: OPXA), a company developing personalized immunotherapies for autoimmune disorders, including multiple sclerosis (MS) and neuromyelitis optica (NM...

Fitch Affirms Cigna's Ratings; Outlook Stable

Fitch Ratings has affirmed Cigna Corp's (Cigna) Issuer Default Rating (IDR) at 'A-' and unsecured senior debt ratings at 'BBB+'. In addition, Insurer Financial Strength (IFS) rati...

Rhode Island Medicaid Overhaul Triggers Opposition

News outlets also report on Medicaid news from North Carolina and Missouri.

Boehringer acquires Pharmaxis' NASH candidate

Boehringer Ingelheim GmbH (Ingelheim, Germany) exercised its option to acquire global rights to anti-inflammatory candidate PXS4728A and related molecules from Pharmaxis Ltd. (ASX:PXS; Pink:PXSLY). Bo...

Nearly Half of Pediatric Medical Errors Deemed Preventable (CME/CE)

(MedPage Today) -- Pilot study aims to identify triggers that cause most medical harms.

Denali's mountain of money

Neurodegenerative disease company Denali Therapeutics Inc. (San Francisco, Calif.) raised $217 million in an untranched series A round -- the second largest series A financing in the industry's histor...

Opexa Therapeutics CEO Invited to Participate in Multiple May Conferences

Opexa Therapeutics, Inc. (NASDAQ:OPXA), a company developing personalized immunotherapies for autoimmune disorders, including multiple sclerosis (MS) and neuromyelitis optica (NMO...

Opexa Therapeutics Announces News Release and Conference Call Schedule to Discuss First Quarter 2015 Financial Results

Opexa Therapeutics, Inc. (NASDAQ: OPXA), a company developing personalized immunotherapies for autoimmune disorders, including multiple sclerosis (MS) and neuromyelitis optica (NM...

Dana-Farber/Boston Children's opens immunotherapy trial for children with leukemia

(Dana-Farber Cancer Institute) Dana-Farber/Boston Children's Cancer and Blood Disorders Center has joined a clinical trial of immunotherapy for children with relapsed or treatment-resistant acute lymp...

LifeMap Reports User-Engagement Findings from ResearchKit App

Clinical Inforamtics News |Two months after announcing their first app built on Apple’s ResearchKit platform, LifeMap Solutions is sharing some of the earliest user-engagement findings from their A...

Events [0 Results]

None

Companies [3 Associated Companies listed on BioPortfolio]

BiondVax Pharmaceuticals Ltd

BiondVax is a publicly traded (TASE: BNDX), advanced clinical stage biotech company dedicated to improving protection against influenza, with its lead product a universal influenza (flu) vaccine cal...

MaxPoint Interactive

Using its unique Digital Zip technology, MaxPoint Interactive analyzes billions of data points consumed by neighborhoods across the U.S. such as: offline point of sale data...

Adaptimmune Limited

Adaptimmune Limited is focused on the use of T cell therapy to treat HIV and cancer. It aims to utilize the body’s own machinery – the T lymphocyte cell – to target and destroy can...

Clinical Trials [55 Associated Clinical Trials listed on BioPortfolio]

Rheolytic Thrombectomy For Adult Intraventricular Haemorrhage

Intraventricular haemorrhage (IVH) - bleeding into the normal fluid spaces (ventricles) within the brain - is associated with a high risk of death or significant long-term disability. IVH ...

Stem Cell Mobilization and VEGF Gene Transfer for Heart Failure

The purpose of this study is to evaluate the safety and bioactivity of intramyocardial gene transfer using VEGF (vascular endothelial growth factor) in patients with ischemic heart failure...

Aerosol IL-2 for Pulmonary Metastases

The goal of this clinical research study is find the highest tolerable dose of interleukin-2 (IL-2) that can be given as an inhaled mist to patients with lung metastases. The safety of thi...

Study Assessing Utility of a Clinical Questionnaire to Identify Subjects With Features of Both Asthma and Chronic Obstructive Pulmonary Disease (COPD)

The primary objective of the study is to identify demographic and non-spirometric clinical features predictive of the asthma-COPD overlap population. The study aims to explore and identify...

Partners and Alerts: A Study of Social Forces in Medication Adherence

The overall objectives of this study are to improve medication adherence of patients and subsequent health outcomes. This study is designed to examine the existence of strong associations...

Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock

The relationship between shock, ischemia and reperfusion (I/R) injury, hemodynamic instability, systemic inflammatory response syndrome and multiorgan failure has been extensively investig...

FAST Mapping During Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with a prevalence of 8% in the elderly. AF is responsible for frequent hospitalizations, stroke, heart failure and ...

Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit

The primary aim of the study is to evaluate consequences of frailty in critically ill patients. We hypothesize that a higher frailty index (based on published questionnaires) predicts a lo...

Environmental Triggers Of Cardiometabolic Disease

The investigators posit that a multi-national collaborative effort with focused investigations in environments with the highest levels of exposure (developing countries such as China and I...

A Study to Compare Treatment With Sirolimus Versus Standard Treatment in Patients Who Have Received a Kidney Transplant

The purpose of this study is to compare treatment with the new drug sirolimus (SRL) versus the standard treatment with cyclosporine (CsA) or tacrolimus in children who have received kidney...

Videos

https://youtube.com/devicesupport

https://youtube.com/devicesupport http://m.youtube.com

Medical and Biotech [MESH] Definitions

A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.

A constellation of responses that occur when an organism is exposed to excessive cold. In humans, a fall in skin temperature triggers gasping, hypertension, and hyperventilation.

A process fundamental to muscle physiology whereby an electrical stimulus or action potential triggers a myocyte to depolarize and contract. This mechanical muscle contraction response is regulated by entry of calcium ions into the cell.

An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.

A technique that induces the processing of disturbing memories and experiences, by stimulating neural mechanisms that are similar to those activated during REM sleep. The technique consists of eye movements following side-to-side movements of the index and middle fingers, or the alternate tapping of the hands on the knees. This procedure triggers the processing of information, thus facilitating the connection of neural networks.

Search BioPortfolio:
Loading
Advertisement
Advertisement
review and buy Triggers market research data and corporate reports here

Channels Quicklinks