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Type 2 RTA - Biotech, Pharma and Life Science Channel

17:10 EDT 18th June 2013 | BioPortfolio

PubMed Articles [ 4227 Associated PubMed Articles listed on BioPortfolio]

Effective treatment of a steroid-induced femoral neck fracture nonunion with a once-weekly administration of teriparatide in a rheumatoid patient: a case report.

INTRODUCTION: Nonunion of femoral neck fractures frequently occurs in elderly patients. In patients with rheumatoid arthritis, reoperation rates after internal fixation of a displaced femoral neck fra...

Brainstem auditory evoked potentials and somatosensory evoked potentials in Chiari malformation.

INTRODUCTION. Chiari malformations (CM) include a series of congenital anomalies involving the descent of the cerebellar tonsils below the foramen magnum, which may be associated with compression in t...

Anthropometric measures and the risk of endometrial cancer, overall and by tumor microsatellite status and histological subtype.

Obesity is an established risk factor for endometrial cancer, but this association is not well understood for subtypes of endometrial cancer. We evaluated the association of recent and adult-life obes...

CXCR3 Deficiency Prolongs Th1-Type Contact Hypersensitivity.

Sensitization and challenge using dinitrofluorobenzene (DNFB) induce contact hypersensitivity (CHS) with Th1 cell infiltration, whereas those using FITC generate CHS with Th2 cell infiltration. In thi...

Analysis of mexicanolide- and phragmalin-type limonoids from Heynea trijuga using high-performance liquid chromatography/electrospray tandem mass spectrometry.

Limonoids, a class of tetranortriterpenoids, exhibit various biological effects, including acting as potent antifeedants and insect growth-regulators against various pests. The analysis of phragmalin-...

Impact of P-glycoprotein and breast cancer resistance protein on the brain distribution of antiepileptic drugs in knockout mouse models.

Refractory epilepsy is reportedly associated with an overexpression of ATP-binding cassette transporters such as P-glycoprotein (Pgp) and breast cancer resistance protein (Bcrp). In this study, we exa...

Myotonic dystrophy type 1 (DM1): A triplet repeat expansion disorder.

Myotonic dystrophy is a progressive multisystem genetic disorder affecting about 1 in 8000 people worldwide. The unstable repeat expansions of (CTG)n or (CCTG)n in the DMPK and ZNF9 genes cause the tw...

A rare family with Hereditary Spastic Paraplegia Type 35 due to novel FA2H mutations: a case report with literature review.

Hereditary Spastic Paraplegia Type 35 is a complicated form of HSP characterized by progressive spastic paraparesis, dysarthria, and mild cognitive decline associated with leukodystrophy on brain imag...

Streptomyces siamensis sp. nov., and Streptomyces similanensis sp. nov., isolated from Thai soils.

Three actinomycete strains, KC-038(T), KC-031 and KC-106(T), were isolated from soil samples collected in the southern Thailand. The morphological and chemotaxonomic properties of strains KC-038(T), K...

Molecular subtyping of early-stage breast cancer identifies a group of patients who do not benefit from neoadjuvant chemotherapy.

The aim of this study was to analyze the correlation between the pathologic complete response (pCR) rate after neoadjuvant chemotherapy and long-term outcome (distant metastases-free survival [DMFS])...

News Articles [ 5001 Associated News Articles listed on BioPortfolio]

Takeda announces availability of type 2 diabetes drugs in US

Takeda Pharmaceutical Company has announced the availability of NESINA (alogliptin) and fixed-dose combinations KAZANO (alogliptin and metformin HCl) and OSENI (alogliptin and pioglitazone) by prescri...

UTC Aerospace Systems supports Airbus A400M certification and first production delivery

CHARLOTTE, N.C., June 18, 2013 /PRNewswire/ --PARIS AIR SHOW --UTC Aerospace Systems proudly supported Airbus Military in securing the A400M's European Aviation Safety Agency (EASA) type certifica...

Special type of IVF may increase risk for insulin resistance among children

A special type of in vitro fertilization, or IVF, may increase the risk for insulin resistance among children conceived in this way, according to a new study from Greece. The results will be presented...

Brain Inflammation Due To Obesity Compounded By Low Testosterone

Low testosterone worsens the harmful effects of obesity in the nervous system, a new study in mice finds. The results were presented at The Endocrine Society's 95th Annual Meeting in San Francisco. "L...

Researchers to study benefits, side effects of four widely used therapies in adults with type 2 diabetes

UT Southwestern Medical Center researchers are seeking 150 adults with type 2 diabetes to take part in the local arm of a major national clinical trial that will compare benefits and side effects of f...

Increasing red meat intake boosts risk of type-2 diabetes mellitus

Eating more red meat over time is associated with an increased risk of type-2 diabetes mellitus (T2DM) in a follow-up of three studies of about 149,000 U.S. men and women, according to a report publis...

Variant Of Main Painkiller Receptor Designed

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing dr...

Paralympic Hopeful's Rare Condition Diagnosed Following Advances In Genetic Sequencing

National Paracycling Champion Tom Staniford has an extremely rare condition which, until now, has puzzled his doctors. He is unable to store fat under his skin - yet has type 2 diabetes - and suffered...

Pharmacological inhibition of myostatin/TGF-β receptor/pSmad3 signaling rescues muscle regenerative responses in mouse model of type 1 diabetes

New risk score could lead to earlier prevention of type 2 diabetes in African Americans

(The Endocrine Society) Researchers have developed a risk assessment scoring system that they believe may better identify certain adults-- especially African Americans-- at high risk of developing typ...

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Companies [ 65 Associated Companies listed on BioPortfolio]

Avaxia Biologics, Inc.

Avaxia is a leader in the growing field of gut-targeted therapeutics — orally administered, minimally absorbed drugs that are designed to act locally in the gastrointestinal...

Defymed

Defymed is a spin -off of the “Centre Europeen d’etude du Diabete”  (CeeD) which has been working on the conception of a bio-artificial pancreas since 1996. This work was ca...

Lincor Solutions

Lincor Solutions, founded in 2003, operates internationally from corporate offices in Nashville, Tennessee, as well as Dublin and Cork, Ireland. With sales offices in Toronto, Can...

Diversified Information Technologies Inc.

Diversified Information Technologies Inc., founded in 1982, is headquartered in Scranton, Pa. Diversified’s solutions manage the complete document and information lifecycle a...

Profectus BioSciences, Inc.

Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...

NanoIntegris, Inc.

NanoIntegris is the world’s only supplier of 99% pure semiconducting and metallic carbon nanotubes. Founded in 2007, NanoIntegris spun out of Professor Mark Hersam’s res...

Ironwood Pharmaceuticals, Inc. & Protagonist Therapeutics, Inc.

Protagonist Therapeutics is a privately held biotechnology company pursuing the discovery and development of disulfide rich peptides (DRPs) as well differentiated alternati...

Genocea Biosciences, Inc.

Genocea Biosciences is a vaccine discovery and development company targeting major infectious diseases with high unmet medical needs, in which T cell responses help confer protect...

Team Type 1

Based in Atlanta, GA, Team Type 1 began as a grassroots initiative to motivate people to take control of their diabetes using cycling as a platform. It grew to become a world-clas...

NeoCell

NeoCell Corporation is a leader in the natural supplement, skin care and health and wellness industries. NeoCell products are designed to promote health, beauty and anti-aging. Th...

Clinical Trials [ 1973 Associated Clinical Trials listed on BioPortfolio]

Oral Collagen for Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by swelling and inflammation of the joints. In RA, the immune system attacks a person's own cells inside joints, eventually...

A Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin.

This 6 arm study will evaluate the efficacy, safety, pharmacokinetics and pharmacodynamics of multiple doses and regimens of a GLP-1 analogue in patients with type 2 diabetes who are treat...

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke

The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the upper limb are effective in treating spasticity in patients after stroke.

A Cross-Sectional Survey to Evaluate Diabetes Management, Control, Complications, Psychosocial Aspects of Patients With Type 2 Diabetes in Bangladesh

This study is conducted in Asia. The aim of this non-interventional study is to evaluate the the current status of diabetes management, control, and complications in diabetic subjects with...

A Study Comparing the Effects and Safety of Dulaglutide With Glimepiride in Type 2 Diabetes Mellitus

The purpose of this study is to examine if once-weekly dulaglutide is efficient and safe compared to glimepiride in participants with type 2 diabetes who have inadequate glycemic control w...

A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin

This study will evaluate the longer-term glycemic effect of two medicines approved for initial treatment of type 2 diabetes. The study consists of a 2 week screening period (2 study visits...

Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes

This Phase 3, open-label, multicenter study is designed to compare the effects of exenatide and insulin glargine (Lantus® injection) on beta-cell function in patients with type 2 diabetes...

Internet Diabetes Self-Management Workshop

The purpose of this study is to determine of the effectiveness of an Internet based Diabetes Self-Management workshop for people with type II diabetes. Half of the people who complete the...

Comparing Self Monitored Blood Glucose (SMBG) to Continuous Glucose Monitoring (CGM) in Type 2 Diabetes

The purpose of this study is to evaluate the use of SMBG and CGM for clinical decisions related to the management of type 2 diabetes. The secondary objective is to determine the benefit o...

Effects of Acute Intake of Caffeinated Beverages in Type 1 Diabetes

The aim of this pilot study is to determine the impact of caffeine-enhanced energy drinks on blood glucose excursion on heart rate, blood pressure, cardiac output and cognitive performance...

Medical and Biotech [MESH] Definitions

Wikstroemia

A plant genus of the family THYMELAEACEAE. Members contain daphnoretin and wikstroelides and daphnane-type DITERPENES.

Deinococcus

A genus of gram-positive aerobic cocci found in the soil, that is highly resistant to radiation, especially ionizing radiation (RADIATION, IONIZING). Deinococcus radiodurans is the type species.

Bacopa

A plant genus of the family SCROPHULARIACEAE. Members contain bacopaside, bacopasaponins and other dammarane type jujubogenins.

Lamin Type A

A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to disassociate from nuclear membranes during mitosis.

Lamin Type B

A subclass of ubiquitously-expressed lamins having an acidic isoelectric point. They are found to remain bound to nuclear membranes during mitosis.

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