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Typhoid Vaccine Wyeth - Biotech, Pharma and Life Science Channel

21:33 EDT 24th July 2014 | BioPortfolio

PubMed Articles [1568 Associated PubMed Articles listed on BioPortfolio]

Effect and mechanisms of curdlan sulfate on inhibiting HBV infection and acting as an HB vaccine adjuvant.

In this study, the effect and mechanisms of curdlan sulfate (CS3) on hepatitis B virus (HBV) infection and promoting immune response of the mice immunized with recombinant hepatitis B surface protein...

Pneumococcal meningitis: A 12 year experience in a children's hospital prior to the universal immunization with a conjugate vaccine.

Introduction. Pneumococcal meningitis is causedby Streptococcuspneumoniae and hashigh morbidity and mortality rates. The objective of this study was to identify the epidemiological and clinical charac...

Pertussis seroprevalence in adults, post-partum women and umbilical cord blood.

Pertussis is a vaccine-preventable disease that affects people of all ages. Young adults who have lost their immunity to pertussis are the major source of infection in infants. Given the steady increa...

Preparation of Triple-Negative Breast Cancer Vaccine through Electrofusion with Day-3 Dendritic Cells.

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) in human immune system. DC-based tumor vaccine has met with some success in specific malignancies, inclusive of breast cancer. In...

Is the "3+3" dose escalation phase 1 clinical trial design suitable for therapeutic cancer vaccine development? A recommendation for alternative design.

Purpose: Phase 1 clinical trials are generally conducted to identify the maximum tolerated dose (MTD) or the biologically active dose (BAD) using a traditional dose escalation design. This design may...

DECORATION OF OUTER MEMBRANE VESICLES WITH MULTIPLE ANTIGENS USING AN AUTOTRANSPORTER APPROACH.

Outer membrane vesicles (OMVs) are spherical nanoparticles that naturally shed from Gram-negative bacteria. They are rich in immunostimulatory proteins and lipopolysaccharide but do not replicate, whi...

Optimization of Storage and Stability of Camel Liver Glutathione S-Transferase.

Glutathione S-transferases (GSTs) are multifunctional enzymes and play an important role in cellular detoxification. Besides this, GSTs act as cytosolic carrier proteins which bind hydrophobic compoun...

An Attenuated Herpes Simplex Virus Type 1 (HSV1) Encoding the HIV-1 Tat Protein Protects Mice from a Deadly Mucosal HSV1 Challenge.

Herpes simplex virus types 1 and 2 (HSV1 and HSV2) are common infectious agents in both industrialized and developing countries. They cause recurrent asymptomatic and/or symptomatic infections, and li...

Incidence of Pneumococcal and Varicella Disease in HIV-Infected Children and Adolescents in the United Kingdom and Ireland, 1996-2011.

To define the burden of hospitalization due to two vaccine preventable infections, invasive pneumococcal disease (IPD) and varicella zoster (VZ), among HIV-infected children in the UK and Ireland.

The Safety and Immunogenicity of Two Hepatitis B Vaccine Formulations (Thiomersal-Free and Thiomersal-Containing) in Healthy Vietnamese Infants: A Phase III, Prospective, Single-Blinded, Randomized, Controlled Trial.

To evaluate the safety and immunogenicity of the thiomersal-free (TF) and thiomersal-containing (TC) formulations of Hepavax-Gene in healthy Vietnamese neonates.

News Articles [2111 Associated News Articles listed on BioPortfolio]

[Comment] Dengue virus and host antibody: a dangerous balancing act

The mosquito-borne dengue virus is a great concern to human health worldwide, leading to 93 million cases per year, many serious. This status is exacerbated by the absence of a vaccine. Despite many a...

[Articles] Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in flavivirus-naive healthy adults in Colombia: a randomised, placebo-controlled, phase 1 study

Our findings emphasise the acceptable tolerability and immunogenicity of the tetravalent DENVax formulations in healthy, flavivirus-naive adults. Further clinical testing of DENVax in different age gr...

Latest Vaccination Coverage Estimates for Adolescents Show Only Small Increase for HPV Vaccine

Centers for Disease Control and Prevention (CDC) officials announced today that the number of girls and boys aged 13-17 years receiving human papillomavirus (HPV) vaccine remains unacceptably low desp...

GSK Asks Europe to OK Malaria Shot

Pharma giant GSK said Thursday it is submitting its malaria vaccine for regulatory approval to the European Medicines Agency. The experimental shot is the most advanced candidate vaccine for malaria...

A first as GlaxoSmithKline files its malaria vaccine

The application will follow the Article 58 procedure, which allows the EMA to assess the quality, safety and efficacy of a product candidate manufactured in an EU member state for a disease recognized...

Too few U.S. youth getting vaccine for sexually transmitted virus: CDC

ATLANTA (Reuters) - More U.S. adolescents are receiving vaccines against the sexually transmitted virus that causes cervical and other types of cancer but vaccination rates for the infection remain to...

World’s first Malaria Vaccine Submitted for Approval to EMA

GlaxoSmithKline submits the first malaria vaccine for approval by the European Medicines Agency and the World Health Organization The vaccine, named RTS,S, targets Plasmodium falciparum parasite. Thi...

GSK files EU regulatory submission for RTS,S malaria vaccine candidate

UK pharma giant GlaxoSmithKline announced today that it has submitted a regulatory application to the European Medicines Agency for its malaria vaccine candidate, RTS,S.

Top 3 Sparks of Interest for Leading Vaccine Academics

Recently we undertook the research for the 15th annual World Vaccine Congress. As part of that research, we spoke to leading vaccine academics from the likes of University of Oxford and Erasmus MC to...

GSK files malaria vaccine with EMA for use in Africa

GSK files malaria vaccine with EMA for use in Africa

Events [1 Associated Events listed on BioPortfolio]

Cancer Vaccines 2014

Cancer Vaccines 2014 | Quantify Strategies to Enhance Cancer Vaccine Research and Development

Companies [81 Associated Companies listed on BioPortfolio]

Biosceptre

Biosceptre has identified a pan-cancer target, present in many cancer types, and importantly not found in healthy tissue. Early research and initial evidence suggest that drugs di...

TNG Pharmaceuticals, Inc.

TNG Pharmaceuticals is a Louisville, KY based animal pharmaceutical company focused on the development of its patented vaccine for cattle, FlyVax™, to aid in control of the h...

PaxVax Inc.

PaxVax is a privately held specialty vaccine company founded in 2007. PaxVax is focused on traveler vaccines with an emerging pipeline in biodefense coupled with a social mission...

ImmusanT Inc.

ImmusanT is a privately-held biotechnology company focused on restoring tolerance to gluten in celiac disease by harnessing new discoveries in immunology that aim to improve diagn...

Etubics Corporation

Etubics Corporation, based in Seattle, Wash., is a clinical stage bio-pharmaceutical company, which has developed a proprietary platform technology consisting of a next generation...

Nuron Biotech, Inc.

Nuron Biotech is developing novel biologics and vaccines for the prevention and treatment of neurodegenerative and infectious diseases. Its team of industry veterans is committed...

OncoPep, Inc.

OncoPep is developing targeted immunotherapeutics to prevent the progression of cancer, prolong survival and restore the quality of life of patients. OncoPep’s lead program i...

PaxVax, Inc.

PaxVax is a privately held company committed to developing better vaccines to better the world. Established in 2007, PaxVax has a clinical-stage product portfolio, including a cho...

Hookipa Biotech AG

Hookipa Biotech, founded in Vienna, Austria in summer 2011, develops a new class of innovative prophylactic and therapeutic vaccines based on its proprietary Vaxwave® technology. The Vaxwave&r...

The Vaccine and Gene Therapy Institute of Florida (VGTI Florida)

“We dedicate ourselves every single day to finding novel treatments for chronic diseases like cancer and HIV/AIDS,” said Mel Rothberg, Chief Operating Officer, VGTI Flor...

Clinical Trials [2014 Associated Clinical Trials listed on BioPortfolio]

Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in Niger

The study is a double-blinded, randomized, placebo-controlled, trial with two groups of infants receiving vaccine or placebo to assess the efficacy and safety of BRV-PV. Three doses of BRV...

Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy Adults

This Phase 1 clinical trial is aimed to evaluate the safety and immunogenicity of 3 doses of a candidate vaccine against Shigella sonnei (1790GAHB vaccine) when administered at different d...

The Safety and Immunogenicity of a Potential HIV Vaccine

The potential HIV vaccine has two components: a protein immunogen based on the coat protein of HIV; and an adjuvant which enhances the vaccinee's response to the immunogen. The immunogen i...

ICI-VPH: Impact of HPV Immunisation Schedules Against HPV

This randomised clinical trial aims to determine whether an immunization schedule comprising two doses of Gardasil administered six months apart is non-inferior to a schedule comprising th...

iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma/VEGAS

The purpose of this study is to find the largest safe dose of GD2-T cells (also called iC9-GD2-CAR-VZV-CTLs), and additionally to evaluate if a VZV vaccine can improve the expansion and pe...

Safe Administration of Flu Vaccine to Egg Allergic Children

Historically, providing influenza vaccination of egg allergic children and young adults (EAC) with a history of anaphylaxis to egg, or other severe symptoms of an allergic reaction to egg...

Evaluating the Safety and Immune Response to Two Doses of a Dengue Virus Vaccine Administered 12 Months Apart

Dengue viruses can cause dengue fever and other more severe forms of disease. This study will evaluate the safety and immune response to two doses of a dengue virus vaccine given 12 months...

Study of the Safety and Immunogenicity of a Novel H5N1 Influenza Vaccine in Healthy Adults Age 18-49

The purpose of this study is to test an investigational vaccine known as "VAX161C." An "investigational" vaccine is one that is not licensed for commercial use in the by the United States...

A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract

Head and neck squamous cell carcinoma (HNSCC) is a lethal solid malignancy with 5 year survival estimates of approximately 50%, and is associated with a high rate of systemic immune impair...

Safety and Immunogenicity of PanBlok Influenza Vaccine in Healthy Adults

The purpose of this study is to investigate the safety and immunogenicity of a recombinant hemagglutinin (rHA) influenza vaccine derived from A/Indonesia/05/2005 (H5N1) administered at 3 d...

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Medical and Biotech [MESH] Definitions

A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.

A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)

A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.

A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.

Vaccines used to prevent TYPHOID FEVER and/or PARATYPHOID FEVER which are caused by various species of SALMONELLA. Attenuated, subunit, and inactivated forms of the vaccines exist.

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