Variant Forms of Lupus - Biotech, Pharma and Life Science Channel

02:16 EDT 31st October 2014 | BioPortfolio

PubMed Articles [4572 Associated PubMed Articles listed on BioPortfolio]

Determination of α- and β-boldenone sulfate, glucuronide and free forms, and androstadienedione in bovine urine using immunoaffinity columns clean-up and liquid chromatography tandem mass spectrometry analysis.

The debate about the origins of boldenone in bovine urine is ongoing for two decades in Europe. Despite the fact that its use as a growth promoter has been banned in the European Union (EU) since 1981...

Metals in boat paint fragments from slipways, repair facilities and abandoned vessels: An evaluation using field portable XRF.

Paint flaking off abandoned vessels or generated during boat repair is hazardous to human health and wildlife. In this study, a means of screening paint fragments using a field portable-X-ray fluoresc...

Isolation and purification of versican and analysis of versican proteolysis.

Versican is a widely distributed chondroitin sulfate proteoglycan that forms large complexes with the glycosaminoglycan hyaluronan (HA). As a consequence of HA binding to its receptor CD44 and interac...

The detection of glycosaminoglycans in pancreatic islets and lymphoid tissues.

In this chapter, we describe the detection of the glycosaminoglycans hyaluronan and heparan sulfate in pancreatic islets and lymphoid tissues. The identification of hyaluronan in tissues is achieved b...

Glycosaminoglycan-protein interaction studies using fluorescence spectroscopy.

Fluorescence spectroscopy is a quantitative analytical tool that has been extensively used to provide structural and dynamical information on GAG-protein complexes. It possesses major advantages inclu...

Efficacy of supplementation of selected medicinal mushrooms with inorganic selenium salts.

The aim of the study was to evaluate the possibility of supplementation with inorganic forms of selenium (Na2SeO4 and Na2SeO3) in concentrations of 0, 0.1, 0.2, 0.4, 0.6, 0.8, 1.0 and 1.5 mM of three...

Biomarkers of Plaque Instability.

Atherosclerosis is the proximate cause of arterial thrombosis, leading to acute occlusive cardiovascular syndromes. Thrombosis in atherosclerosis usually results from rupture of the fibrous cap of ath...

Glucokinase MODY and Implications for Treatment Goals of Common Forms of Diabetes.

Treatment goals in diabetes concentrate on reducing the risk of vascular complications, largely through setting targets for glycated haemoglobin (HbA1c). These targets are based on epidemiological stu...

Bone as an Endocrine Organ Relevant to Diabetes.

There are well-established associations between diabetes and fracture risk and yet the mechanism underlying these associations are controversial. Guided by a series of mouse studies, a specific form o...

Determination of four forms of vitamin B12 and other B vitamins in seawater by liquid chromatography/tandem mass spectrometry.

Vitamin B12 is an essential nutrient for more than half of surveyed marine algae species, but methods for directly measuring this important cofactor in seawater are limited. Current mass spectrometry ...

News Articles [1260 Associated News Articles listed on BioPortfolio]

Genetic variant in NDUFS1 gene is associated with schizophrenia and negative symptoms in Han Chinese

Cirrus Pharmaceuticals, a Kemwell company, to invest in cGMP Manufacturing Suite in US

Cirrus Pharmaceuticals, a Kemwell company, which is a 100% services oriented company providing pharmaceutical contract development and manufacturing services, announced that it wi...

Cartagenia Launches Advanced Genetic Variant Assessment Platform for NIH Undiagnosed Disease Program

BOSTON and BETHESDA, Md., Oct. 30, 2014 /PRNewswire/ -- Cartagenia, a leader in providing genetic labs and clinicians with software-based workflow support for variant assessment, lab reporting, and in...

Study Says Blood Test for Brain Insulin Resistance Accurately Predicts Alzheimer’s Disease Risk

Technology May Be Useful in Measuring the Prognosis and Treatment of Alzheimer’s Disease Brain insulin resistance is an abnormality in Alzheimer’s disease that cont...

DPT Expands Capacity with New High-Speed Bottle-Filling Center at San Antonio Site

CDMO DPT Laboratories, a specialist in semi-solid and liquid dosage forms, announced that it has implemented a high-speed bottle-filling center at its San Antonio location.

Comparative Dissolution Profile – A Quality Control Tool

In vitro methods to measure the dissolution rate of the API from the solid oral form are officially recognized by regulatory agencies as an important consideration when formulating solid-oral-dosa...

Dr. Joseph Furlin Launches New Website with Information about Care Services

Dr. Joseph Furlin has recently launched a new website for his practice that contains important information about his care services in obstetrics and gynecology. Chicago, IL (PRWEB) October 30, 2014 D...

Lupus Research Institute Awards $1-Million Grants to Discover What Causes Lupus

NEW YORK, Oct. 30, 2014 /PRNewswire/ -- The Lupus Research Institute (LRI) announced recipients of its 2014 Distinguished Innovator Awards with three cutting-edge projects that tackle the underly...

Merck Forms a Scientific Partnership with Kenya Medical Research Institute (KEMRI) as part of its Capacity Advancement Program in Africa

Merck announced today the signature of a memorandum of understanding with Kenya Medical Research Institution (KEMRI) for a scientific partnership aimed at contributing to the country’s social and ec...

New Imaging Technique Leads to Better Understanding of Freezing in Plants

U.S. Department of Agriculture (USDA) agronomist David P. Livingston has used an imaging technique to see what happens to oats when they freeze. Oats do not grow in many northern areas in the US becau...

Events [0 Results]

None

Companies [91 Associated Companies listed on BioPortfolio]

tesa Labtec GmbH

With more than 20 years of experience, tesa Labtec is one of the leading drug delivery companies for film-shaped dosage forms like patches and oral films. Based on its innovative ...

Binary Fountain, Inc.

Binary Fountain is a leading social intelligence company that extracts operational feedback from online conversations and distills the results into actionable insights. The compan...

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

TherapeuticsMD Inc.

TherapeuticsMD Inc. is an innovative healthcare company focused on developing and commercializing products exclusively for women. TherapeuticsMD is developing advanced hormone the...

BioFilm, Ltd.

Founded in 2003 as a subsidiary of Devro plc., BioFilm is the largest Thin Dissolving Film (TDF) producer in Europe, with their GMP certified manufacturing and packaging facility ...

Sunrise Senior Living, LLC

Sunrise Senior Living, a McLean, Va.-based company, employs approximately 29,000 people. As of April 1, 2014, Sunrise operated 290 communities in the United States, Canada and the...

Sunrise Senior Living and Health Care REIT, Inc.

Sunrise Senior Living, a McLean, Va.-based company, employs approximately 29,000 people. As of January 1, 2014, Sunrise operated 290 communities in the United States, Canada and t...

DNAtrix Inc.

DNAtrix is a company developing modified oncolytic viruses for the treatment of the most aggressive forms of cancer. Since viruses are already efficient at killing cells, scientis...

Alector LLC

Alector is combining state-of-the-art antibody technology and recent discoveries in neuroimmunology and human genetics to develop novel therapeutics for Alzheimer’s disease, ...

DataMotion

DataMotion enables organizations to dramatically reduce the cost and complexity of delivering electronic information to employees, customers and partners in a secure and compliant...

Clinical Trials [545 Associated Clinical Trials listed on BioPortfolio]

Prevalence and Predictors of Neurocognitive Impairment Among HIV-infected Patients

Despite the advent of highly active antiretroviral therapy (HAART), the prevalence of neurocognitive impairment among HIV-infected patients continues to be an important issue. Although sev...

Plerixafor for Stem Cell Mobilization in Normal Donors

The goal of this clinical research study is to learn if treating stem cell donors with filgrastim (G-CSF) and plerixafor (Mozobil®) can cause them to produce a higher number of blood stem...

PEU in Elderly TCU Residents

Background: There is tremendous controversy regarding the adequacy/effectiveness of the nutritional care provided in VA Transitional Care Units (TCUs). The interrelationship between concur...

Environmental Risk Factors for Myositis in Military Personnel

Background: - Myositis is a rare disease in which the body s immune cells attack the muscle tissue. It can cause muscle weakness, swelling, and pain. It can develop in people wi...

A 24 Week Open Label Study of the Utility of Adalimumab in Active Axial Forms of Psoriatic Arthritis

Based on published data and according to the approved product label for ankylosing spondylitis and psoriatic arthritis, it can be expected that adalimumab 40 mg every 14 days should be eff...

A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults

To evaluate the efficacy and safety of sifalimumab compared to placebo in subjects with moderately to severely active Systemic Lupus Erythematosus (SLE).

Efficacy and Safety of Belimumab in Patients With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy, safety, and tolerability of belimumab in adult patients with active lupus nephritis.

A Pilot Study of Lithium in Progressive Multiple Sclerosis

The purpose of this study is to determine whether lithium carbonate is safe, well-tolerated, and effective at treating progressive forms of multiple sclerosis.

Omalizumab for Lupus

Background: - Systemic Lupus Erythematosus (SLE or lupus) is an autoimmune disease, which means the body's immune system mistakenly attacks healthy tissue resulting in inflammatio...

Hematopoietic Stem Cell Support in Vasculitis

The systemic vasculitis is a wide-ranging group of diseases that are characterized by the presence of blood vessel inflammation (1). Despite this common feature, each type of vasculitis h...

Medical and Biotech [MESH] Definitions

A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems. It has been classified into three forms - acute (= LUPUS ERYTHEMATOSUS, SYSTEMIC with skin lesions), subacute, and chronic (= LUPUS ERYTHEMATOSUS, DISCOID).

Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).

A type of lupus erythematosus characterized by deep dermal or subcutaneous nodules, most often on the head, face, or upper arms. It is generally chronic and occurs most often in women between the ages of 20 and 45.

The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.

Search BioPortfolio:
Loading
Advertisement
Advertisement
review and buy Variant Forms of Lupus market research data and corporate reports here

Channels Quicklinks