Vascular access complications - Biotech, Pharma and Life Science Channel
PubMed Articles
A series of α-substituted nitroolefins were employed in organocatalytic asymmetric Michael reactions with aldehydes. γ-Nitro carbonyl products were achieved in good yields (up to 86%) with good ster...
Automated solid phase synthesis of oligoarabinofuranosides.
Automated solid phase synthesis enables rapid access to the linear and branched arabinofuranoside oligosaccharides. A simple purification step is sufficient to provide the conjugation ready oligosacch...
Synthesis and pharmacology of proteasome inhibitors.
Shortly after the discovery of the proteasome it was proposed that inhibitors could stabilize proteins which ultimately would trigger apoptosis in tumor cells. The essential questions were whether sma...
The cupreidinium salt 1 catalyzes the highly enantioselective conjugate addition of nitromethane to β-aryl-β-trifluoromethyl aryl enones (2). The biologically important chiral pyrrolines 4 and N-oxi...
An atom-economical and stereoselective domino synthesis of functionalised dienes.
Open sesame: A direct synthesis of functionalised and stereodefined dienes, relying on a domino allylic alkylation/electrocyclic ring-opening sequence, is reported. This method allows concise access t...
Quo vadis? The Lewis acid catalyzed reaction of (hetero)aryl-derived donor-acceptor cyclopropanes with alkenes can be selectively directed along a [3+2] annulation pathway. This new process provides c...
The first catalytic enantioselective 1,3-dipolar cycloaddition of azomethine ylides to α-aminoacrylate catalyzed by a AgOAc/ferrocenyl oxazolinylphosphine (FOXAP) system was developed, which exhibits...
BACKGROUND: Current rates of survival for gastric cancer patients are much improved compared with those of the past. The purpose of our study was to analyze the survival of gastric cancer patients acc...
Integrin β4 and its Y-1494 phosphorylation play an important role in cell signaling. We found a small molecule, ethyl1-(3-(4-chlorophenoxy)-2-hydroxypropyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxyla...
Parental health information seeking and re-exploration of the 'digital divide'
Aim: To describe patterns of 'online' and 'offline' health information seeking in families with children under five years of age and living in five socially, economically and culturally disparate loca...
News Articles
Study: VEGF inhibitor appears to improve glaucoma surgical outcomes
The most common cause of failure after glaucoma surgery is scarring at the surgical site, so researchers are actively looking for ways to minimize or prevent scar formation. Previous work had suggeste...
Type: Original PaperPurposeWe hypothesized that combined delivery of vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang-1) using microsphere/hydrogel hybrid systems could enhance mature...
CDC Protocols Cut Dialysis Bloodstream Infections in Half
ATLANTA—Today, the Centers for Disease Control and Prevention (CDC) released results of its Dialysis Bloodstream Infection Prevention Collaborative showing a 32 percent decrease in overall bloodstre...
Lab Notes: Cell Therapy May Rescue Veins in CKD
(MedPage Today) -- An intravenous infusion of endothelial cells improved vascular function in a mouse model of chronic kidney disease, researchers said. Also this week: another reason not to tailgate...
New Study Recommends Using Active Videogaming (“Exergaming”) to Improve Children’s Health
SOURCE: Elsevier DESCRIPTION:Cincinnati, OH, May 17, 2013 /3BL Media/ – Levels of physical inactivity and obesity are very high in children, with fewer than 50% of primary school-aged boys and fewer...
New study pinpoints biochemical mechanism underlying fibrosis following glaucoma surgery
(Elsevier Health Sciences) The most common cause of glaucoma surgery failure is scarring at the surgical site.Previous work had suggested that vascular endothelial growth factor (VEGF) inhibition resu...
Cystic fibrosis patients in Wales to get access to ivacaftor
Cystic fibrosis patients in Wales are to have access to ivacaftor (Kalydeco), despite the All-Wales Medicines Strategy Group advising that the drug should not be made available on the NHS. In a s...
Teleflex to Focus on Arrow® Advanced Interventional Radiology Portfolio at EuroPCR
Teleflex Incorporated (NYSE: TFX), a leading global provider of medical devices for critical care and surgery, will showcase its interventional radiology solutions at the European...
Cochrane researchers continue to face challenges over access to data on flu drugs
bmj;346/may16_4/f3190/FIGF1figCochrane Collaboration researchers have said that they may be unable to analyse clinical trial data given to them by GlaxoSmithKline (GSK) on the antiviral drug...
Patients Honor Dr. James Pollock, Maj., USAF (Ret.), SOCOM, WW for Compassion
STUART, Fla., May 16, 2013 /PRNewswire-USNewswire/ -- Patients' Choice has announced that Dr. James Pollock, Maj., USAF (Ret.), SOCOM, WW was one of a select few physicians honored with the prestigiou...
Events
Diabetes: Secondary Complications, Regulation and Innovation Conference
SMi is very proud to present our 11th conference focusing on Diabetes and metabolic disorders taking place on 1st and 2nd Oct 2013, London.
Companies
AmeriHealth HMO, Inc. and AmeriHealth Insurance Company of New Jersey (collectively, âAmeriHealth New Jerseyâ) provide health insurance coverage to employers and individ...
Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, a...
Amerigroup, a Fortune 500 Company, coordinates services for individuals in publicly funded health care programs. Serving approximately 1.9 million members in 11 states nationwide, Amerigroup accepts a...
BIOTRONIK® is a leading European company in the field of biomedical technology. Our main focus is on the business sectors of electrotherapy of the heart and vascular intervention. Our products help p...
CarMax, a member of the FORTUNE 500 and the S&P 500, and a FORTUNE â100 Best Companies to Work Forâ for nine consecutive years, is the nationâs largest retailer of...
Navix Diagnostix is a full-service outsource provider of cardiovascular diagnostic services to hospitals and multi-speciality, cardiology and vascular surgery physician practices....
On July 29th, IBM announced that it has entered into a definitive agreement to acquire Storwize. The acquisition is anticipated to close in the third quarter of 2010, subject to t...
Founded in 2000, Array Networks is a global leader in enterprise secure application delivery and universal access solutions for rapidly growing SSL VPN and application acceleratio...
Paradigm Medical Management, Inc
Paradigm Medical Management, Inc (PMM) headquartered in Los Angeles, California, is an industry leader focused on the development, implementation and management of hospital outpat...
Xirrus, Inc., the only Wi-Fi Power Play in the industry, manufactures the High Performance Wi-Fi Array, which is the only fully distributed, dense radio Wi-Fi architecture...
Clinical Trials
Nephrotic Syndrome Study Network
Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and Membranous nephropathy (MN), generate an enormous individual and societal financial burden, accounting for appr...
Screen-and-treat approach reduces postabortal pelvic inflammatory disease after induced abortion, and at the same time alters women's sexual behavior and prevents further re-infection by s...
Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression
Psychological therapies for depression have demonstrated efficacy, but outcomes are still unsatisfactory, especially in cases with high comorbidity. Depression and anxiety co-occur in up t...
Parkinson's Disease Registry of the Muhammad Ali Parkinson Center
The purpose of the Parkinson’s disease Registry is to develop a national and international database of persons with Parkinson’s disease (PD). The Registry will be used to facilitate t...
Can Tadalafil Maintain Erectile Function In Patients Treated With Radiotherapy For Prostate Cancer?
Because of the high incidence of post-radiation erectile dysfunction (ED), up to 72% after external-beam radiotherapy, this patient category represents a most difficult therapeutic challen...
Effects of Anemia Correction on Vascular and Monocyte Function in Renal Transplant Recipients
Correction of anaemia in renal transplant recipients by parenteral application of recombinant erythropoietin and if necessary iron will improve large artery function (endothelial function...
Chronic transplant nephropathy and cardiovascular death are the main reasons for loss of transplanted organs after kidney transplantation. Vascular changes, induced by hypertension and/or...
Glitazones and Endothelial Function (GATE)
The purpose of the study is to determine if the addition of rosiglitazone to subjects with fair glucose control on other oral agents improves endothelial function, a surrogate marker of va...
Study of the Use of Coated Venous Catheters in the Critically Ill Child
This study should help determine to determine whether or not the use of an antibiotic coated catheter will significantly reduce the number of central line related bloodstream infections in...
Use of a Ureteral Access Sheath During Ureteroscopy and Its Effect on Stone Free Rate
Patients with upper ureteral or renal stones will be randomized to undergoing ureteroscopy with or without a ureteral access sheath. The sheath is designed to facilitate ureteroscope inser...
Videos
3M Satellite Symposium - Reducing Complications in Vascular Access - WoCoVA 2012
In the first of two presentations, Mark Rupp, MD, will review the clinical significance and pathogenesis of intravascular-catheter-related bloodstream infect...
Medical and Biotech [MESH] Definitions
Patient Access To Records
The freedom of patients to review their own medical, genetic, or other health-related records.
Hepatophyta
A plant division. They are simple plants that lack vascular tissue and possess rudimentary rootlike organs (rhizoids). Like MOSSES, liverworts have alternation of generations between haploid gamete-bearing forms (gametophytes) and diploid spore-bearing forms (sporophytes).
Integrin Alphavbeta3
An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).
Pubmed
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Neuropilins
Neuropilins are 140-kDa vertebrate cell surface receptors that bind neuronal guidance molecules during neural development and axonal outgrowth, and modulate VEGF-mediated angiogenesis. NEUROPILIN-1 and NEUROPILIN-2 differ in their binding specificities, and are distributed complementarily in regions of the developing nervous system. Neuropilins are receptors for secreted CLASS 3 SEMAPHORINS as well as for vascular endothelial growth factors, and may form hetero- or homodimers. They may also interact synergistically with plexins and with VEGF RECEPTORS to form receptor complexes with distinct affinities and specificities. Neuropilin binding specificity is determined by CUB and coagulation-factor-like domains in the extracellular portion of the molecule, while a MAM domain is essential for SIGNAL TRANSDUCTION.
