Viral Conjunctivitis - Biotech, Pharma and Life Science Channel
PubMed Articles
The dengue capsid protein C is a highly basic alpha-helical protein of ∼100 amino acid residues that forms an emphipathic homodimer to encapsidate the viral genome and to interact with viral membran...
We examined the formation, participation, and functional specialization of virus-reactive Foxp3(+) regulatory T cells (Tregs) in a mouse model of influenza virus infection. "Natural" Tregs generated i...
Immunization with vaccinia virus elicits a protective Ab response that is almost completely CD4(+) T cell dependent. A recent study in a rodent model observed a deterministic linkage between Ab and CD...
HSV type 1 (HSV-1)-specific CD8(+) T cells provide immunosurveillance of trigeminal ganglion (TG) neurons that harbor latent HSV-1. In C57BL/6 mice, the TG-resident CD8(+) T cells are HSV specific and...
Discovery of pyrido2,3-dpyrimidine-based inhibitors of HCV NS5A.
Efforts to improve the genotype 1a potency and pharmacokinetics of earlier naphthyridine-based HCV NS5A inhibitors resulted in the discovery of a novel series of pyrido[2,3-d]pyrimidine compounds, whi...
Viral infections can exacerbate multiple sclerosis (MS) through poorly defined mechanisms. We developed an experimental system whereby infection with an asymptomatic neurotropic alphavirus caused a tr...
NO-hybridization of the HIV protease inhibitor Saquinavir generates a new chemical entity named Saq-NO, that retains the anti-viral activity and exerts lower toxicity. We show that Saq-NO inhibited th...
The subthalamic nucleus (STN) of the basal ganglia plays a key role in motor control, and STN efferents are known to mainly target the external segment of the globus pallidus (GPe), entopeduncular nuc...
Viral infections of the ovary can cause pathological conditions. However, innate antiviral responses in the ovary are poorly understood. In this study, we demonstrate that Toll-like receptor 3 (TLR3),...
Metastatic tumor antigen 1 (MTA1) overexpression is closely associated with postoperative recurrence of hepatocellular carcinoma (HCC). It has been suggested that pegylated interferon (Peg-IFN) can pr...
News Articles
G-Sphere Standard for Molecular Norovirus Assays The G-Sphere range of Molecular Standards from Phthisis Diagnostics has expanded to include both parasites and viruses. Synthetic controls for No...
Genetics of cervical cancer raise concern about antiviral therapy in some cases
(Oregon State University) A new understanding of the genetic process that can lead to cervical cancer may help improve diagnosis of potentially dangerous lesions for some women, and also raises a warn...
LabCorp offers Roche's viral load assay for hepatitis C virus
Laboratory Corporation of America Holdings (LabCorp) has become the first clinical reference laboratory to offer Roche COBAS AmpliPrep/COBAS TaqMan HCV Test, v2.0, a viral load assay for hepatitis C v...
Boehringer Ingelheim Hepatitis C Phase III Trials: 85% Of Japanese Show Sustained Viral Response
In Phase III hepatitis C trials using the protease inhibitor faldaprevir and pegylated interferon ribavirin carried out by Boehringer Ingelheim, 85% of Japanese participants displayed a sustained vira...
Age disparities exist in continuum of care for patients with HIV
Age disparities exist in the continuum of care for patients with the human immunodeficiency virus (HIV) with people younger than 45 years less likely to be aware of their infection or to have a suppre...
Computer modeling technique goes viral at Brandeis
(Brandeis University) Sophisticated computational models and advances in graphical processing units are helping scientists understand the complex interplay between genomic data, virus structure and th...
LabCorp provides viral load assay for Hepatitis C Virus in US
Laboratory Corporation of America Holdings (LabCorp) is offering the COBAS AmpliPrep/COBAS TaqMan HCV Test, v2.0, a quantitative viral load assay for Hepatitis C virus (HCV).
Mathematical Models Being Used In The Fight Against Cancer
Here's a good reason to pay attention in math class. Nature Communications has published a paper from Ottawa researchers, outlining how advanced mathematical modelling can be used in the fight against...
LabCorp Announces Availability of Newly Approved Viral Load Assay for Hepatitis C Virus
LabCorp becomes the First Major Clinical Reference Laboratory to Offer the Roche COBAS AmpliPrep/COBAS TaqMan HCV Test, v2.0 Laboratory Corporation of America® Hold...
Study details age disparities in HIV continuum of care
Age disparities exist in the continuum of care for patients with the human immunodeficiency virus (HIV) with people younger than 45 years less likely to be aware of their infection or to have a suppre...
Events
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Companies
Institute of Human Virology (IHV) at the University of Maryland School of Medicine
Formed in 1996 as a partnership between the State of Maryland, the City of Baltimore, the University System of Maryland and the University of Maryland Medical System, IHV is an in...
Kineta is a Seattle-based privately held biotechnology company specializing in clinical advancement of novel drug candidates derived from leading edge scientific research. Our wor...
TRANSGENE is a leading integrated gene therapy company, dedicated to the discovery and development of gene delivery technologies and gene therapy products for the treatment of acquired and inherited d...
Zalicus focuses its internal drug development efforts on pain and immuno-inflammatory diseases. Our pipeline for pain includes Exalgo⢠(hydromorphone HCl) extended-release ta...
The International Society for Interferon and Cytokine Research (ISICR), based in Bethesda, Md., is a non-profit organization devoted to interferon, cytokine and chemokine r...
Profectus BioSciences, Inc. is a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases with a goal of reducing morbidity and mo...
Nexera Medical Inc. is headquartered in Fort Lauderdale, Florida. The company is engaged in the development, manufacturing, and distribution of antimicrobial respirator and surgic...
Break Media is a leading creator, publisher, and distributor of digital entertainment content including video, editorial, and games. The company's properties include the largest h...
Engage With Grace is a non-profit, viral movement designed to help get the conversation about the end-of-life experience started. The movement is built around The One Sl...
PaxVax is a privately held company established in 2007 to develop and commercialize innovative and socially responsible vaccines against infectious diseases. PaxVax has a clinical...
Clinical Trials
Cohort Study for Patients Using Fuzeon (Enfuvirtide)
The Radata-Fuzeon cohort is an observational cohort study to gain a better understanding of Fuzeon (Enfuvirtide) in daily clinical practice. Patients planned to take this drug in a new ant...
This pilot study is to assess whether using CytoGam® in combination with ganciclovir is more effective in reducing the CMV viral load over time, as compared to standard treatment with IV...
Genotype 1 hepatitis C virus (HCV) patients who did not respond (did not lose virus during treatment) or relapsed (virus went away on treatment but came back after treatment was stopped) a...
Induction-Maintenance With Atazanavir in HIV Naïve Patients (The INDUMA Study)
The purpose of this study is to compare the proportion of subjects with HIV-1 RNA viral load < 50 c/mL through Week 48 of the Maintenance Phase among HIV-infected subjects with an initial...
Hypothesis Nevirapine resistance developed in women and infants in the HIVNET 006 and 012 cohorts as a consequence of use of an agent with a long t½ as monotherapy in individuals with hi...
The purpose of the study is to compare the effectiveness of two treatment regimens in clearing the Hepatitis C Virus in patients infected with Hepatitis C genotype 1. The study aims to de...
ANTEAB: a Study of Early Antibiotherapy in the ICU Management of Acute Exacerbations of COPD
Intensive Care Unit (ICU) admission for acute exacerbation of chronic obstructive lung disease (COLD) is a major cause of morbidity and mortality in such patients. Although bacterial of mo...
Evaluation of the Safety of a Polyvalent Virus in Healthy Adults
This is a research study to evaluate the safety of a vaccine to protect people from HIV infection. Human Immunodeficiency Virus (HIV) is the cause of AIDS (Acquired Immune Deficiency Syndr...
Betaferon/ Betaseron (Interferon Beta-1b) in Patients With Chronic Viral Cardiomyopathy
Chronic viral cardiomyopathy is a disease where the cardiac muscle is attacked by a virus and this may result in a reduction in the output of the heart (pump function) thereby causing comp...
Induction of Cytokines in Human Monocytes by SARS-CoV in Adults and Children
Severe acute respiratory syndrome (SARS) is a new emerging infectious disease. Its pathogen is a newly discovered coronavirus (SARS-CoV). The clinical course can be classified to 3 stages:...
Videos
Conjunctivitis, pink eye, virus or bacteria, eye infection - A State of Sight #35
Isaac Porter, MD explains conjunctivitis (pink eye) in this episode of A State of Sight. The conjunctiva is the thin layer of tissue that covers the eye. Whe...
Medical and Biotech [MESH] Definitions
Semaphorins
A family of proteins that mediate axonal guidance. Semaphorins act as repulsive cues for neuronal GROWTH CONES and bind to receptors on their filopodia. At least 20 different molecules have been described and divided into eight classes based on domain organization and species of origin. Classes 1 and 2 are invertebrate, classes 3-7 are vertebrate, and class V are viral. Semaphorins may be secreted (classes 2, 3, and V), transmembrane (classes 1, 4, 5, and 6), or membrane-anchored (class 7). All semaphorins possess a common 500-amino acid extracellular domain which is critical for receptor binding and specificity, and is also found in plexins and scatter factor receptors. Their C termini are class-specific and may contain additional sequence motifs.
Severe Acute Respiratory Syndrome
A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent.
Nipah Virus
A species of HENIPAVIRUS, closely related to HENDRA VIRUS, which emerged in Peninsular Malaysia in 1998. It causes a severe febrile VIRAL ENCEPHALITIS in humans and also encephalitis and RESPIRATORY TRACT INFECTIONS in pigs. Fruit bats (PTEROPUS) are the natural host.
Intranuclear Inclusion Bodies
Circumscribed masses of foreign or metabolically inactive materials, within the CELL NUCLEUS. Some are VIRAL INCLUSION BODIES.
Mycoplasma Conjunctivae
A species of gram-negative bacteria causing CONJUNCTIVITIS and KERATOCONJUNCTIVITIS in SHEEP and GOATS.
