Vitamin D Toxicity - Biotech, Pharma and Life Science Channel
PubMed Articles
Accelerated hypofractionation (HF) using larger dose per fraction, delivered in fewer fractions over a shorter overall treatment time, is presently a consistent possibility for adjuvant whole breast r...
The aim of the study is to evaluate the efficacy and safety of a three-drug chemotherapy regimen including gemcitabine, carboplatin, and paclitaxel as induction therapy in clinical stage III non-small...
Recent phase-III trials show that platinum-based chemotherapy (PBCT) for patients with advanced non-small cell lung cancer and poor performance status (PS) improves survival without increasing toxicit...
To investigate the effects of a low bisphenol A (BPA) concentration on male reproduction, adult rats were administered a concentration of BPA that was less than the no observable adverse effect level...
The vitamin D analog ED-71 (eldecalcitol) has been shown to be superior to calcitriol and its precursor alfacalcidol in maintaining or increasing bone mass in women and animal models with osteoporosis...
Fluorescence 'turn-on' sensor for F(-) derived from vitamin B6 cofactor.
A novel vitamin B6 Schiff base analog () was synthesized by combining vitamin B6 cofactor pyridoxal with 2-aminophenol. Receptor displays a color change detectable by the naked-eye from yellow to red...
Bone health and aldosterone excess.
A picture of hyperparathyroidism secondary to increased urinary calcium excretion was found in 116 patients with primary aldosteronism (PA), compared with 110 essential hypertensives. After medical or...
Angiotensin II antagonists - an assessment of their acute toxicity.
Objective. In Germany, increasing prescription rates of angiotensin II antagonists resulted in rising enquiries to Poisons Information Centres (PICs) during the last decade. Therefore, we aimed to ass...
The goal of oxygen therapy is to deliver sufficient oxygen to the tissues while minimizing oxygen toxicity and oxidative stress. It remains uncertain what values of arterial oxygen saturations achieve...
Analogues of the tripyrrolic natural product prodigiosin bearing an additional methyl and a carbonyl group at the C-ring were synthesised and evaluated. In vitro anticancer activity screening (NCI) an...
News Articles
Duchesnay introduces Diclegis in US market
Duchesnay USA has announced the availability of Diclegis, a composition of 10mg doxylamine succinate and 10mg pyridoxine hydrochloride (vitamin B6), in US pharmacies.
WASHINGTON, May 23, 2013 /PRNewswire-USNewswire/ -- Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during in...
Fighting Ovarian Cancer With Gold Nanoparticles
Positively charged gold nanoparticles are usually toxic to cells, but cancer cells somehow manage to avoid nanoparticle toxicity. Mayo Clinic researchers found out why and determined how to make the n...
Improved chemo regimen for childhood leukemia may offer high survival, no added heart toxicity
(American Society of Hematology) Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may...
Vitamin C Kills Mycobacterium tuberculosis
TB bacteria, including drug-resistant strains, are ultrasensitive to the vitamin C prooxidant effect. Medscape Medical News
Vitamin C may not treat gout: study
NEW YORK (Reuters Health) - Daily vitamin C supplements don't lower uric acid as much as drugs used to treat high levels of the acid that's responsible for gout, says a new study from New Zealand.
The nine months during a pregnancy and the months that follow during breast-feeding can place a number of physical, physiological and metabolic demands on women. With our nutritional and chemical ba...
Vitamin C May Be Key to New TB Treatments
(MedPage Today) -- In a serendipitous discovery, researchers said they killed cultured strains of drug-resistant tuberculosis bacteria with vitamin C.
Smart Sun Choices With Ascenta Skin: Just one teaspoon a day helps to keep UV damage away!
NEW YORK, May 22, 2013 /PRNewswire/ -- Memorial Day weekend marks the unofficial start of summer and the beginning of extra time spent basking in the sun. While a little dose of Vitamin D i...
Lean On Life Supports New Research Encouraging a Healthy Mix of Dried Fruit
Lean On Life, a leading healthy lifestyle website with the latest on weight loss, nutrition, and fitness is supporting the incorporation of dried fruit as part of a healthy diet. Toronto, ON (PRWEB) M...
Companies
BuckPower Deer Velvet is imported from New Zealand and marketed by TCCD International, a South Florida manufacturer of natural products. Specially formulated with enzymes, 100% na...
MRI is the leader in innovative sports nutrition products with a focus on combining science-based, unique active ingredients with highly efficient nutrient-delivery technologies e...
HemoGenix® is a privately-held Contract Research Service and Assay Development Laboratory based in Colorado Springs, Colorado. Specializing in predictive in vitro stem cell tox...
Headquartered in Ft. Lauderdale, FL, LTS Nutraceuticals, Inc. develops, manufactures, markets and distributes an expanding line of unique, high-quality vitamins, vitamin boosters,...
Liquid Nutrition Group Inc. (LNGI) (TSX-V: LQD.V and LQD.WT) is a functional beverage, vitamin and supplement store brand committed to bringing healthy and delicious eating to com...
Cellectis stem cells, is a business unit within the Cellectis group and is a global leader in stem cell technology. Cellectis stem cells, created in November 2011 from Cellartis A...
Founded in 2000, The BlenderBottle Company is a privately held manufacturer of premium and innovative products that help simplify everyday life. The companyâs patented and be...
PURE Bioscience develops and markets technology-based bioscience products that provide solutions to numerous global health challenges, including Staph (MRSA). PURE's proprietary h...
Absorption Systems, founded in 1996, assists pharmaceutical, biotechnology and medical device companies in identifying and overcoming ADMET (Absorption, Distribution, Metabolism,...
Pro-Pharmaceuticals, OTCBB: PRWP, is the leader in the field of Galectin therapeutics and is engaged in the discovery, development and commercialization of therapeutics that targe...
Clinical Trials
This randomized, multicenter, open label study will evaluate the safety and efficacy of RO5083945 in combination with FOLFIRI as compared to FOLFIRI plus cetuximab or FOLFIRI alone as seco...
Mesenchymal Stromal Cells (MSCs) for the Treatment of Graft Versus Host Disease (GVHD)
This is a bicentric, prospective, non randomized study. Pediatric and adult patients will be treated. Rationale: MSC have shown promising effects by reversal of severe therapy-resistant a...
A Study of Epirubicin With Estramustine Phosphate and Celecoxib for the Treatment of Prostate Cancer
The purpose of this clinical trial is to find out the effect of epirubicin with estramustine phosphate and celecoxib on PSA and objective response in patients with hormone resistant prosta...
XELOX (Capecitabine and Oxaliplatin) is an effective and convenient regimen for patients with metastatic colorectal cancer. Chronomodulated therapy may reduce toxicity. Patients will be ra...
Trial of the Impact of Vitamin A on Maternal Mortality
Main objectives: To evaluate the impact of weekly vitamin A supplementation (VAS) to women of reproductive age (15-45 years) on maternal mortality in rural Ghana, and to compare this with...
Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment
Number of elderly people over 70 is increasing in France. In 2002, in the south-west, 273,741 of them were over 75 years, i.e. 9.2% of Aquitaine population. Incidence of cancer in this old...
Cetuximab, Capecitabine, Oxaliplatin and Bevacizumab in Advanced Colorectal Cancer
This is a study to assess the efficacy and safety of the addition of cetuximab to the combined regimen of capecitabine, oxaliplatin and bevacizumab in patients with previously untreated ad...
Lactate Metabolism Study in HIV Infected Persons
Lactic acidosis is a potentially life-threatening disease associated with the treatment of chronic HIV infection. Although acidosis is rare, hyperlactatemia is common and may have long ter...
Patients with acute lymphoblastic leukaemia or very aggressive lymphoma and documented isolated CNS relapse or CNS relapse combined with other relapse sites should receive therapy with int...
Single-Dose Postpartum Vitamin A Supplementation of Mothers and Neonates
The ZVITAMBO PROJECT is testing whether giving mothers and infants a single large dose of vitamin A during the immediate post partum period will reduce: 1. Infant Mortality Can oral adm...
Videos
Treatment & Toxicity -- Benefits and dangers of supplementing with Vitamin D. Dr Reinhold Vieth
Dr. Reinhold Vieth is Professor in the Department of Nutritional Sciences, and the Department of Laboratory Medicine and Pathology, University of Toronto. He...
Medical and Biotech [MESH] Definitions
Iron-regulatory Proteins
Proteins that regulate cellular and organismal iron homeostasis. They play an important biological role by maintaining iron levels that are adequate for metabolic need, but below the toxicity threshold.
Solanum Glaucophyllum
A plant species of the genus SOLANUM, family SOLANACEAE that causes CALCINOSIS in grazing livestock due to high levels of 1a,25-dihydroxy vitamin D3 (CALCITRIOL).
Toxicity Tests, Chronic
Experiments designed to determine the potential toxic effects of a long-term exposure to a chemical or chemicals.
Herb-drug Interactions
The effect of herbs, other PLANTS, or PLANT EXTRACTS on the activity, metabolism, or toxicity of drugs.
Toxicogenetics
The study of existing genetic knowledge, and the generation of new genetic data, to understand and thus avoid DRUG TOXICITY and adverse effects from toxic substances from the environment.
