Vocal Cord Paralysis - Biotech, Pharma and Life Science Channel

09:10 EDT 1st April 2015 | BioPortfolio

PubMed Articles [1566 Associated PubMed Articles listed on BioPortfolio]

Induction of long-term potentiation and long-term depression is cell-type specific in the spinal cord.

The underlying mechanism of chronic pain is believed to be changes in excitability in spinal dorsal horn (DH) neurons that respond abnormally to peripheral input. Increased excitability in pain transm...

Selective keratinocyte stimulation is sufficient to evoke nociception in mice.

The skin epidermis is densely innervated by peripheral sensory nerve endings. Nociceptive neurons, whose terminals are in close contact with epidermal keratinocytes, can be activated directly by noxio...

Pseudoloma neurophilia: A Retrospective and Descriptive Study of Nervous System and Muscle Infections, with New Implications for Pathogenesis and Behavioral Phenotypes.

Pseudoloma neurophilia is a microsporidium of zebrafish (Danio rerio) that preferentially infects neural tissue. It is one of the most common pathogens of zebrafish in research laboratories based on d...

Integration of Shallow Gradients of Shh and Netrin-1 Guides Commissural Axons.

During nervous system development, gradients of Sonic Hedgehog (Shh) and Netrin-1 attract growth cones of commissural axons toward the floor plate of the embryonic spinal cord. Mice defective for eith...

Spinal extradural arachnoid cyst presenting as recurrent abdominal pain.

Spinal arachnoid cysts are an infrequently reported cause of abdominal pain in children. In this report, we describe the unusual case of an extradural arachnoid cyst presenting as recurrent abdominal ...

Observation and partial targeted surgery in the management of tympano-jugular paraganglioma: a contribution to the multioptional treatment.

The objective of this study was to assess the value of a limited tumor excision in tympano-jugular paragangliomas treated with observation with the goal of preventing, or repairing, a neural (VII cran...

Expression of the Immunoglobulin Superfamily Cell Adhesion Molecules in the Developing Spinal Cord and Dorsal Root Ganglion.

Cell adhesion molecules belonging to the immunoglobulin superfamily (IgSF) control synaptic specificity through hetero- or homophilic interactions in different regions of the nervous system. In the de...

Activation of Mu or Delta Opioid Receptors in the Lumbosacral Spinal Cord Is Essential for Ejaculatory Reflexes in Male Rats.

Ejaculation is controlled by a spinal ejaculation generator located in the lumbosacral spinal cord, consisting in male rats of lumbar spinothalamic (LSt) cells and their inter-spinal projections to au...

Network Analyses Reveal Novel Aspects of ALS Pathogenesis.

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective loss of motor neurons, muscle atrophy and paralysis. Mutations in the human VAMP-associated protein ...

Novel Pathway for Hypoxia-Induced Proliferation and Migration in Human Mesenchymal Stem Cells: Involvement of HIF-1α, FASN, and mTORC1.

The control of stem cells by oxygen signaling is an important way to improve various stem cell physiological functions and metabolic nutrient alteration. Lipid metabolism alteration via hypoxia is tho...

News Articles [759 Associated News Articles listed on BioPortfolio]

InVivo Therapeutics Announces New Clinical Trial Site for Neuro-Spinal Scaffold

InVivo Therapeutics Holdings Corp. (NVIV) today announced that UC Davis Medical Center in Sacramento, CA has been added as a clinical site in the company’s ongoing IDE pilot st...

Researchers and supercomputers to help create a standard 3D neuron model

Before scientists can unlock the secrets of the human brain, they must fully understand neurons—the cells of our brain, spinal cord and overall nervous system. Thousands of detailed neuron images, f...

Cruz News Wasn't The Real Obamacare Story in March

National media reported plenty on Obamacare recently. Mostly, they were talking about the first declared 2016 Republican presidential candidate, Sen. Ted Cruz (R-Texas), disclosing that he would sign...

Cruz News Was't The Real Obamacare Story in March

National media reported plenty on Obamacare recently. Mostly, they were talking about the first declared 2016 Republican presidential candidate, Sen. Ted Cruz (R-Texas), disclosing that he would sign...

Pain and Itch Neurons Found

Inhibitory nerve cells in the spinal cord stop the transmission of pain and itch signals in mice.

NeuroRecovery Training Institute Faculty Members To Present at 2015 ISCoS and ASIA Joint Scientific Meeting

Two of NeuroRTI’s Pediatric Faculty Members Will Present on the Pediatric Neuromuscular Recovery Scale at This Year’s Conference Louisville, KY (PRWEB) March 31, 2015 NeuroRecovery Training Insti...

Analysis of the Global Stem Cell Market

LONDON, March 31, 2015 /PRNewswire/ -- This study investigates the global stem cell market for the period 2013 to 2018. The geographic regions covered in the study are the North America, Europe and AP...

An unknown enemy: Drugs sought against EV-68 as paralysis link is explored

Scientists one step closer to finding how to repair damaged nerve cells

A team of researchers has uncovered a new kind of synergy in the development of the nervous system, which explains an important mechanism required for neural circuits to form properly. This breakthrou...

Scientists get one step closer to finding how to repair damaged nerve cells

A team of researchers at the IRCM led by Frédéric Charron, PhD, in collaboration with bioengineers at McGill University, uncovered a new kind of synergy in the development of the nervous system, whi...

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Companies [42 Associated Companies listed on BioPortfolio]

Ty Louis Campbell Foundation

Founded in September 2012, The Ty Louis Campbell (TLC) Foundation is a nonprofit organization that funds innovative research specifically geared toward the treatment of the deadli...

Paralyzed Veterans of America 

Paralyzed Veterans of America is the only congressionally chartered veterans service organization dedicated solely for the benefit and representation of veterans withÂ...

The Sloan Firm

The Sloan Firm was established in 1980 and has offices in Longview and Houston, Texas. The Sloan Firm has an impressive track record in negotiations and litigation in its primary ...

Asterias Biotherapeutics, Inc.

Asterias Biotherapeutics is a subsidiary of BioTime, Inc., whose mission is to acquire and develop best in class cell therapy product candidates. Our first acquisition was the ste...

Mediware Information Systems, Inc.

Mediware delivers software systems that improve efficiencies and address safety concerns, enabling healthcare organizations to improve care processes while decreasing costs. Core ...

CDH Proton Center

CDH Proton Center, A ProCure Center, Warrenville, Ill., is one of a handful of facilities in the country that offer proton therapy, an advanced form of radiation to treat cancer. ...

Be The Match

For people with life-threatening blood cancers—like leukemia and lymphoma—or other diseases, a cure exists. Be The Match connects patients with their donor match for a l...

Cryopraxis

Launched in 2001, Cryopraxis® is Brazil's pioneer company dedicated to long term stem cell banking. Cryopraxis® is also Brazil's leader in research and development with stem...

Remedy Pharmaceuticals, Inc.

Remedy Pharmaceuticals, Inc. is a clinical stage pharmaceutical company focused on the development and commercialization of small molecule drugs for acute central nervous system d...

HemoGenix, Inc.

HemoGenix® is a privately-held Contract Research Service and Assay Development Laboratory based in Colorado Springs, Colorado. Specializing in predictive in vitro stem cell tox...

Clinical Trials [589 Associated Clinical Trials listed on BioPortfolio]

Safety and Efficiency of Umbilical Cord-derived Mesenchymal Stem Cells(UC-MSC) in Patients With Alzheimer's Disease

The primary purpose of this study is to evaluate the safety and the tolerability of UC-MSC (Human Umbilical Cord-Derived Mesenchymal Stem Cell) .This study is also to investigate the effic...

VentFirst Pilot: Ventilating Preterm Infants During Delayed Cord Clamping

Delayed clamping of the umbilical cord (DCC) has been shown to have some benefits for preterm infants. Initiation of breathing before cord clamping is also thought to be beneficial. Since...

Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies

The goal of this clinical research study is to learn if thiotepa, busulfan, and clofarabine, when given before an allogeneic (bone marrow , blood, or cord blood cells) or haploidentical (b...

Autologous Umbilical Cord Blood Infusion for Children With Autism Spectrum Disorder (ASD)

This study is a prospective phase 1 single-center trial designed to determine the safety of a single intravenous infusion of autologous umbilical cord blood in children with Autism Spectru...

Use of an Oral Beta-2 Agonist in Persons With Spinal Cord Injury

The primary purpose of this study is to determine the effect of administration of the oral beta-2 adrenergic agonist, albuterol, on respiratory muscle strength in individuals with cervical...

Dose Escalation Study of AST-OPC1 in Spinal Cord Injury

The purpose of this study is to evaluate the safety of 3 sequential escalating doses of AST-OPC1 administered at a single time-point between 14 and 30 days post injury, inclusively, to sub...

Riluzole in Spinal Cord Injury Study

The aim of this study is to evaluate efficacy and safety of riluzole in the treatment of patients with acute SCI. The primary objective is to evaluate the superiority of riluzole, at a do...

Cardiovascular Disease Study

Coronary heart disease (CHD) is a leading cause of death in the spinal cord injured (SCI) population, occurring at younger ages than in the able-bodied population. Conventional risk facto...

Spinal Cord Stimulation (SCS) Therapy Study

The purpose of this study is to evaluate the effect of different spinal cord stimulation settings in the treatment of leg pain. Subjects will receive a randomized order of four different p...

Evaluation of Autologous Mesenchymal Stem Cell Transplantation in Chronic Spinal Cord Injury: a Pilot Study

The purpose of this study is to analyze the safety and efficacy of mesenchymal stem cell transplantation through percutaneous injection in patients with chronic spinal cord injury.

Medical and Biotech [MESH] Definitions

Congenital or acquired paralysis of one or both VOCAL CORDS. This condition is caused by defects in the CENTRAL NERVOUS SYSTEM, the VAGUS NERVE and branches of LARYNGEAL NERVES. Common symptoms are VOICE DISORDERS including HOARSENESS or APHONIA.

A pair of cone-shaped elastic mucous membrane projecting from the laryngeal wall and forming a narrow slit between them. Each contains a thickened free edge (vocal ligament) extending from the THYROID CARTILAGE to the ARYTENOID CARTILAGE, and a VOCAL MUSCLE that shortens or relaxes the vocal cord to control sound production.

INFARCTION of the dorsolateral aspect of MEDULLA OBLONGATA in the BRAIN STEM. It is caused by occlusion of the VERTEBRAL ARTERY and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801)

A group of congenital malformations involving the brainstem, cerebellum, upper spinal cord, and surrounding bony structures. Type II is the most common, and features compression of the medulla and cerebellar tonsils into the upper cervical spinal canal and an associated MENINGOMYELOCELE. Type I features similar, but less severe malformations and is without an associated meningomyelocele. Type III has the features of type II with an additional herniation of the entire cerebellum through the bony defect involving the foramen magnum, forming an ENCEPHALOCELE. Type IV is a form a cerebellar hypoplasia. Clinical manifestations of types I-III include TORTICOLLIS; opisthotonus; HEADACHE; VERTIGO; VOCAL CORD PARALYSIS; APNEA; NYSTAGMUS, CONGENITAL; swallowing difficulties; and ATAXIA. (From Menkes, Textbook of Child Neurology, 5th ed, p261; Davis, Textbook of Neuropathology, 2nd ed, pp236-46)

The process of producing vocal sounds by means of VOCAL CORDS vibrating in an expiratory blast of air.

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