Vocal Cord Paralysis - Biotech, Pharma and Life Science Channel

02:50 EDT 1st November 2014 | BioPortfolio

PubMed Articles [1625 Associated PubMed Articles listed on BioPortfolio]

Patterns of variance in /s/ during normal and glossectomy speech.

The production of speech includes considerable variability in speech gestures despite our perception of very repeatable sounds. Variability is seen in vocal tract shapes and tongue contours when diffe...

The barriers, benefits and facilitators of leisure time physical activity among people with spinal cord injury: a meta-synthesis of qualitative findings.

Physical activity (PA) can have a positive impact upon health and well-being for people with spinal cord injury (SCI). Despite these benefits, people with SCI are within the most physically inactive s...

Skeletal tissue engineering using mesenchymal or embryonic stem cells: clinical and experimental data.

Introduction: Mesenchymal stem cells (MSCs) can be obtained from a wide variety of tissues for bone tissue engineering such as bone marrow, adipose, birth-associated, peripheral blood, periosteum, den...

Language ENvironment Analysis Language and Autism Screen and the Child Development Inventory Social Subscale as a Possible Autism Screen for Children Who Are Deaf or Hard of Hearing.

The Language ENvironment Analysis Language and Autism Screen (LLAS) is an automated vocal production analysis that has been shown to be a valid screener for autism in hearing children between the ages...

Increased Total Serum Random Cortisol Levels Predict Mortality in Critically Ill Trauma Patients.

Dysfunction in the hypothalamopituitary adrenal axis is thought to exist; however, there continues to be controversy about what level of serum cortisol corresponds to adrenal insufficiency. Few studie...

An innovative repair for a re-recurrence of an incarcerated inguinal hernia.

A patient presented with a recurrent incarcerated inguinoscrotal hernia requiring urgent surgery. The defect was through the gap in the mesh left originally for the cord structures. As a result, a mod...

Evaluation of ultrasmall superparamagnetic iron oxide contrast agent labeling of equine cord blood and bone marrow mesenchymal stromal cells.

Objective-To evaluate the efficacy and effects of labeling equine umbilical cord blood (UCB)- and bone marrow (BM)-derived multipotent mesenchymal stromal cells (MSCs) with an ultrasmall superparamagn...

One-Unit versus Two-Unit Cord-Blood Transplantation for Hematologic Cancers.

Background Umbilical-cord blood has been used as the source of hematopoietic stem cells in an estimated 30,000 transplants. The limited number of hematopoietic cells in a single cord-blood unit preven...

Motherese by Eye and Ear: Infants Perceive Visual Prosody in Point-Line Displays of Talking Heads.

Infant-directed (ID) speech provides exaggerated auditory and visual prosodic cues. Here we investigated if infants were sensitive to the match between the auditory and visual correlates of ID speech ...

Acute inhibition of a cortical motor area impairs vocal control in singing zebra finches.

Genetically targeted approaches that permit acute and reversible manipulation of neuronal circuit activity have enabled an unprecedented understanding of how discrete neuronal circuits control animal ...

News Articles [795 Associated News Articles listed on BioPortfolio]

The ALS Association Triples Spending on Research Thanks to Ice Bucket Donations

WASHINGTON, Oct. 31, 2014 /PRNewswire-USNewswire/ -- The ALS Association announced on Thursday that the Board of Trustees has met and developed a long-term strategy for leveraging the Ice Bucket ...

With new spinal cord stimulator, Army veteran is finally free of pain

Good news: Craig Hoffman separated his shoulder. Wait. Why is that good news? Let's back up.

Digital Therapist: Computer program analyzes speech, mental health

A program that analyzes your speech and uses it to gain information about your mental health could soon be feasible, thanks in part to new research showing that certain vocal features change as patien...

Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells – motor neurons – in the brain, brainstem and spinal cord, leading to progressive ...

Rehabilitation Institute of Chicago Celebrates Patient Perseverance with Sixth-Annual SkyRise Chicago

CHICAGO, Oct. 30, 2014 /PRNewswire/ -- When Elizabeth Bandolik was 9 years old, she was rushed into emergency brain surgery for a ruptured cerebral aneurysm. Surgery was followed by a coma that lasted...

HEMACORD®, the First FDA-Licensed Stem Cell Product, Wins Prix Galien USA "Best Biotechnology Product" Award

NEW YORK, Oct. 30, 2014 /PRNewswire-USNewswire/ -- The New York Blood Center's Milstein National Cord Blood Program (NCBP) is pleased to announce that HEMACORD®, the first FDA-licensed hematopoie...

Reconstruction of patterned piece of spinal cord in 3D culture

The central nervous system in vertebrates develops from the neural tube, which is the basis for the differentiation in spinal cord and brain. Researchers have demonstrated for the first time the in vi...

Reconstruction of a patterned piece of spinal cord in 3D culture

The central nervous system in vertebrates develops from the neural tube, which is the basis for the differentiation in spinal cord and brain. Professor Elly Tanaka and her research group at the DFG Re...

New standard of care for pediatric AML patients who receive umbilical cord transplants

A new standard of care for children facing acute myeloid leukemia (AML) may be clear, following a multi-year study published in the latest edition of the New England Journal of Medicine.

Reconstruction of a patterned piece of spinal cord in 3-D culture

(Technische Universität Dresden) The central nervous system in vertebrates develops from the neural tube, which is the basis for the differentiation in spinal cord and brain.

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Companies [39 Associated Companies listed on BioPortfolio]

Asterias Biotherapeutics, Inc.

Asterias Biotherapeutics is a subsidiary of BioTime, Inc., whose mission is to acquire and develop best in class cell therapy product candidates. Our first acquisition was the ste...

Mediware Information Systems, Inc.

Mediware delivers software systems that improve efficiencies and address safety concerns, enabling healthcare organizations to improve care processes while decreasing costs. Core ...

CDH Proton Center

CDH Proton Center, A ProCure Center, Warrenville, Ill., is one of a handful of facilities in the country that offer proton therapy, an advanced form of radiation to treat cancer. ...

Be The Match

For people with life-threatening blood cancers—like leukemia and lymphoma—or other diseases, a cure exists. Be The Match connects patients with their donor match for a l...

Cryopraxis

Launched in 2001, Cryopraxis® is Brazil's pioneer company dedicated to long term stem cell banking. Cryopraxis® is also Brazil's leader in research and development with stem...

Remedy Pharmaceuticals, Inc.

Remedy Pharmaceuticals, Inc. is a clinical stage pharmaceutical company focused on the development and commercialization of small molecule drugs for acute central nervous system d...

HemoGenix, Inc.

HemoGenix® is a privately-held Contract Research Service and Assay Development Laboratory based in Colorado Springs, Colorado. Specializing in predictive in vitro stem cell tox...

AuxoCell Laboratories, Inc.

AuxoCell Laboratories, Inc. (AuxoCell) is a leading stem cell therapeutic and regenerative medicine company located in Massachusetts. AuxoCell's primary research focus is to devel...

GeneCell International

GeneCell International, LLC is a trusted provider of collection, processing and storage of umbilical cord blood from which stem cells can be extracted to treat a variety of diseas...

Detroit Shriners

The Shriners is a fraternity based on fun, fellowship and the principles of brotherly love, truth and relief. We promote strong family values, fraternal and social interact...

Clinical Trials [559 Associated Clinical Trials listed on BioPortfolio]

Treatment of SCID Due to ADA Deficiency With Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells After Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector

This is a clinical gene transfer study that aims to verify the safety and efficacy of the use of the EFS-ADA lentiviral vector to introduce the human adenosine deaminase (ADA) gene into th...

Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative Regimen

In this study, participants with high-risk hematologic malignancies undergoing hematopoietic cell transplantation (HCT), who do not have a suitable human leukocyte antigen (HLA)-matched re...

High Dose Gefitinib for the Treatment of Carcinomatous Meningitis in Adult Patients With Non-Small Cell Lung Cancer and Known or Suspected EGFR Mutations

The primary purposes of this study are to find out if using high doses of the drug Gefitinib (Iressa) as a way to treat patients with non-small cell lung cancer that has spread to the cove...

Evaluation of Wire Electrodes to Activate the Expiratory Muscles to Restore Cough

Respiratory infections, such as pneumonia and bronchitis, occur frequently in the spinal cord injured population, due to paralysis of the muscles responsible for coughing. Using spinal cor...

Natural Killer (NK) Cells in Cord Blood Transplantation

The goal of this clinical research study is to learn if giving cells called natural killer (NK) cells after receiving fludarabine, melphalan, lenalidomide, and a UCB transplant can improve...

Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury

As a first-in-class (Central Pattern Generator or CPG activator) approach, this tritherapy candidate called SPINALON has been identified and is currently under development for its capacity...

Phase II Clinical Trial of NPB-01 in Patients With Anti-aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder Not Provided Adequate Effect of Therapy to Steroids Plus Therapy.

Patients diagnosed with anti-aquaporin 4 antibody positive Neuromyelitis Optica spectrum disorder were confirmed based on diagnostic criteria. Patients who meet all inclusion criteria and ...

A Randomised Pilot Study to Assess Differences in Stimulation Induced Paresthesia Between 2 Spinal Cord Stimulation Systems

12-SMI-2014 is a post-market, randomised, pilot study to identify and rate differences in patient experiences with two different types of Spinal Cord Stimulator devices which are routinely...

Autologous Bone Marrow Cell Transplantation in Persons With Acute Spinal Cord Injury- An Indian Pilot Study.

Pilot study on 7 subjects in each group (total 21 subjects) to establish the safety and feasibility of autologous bone marrow cell transplantation in case of acute complete spinal cord in...

Evaluation of Lyme Disease: Clinical, Microbiological and Immunological Characteristics

This study will determine whether patients who have been infected with the Lyme bacteria, Borrelia burgdorferi, and treated with antibiotics still have the bacteria alive inside them and w...

Medical and Biotech [MESH] Definitions

Congenital or acquired paralysis of one or both VOCAL CORDS. This condition is caused by defects in the CENTRAL NERVOUS SYSTEM, the VAGUS NERVE and branches of LARYNGEAL NERVES. Common symptoms are VOICE DISORDERS including HOARSENESS or APHONIA.

A pair of cone-shaped elastic mucous membrane projecting from the laryngeal wall and forming a narrow slit between them. Each contains a thickened free edge (vocal ligament) extending from the THYROID CARTILAGE to the ARYTENOID CARTILAGE, and a VOCAL MUSCLE that shortens or relaxes the vocal cord to control sound production.

INFARCTION of the dorsolateral aspect of MEDULLA OBLONGATA in the BRAIN STEM. It is caused by occlusion of the VERTEBRAL ARTERY and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801)

A group of congenital malformations involving the brainstem, cerebellum, upper spinal cord, and surrounding bony structures. Type II is the most common, and features compression of the medulla and cerebellar tonsils into the upper cervical spinal canal and an associated MENINGOMYELOCELE. Type I features similar, but less severe malformations and is without an associated meningomyelocele. Type III has the features of type II with an additional herniation of the entire cerebellum through the bony defect involving the foramen magnum, forming an ENCEPHALOCELE. Type IV is a form a cerebellar hypoplasia. Clinical manifestations of types I-III include TORTICOLLIS; opisthotonus; HEADACHE; VERTIGO; VOCAL CORD PARALYSIS; APNEA; NYSTAGMUS, CONGENITAL; swallowing difficulties; and ATAXIA. (From Menkes, Textbook of Child Neurology, 5th ed, p261; Davis, Textbook of Neuropathology, 2nd ed, pp236-46)

The process of producing vocal sounds by means of VOCAL CORDS vibrating in an expiratory blast of air.

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