Weakness - Biotech, Pharma and Life Science Channel
PubMed Articles
This retrospective analysis of hip fracture patients with and without muscle atrophy/weakness (MAW) revealed that those with MAW had significantly higher healthcare utilization and costs compared with...
A smart-card based authentication scheme for telecare medicine information systems enables patients, doctors, nurses, health visitors and the medicine information systems to establish a secure communi...
Carbene formation in ionic liquids: spontaneous, induced, or prohibited?
We present a theoretical study of carbene formation from the 1-ethyl-3-methylimidazolium acetate ionic liquid in the absence and presence of CO2 in gas and liquid phase. Although CO2 physisorption con...
Clinical and Molecular Characterization of Mcardle's Disease in Brazilian Patients.
McArdle's disease, a glycogen storage disease type V, is caused by a deficiency of the enzyme myophosphorylase, encoded by the PYGM gene. Worldwide distribution of mutations has revealed interesting d...
Fatigue related to radiotherapy for breast and/or gynaecological cancer: a systematic review.
AIMS AND OBJECTIVES: To assess the profile, evaluation criteria and fatigue treatment. BACKGROUND: Fatigue, characterised by tiredness, weakness or lack of energy, involves physical, cognitive and emo...
Clinical Trials Using Antisense Oligonucleotides in Duchenne Muscular Dystrophy.
Abstract Duchenne muscular dystrophy (DMD) is a severe muscle wasting disorder caused by mutations in the DMD gene, affecting 1 in 3500 newborn males. Complete loss of muscle dystrophin protein causes...
Recent developments in the treatment of Duchenne muscular dystrophy and spinal muscular atrophy.
Pediatric neuromuscular disorders comprise a large variety of disorders that can be classified based on their neuroanatomical localization, patterns of weakness, and laboratory test results. Over the...
At our institution surgical correction of symptomatic flat foot deformities in children has been guided by a paradigm in which radiographs and pedobarography are used in the assessment of outcome foll...
Teaching NeuroImages: Longitudinally extensive transverse myelitis in neuro-Behcet disease.
A 25-year-old man presented with subacute spastic paraparesis. He reported 2 previous episodes of spastic paraparesis with partial recovery. Recurrent oral and genital ulceration, pustular skin erupti...
EFNS review on the role of muscle biopsy in the investigation of myalgia.
BACKGROUND: Myalgia, defined as any pain perceived in muscle, is very common in the general population and a frequent cause for referral to neurologists, rheumatologists and internists in general. It...
News Articles
Pressured by weakness and anxiety ends a leg lower
The RegMed stocks mirrored the market. Most were down and a few were taken lower and a couple up just before the close. On the whole … a bit like yesterday when I compared … “Gravity and the for...
Trius Patent Intrigues Investors, And Perhaps Cubist Pharmaceuticals
ByPropThink:By Jason Napodano, CFAOn May 13, 2013, Trius Therapeutics (TSRX) announced that it had received a notice of allowance from the USPTO for a patent application relating to the use of its ted...
ADR REPORT-Japanese ADRs rise 1 pct on yen weakness
NEW YORK, May 13 (Reuters) - U.S.-listed shares of Asian companies rose more than 1 percent on Monday, led by gains in top Japanese exporters as the dollar climbed against the yen for a third session....
How to quickly spot signs of stroke
(HealthDay)—Sudden numbness or weakness in the face, arms or legs on one side of the body, confusion and trouble speaking are among the signs that someone is having a stroke. The sooner a stroke is...
Why You Crave Sugary Foods Even if They Taste Like Crap
When, in a moment of weakness, you reach for that chocolate donut or bag of jelly beans, to all appearances your tastebuds are running the show. You imagine the snack's sweet taste; you might even sa...
Nerve Protecting Agents May Help Prevent Chemotherapy-Induced Anemia
Cancer chemotherapy can cause peripheral neuropathy - nerve damage often resulting in pain and muscle weakness in the arms and legs. Now, researchers at Albert Einstein College of Medicine of Yeshiva...
Study: Combination of chemotherapy and nerve-protecting agents can prevent anemia
Cancer chemotherapy can cause peripheral neuropathy-nerve damage often resulting in pain and muscle weakness in the arms and legs. Now, researchers at Albert Einstein College of Medicine of Yeshiva Un...
Bristol-Myers Has The Future Of Oncology Therapies
ByBio Matt: Bristol-Myers (NYSE:BMY) Bristol-Myers recently reported its Q1 2013 financial results with a 27% decline in pharmaceutical revenues towards Q1 2012, but with a 10% increase excluding Av...
CANADA STOCKS-TSX steady as financials offset fall in Catamaran, Goldcorp
* TSX down 7.56 points, or 0.06 percent, at 12,313.73 * Six of 10 main index sectors decline * Goldcorp falls 2 percent after profit drops * Catamaran, Valeant stumble after results * Manulife rises 4...
CANADA STOCKS-TSX slips as resources, healthcare stocks weigh
TORONTO, May 2 (Reuters) - Canada's main stock index turned negative in early Thursday trade, hurt by weakness in materials and energy stocks, as well as declines in healthcare companies Catamaran Cor...
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Clinical Trials
The Survey About Resting Metabolic Rate and Its Related Factors in Terminal Patients
According to data from the Taiwanese government, cancer mortality has been the leading cause of death in Taiwan since 1982. The trend is increasing day by day. As the people are aging in T...
Study of Oral Fampridine-SR in Multiple Sclerosis
Multiple sclerosis (MS) is a disorder of the body's immune system that affects the central nervous system (CNS). Normally, nerve fibers carry electrical impulses through the spinal cord, p...
The specific aim of this project is to improve walking ability in persons following stroke using 'treadmill training plus power training'. This modality addresses the two major impairment...
New Onset Weakness in Critically Ill Patients and the Risk of Death and Recurrent ICU Admission
This study seeks to define the morbidity of critical care polyneuropathy and to confirm that this diagnosis is, in fact, independently associated with increased mortality. Secondary infor...
Genetic Characterization of Parkinson's Disease
This study will explore the risks and causes of Parkinson's disease, a chronic progressive nervous system disorder. Patients typically have tremors, muscle weakness and a shuffling gait....
Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis
This study will determine whether magnetic resonance imaging (MRI) can detect damage to certain parts of the brain and analyze the thickness of the brain's outer surface in patients with m...
Brain Physiology in Polio Survivors
OBJECTIVE: Many persons who survive poliomyelitis develop pain, weakness, and fatigue many decades later. It is not known why some persons develop this syndrome and others do not. One po...
Alemtuzumab to Treat Sporadic Inclusion Body Myositis
This study will examine the safety and effectiveness of alemtuzumab (Campath® (Registered Trademark)) for improving muscle strength in patients with sporadic inclusion body myositis (s-IB...
This study will evaluate the magnetoencephalography (MEG) alone and together with electroencephalography (EEG) in non-invasive presurgical evaluation. It will look at the contribution of t...
Safety and Efficacy Study of Oral Fampridine-SR on Walking Ability in Multiple Sclerosis
Multiple Sclerosis (MS) is a disorder of the body's immune system that affects the Central Nervous System (CNS). Normally, nerve fibers carry electrical impulses through the spinal cord,...
Videos
Keisha White - The Weakness In Me
The music video to Keisha White's The Weakness In Me, taken from the album "Out of My Hands".
Medical and Biotech [MESH] Definitions
Muscular Dystrophies, Limb-girdle
A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).
Tay-sachs Disease, Ab Variant
A progressive neurodegenerative disorder that begins with muscle weakness, then progresses to startle reaction, retardation and seizures. It is characterized by the accumulation of G(M2) GANGLIOSIDE in neurons that is caused by a lack of G(M2) ACTIVATOR PROTEIN function. The AB variant designation refers to the increase of both HEXOSAMINIDASE A and HEXOSAMINIDASE B in tissues that lack of G(M2) activator protein.
Distal Myopathies
A heterogeneous group of genetic disorders characterized by progressive MUSCULAR ATROPHY and MUSCLE WEAKNESS beginning in the hands, the legs, or the feet. Most are adult-onset autosomal dominant forms. Others are autosomal recessive.
Barth Syndrome
Rare congenital X-linked disorder of lipid metabolism. Barth syndrome is transmitted in an X-linked recessive pattern. The syndrome is characterized by muscular weakness, growth retardation, DILATED CARDIOMYOPATHY, variable NEUTROPENIA, 3-methylglutaconic aciduria (type II) and decreases in mitochondrial CARDIOLIPIN level. Other biochemical and morphological mitochondrial abnormalities also exist.
Potassium Deficiency
A condition due to decreased dietary intake of potassium, as in starvation or failure to administer in intravenous solutions, or to gastrointestinal loss in diarrhea, chronic laxative abuse, vomiting, gastric suction, or bowel diversion. Severe potassium deficiency may produce muscular weakness and lead to paralysis and respiratory failure. Muscular malfunction may result in hypoventilation, paralytic ileus, hypotension, muscle twitches, tetany, and rhabomyolysis. Nephropathy from potassium deficit impairs the concentrating mechanism, producing polyuria and decreased maximal urinary concentrating ability with secondary polydipsia. (Merck Manual, 16th ed)
