When Death Is Near - Biotech, Pharma and Life Science Channel
PubMed Articles
Characterization of the LPS-induced inflammation of the adrenal gland in mice.
Systemic administration of endotoxin, which closely mimics the bacteria-induced systemic inflammatory response syndrome (SIRS) can ultimately lead to organ failure. Adrenal gland insufficiency is freq...
MicroRNA-21 and programmed cell death 4 (PDCD4), a downstream target of miR-21, mediate diverse physiological responses. Here we demonstrate that globular adiponectin (gAcrp) modulates expression of m...
Tomato MAPK kinase SlMKK2 is a key protein regulating immunity-associated programmed cell death (PCD) in plants. We examined the role of the N-terminal MAPK-docking site (or D-site) of SlMKK2 in PCD e...
An analysis of heat effects in different subpopulations of Bangladesh.
A substantial number of epidemiological studies have demonstrated an association between atmospheric conditions and human all-cause as well as cause-specific mortality. However, most research has been...
Functional specific roles of FADD: comparative proteomic analyses from knockout cell lines.
Fas-associated death domain (FADD) is a classical adaptor protein involved in tumor necrosis factor receptor family-mediated apoptosis. Besides being an essential instrument in cell death, it also pla...
Neurodegenerative disease: Oxidative stress in cells near amyloid plaques linked to neuronal death.
Applying optimal model selection in principal stratification for causal inference.
Noncompliance to treatment allocation is a key source of complication for causal inference. Efficacy estimation is likely to be compounded by the presence of noncompliance in both treatment arms of cl...
Activation of muscarinic receptors inhibits glutamate-induced GSK-3β overactivation in PC12 cells.
Aim:To investigate the actions of the muscarinic agonist carbachol on glutamate-induced neurotoxicity in PC12 cells, and the underlying mechanisms.Methods:PC12 cells were treated with different concen...
Impact of ad hoc percutaneous coronary intervention with drug-eluting stents in angina patients.
Aims: To evaluate the impact of ad hoc percutaneous coronary intervention (PCI) which combines coronary angioplasty and PCI in the same procedure in the era of drug-eluting stents (DES). Methods and r...
News Articles
Par Pharmaceutical Begins Shipment of Generic Atacand®
WOODCLIFF LAKE, N.J., May 22, 2013 /PRNewswire/ -- Par Pharmaceutical Companies, Inc. today announced that it has entered into an exclusive U.S. supply and distribution agreement with AstraZeneca to d...
Study: Delayed transfer of patients to ICU increases risk of death in hospital
Delayed transfer to the intensive care unit (ICU) in hospitalized patients significantly increases the risk of dying in the hospital, according to a new study from researchers in Chicago.
Patient Prompt® Announces New Drug Adherence Program to Assist in Prescribed Medication Compliance
(PRWEB) May 22, 2013 Poor adherence to appropriate medication therapy has been shown to result in not only medical complications and death (some 125,000 deaths in the U.S. every year are attributed...
Amag investigates anemia drug after report of death in Switzerland
(Reuters) - Amag Pharmaceuticals Inc said its marketing partner in Switzerland, Takeda Pharmaceutical Co Ltd, is recalling a batch of Amag's anemia drug, Rienso, because of a death and several cases o...
CORRECTED-Amag investigates anemia drug after report of death in Switzerland
(Corrects headline to "investigates." Amag did not say the drug caused the fatality.)
Ohio Varicella Death Is Vaccination Wake-up Call
The death of an Ohio teen from varicella should serve as a reminder that catch-up vaccination of older children and adolescents can prevent severe complications and death from infection with varicella...
ImportanceThe goal of oxygen therapy is to deliver sufficient oxygen to the tissues while minimizing oxygen toxicity and oxidative stress. It remains uncertain what values of arterial oxygen saturatio...
Identification Of Molecular Trigger For Alzheimer's Disease
Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease - when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of...
Blood-Brain Barrier Integrity Suffers Days After Ischemic Stroke Leading To Serious Complications
While the effects of acute stroke have been widely studied, brain damage during the subacute phase of stroke has been a neglected area of research. Now, a new study by the University of South Florida...
Sleep Apnea Patients At Increased Mortality Risk May Be Identified By Stress Test
Many studies have shown that men and women who suffer from obstructive sleep apnea (OSA) - a disorder that causes breathing to halt intermittently during sleep - have a higher mortality rate than thos...
Events
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Companies
TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat deb...
Corboy & Demetrio is one of the nationâs premier law firms. It represents individuals and their families in serious personal injury and wrongful death cases and is renowned f...
Corboy & Demetrio is one of the nationâs premier law firms. The personal injury law firm represents individuals and their families in serious personal injury and wrong...
Sepsis Alliance is a nonprofit patient advocacy organization in the U.S. promoting awareness of sepsis. Sepsis Alliance operates by providing information and education to raise aw...
The California injury lawyers at Estey Bomberger represent victims of serious injury and wrongful death due to the negligence or willful misconduct of others. The attorneys have s...
Based in Eden Prairie, Minn., NeoChord is a privately held medical technology company focused on advancing the treatment of mitral regurgitation. The Company expects to commercial...
Based in Eden Prairie, Minn., NeoChord is a privately held medical technology company focused on advancing the treatment of mitral regurgitation. The Company received CE marking i...
Partnership to Fight Chronic Disease (PFCD)
PFCD is a national coalition of patients, providers, community organizations, business and labor groups, and health policy experts committed to raising awareness of the number one...
Acusphere (ACUS.PK) is a specialty pharmaceutical company that develops new drugs and improved formulations of existing drugs using its proprietary microsphere technology. We are...
Cardiovascular disease is the leading cause of death globally. Astonishingly, in the United States, every 37 seconds a person dies from cardiovascular disease. For survivors, life...
Clinical Trials
Ventricular Arrhythmias in Uremic Cardiomyopathy
There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds...
Vemurafenib, Cetuximab, and Irinotecan in Advanced Solid Cancers
The goal of this clinical research study is to find the highest tolerable dose of vemurafenib that can be given in combination with cetuximab and irinotecan to patients with advanced cance...
The objective is to obtain initial information regarding the safety and efficacy of the use of Filgrastim in the setting of acute myocardial infarction. The secondary objectives are to ob...
Family Preparation Study For Withdrawal of Mechanical Ventilation From Their Family Member
Using the self-regulation theory, an intervention to prepare families for that experience was developed. This study will assess the impact of the intervention on a family’s evaluation of...
Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-Year Manometric Follow-Up
Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. In...
PS-341 With Oral Temozolomide in Patients With Advanced Refractory Solid Tumors or Melanoma
Patients are asked to participate in this research because they have been diagnosed as having cancer that is not curable by any standard means including surgery or radiation therapy or oth...
Cetuximab, Capecitabine, Oxaliplatin and Bevacizumab in Advanced Colorectal Cancer
This is a study to assess the efficacy and safety of the addition of cetuximab to the combined regimen of capecitabine, oxaliplatin and bevacizumab in patients with previously untreated ad...
The Survey About Resting Metabolic Rate and Its Related Factors in Terminal Patients
According to data from the Taiwanese government, cancer mortality has been the leading cause of death in Taiwan since 1982. The trend is increasing day by day. As the people are aging in T...
Chronic transplant nephropathy and cardiovascular death are the main reasons for loss of transplanted organs after kidney transplantation. Vascular changes, induced by hypertension and/or...
Naltrexone Implants vs. MMT Among Inmates in the Norwegian Correctional Services
The purpose of this clinical trial is to study the efficacy and safety of naltrexone implants as a relapse prevention for opiate addicted inmates about to be released from prison. The expe...
Videos
When Death Is Near
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Medical and Biotech [MESH] Definitions
Wasting Disease, Chronic
A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).
Posthumous Conception
Conception after the death of the male or female biological parent through techniques such as the use of gametes that have been stored during his or her lifetime or that were collected immediately after his or her death.
Shaken Baby Syndrome
Brain injuries resulted from vigorous shaking of an infant or young child held by the chest, shoulders, or extremities causing extreme rotational cranial acceleration. It is characterized by the intracranial and intraocular hemorrhages with no evident external trauma. Serious cases may result in death.
Genes, Transgenic, Suicide
Genes that are used transgenically, i.e., via GENE TRANSFER TECHNIQUES to induce CELL DEATH.
Sexual Development
The processes of anatomical and physiological changes related to sexual or reproductive functions during the life span of a human or an animal, from FERTILIZATION to DEATH. These processes include SEX DIFFERENTIATION; SEXUAL MATURATION; and changes during AGING.
