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Clinical Research Organization Research

06:47 EST 19th February 2017 | BioPortfolio

Judith Eve Kingston.

Doctor is allowed to practise again as reinstatement becomes less rare.

Impact of searching clinical trial registries in systematic reviews of pharmaceutical treatments: methodological systematic review and reanalysis of meta-analyses.

Objective To evaluate the impact of searching clinical trial registries in systematic reviews.Design Methodological systematic review and reanalyses of meta-analyses.Data sources Medline was searched to identify systematic reviews of randomised controlled trials (RCTs) assessing pharmaceutical treatments published between June 2014 and January 2015. For all systematic reviews that did not repor...

Development of the Critical Care Pharmacotherapy Trials Network.

The development of the Critical Care Pharmacotherapy Trials Network (CCPTN) as a model for practice-based pharmacotherapy research is described.

Michael John Aldridge.

Screening does not reduce mental disorders in returning soldiers, study finds.

Experts debate Trump's mental health in US press.

Hypoxia Selectively Enhances Integrin Receptor Expression to Promote Metastasis.

Metastasis is the leading cause of breast cancer (BCa)mortality. Previous studies have implicated hypoxia-induced changes in the composition and stiffness of the extracellular matrix (ECM) in the metastatic process. Therefore, the contribution of potential ECM binding receptors in this process was explored. Using a bioinformatics approach the expression of all integrin receptor subunits, in two in...

Robert P C MacDonald.

NHS cuts have played part in rise in excess deaths, study claims.

A Program Aimed toward Inclusive Excellence for Underrepresented Undergraduate Women in the Sciences.

Created to foster inclusive excellence, Smith College's Achieving Excellence in Mathematics, Engineering, and Science (AEMES) Scholars program provides early faculty-mentored research opportunities and other programming as a way to foster success in academic outcomes for underrepresented women in science. Using academic record data, we compared Scholars' outcomes over time with those of underrepre...

Why Work with Undergraduate Researchers? Differences in Research Advisors' Motivations and Outcomes by Career Stage.

Undergraduate research is often hailed as a solution to increasing the number and quality of science, technology, engineering, and mathematics graduates needed to fill the high-tech jobs of the future. Student benefits of research are well documented but the emerging literature on advisors' perspectives is incomplete: only a few studies have included the graduate students and postdocs who often se...

Fidelity of Implementation: An Overlooked Yet Critical Construct to Establish Effectiveness of Evidence-Based Instructional Practices.

The discipline-based education research (DBER) community has been invested in the research and development of evidence-based instructional practices (EBIPs) for decades. Unfortunately, investigations of the impact of EBIPs on student outcomes typically do not characterize instructors' adherence to an EBIP, often assuming that implementation was as intended by developers. The validity of such findi...

Frederic Salkeld Plumpton.

Health information needs, source preferences and engagement behaviours of women with metastatic breast cancer across the care continuum: protocol for a scoping review.

The health information needs, information source preferences and engagement behaviours of women with metastatic breast cancer (mBC) depend on personal characteristics such as education level, prior knowledge, clinical complications, comorbidities and where they are in the cancer journey. A thorough understanding of the information behaviours of women living with mBC is essential to the provision o...

Understanding the epidemiology of avoidable significant harm in primary care: protocol for a retrospective cross-sectional study.

Most patient safety research has focused on specialist-care settings where there is an appreciation of the frequency and causes of medical errors, and the resulting burden of adverse events. There have, however, been few large-scale robust studies that have investigated the extent and severity of avoidable harm in primary care. To address this, we will conduct a 12-month retrospective cross-sectio...

Bariatric surgery cuts hyperglycaemia in diabetes more than drugs alone, study finds.

Circulating microRNAs and diabetes mellitus: a novel tool for disease prediction, diagnosis, and staging?

Diabetes is a complex, multifactorial group of metabolic diseases characterized by chronic hyperglycaemia due to pancreatic beta-cell dysfunction and/or loss. It is characterized by an asymptomatic and highly variable prodromic phase, which renders diabetes mellitus difficult to be predicted with sufficient accuracy. Despite several efforts in the identification and standardization of newly trusta...

Postural tachycardia syndrome and suicide: what we don't know.

Barriers to Healthcare among African Immigrants in Georgia, USA.

African-born immigrants are among the fastest growing immigrant groups in the US, yet they are underrepresented in healthcare research, particularly, cancer research and tend to be categorized as African American or Black, obscuring any cultural nuances that exist. A survey designed to provide insight on the barriers to healthcare, knowledge of common cancers, and cancer risks was utilized during ...

Announcments for issue 3, 2017.

Erratum to: Impact of old age on patient-report outcomes and cost utility for anterior cervical discectomy and fusion surgery for degenerative spine disease.

Erratum to: First clinical results of minimally invasive vector lumbar interbody fusion (MIS-VLIF) in spondylodiscitis and concomitant osteoporosis: a technical note.

Letter to the Editor concerning "Association between IGF1 gene single nucleotide polymorphism (rs5742612) and adolescent idiopathic scoliosis: a meta-analysis" by M. Guan et al. (Eur Spine J; 2016. doi:10.1007/s00586-016-4742-7).

Reply to the Letter to the Editor of Y. Zhao, et al. concerning "Association between IGF1 gene single nucleotide polymorphism (rs5742612) and adolescent idiopathic scoliosis: a meta-analysis" by Ming Guan, Huan Wang et al. Eur Spine J (2016). doi:10.1007/s00586-016-4742-7.

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