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Genentech, Inc. Company Profile

20:27 EST 23rd February 2017 | BioPortfolio

Founded more than 35 years ago, Genentech is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. The company, a member of the Roche Group, has headquarters in South San Francisco, California.

Research
Genentech conducts basic and applied research in the areas of in Oncology, Immunology, Neuroscience, Metabolism, and Infectious Disease. Genentech's approximately 1,200 researchers and scientists and 135 postdocs consistently publish important papers in prestigious journals and are among the total citations.

Pipeline
Genentech's development pipeline continues to grow, with multiple promising projects in the following therapeutic focus areas: Oncology, Immunology, Neuroscience, Metabolism, and Infectious Disease. Genentech's clinical development pipeline includes monoclonal antibodies, small molecules, and antibody drug conjugates that address serious unmet medical needs.

Key Products
Since the company was founded in 1976, Genentech has focused its drug discovery efforts on medicines that address significant unmet medical needs. Today Genentech has multiple products on the market for serious or life-threatening medical conditions. In March 2009, Genentech became a member of the Roche Group, and Genentech now serves as the headquarters for all Roche pharmaceutical operations in the United States. Accordingly, the list below includes products, which were previously marketed as Roche products that are now being marketed by Genentech in the United States.

BIOONCOLOGY
Avastin® (bevacizumab)
Erivedge® (vismodegib)
Herceptin® (trastuzumab)
Kadcyla™ (ado-trastuzumab emtansine)
Perjeta® (pertuzumab)
Rituxan® (rituximab-BioOncology)
Tarceva® (erlotinib)
Xeloda® (capecitabine)
Zelboraf® (vemurafenib)

IMMUNOLOGY AND OPHTHALMOLOGY
Actemra® (tocilizumab)
Lucentis™ (ranibizumab injection)
Rituxan® (rituximab - Immunology)
Xolair® (omalizumab)

METABOLISM & PRIMARY CARE
Activase® (alteplase)
Cathflo Activase® (alteplase)
Nutropin AQ® (somatropin (rDNA origin) for injection)
TNKase® (tenecteplase)

VIROLOGY & SPECIALTY CARE
CellCept® (mycophenolate mofetil)
Pegasys® (peginterferon alfa-2a)
Pulmozyme® (dornase alfa)
Tamiflu® (oseltamivir phosphate)
Valcyte® (valganciclovir hydrochloride)

OTHER PRODUCTS
Anaprox® (naproxen sodium)
Boniva Injection® (ibandronate sodium)
Boniva Tablets® (ibandronate sodium)
Cytovene® (ganciclovir)
EC-Naprosyn® (naproxen)
Fuzeon® (enfuvirtide)
Invirase® (saquinavir mesylate)
Klonopin® (clonazepam)
Kytril Injection™ (granisetron HCL)
Kytril Tablets® (ganisetron HCL)
Naprosyn® (naproxen)
Rocephin® (ceftriaxone)
Roferon-A® (interferon alfa-2a)
Romazicon® (flumazenil)
Valium ® (diazepam)
Xenical® (orlistat)
Zenapax® (daclizumab)

Source: http://www.gene.com/medical-professionals/medicines

Location

1 DNA Way
South San Francisco
CA
94080
USA

Contact

Phone: (650) 225-1000
Fax: (650) 225-6000


News Articles [277 Associated News Articles listed on BioPortfolio]

Anderson to succeed Clark as Genentech CEO

The Genentech Inc. unit of Roche (SIX:ROG; OTCQX:RHHBY) named Bill Anderson CEO, effective Jan. 1. He replaces Ian Clark, who is retiring.Anderson will remain head of North American operations for Roc...

Genentech's eye drug gets FDA OK for new indication

Genentech's Lucentis, or ranibizumab injection, has been approved by the FDA as a treatment for myopic choroidal neovasculari -More- 

Roche’s Genentech Names Insider Bill Anderson New CEO

The Genentech division of Roche said that Bill Anderson, who has been with the company for a decade, will replace Ian Clark as CEO. Anderson has been running North American commercial operations, the ...

Genentech announces replacement for retiring boss

Genentech, the US-based biotech unit of Swiss pharma giant Roche, has announced its new chief executive…

Charles River, Genentech extend partnership

Charles River Laboratories International has extended its longstanding integrated drug discovery alliance with Genentech, a member of the Roche Group. “We are proud to work with Genentech to identif...

G1 and Genentech enter small cell lung cancer trial collaboration

G1 Therapeutics Inc. and Genentech Inc. entered into a trial collaboration to investigate the combination of G1’s trilaciclib (G1T28) with Genentech’s Tecentriq (atezolizumab) for patients with sm...

BRIEF-Genentech withdraws counterclaim against Exelixis in JAMS arbitration

* Update on dispute between Exelixis and Genentech, a member of the Roche group

Genentech's injection for eye disorders wins FDA nod

Genentech's Lucentis, or ranibizumab injection, has been approved by the FDA to treat wet age-related macular degeneration an -More- 

Drugs and Medications [12 Associated Drugs and Medications listed on BioPortfolio]

Boniva [Genentech, Inc.]

These highlights do not include all the information needed to use BONIVA Tablets safely and effectively. See full prescribing information for BONIVA Tablets. BONIVA (ibandronate sodium) Tablets Initia...

Copegus [Genentech, Inc.]

These highlights do not include all the information needed to use COPEGUS safely and effectively. See full prescribing information for COPEGUS. COPEGUS (ribavirin) Tablets Initial U.S. Approval: 2002

Pegasys [Genentech, Inc.]

These highlights do not include all the information needed to use PEGASYS safely and effectively. See full prescribing information for PEGASYS. PEGASYS® (peginterferon alfa-2a)Injection for Subcutan...

Boniva [Genentech, Inc.]

BONIVA (ibandronate sodium) INJECTION

Pulmozyme [Genentech, Inc.]

Pulmozyme (dornase alfa)Inhalation Solution

PubMed Articles [10 Associated PubMed Articles listed on BioPortfolio]

Aflibercept for Diabetic Macular Edema in Eyes Previously Treated With Ranibizumab and/or Bevacizumab May Further Improve Macular Thickness.

To evaluate the short-term anatomic and visual outcomes after aflibercept (Eylea; Regeneron, Tarrytown, NY) in eyes with diabetic macular edema (DME) previously treated with ranibizumab (Lucentis; Gen...

Hepatotoxicity with Vismodegib: An MD Anderson Cancer Center and Research on Adverse Drug Events and Reports Project.

On 30 January 2012, the US FDA approved vismodegib (Erivedge(®), Genentech, CA, USA) for the management of both metastatic and locally advanced basal cell carcinoma.

Nonresponse and Recurrence of Retinopathy of Prematurity After Intravitreal Ranibizumab Treatment.

To evaluate the surgical outcome of type 1 retinopathy of prematurity (ROP) after intravitreal ranibizumab (IVR) (Lucentis; Genentech, South San Francisco, CA) treatment.

The Role of Anti-VEGF Therapy in the Treatment of Diabetic Macular Edema.

Diabetic retinopathy (DR) is the leading cause of blindness among working-age adults. DR often leads to diabetic macular edema (DME), which often goes unnoticed until a patient presents with vision lo...

TU-D-207B-07: Radiomic Response Assessment for Recurrent Glioblastoma Treated with Bevacizumab in the BRAIN Trial.

To develop radiomic biomarkers for non-invasive response assessment of Bevacizumab (Avastin; Genentech) treatment in recurrent glioblastoma multiforme (GBM).

Clinical Trials [34 Associated Clinical Trials listed on BioPortfolio]

Mechanisms of Exacerbation of Asthma

The purpose of this study is to identify the causes of asthma that were not previously suspected, to better understand the effects of inhaled steroids on asthma and to identify new way to ...

Study of the Mechanisms of Asthma

The purpose of this study is to identify the causes of asthma that were not previously suspected, to better understand the effects of inhaled steroids on asthma and to identify new way to ...

A Study of GDC-0449 (Hedgehog Pathway Inhibitor) in Patients Treated With GDC-0449 in a Previous Genentech-Sponsored Phase I or II Cancer Study

This is a multicenter, open-label extension study. Patients receiving GDC-0449 in a Genentech-sponsored study who have completed the parent study or who continue to receive GDC-0449 at th...

An Extension Study to Evaluate Avastin in Patients Treated in a Previous Genentech-Sponsored Cancer Study

This is a multicenter, open-label extension study. Subjects who have received rhuMAb VEGF (Avastin) therapy in any Genentech-sponsored Phase I or Phase II cancer study and who did not sho...

An Extension Study to Provide Continued Avastin Therapy to Patients With Solid Tumours Who Were Previously Enrolled in a Roche/Genentech Sponsored Study

This single-arm, open-label, multicentre extension study will provide continued Avastin [bevacizumab] therapy to patients with solid tumours who were previously enrolled in a Roche/Genente...

Companies [41 Associated Companies listed on BioPortfolio]

VaxGen Incorporated

VaxGen were formed to continue development of AIDSVAX in partnership with Genentech. In connection with our formation, Genentech licensed to us the technology necessary for completing development and ...

Genentech, Inc.

Founded more than 35 years ago, Genentech is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening me...

Genentech

Considered the founder of the biotechnology industry, Genentech has been delivering on the promise of biotechnology for more than 30 years, using human genetic information to discover, develop, commer...

Lpath

Lpath, Inc., headquartered in San Diego, California, is a theranostics company focused on bioactive signaling lipids as targets for treating and diagnosing important human diseases. Lpath's lead produ...

ImmunoGen, Inc.

ImmunoGen, Inc. develops targeted anticancer therapeutics using its expertise in cancer biology, monoclonal antibodies and the creation and attachment of potent cell-killing agent...

More Information about "Genentech, Inc." on BioPortfolio

We have published hundreds of Genentech, Inc. news stories on BioPortfolio along with dozens of Genentech, Inc. Clinical Trials and PubMed Articles about Genentech, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Genentech, Inc. Companies in our database. You can also find out about relevant Genentech, Inc. Drugs and Medications on this site too.

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