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The single-group, multi-dose study examined the ability of the Rx Guardian(SM) algorithm to differentiate among low, medium and high daily doses of OxyContin®. Oxycodone levels were detected in the urine of 36 healthy volunteers using a liquid chromatography-mass spectrometry (LC-MS-MS) assay. Participants were randomized to receive 80mg, 160mg or 240mg of daily OxyContin® to steady state conditions. Urine samples were collected during days three and four. Concordance was tested between pairs of third and fourth day results for both raw and normalized (algorithm-adjusted) LC-MS-MS values for each participant. An analysis of medians was conducted for each of the dosage groupings using Bonett-Price confidence intervals. A Bonferroni adjustment was applied to the confidence intervals to adjust for the multiple comparisons made in the study.
Deal Boosts Industry-Leading Chronic Pain Intervention and UR Services Offerings Genex Services, a leader in medical cost-containment and disability management services...
Ameritox is the nationâs leader in Pain Medication Monitoring SolutionsÂ®, offering specialized laboratory testing and reporting services. Ameritoxâs expertise and inn...
The single-group, multi-dose study examined the ability of the Rx Guardian(SM) algorithm to differentiate among low, medium and high daily doses of OxyContin®. Oxycodone levels were detected in the ...
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Benign Prostatic Hyperplasia (BPH) Erectile Dysfunction Urology Urology is the branch of medicine concerned with the urinary tract and diseases that affect it. Examples include urethritis, urethrostenosis and incontinence. Urology is a su...
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...
An assay is an analytic procedure for qualitatively assessing or quantitatively measuring the presence or amount or the functional activity of a target entity. This can be a drug or biochemical substance or a cell in an organism or organic sample. ...