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Expression Genetics, Inc. Company Profile

07:15 EDT 23rd September 2017 | BioPortfolio

Expression Genetics, Inc. (EGEN), is a privately held biopharmaceutical company specializing in nucleic acid (DNA and RNAi) delivery and therapeutics aimed at specific disease targets. The Company, with laboratories and headquarters in Huntsville, Alabama, is focused on developing therapeutics for the treatment of human diseases including cancer and cardiovascular disease. The Company has a significant intellectual property position in biocompatible polymers, their novel compositions with nucleic acids, and their therapeutic applications. EGEN has research pipeline products aimed at treatment of various cancers and cardiovascular disease involving siRNA, shRNA, tumor antigens, and angiogenic genes. EGEN has collaborations with outside investigators, biotech organizations and universities on various projects in these areas.


News Articles [1083 Associated News Articles listed on BioPortfolio]

Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator

Lipid production in the oleaginous microalga Nannocholoropsis gaditana is doubled by decreasing the expression of a transcriptional regulator identified through a CRISPR–Cas9 reverse-genetics approa...

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

The authors identified a protective genetic allele associated with lower PU.1 (SPI1) expression in myeloid cells by conducting a genome-wide scan of Alzheimer's disease (AD). PU.1 binds the promoters ...

Tumour PD-L2 expression may predict patient response to anti-PD-1 immunotherapy

PD-L2 protein expression in human tumours was associated with clinical response to pembrolizumab (Keytruda), an anti-PD-1 immunotherapy, independent of PD-L1 expression, in patients with head and neck...

Tumor PD-L2 expression may predict patient response to anti-PD-1 immunotherapy

(American Association for Cancer Research) PD-L2 protein expression in human tumors was associated with clinical response to pembrolizumab (Keytruda), an anti-PD-1 immunotherapy, independent of PD-L1 ...

H. Lundbeck A/S: Lundbeck collaborates on large first-of-its kind study of links between genetics and psychiatric disorders

25,000 patients will be enrolled in the first study ever to combine data from genetics, cognitive tests and online surveys to explore how genetics is related to Major Depressive Disorder, Bipolar D...

Expression of intelectin-1 in bronchial epithelial cells of asthma is correlated with T-helper 2 (Type-2) related parameters and its function

Intelectin-1 (ITLN-1) is secreted by intestinal goblet cells and detectable in blood. Its expression is increased in IL-13-overexpressing mouse airways. However, its expression and function in human a...

Evaluation of Gaussia luciferase and foot-and-mouth disease virus 2A translational interrupter chimeras as polycistronic reporters for transgene expression

The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy monitoring of luciferase activity. We so...

Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis

Long-range enhancer interactions regulate gene expression, yet how they influence CNS development and disease remains unclear. Glasgow et al. identified glia-specific elements and 3D chromatin archite...

Drugs and Medications [11 Associated Drugs and Medications listed on BioPortfolio]

Expression [Zenith Medicosm SL]

Drug Facts

Expression [Zenith Medicosm SL]

Drug Facts

Esika [Ventura Corporation LTD.]

Expression ANTIPERSPIRANT ROLL-ON DEODORANT

Retin-a micro [Ortho-McNeil Pharmaceuticals]

RETIN-A MICRO® (tretinoin gel) microsphere, 0.1% and 0.04%

Retin-a micro [Physicians Total Care, Inc.]

RETIN-A MICRO® (tretinoin gel) microsphere, 0.1% and 0.04%

PubMed Articles [5305 Associated PubMed Articles listed on BioPortfolio]

The regulation of tetraspanin 8 gene expression-A potential new mechanism in the pathogenesis of bipolar disorder.

In a previous study, we identified the single nucleotide polymorphism (SNP) rs4500567, located in the upstream region of tetraspanin 8 (TSPAN8), to be associated with bipolar disorder (BD). Due to its...

Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence.

Nicotine dependence (ND) has a reported heritability of 40-70%. Low-coverage whole-genome sequencing was conducted in 1,889 samples from the UCSF Family study. Linear mixed models were used to conduct...

The Clinic Is My Laboratory: Life as a Clinical Geneticist.

Clinical genetics is the application of advances in genetics and medicine to real human families. It involves diagnosis, care, and counseling concerning options available to affected individuals and t...

Effect of everolimus on the expression of Ki-67 and caspase-3 in patients with neuroendocrine tumors.

Tumors, especially neuroendocrine tumors (NETs), can cause adverse effects on human health. The expression and significance of Ki-67 and caspase-3 in NET remain to be further explored. Everolimus is a...

Introduction to behavioral phenotypes in medical genetics.

Clinical Trials [1544 Associated Clinical Trials listed on BioPortfolio]

Genetics of Women With Lobular Carcinoma in Situ of the Breast

RATIONALE: Gathering information about genetic changes in patients with lobular carcinoma in situ of the breast may help doctors learn more about the disease and find better methods of tre...

Genetics Education: Preparing Physicians for the Future

This study examines the best way to teach genetics to family medicine residents. First year family medicine residents at the University of Toronto will be taught basic clinical genetics as...

Experiences of Genetics Patients With Visible Abnormalities Who Facilitate Teaching in Genetics Clinics

This study will describe the experience of patients with visible physical abnormalities in the genetics clinic when they are involved in teaching others about their condition. Information ...

Virtual Reality Intervention in Cancer Genetics

The goal of this study is to evaluate a virtual reality-based intervention for training health care providers who are not genetics specialists to effectively communicate with and counsel p...

Genetic Studies in Liver Cancer Patients

Hepatocellular carcinoma (HCC) is one the most common malignancies in the world, especially in sub-Saharan Africa and Southeast Asia. Since 1984, it has been the leading cause of cancer de...

Companies [308 Associated Companies listed on BioPortfolio]

AccessDNA, Inc.

AccessDNA is the leading online consumer resource for genetics. The company combines high-quality content about genetics with access to, and evaluation of, relevant testing, couns...

Population Genetics

Harnessing The Power of Populations™ Population Genetics’ approach takes the process of genetic analysis one step further. It enables the elaboration and testing of distinct hypotheses...

Ambry Genetics Corporation

Ambry Genetics is a privately held healthcare company with the industry’s most comprehensive suite of genetic testing solutions, benefiting 90% of all U.S. patients covered b...

Interleukin Genetics, Inc.

Interleukin Genetics, Inc. (OTCQB: ILIU) develops and markets a line of genetic tests under the Inherent Health® brand. The products empower individuals to prevent ce...

Oxford Expression Technologies

Oxford Expression Technologies is a world-renowned centre of excellence for baculovirus protein expression. We provide protein expression products, services and consultancy to many global pharmaceutic...

More Information about "Expression Genetics, Inc." on BioPortfolio

We have published hundreds of Expression Genetics, Inc. news stories on BioPortfolio along with dozens of Expression Genetics, Inc. Clinical Trials and PubMed Articles about Expression Genetics, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Expression Genetics, Inc. Companies in our database. You can also find out about relevant Expression Genetics, Inc. Drugs and Medications on this site too.

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DNA sequencing
DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. During DNA sequencing, the bases of a small fragment of DNA are sequentially identified from signals emitted as each fragment is re-synthesized from a ...


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