The William E. Proudford Sickle Cell Fund Company Profile

22:10 EDT 22nd September 2017 | BioPortfolio

News Articles [2739 Associated News Articles listed on BioPortfolio]

Natural Mutations and Sickle Cell Anaemia

Using the gene-editing technique CRISPR, a UNSW Sydney-led team of scientists has introduced a beneficial natural mutation into blood cells, switching on production of foetal haemoglobin. This advanc...

PCORI Board awards $18 million for two new studies on sickle cell disease

The Patient-Centered Outcomes Research Institute Board of Governors today approved about $18 million to fund two studies comparing different ways to manage the transition of people with sickle cell di...

Sickle Cell Therapy Drought Ends

After nearly 20 years without new treatments for sickle cell disease, the FDA has approved L-glutamine oral powder to reduce severe complications of the blood disorder in patients aged 5 years or olde...

EMA grants priority review to sickle cell disease candidate

The European Medicines Agency has given PRIME designation to Global Blood Therapeutics’ sickle cell…

Emergency Department Oligoanalgesia for Sickle Cell Vaso-Occlusive Crisis

A retrospective comparison of care in an ED versus a specialized sickle cell clinic finds ED analgesia to be stingy.

FDA approves first new sickle cell drug in 20 years

The FDA approved a new medicine, made by Emmaus Medical, Friday to reduce the complications associated with sickle cell disease, a rare blood disorder.

New SOC in sickle cell?

Emmaus’ Endari could become the backbone of future sickle cell therapy.

EMA Says Yes To First Sickle Cell Drug For PRIME

Investigational drugs for sickle cell disease and diffuse large B cell lymphoma from Global Blood Therapeutics and Roche respectively have...   

PubMed Articles [5853 Associated PubMed Articles listed on BioPortfolio]

Decompensated Cirrhosis and Sickle Cell Disease: Case Reports and Review of the Literature.

Although its prevalence is unknown, liver involvement by sickle cell disease is not uncommon and encompasses different clinical spectra including non cholestatic and cholestatic disorders. Few data ha...

Congolese children with sickle cell trait may exhibit glomerular hyperfiltration: A case control study.

The prevalence of sickle cell trait is extremely high in sub-Saharan Africa. Recent studies have reported the impact of sickle cell carriers on renal function. However, data on renal abnormalities in ...

Treatments for priapism in boys and men with sickle cell disease.

Sickle cell disease comprises a group of genetic haemoglobin disorders. The predominant symptom associated with sickle cell disease is pain resulting from the occlusion of small blood vessels by abnor...

Acute Sickle Cell Orbitopathy Masquerading as Orbital Cellulitis.

Sickle cell orbitopathy is a rare manifestation of a sickle cell crisis and can closely mimic orbital cellulitis, both clinically and radiologically. We present a case where a child presented with wha...

Managing acute complications of sickle cell disease in pediatric patients digest.

Sickle cell disease is a chronic hematologic disease with a variety of acute, and often recurring, complications. Vaso-occlusive crisis, a unique but common presentation in sickle cell disease, can be...

Clinical Trials [5273 Associated Clinical Trials listed on BioPortfolio]

Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease

To determine the retinal and choroidal thickness in patients with sickle cell disease compared to age, race matched population without sickle cell disease to allow a better understanding o...

Dose-Escalation Study of SCD-101 in Sickle Cell Disease

The purpose of this study is to determine the safety and clinical effects of SCD-101 when given to adults with sickle cell disease. SCD-101 inhibits sickling of red blood cells containing ...

Cerebrovascular Involvement in Sickle Cell Disease - Comprehensive Sickle Cell Center

To continue studies on the two major neurological complications of sickle cell disease (SCD): namely, stroke and chronic encephalopathy.

Multi-center Study of SC411 for Sickle Cell Disease

The purpose of this study is to determine whether treatment of sickle cell patients with docosahexaenoic omega-3 acid (DHA) is effective in prevention of acute sickle cell crisis.

Prevention of Cerebral Infarction in Sickle Cell Anemia - Comprehensive Sickle Cell Center

To conduct a prospective study aimed at the early detection and treatment of cerebral vascular disease prior to irreversible brain injury in young children with sickle cell anemia (SCA).

Companies [1467 Associated Companies listed on BioPortfolio]

The William E. Proudford Sickle Cell Fund

Sickle Cell Foundation of Tennessee

“Our mission is to provide social services, including health, education and life skills, to enhance the quality of life and self-sufficiency of individuals living with Sickle...

Imara Inc.

Imara Inc., a Cydan Development company, is dedicated to developing novel therapeutics for patients with sickle cell disease. Imara is developing IMR-687, a highly s...

National Stomp Out Sickle Cell Walk

Emmaus Life Sciences, Inc.

Emmaus Life Sciences is dedicated to the discovery, development and commercialization of innovative treatments and therapies for rare diseases. The Company’s research on sick...

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