Gene Expression Technologies Company Profile
Gene Expression Technologies Limited (GET) is a biopharmaceutical company established to develop and commercialise Gene ICE™, a unique and proprietary platform for gene expression regulation. This technology is being used to develop a new class of novel therapeutic agent and to facilitate GET's own programmes for drug target discovery. Gene ICE™ is also now available to pharmaceutical and biotech partners for the fast, specific and efficient functional validation of drug targets.
Gene ICE™ was developed at London's Imperial College School of Medicine, and GET was spun-out of Imperial College in October 2000. During February 2002 GET successfully completed a private placement to secure first round funding. The Company is now located in Central London, at the London BioScience Innovation Centre.
Location
47 Price's Gate, Exhibition Road
London
SW7 2QA
United Kingdom
Contact
Phone: +44 (0) 207 594 6824
Fax: +44 (0) 207 594 6584
News Articles
Major flaw in standard approach to global gene expression analysis
Whitehead Institute researchers report that common assumptions employed in the generation and interpretation of data from global gene expression analyses can lead to seriously flawed conclusions about...
Cancer biology: A genome-wide 'on' switch
A common cancer gene works not by implementing unique gene-expression patterns as previously thought, but rather by boosting the expression of almost all active genes, according to work from two indep...
New Whitepaper Compares Gene Expression Analysis Technologies
Plexpress helps researchers to make an informed choicePlexpress, developer of the innovative TRAC platform for high-throughput gene expression analysis, has released a free-to-download whitepaper en...
Stanford scientists develop tool to provide deeper analysis of microarray data
A new software program designed by scientists at the Stanford University School of Medicine enables researchers to see the whole picture of gene expression in a sample. The program, called the Gene Ex...
Adenosylcobalamin is a form of vitamin B12 that serves as a coenzyme in different reactions and as a ligand for riboswitches to control bacterial gene expression. The crystal structure of a B12 ribosw...
Regulation of human papillomavirus gene expression by splicing and polyadenylation
The ability of human papillomaviruses (HPVs) to cause disease is strongly dependent on the strict coordination of viral gene expression with the differentiation state of the infected cell. Here, Johan...
Precise and reliable gene expression via standard transcription and translation initiation elements
By using a bicistronic design, with a leader peptide that overlaps with and contains the Shine-Dalgarno site for a downstream gene of interest, the authors demonstrate reliable, context-independent ge...
Single-molecule analysis of gene expression using two-color RNA labeling in live yeast
Tagging of single transcripts with two fluorescent markers can be used to study many aspects of gene expression, including intrinsic noise in transcription or polymerase dynamics at a single gene.
Drugs and Medications
Expression [Zenith Medicosm SL]
Drug Facts
Expression [Zenith Medicosm SL]
Drug Facts
Esika [Ventura Corporation LTD.]
Expression ANTIPERSPIRANT ROLL-ON DEODORANT
Retin-a micro [Ortho-McNeil Pharmaceuticals]
RETIN-A MICRO® (tretinoin gel) microsphere, 0.1% and 0.04%
Retin-a micro [Physicians Total Care, Inc.]
RETIN-A MICRO® (tretinoin gel) microsphere, 0.1% and 0.04%
PubMed Articles
Effect of FAK, DLC-1 gene expression on OVCAR-3 proliferation.
The study investigates the effect of FAK, DLC-1 on OVCAR-3 proliferation. FAK gene siRNA vector recombinant plasmid was constructed using RNA interference technique. FAK gene-transfected OVCAR-3 cells...
NRIP enhances HPV gene expression via interaction with either GR or E2.
We previously identified a gene, nuclear receptor-interaction protein (NRIP), which functions as a transcription cofactor in glucocorticoid receptor (GR) and human papillomavirus E2 (HPV E2)-driven ge...
SNP-based large-scale identification of allele-specific gene expression in human B cells.
Polymorphism and variations in gene expression provide the genetic basis for human variation. Allelic variation of gene expression, in particular, may play a crucial role in phenotypic variation and d...
Applying gene expression microarrays to pulmonary disease.
Gene expression microarrays are high throughput technologies that can simultaneously measure the expression levels of most known genes in the human genome within a biological sample. The study of gene...
Six1 and Six1 cofactor expression is altered during early skeletal muscle overload in mice.
Six1 is a transcription factor that, along with cofactors (Eya1, Eya3, and Dach2), regulates skeletal muscle fiber-type and development. SIX1 (human) gene expression decreases after overload, but the...
Clinical Trials
The Gene Expression Studies of the Role of Tumor Microenvironments in Tumor Progression
The purpose of this study is to analyze the gene expression patterns associated with various microenvironmental stresses in tumors to understand their roles in tumor progression and treatm...
DNA Microarray Analysis of Gene Expression in Chronic Rhinosinusitis
Analysis of differential gene expression in patients with chronic rhinosinusitis without polyps compared to unaffected patients. Correlation of abnormal gene expression with surgical outco...
Construction and Use of Lung Tumor Microarray for the Analysis of Gene Expression in Lung Cancer
The proposed research intends to construct a set of tissue microarrays containing different types of normal and lung cancer tissues for the study of genes associated with lung cancer. Thus...
Effect of Inhaled Steroids on Gene Expression in the Lungs - 2
The purpose of this study is to assess the effect of inhaled fluticasone (an inhaled corticosteroid) on the pattern of the lung airway epithelium and alveolar macrophages gene expression o...
The Changes of Patterns of Microarray in Patients With Obstructive Sleep Apnea
The aim of this study are (1) To genome-wide profile the gene expression patterns of peripheral blood mononuclear cell (PBMC) in patients with obstructive sleep apnea (OSA) (2) To profile...
Companies
Gene Expression Technologies Limited (GET) is a biopharmaceutical company established to develop and commercialise Gene ICE™, a unique and proprietary platform for gene expression regulation. This t...
Sequitur, Inc. was founded in 1996 to develop innovative sequence-based compounds for functional genomics research, diagnostic and therapeutic applications. Sequitur's proprietary antisense technolo...
MOLOGEN is specializing in selected areas of Molecular Medicine. Our areas of competence are gene expression, gene therapy and bioinformatics. We are dedicated to the development of DNA expression and...
Blue Heron Bio's GeneMaker® can synthesize any gene regardless of sequence, complexity, or size with 100% accuracy. Save time and money by ordering perfect clones from Blue Heron Bio. Go to ORDERING...
All living organisms have thousands to tens of thousands of unique genes encoded in their genome, of which only a small fraction, perhaps 15%, are expressed in any individual cell. Therefore, it is th...
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