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Locus Discovery Incorporated Company Profile

10:43 EDT 26th September 2017 | BioPortfolio

Locus Discovery Inc. is a privately held chemogenomics biopharmaceutical company organized in September 1999, and is based on technology exclusively licensed from the Sarnoff Corporation (SRI International). The Locus Discovery process is a novel computational approach for rapidly designing small molecule therapeutic compounds that can act as antagonists or agonists of protein activity.

Location

201 Washington Road, 3-075
Princeton
NJ
08543
United States of America

Contact

Phone: (215) 358 2000
Fax: (215) 358 2010
Email: locus-info@locusdiscovery.com


News Articles [473 Associated News Articles listed on BioPortfolio]

Locus Biosciences gets $5mm in debt financing

Locus Biosciences Inc. completed a $5mm convertible note financing led by Tencent Holdings, which was joined by North Carolina Biotechnology Center. The company will use the proceeds to develop CRISPR...

Study identifies first genetic locus for anorexia nervosa

A landmark study led by UNC School of Medicine researchers has identified the first genetic locus for anorexia nervosa and has revealed that there may also be metabolic underpinnings to this potential...

For anorexia nervosa, researchers implicate genetic locus on chromosome 12

(University of North Carolina Health Care) A landmark study led by UNC School of Medicine researchers has identified the first genetic locus for anorexia nervosa and has revealed that there may also b...

Locus Biosciences Secures $5m Convertible Note for CRISPR-Cas3 Antimicrobials

RESEARCH TRIANGLE PARK, N.C., July 10, 2017 /PRNewswire/ -- Locus Biosciences Inc. today announced the closing of a $5m Convertible Note to support the development of CRISPR-Cas3 antimicrobial therape...

An orthologous non-MHC locus in rats and mice is linked to CD4+ and CD8+ T-cell proportion

Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products

Peptide backbone N-methylation, as seen in cyclosporin A, has been considered to be exclusive to nonribosomal peptides. We have identified the first post-translationally modified peptide or protein ha...

Pharmacogenetics of oral antidiabetes drugs: evidence for diverse signals at the IRS1 locus

Locus Biosciences Secures $5M Convertible Note For CRISPR-Cas3 Antimicrobials

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PubMed Articles [952 Associated PubMed Articles listed on BioPortfolio]

Pedigree Analysis of Familial Primary Concomitant Horizontal Strabismus in Northern India.

Familial clustering of common forms of primary strabismus like esotropia (ET) and exotropia (XT) is observed in a proportion of the strabismus cohort. The genetic components of this remain unidentifie...

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.

In a previous work, a female-specific atherosclerosis risk locus on chromosome (Chr) 3 was identified in an intercross of atherosclerosis-resistant FVB and atherosclerosis-susceptible C57BL/6 (B6) mic...

Statistical correction of the Winner's Curse explains replication variability in quantitative trait genome-wide association studies.

Genome-wide association studies (GWAS) have identified hundreds of SNPs responsible for variation in human quantitative traits. However, genome-wide-significant associations often fail to replicate ac...

Role of Academic Drug Discovery in the Quest for New CNS Therapeutics.

There was a greater than 50% decline in central nervous system (CNS) drug discovery and development programs by major pharmaceutical companies from 2009 to 2014. This decline was paralleled by a rise ...

The unusual S locus of Leavenworthia is composed of two sets of paralogous loci.

The Leavenworthia self-incompatibility locus (S locus) consists of paralogs (Lal2, SCRL) of the canonical Brassicaceae S locus genes (SRK, SCR), and is situated in a genomic position that differs from...

Clinical Trials [182 Associated Clinical Trials listed on BioPortfolio]

Locus of Control and Spirituality in Palliative Care Patients

Primary Objectives: 1. To determine whether the degree of spirituality/religiosity as determined by the Duke University Religion Index and Functional Assessment of Chronic Illness ...

Discovery Elbow Multi-Center Prospective Study

The purpose of this prospective clinical trial is to document the performance and clinical outcomes of Biomet Discovery Elbow.

LOC387715/HTRA1 Variants in Polypoidal Choroidal Vasculopathy in a Korean Population

This study is to investigate whether variants in the LOC387715 locus and the HtrA serine peptidase 1 (HTRA1) gene within the 10q26 locus are associated with polypoidal choroidal vasculopat...

A Clinical Investigation of the Discovery™ Elbow System

The purpose of this study is to perform a five-year, multi-center prospective evaluation of the Discovery™ Elbow System for outcome and durability. Relief of pain and restoration of fun...

Endometriosis Biomarker Discovery Study

This is a prospective, Single time point, discovery study intending to identify biomarkers that can differentiate endometriosis from other underlying reasons for pelvic pain. Patients unde...

Companies [1097 Associated Companies listed on BioPortfolio]

Locus Discovery Incorporated

Locus Discovery Inc. is a privately held chemogenomics biopharmaceutical company organized in September 1999, and is based on technology exclusively licensed from the Sarnoff Corporation (SRI Internat...

PRAECIS PHARMACEUTICALS INCORPORATED

PRAECIS PHARMACEUTICALS INCORPORATED is a biopharmaceutical company focused on the discovery and development of novel compounds to address unmet medical needs or improve existing therapies.PRAECIS has...

Locus Pharmaceuticals, Inc.

Locus Pharmaceuticals is a privately held pharmaceutical company focused on developing novel, small molecule therapeutic drugs to address major unmet medical needs. The foundation and competitiveness ...

Locus Genex Oy

Monoclonal Antibodies to Human Neurotransmitter Substances.manufacturer and supplier of monoclonals antibodies.

Discovery Health

Discovery Health Media includes the Discovery Health and FitTV television networks and online assets, including www.discoveryhealth.com, as well as its Continuing Medical Education (CME) business and ...

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