NeoKimia Incorporated Company Profile

18:32 EDT 19th September 2017 | BioPortfolio

NEOKIMIA is a chemistry-based discovery company that integrates advanced synthesis and combinatorial chemistry capabilities with computational methods to produce libraries of novel, potentially bioactive molecules. The main component of the highly versatile, patented NEOKIMIA technology platform is the design and synthesis of conformationally defined, sophisticated macrocyclic molecules in a parallel fashion using (primarily) modern automated solid phase technologies. Appropriate recognition elements (small molecule building blocks, some of which are commercially available and others that are prepared internally) are assembled in a stepwise fashion together with a unique segment (a "tether" specially designed by NEOKIMIA) that restricts the molecule to specific spatial orientations. With the aid of computational techniques, the design of these macrocyclic libraries is based on consideration of diversity in terms of chemical composition, three-dimensional shape, and appropriate physical properties (Lipinski Rules of Five). To date, more than 35,000 macrocycles have been produced utilizing this proprietary approach. The versatility provided by this unique combination of diversity in terms of structure and conformation yields an extremely powerful discovery technique with applications in a wide variety of therapeutically relevant biological systems.


3001, 12e Avenue Nord - IPS
J1H 5N4


Phone: 819-820-6840
Fax: 819-820-6841

News Articles [2 Associated News Articles listed on BioPortfolio]

Corcept Therapeutics Announces Presentations on Mifepristone for the Treatment of Patients with Hypercortisolism at the American Association of Clinical Endocrinologists 26th Annual Congress

MENLO PARK, CA -- (Marketwired) -- 05/04/17 -- Corcept Therapeutics Incorporated (NASDAQ: CORT), a pharmaceutical company engaged in the discovery, development and commercialization of drugs that tre...

Milestone Scientific Announces Children's Hospital of Pittsburgh to use The Wand(R) Computer Assisted Anesthesia System for Pediatric Patients

LIVINGSTON, NJ --(Marketwired - September 14, 2017) - Milestone Scientific Inc. (NYSE American: MLSS) (NYSE MKT: MLSS), a medical company that develops and commercializes a growing portfolio of propri...

PubMed Articles [1 Associated PubMed Articles listed on BioPortfolio]


Dry powder inhalers (DPIs) have been among the fastest developing inhaler forms in the past decades. Researches are focusing on the formulation of carrier-free powders to obtain a higher deep-lung dep...

Clinical Trials [0 Results]


Companies [36 Associated Companies listed on BioPortfolio]

NeoKimia Incorporated

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